Elastin stabilization for treatment of abdominal aortic aneurysms

Circulation

Volumn 115, Issue 13, 2007, Pages 1729-1737

  Isenburg, Jason C ^a   Simionescu, Dan T ^a   Starcher, Barry C ^b   Vyavahare, Narendra R ^a  

^a AMRL   (United States)

^b UNIVERSITY OF TEXAS HEALTH CENTER   (United States)

Author keywords

Aneurysm; Aorta; Drug delivery systems; Elasticity; Metalloproteinases; Prevention; Tannins

Indexed keywords

ELASTIN; GLUCOSE PENTAGALLATE; METALLOPROTEINASE; POLYPHENOL; SODIUM CHLORIDE; CALCIUM CHLORIDE; GELATINASE A; GELATINASE B; TANNIN;

ABDOMINAL AORTA ANEURYSM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA; AORTA INJURY; ARTICLE; CALCIFICATION; CELL LEVEL; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG PROTEIN BINDING; ENZYME ACTIVITY; EXPERIMENTAL MODEL; EXPERIMENTAL RAT; HYPOTHESIS; IN VIVO STUDY; INFLAMMATION; INFLAMMATORY CELL; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN STABILITY; RAT; TREATMENT RESPONSE; ABDOMINAL AORTA; ANIMAL; CALCINOSIS; CELL CULTURE; CHEMICALLY INDUCED DISORDER; CHEMISTRY; CYTOLOGY; DISEASE COURSE; DISEASE MODEL; DRUG EFFECT; DRUG SCREENING; ENZYMOLOGY; FIBROBLAST; PATHOLOGY; PROTEIN DENATURATION; SMOOTH MUSCLE FIBER; SPRAGUE DAWLEY RAT; TOPICAL DRUG ADMINISTRATION; VASCULAR SMOOTH MUSCLE;

ADMINISTRATION, TOPICAL; ANIMALS; AORTA, ABDOMINAL; AORTIC ANEURYSM, ABDOMINAL; CALCINOSIS; CALCIUM CHLORIDE; CELLS, CULTURED; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; DRUG EVALUATION, PRECLINICAL; ELASTIN; FIBROBLASTS; HYDROLYZABLE TANNINS; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PROTEIN DENATURATION; RATS; RATS, SPRAGUE-DAWLEY;

EID: 34247234007     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.106.672873     Document Type: Article

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