IFN-γ reverses the stop signal allowing migration of antigen-specific T cells into inflammatory sites

Journal of Immunology

Volumn 170, Issue 6, 2003, Pages 3315-3322

  Tay, Szun S ^a   McCormack, Ann ^a   Lawson, Charlotte ^a   Rose, Marlene L ^a  

^a HAREFIELD HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD45 ANTIGEN; FLUORESCENT DYE; GAMMA INTERFERON; HLA DR1 ANTIGEN; HLA DR11 ANTIGEN; HLA DR13 ANTIGEN; HLA DR2 ANTIGEN; HLA DR4 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; UNCLASSIFIED DRUG;

ALLOIMMUNITY; ANTIGEN EXPRESSION; ANTIGEN SPECIFICITY; ARTICLE; CELL LABELING; CONTROLLED STUDY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; LYMPHOCYTE CLONE; LYMPHOCYTE MIGRATION; LYMPHOCYTE PROLIFERATION; PRIORITY JOURNAL; PROTEIN FUNCTION; SYNAPSE;

EID: 0037443559     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.170.6.3315     Document Type: Article

References (61)

1. Springer, T. 1994. Traffic signals for lymphocyte recirculation: the multistep paradigm. Cell 76:301.
2. Lawrence, M. B., G. S. Kansas, E. J. Kunkel, and K. Ley. 1997. Threshold levels of fluid shear promote leukocyte adhesion through selectins (CD62L, P. E). J. Cell Biol. 136:717.
3. Yago, T., M. Tsukuda, H. Yamazaki, T. Nishi, T. Amano, and M. Minami. 1995. Analysis of an initial step of T cell adhesion to endothelial monolayers under flow conditions. J. Immunol. 154:1216
4. Ebnet, K., and D. Vestweber. 1999. Molecular mechanisms that control leukocyte extravasation: the selectins and the chemokines. Histochem. Cell. Biol. 112:1.
5. Szabo, M. C., E. C. Butcher, B. W. McIntyre, T. J. Schall, and K. Bacon. 1997. RANTES stimulation of T lymphocyte adhesion and activation: role for LFA-1 and ICAM-3. Eur. J. Immunol. 27:1061.
6. 1-mediated function. J. Cell Biol. 138:1437.
7. 2 integrins on naive peripheral lymphocytes. J. Exp. Med. 184:1343.
8. Kavanaugh, A. F., E. Lightfoot, P. E. Lipsky, and N. Oppenheimer-Marks. 1991. Role of CD11/CD18 in adhesion and transendothelial migration of T cells: analysis utilizing CD18-deficient T cell clones. J. Immunol. 146:4149.
9. Oppenheimer-Marks, N., L. S. Davis, and P. E. Lipsky. 1990. Human T lymphocyte adhesion to endothelial cells and transendothelial migration. Alteration of receptor use relates to the activation status of both the T cell and the endothelial cell. J. Immunol. 145:140.
10. Oppenheimer-Marks, N., L. S. Davis, D. T. Bogue, J. Ramberg, and P. E. Lipsky. 1991. Differential utilization of ICAM-1 and VCAM-1 during the adhesion and transendothelial migration of human T lymphocytes. J. Immunol. 147:2913.
11. Reiss, Y., and B, Engelhardt. 1999. T cell interaction with ICAM-1-deficient endothelium in vitro: transendothelial migration of different T cell populations is mediated by endothelial ICAM-1 and ICAM-2. Int. Immunol. 11:1527.
12. Chan, P., and A. Aruffo. 1993. VLA-4 integrin mediates lymphocyte migration on the inducible endothelial cell ligand VCAM-1 and the extracellular matrix ligand fibronectin. J. Biol. Chem. 268:24655.
13. Bianchi, E., J. R. Bender, F. Blasi, and R. Pardi. 1997. Through and beyond the wall: late steps in leukocyte transendothelial migration. Immunol. Today 18:586.
14. Johnson-Leger, C., M. Aurrand-Lions, and B. A. Imhof. 2000. The parting of the endothelium: miracle, or simply a junctional affair? J. Cell Sci. 113:921.
15. Butcher, E. C., and L. J. Picker. 1996. Lymphocyte homing and homeostasis, Science 272:60.
16. Watson, S. R., and L. M. Bradley. 1998. The recirculation of naive and memory lymphocytes. Cell Adhesion Commun. 6:105.
17. Picker, L. J., R. J. Martin, A. Trumble, L. S. Newman, P. A. Collins, P. R. Bergstresser, and D. Y. Leung. 1994. Differential expression of lymphocyte homing receptors by human memory/effector T cells in pulmonary versus cutaneous immune effector sites. Eur. J. Immunol. 24:1269.
18. 4 integrins in lymphocyte homing to mucosal tissues in vivo. J. Immunol. 152:3282.
19. Mackay, C. R. 1999. Dual personality of memory T cells. Nature 401:659.
20. Sallusto, F., D. Lenig, R. Forster, M. Lipp, and A. Lanzavecchia. 1999. Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature 401:708.
21. Berg, E. L., M. K. Robinson, A. Warnock, E. C. Butcher, 1991. The human peripheral lymph node vascular addressin is a ligand for LECAM-1, the peripheral lymph node homing receptor. J. Cell Biol. 114:343.
22. Berg, E. L., M. K. Robinson, A. Warnock, and E. C. Butcher. 1991. The human peripheral lymph node vascular addressin is a ligand for LECAM-1, the peripheral lymph node homing receptor. J. Cell Biol. 114:343.
23. Daar, A. S., S. V. Fuggle, J. W. Fabre, A. Ting, and P. J. Morris. 1984. The detailed distribution of MHC class II antigens in normal human organs. Transplantation 38:293.
24. Rose, M. L., M. I. Coles, R. J. Griffin, A. Pomerance, and M. H. Yacoub. 1986. Expression of class I and class II major histocompatibility antigens in normal and transplanted human heart. Transplantation 41:776.
25. Savage, C. O. S., C. J. Brooks, G. C. Harcourt, J. K. Picard, W. King, D. M. Sansom, and N. Willcox. 1995. Human vascular EC process and present autoantigen to human TCL. Int. Immunol. 7:471.
26. Bosse, D., V. George, F. J. Candal, T. J. Lawley, and E. W. Ades. 1993. Antigen presentation by a continous human microvascular endothelial cell line, HMEC-1, to human T cells. Pathobiology 61:236.
27. Haraldsen, G., L. M. Sollid, O. Bakke. I. N. Farstad, D. Kvale, K. D. Molberg, J. Norstein, E. Stang, and P. Brandtzaeg. 1998. Major histocompatability complex class II-dependent antigen presentation by human intestinal endothelial cells. Gastroenterology 114:649.
28. Vora, M., H. Yssel, J. E. de Vries, and M. A. Karasek. 1994. Antigen presentation by human dermal microvascular endothelial cells: immunoregulatory effect of IFN-γ and IL-10. J. Immunol. 152:5734.
29. Geppert, T. D., and P. E. Lipsky. 1985. Antigen presentation by interferon-γ-treated endothelial cells and fibroblasts: differential ability to function as antigen-presenting cells despite comparable Ia expression. J. Immunol. 135:3750.
30. Hughes, C. C., and J. S. Pober, 1993. Costimulation of peripheral blood T cell activation by human endothelial cells: enhanced IL-2 transcription correlates with increased c-fos synthesis and increased Fos content of AP-1. J. Immunol. 150:3148.
31. + allogeneic vascular endothelium: identification of accessory interactions. Transplantation 56:128.
32. + T cells to endothelial cells in the absence of contaminating accessory cells. Transplantation 57:1628.
33. Adams, P. W., H. S. Lee, W. J. Waldman, D. D. Semak, C. J. Morgan, J. S. Ward, and O. C. G. 1992. Alloantigenicity of human endothelial cells. I. Frequency and phenotype of human T helper lymphocytes that can react to allogeneic endothelial cells. J. Immunol. 148:3753.
34. Hughes, C. C., C. O. Savage, and J. S. Pober, 1990. EC augment T cell IL-2 production by a contact-dependent mechanism involving CD2/LFA-3 interaction. J. Exp. Med. 171:1453.
35. Page, C. S., C. Thompson, M. Yacoub, and M. Rose. 1994. Human endothelial stimulation of allogeneic T cells via a CTLA-4 independent pathway. Transplant Immunology 2:342.
36. Westphal, J. R., H. W. Willems, W. J. Tax, R. A. Koene, D. J. Ruiter, and R. M. De Waal. 1993. The proliferative response of human T cells to allogeneic IFN-γ-treated endothelial cells is mediated via both CD2/LFA-3 and LFA-1/ICAM adhesion pathways, Transplant. Immunol. 1:183.
37. Lakkis F. G., A. Arakelov, B. T. Konieczny, and Y. Inoue Y. 2000. Immunologic 'ignorance' of vascularized organ transplants in the absence of secondary lymphoid tissue. Nat. Med. 6:686.
38. + T cells. J. Immunol. 162:696.
39. Suitters, A. J., M. L. Rose, M. J. Domingues, and M. H. Yacoub. 1990. Selection for donor-specific cytotoxic T lymphocytes within the allografted human heart. Transplantation 49:1105.
40. Zeevi, A., J. Fung, T. R. Zerbe, C. Kaufman, R. B. S., B. P. Griffith, R. L. Hardesty, and R. J. Duquesnoy, 1986. Allospecificity of activated T cells grown from endomyocardial biopsies from heart transplant patients. Transplantation 41:620.
41. Borgonovo, B., G. Casorati, E. Frittoli, D. Gaffi, E. Crimi, and S. E. Burastero. 1997. Recruitment of circulating allergen-specific T lymphocytes to the lung on allergen challenge in asthma. J. Allergy Clin. Immunol. 100:669.
42. Kawai, T., H. Shimauchi, J. W. Eastcott, D. J. Smith, and M. A. Taubman. 1998. Antigen direction of specific T cell clones into gingival tissues. Immunology 93:11.
43. Edgell, C., C. McDonald, and J. Graham. 1983. Permanent cell line expressing human factor VIII-related antigen established by hybridisation. Proc. Natl. Acad. Sci. USA 80:3734.
44. Lidington, E. A., D. L. Moyes, A. M. McCormack, and M. L. Rose. 1999. A comparison of primary endothelial cells and endothelial cell lines for studies of immune interactions. Transplant. Immunol. 7:239.
45. + T cells, but not after IFN-γ stimulation. J. Immunol. 165:734.
46. Welsh, K., and M. Bunce. 1999. Molecular typing for the MHC with PCR-SSP. Rev. Immunogenet. 1:157.
47. Lidington, E., C. Nohammer, M. Domingues, B. Ferry, and M. L. Rose. 1996. Inhibition of the transendothelial migration of human lymphocytes but not monocytes by phosphodiesterase inhibitos. Clin. Exp. Immunol. 104:66.
48. Pitzalis, C., G. H. Kingsley, M. Corelli, R. Meliconi, A. Markey, and G. S. Panayi. 1991. Selective migration of the human helper-inducer memory T cell subset: confirmation by in vivo cellular kinetic studies. Eur. J. Immunol. 21:369.
49. Kawai, T., M. Seki, H. Watanabe, J. W. Eastcott, D. J. Smith, and M. A. Taubman. 2000. T(h)1 transmigration anergy: a new concept of endothelial cell-T cell regulatory interaction. Int. Immunol. 12:937.
50. Beverly, B., S. Kang, M. J. Lenardo, and R. H. Schwartz. 1992. Reversal of in vitro T cell clonal anergy by IL-2 stimulation. Int. Immunol. 4:661.
51. Marelli-Berg, F. M., R. E. Hargreaves, P. Carmichael, A. Dorling, G. Lombardi, and R. I. Lechler. 1996. Major histocompatibility complex class II-expressing endothelial cells induce allospecific nonresponsiveness in naive T cells. J. Exp. Med. 183:1603.
52. Dustin, M. 1997. Antigen receptor engagement delivers a stop signal to migrating T lymphocytes. Proc. Natl. Acad. Sci. USA 94:3909.
53. Dustin, M., and T. Springer. 1989. T-cell receptor cross-liniking transiently stimulates adhesiveness through LFA-1. Nature 341:619.
54. Martin-Padura, I., S. Lostaglio, M. Schneemann, L. Williams, M. Romano, P. Fruscella, C. Panzeri, A. Stoppacciaro, L. Ruco, A. Villa, et al. 1998. Junctional adhesion molecule, a novel member of the immunoglobulin superfamily that distributes at intercellular junctions and modulates monocyte transmigration. J. Cell Biol. 142:117.
55. 2 integrin LFA-1 involved in transendothelial migration of leukocytes. Nat. Immunol. 3:151.
56. Marfaing-Koka, A., O. Devergne, G. Gorgone, A. Portier, T. J. Schall, P. Galanaud, and D. Emilie. 1994. Regulation of the production of RANTES chemokine by endothelial cells. J. Immunol. 154:1870.
57. Brown, Z., M. E. Gemtsen Gerritsen. W. W. Carley, R. M. Strieter Stricter, S. L. Kunkel, and J. Westwick. 1994. Chemokine gene expression and secretion by cytokine-activated human microvascular endothelial cells. Am. J. Pathol. 145:913.
58. Bromley, S. K., D. A. Peterson, M. D. Gunn, and M. L. Dustin. 2000. Cutting edge: hierarchy of chemokine receptor and TCR signals regulating T cell migration and proliferation. J. Immunol. 165:15.
59. Bradley, J. R., and J. S. Pober. 1996. Prolonged cytokine exposure causes a dynamic redistribution of endothelial cell adhesion molecules to intercellular junctions. Lab. Invest. 75:463.
60. Ozaki. H., K. Ishii, H. Horiuchi, H. Arai, T. Kawamoto. K. Okawa, A. Iwamatsu, and T. Kita. 1999. Cutting edge: combined treatment of TNF-α and IFN-γ causes redistribution of junctional adhesion molecule in human endothelial cells. J. Immunol. 163:553.
61. Hickey, M. J. M. Forster, D. Mitchell, J Kaur, C. De Caigny, and P Kubes. 2000. L-selectin facilitates emigration and extravascular locomotion of leukocytes during acute inflammatory responses in vivo. J. Immunol. 165:7164.