Elastase promotes aortic dilation by inhibiting Ca2+ influx into vascular smooth muscle

Journal of Cardiovascular Pharmacology

Volumn 43, Issue 4, 2004, Pages 504-513

  Chew, David K W ^b   Orshal, Julia M ^b   Khalil, Raouf A ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b NONE

Author keywords

Aortic aneurysm; Calcium; Contraction; Elastase; Smooth muscle

Indexed keywords

CALCIUM 45; CALCIUM ION; ELASTASE; ELASTIN; PHENYLEPHRINE; POTASSIUM CHLORIDE; PROSTAGLANDIN F2 ALPHA; SCLEROPROTEIN; VASOCONSTRICTOR AGENT; CALCIUM; PANCREATIC ELASTASE;

ABDOMINAL AORTA ANEURYSM; ANIMAL TISSUE; AORTA MEDIA; ARTICLE; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CALCIUM TRANSPORT; CONTROLLED STUDY; ENZYME ACTIVITY; EXTRACELLULAR MATRIX; HISTOPATHOLOGY; MALE; MEMBRANE DEPOLARIZATION; MUSCLE ISOMETRIC CONTRACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; RAT; VASODILATATION; ABDOMINAL AORTA; ANIMAL; COMPARATIVE STUDY; DOSE RESPONSE; DRUG EFFECT; IN VITRO STUDY; METABOLISM; PHYSIOLOGY; SPRAGUE DAWLEY RAT; THORACIC AORTA; VASCULAR SMOOTH MUSCLE; VASOCONSTRICTION;

ANIMALS; AORTA, ABDOMINAL; AORTA, THORACIC; CALCIUM; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; MUSCLE, SMOOTH, VASCULAR; PANCREATIC ELASTASE; RATS; RATS, SPRAGUE-DAWLEY; VASOCONSTRICTION; VASODILATION;

EID: 3042570794     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-200404000-00005     Document Type: Article

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