Elastic fiber assembly is disrupted by excessive accumulation of chondroitin sulfate in the human dermal fibrotic disease, keloid

Biochemical and Biophysical Research Communications

Volumn 390, Issue 4, 2009, Pages 1221-1228

  Ikeda, Mika ^a   Naitoh, Motoko ^a   Kubota, Hiroshi ^b   Ishiko, Toshihiro ^a   Yoshikawa, Katsuhiro ^a   Yamawaki, Satoko ^a   Kurokawa, Masato ^c   Utani, Atsushi ^a   Nakamura, Tomoyuki ^d   Nagata, Kazuhiro ^b   Suzuki, Shigehiko ^a  

^a KYOTO UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c NAGAHAMA RED CROSS HOSPITAL   (Japan)

^d KANSAI MEDICAL UNIVERSITY   (Japan)

Author keywords

Chondroitin sulfate; DANCE fibulin 5; Elastic fibers; Glycosaminoglycan; Keloid; Wound healing

Indexed keywords

DERMATAN SULFATE; ELASTIN; FIBRILLIN 1; FIBULIN 5;

ADOLESCENT; ADULT; AGED; ARTICLE; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; ELASTIC FIBER; ENZYME INHIBITION; EXTRACELLULAR MATRIX; FIBROBLAST; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; HUMAN TISSUE; KELOID; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN EXPRESSION; PROTEIN PURIFICATION; PROTEIN SECRETION; SCHOOL CHILD; SKIN ABSORPTION;

ADOLESCENT; ADULT; AGED; CHILD; CHONDROITIN SULFATES; ELASTIC TISSUE; FEMALE; HUMANS; KELOID; MALE; MIDDLE AGED; SKIN DISEASES; YOUNG ADULT;

EID: 70450267456     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.10.125     Document Type: Article

References (29)

1. Heenan P.J. In: Elder D. (Ed). Lever's Histopathology of the Skin. eighth ed. (1997), Lippincott-Raven Publishers, Philadelphia 847-887
2. Naitoh M., Kubota H., Ikeda M., Tanaka T., Shirane H., Suzuki S., and Nagata K. Gene expression in human keloids is altered from dermal to chondrocytic and osteogenic lineage. Genes Cells 10 (2005) 1081-1091
3. Peltonen J., Hsiao L.L., Jaakkola S., Sollberg S., Aumailley M., Timpl R., Chu M.L., and Uitto J. Activation of collagen gene expression in keloids: co-localization of type I and VI collagen and transforming growth factor-beta 1 mRNA. J. Invest. Dermatol. 97 (1991) 240-248
4. Naitoh M., Hosokawa N., Kubota H., Tanaka T., Shirane H., Sawada M., Nishimura Y., and Nagata K. Upregulation of HSP47 and collagen type III in the dermal fibrotic disease, keloid. Biochem. Biophys. Res. Commun. 280 (2001) 1316-1322
5. Taylor K.R., and Gallo R.L. Glycosaminoglycans and their proteoglycans: host-associated molecular patterns for initiation and modulation of inflammation. FASEB J. 20 (2006) 9-22
6. Swann D.A., Garg H.G., Jung W., and Hermann H. Studies on human scar tissue proteoglycans. J. Invest. Dermatol. 84 (1985) 527-531
7. Bhangoo K.S., Quinlivan J.K., and Connelly J.R. Elastin fibers in scar tissue. Plast. Reconstr. Surg. 57 (1976) 308-313
8. Kamath N.V., Ormsby A., Bergfeld W.F., and House N.S. A light microscopic and immunohistochemical evaluation of scars. J. Cutan. Pathol. 29 (2002) 27-32
9. Rosenbloom J., Abrams W.R., and Mecham R. Extracellular matrix 4: the elastic fiber. FASEB J. 7 (1993) 1208-1218
10. Kielty C.M., Sherratt M.J., and Shuttleworth C.A. Elastic fibres. J. Cell Sci. 115 (2002) 2817-2828
11. Carta L., Pereira L., Arteaga-Solis E., Lee-Arteaga S.Y., Lenart B., Starcher B., Merkel C.A., Sukoyan M., Kerkis A., Hazeki N., Keene D.R., Sakai L.Y., and Ramirez F. Fibrillins 1 and 2 perform partially overlapping functions during aortic development. J. Biol. Chem. 281 (2006) 8016-8023
12. Nakamura T., Lozano P.R., Ikeda Y., Iwanaga Y., Hinek A., Minamisawa S., Cheng C.F., Kobuke K., Dalton N., Takada Y., Tashiro K., Ross Jr. J., Honjo T., and Chien K.R. Fibulin-5/DANCE is essential for elastogenesis in vivo. Nature 415 (2002) 171-175
13. Yanagisawa H., Davis E.C., Starcher B.C., Ouchi T., Yanagisawa M., Richardson J.A., and Olson E.N. Fibulin-5 is an elastin-binding protein essential for elastic fibre development in vivo. Nature 415 (2002) 168-171
14. Hirai M., Ohbayashi T., Horiguchi M., Okawa K., Hagiwara A., Chien K.R., Kita T., and Nakamura T. Fibulin-5/DANCE has an elastogenic organizer activity that is abrogated by proteolytic cleavage in vivo. J. Cell Biol. 176 (2007) 1061-1071
15. Hinek A., Braun K.R., Liu K., Wang Y., and Wight T.N. Retrovirally mediated overexpression of versican v3 reverses impaired elastogenesis and heightened proliferation exhibited by fibroblasts from Costello syndrome and Hurler disease patients. Am. J. Pathol. 164 (2004) 119-131
16. Mecham R.P. Modulation of elastin synthesis: in vitro models. Methods Enzymol. 144 (1987) 232-246
17. Shinmei M., Miyauchi S., Machida A., and Miyazaki K. Quantitation of chondroitin 4-sulfate and chondroitin 6-sulfate in pathologic joint fluid. Arthritis Rheum. 35 (1992) 1304-1308
18. Yamada H., Miyauchi S., Morita M., Yoshida Y., Yoshihara Y., Kikuchi T., Washimi O., Washimi Y., Terada N., Seki T., and Fujikawa K. Content and sulfation pattern of keratan sulfate in hip osteoarthritis using high performance liquid chromatography. J. Rheumatol. 27 (2000) 1721-1724
19. Takazono I., and Tanaka Y. Quantitative analysis of hyaluronic acid by high-performance liquid chromatography of streptomyces hyaluronidase digests. J. Chromatogr. 288 (1984) 167-176
20. Roark E.F., Keene D.R., Haudenschild C.C., Godyna S., Little C.D., and Argraves W.S. The association of human fibulin-1 with elastic fibers: an immunohistological, ultrastructural, and RNA study. J. Histochem. Cytochem. 43 (1995) 401-411
21. Zanetti M., Braghetta P., Sabatelli P., Mura I., Doliana R., Colombatti A., Volpin D., Bonaldo P., and Bressan G.M. EMILIN-1 deficiency induces elastogenesis and vascular cell defects. Mol. Cell. Biol. 24 (2004) 638-650
22. Jensen S.A., Reinhardt D.P., Gibson M.A., and Weiss A.S. Protein interaction studies of MAGP-1 with tropoelastin and fibrillin-1. J. Biol. Chem. 276 (2001) 39661-39666
23. Hinek A., Mecham R.P., Keeley F., and Rabinovitch M. Impaired elastin fiber assembly related to reduced 67-kD elastin-binding protein in fetal lamb ductus arteriosus and in cultured aortic smooth muscle cells treated with chondroitin sulfate. J. Clin. Invest. 88 (1991) 2083-2094
24. Tajima S., and Nagai Y. Distribution of macromolecular components in calf dermal connective tissue. Connect. Tissue Res. 7 (1980) 65-71
25. Huang R., Merrilees M.J., Braun K., Beaumont B., Lemire J., Clowes A.W., Hinek A., and Wight T.N. Inhibition of versican synthesis by antisense alters smooth muscle cell phenotype and induces elastic fiber formation in vitro and in neointima after vessel injury. Circ. Res. 98 (2006) 370-377
26. Wight T.N. Versican: a versatile extracellular matrix proteoglycan in cell biology. Curr. Opin. Cell Biol. 14 (2002) 617-623
27. Merrilees M.J., Lemire J.M., Fischer J.W., Kinsella M.G., Braun K.R., Clowes A.W., and Wight T.N. Retrovirally mediated overexpression of versican v3 by arterial smooth muscle cells induces tropoelastin synthesis and elastic fiber formation in vitro and in neointima after vascular injury. Circ. Res. 90 (2002) 481-487
28. Dietz H.C., Cutting G.R., Pyeritz R.E., Maslen C.L., Sakai L.Y., Corson G.M., Puffenberger E.G., Hamosh A., Nanthakumar E.J., Curristin S.M., Stetten G., Meyers D.A., and Francomano C.A. Marfan syndrome caused by a recurrent de novo missense mutation in the fibrillin gene. Nature 352 (1991) 337-339
29. Costa A.M., Peyrol S., Porto L.C., Comparin J.P., Foyatier J.L., and Desmouliere A. Mechanical forces induce scar remodeling. Study in non-pressure-treated versus pressure-treated hypertrophic scars. Am. J. Pathol. 155 (1999) 1671-1679