Inhibition of protein kinase CK2 closes the CFTR Cl channel, but has no effect on the cystic fibrosis mutant Δf508-CFTR

Cellular Physiology and Biochemistry

Volumn 24, Issue 5-6, 2009, Pages 347-360

  Treharne, Kate J ^a   Xu, Zhe ^b   Chen, Jeng Haur ^b   Best, O Giles ^a   Cassidy, Diane M ^a   Gruenert, Dieter C ^c,d   Hegyi, Péter ^e   Gray, Michael A ^f   Sheppard, David N ^b   Kunzelmann, Karl ^e,g   Mehta, Anil ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b UNIVERSITY OF BRISTOL   (United Kingdom)

^c CALIFORNIA PACIFIC MEDICAL CENTER   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF SZEGED   (Hungary)

^f NEWCASTLE UNIVERSITY   (United Kingdom)

^g UNIVERSITY OF REGENSBURG   (Germany)

Author keywords

ATP binding cassette transporter; CFTR; Channel regulation; Chloride ion channel; Cystic fibrosis; Protein kinase CK2

Indexed keywords

CASEIN KINASE II; CHLORIDE CHANNEL; CYCLIC AMP DEPENDENT PROTEIN KINASE; MUTANT PROTEIN; TRANSMEMBRANE CONDUCTANCE REGULATOR;

AIRWAY; ALLOSTERISM; ANIMAL CELL; APICAL MEMBRANE; ARTICLE; CELL MEMBRANE; CHLORIDE CURRENT; CHLORIDE TRANSPORT; CONSENSUS SEQUENCE; CONTROLLED STUDY; CYSTIC FIBROSIS; ELECTROPHYSIOLOGY; ENZYME ACTIVATION; ENZYME INHIBITION; GENE DELETION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; LUNG BIOPSY; NONHUMAN; OOCYTE; PANCREAS DUCT; PRECIPITATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; WILD TYPE; XENOPUS LAEVIS;

EID: 70450230597     PISSN: 10158987     EISSN: None     Source Type: Journal    
DOI: 10.1159/000257427     Document Type: Article

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