An amino acid substitution in PBP-3 in Haemophilus influenzae associate with the invasion to bronchial epithelial cells

Microbiological Research

Volumn 165, Issue 1, 2010, Pages 11-20

  Okabe, Tadashi ^a   Yamazaki, Yoshitaka ^a   Shiotani, Miho ^a   Suzuki, Takefumi ^a   Shiohara, Mayumi ^a   Kasuga, Eriko ^a   Notake, Shigeyuki ^b   Yanagisawa, Hideji ^b  

^a SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b Miroku Medical Laboratory Inc   (Japan)

Author keywords

Clarithromycin; fts I; Non typeable Haemophilus influenzae

Indexed keywords

AMINO ACID SUBSTITUTION; B CELLS; BLUE STAINING; CLARITHROMYCIN; EPITHELIAL CELLS; EPITHELIUM CELLS; EXTRACELLULAR; HAEMOPHILUS INFLUENZAE; INTRACELLULAR BACTERIA; LACTAMASES; PENICILLIN- BINDING PROTEINS;

AMINATION; AMINES; AMINO ACIDS; BACTERIOLOGY; CELL CULTURE; CELLS; ENZYME ACTIVITY; ORGANIC ACIDS; PLASMAS;

ACID RESISTANCE;

AMPICILLIN; PENICILLIN BINDING PROTEIN;

AMINO ACID; ANTIBIOTIC RESISTANCE; BACTERIUM; CYTOPLASM; ELECTRON MICROSCOPY; INVASIVE SPECIES; RESPIRATORY DISEASE;

AMINO ACID SUBSTITUTION; ARTICLE; BRONCHUS; CELL LINE; CYTOLOGY; DRUG EFFECT; EPITHELIUM CELL; GENETICS; HAEMOPHILUS INFECTION; HAEMOPHILUS INFLUENZAE; HUMAN; METABOLISM; MICROBIOLOGY; MISSENSE MUTATION; PENICILLIN RESISTANCE; PHYSIOLOGY;

AMINO ACID SUBSTITUTION; AMPICILLIN; AMPICILLIN RESISTANCE; BRONCHI; CELL LINE; EPITHELIAL CELLS; HAEMOPHILUS INFECTIONS; HAEMOPHILUS INFLUENZAE; HUMANS; MUTATION, MISSENSE; PENICILLIN-BINDING PROTEINS;

BACTERIA (MICROORGANISMS); HAEMOPHILUS INFLUENZAE;

EID: 70450222343     PISSN: 09445013     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.micres.2008.03.003     Document Type: Article

References (35)

1. Bartlett J.G., Dowell S.F., Mandell L.A., File Jr. T.M., Musher D.M., and Fine M.J. Practice guidelines for the management of community-acquired pneumonia in adults. Infectious Diseases Society of America. Clin Infect Dis 31 (2000) 347-382
2. Bosnar M., Kelneric Z., Munic V., Erakovic V., and Parnham M.J. Cellular uptake and efflux of azithromycin, erythromycin, clarithromycin, telithromycin, and cethromycin. Antimicrob Agents Chemother 49 (2005) 2372-2377
3. Bouchet V., Hood D.W., Li J., Brisson J.R., Randle G.A., Martin A., et al. Host-derived sialic acid is incorporated into Haemophilus influenzae lipopolysaccharide and is a major virulence factor in experimental otitis media. Proc Natl Acad Sci USA 100 (2003) 8898-8903
4. Craig W.A. Pharmacokinetic/pharmacodynamic parameters: rationale for antibacterial dosing of mice and men. Clin Infect Dis 26 (1998) 1-10
5. Dabernat H., Delmas C., Seguy M., Pelissier R., Faucon G., Bennamani S., et al. Diversity of beta-lactam resistance-conferring amino acid substitutions in penicillin-binding protein 3 of Haemophilus influenzae. Antimicrob Agents Chemother 46 (2002) 2208-2218
6. Ehrlich G.D., Veeh R., Wang X., Costerton J.W., Hayes J.D., Hu F.Z., et al. Mucosal biofilm formation on middle-ear mucosa in the chinchilla model of otitis media. JAMA 287 (2002) 1710-1715
7. Flesher A.R., and Insel R.A. Characterization of lipopolysaccharide of Haemophilus influenzae. J Infect Dis 138 (1978) 719-730
8. Fluit A.C., Florijn A., Verhoef J., and Milatovic D. Susceptibility of European beta-lactamase-positive and -negative Haemophilus influenzae isolates from the periods 1997/1998 and 2002/2003. J Antimicrob Chemother 56 (2005) 133-138
9. Forsgren J., Samuelson A., Ahlin A., Jonasson J., Rynnel-Dagoo B., and Lindberg A. Haemophilus influenzae resides and multiplies intracellularly in human adenoid tissue as demonstrated by in situ hybridization and bacterial viability assay. Infect Immun 62 (1994) 673-679
10. Gantois I., Ducatelle R., Pasmans F., Haesebrouck F., Hautefort I., Thompson A., et al. Butyrate specifically down-regulates salmonella pathogenicity island 1 gene expression. Appl Environ Microbiol 72 (2006) 946-949
11. García-Cobos S., Campos J., Lázaro E., Román F., Cercenado E., García-Rey C., et al. Ampicillin-resistant non-beta-lactamase-producing Haemophilus influenzae in Spain: recent emergence of clonal isolates with increased resistance to cefotaxime and cefixime. Antimicrob Agents Chemother 51 (2007) 2564-2573
12. Gotschlich E.C., Fraser C.A., Nishimura O., Robbinsand J.B., and Liu T.Y. Lipid on capsular polysaccharides of gram negative bacteria. J Biol Chem 256 (1981) 8915-8921
13. Holmes K.A., and Bakaletz L.O. Adherence of non-typeable Haemophilus influenzae promotes reorganization of the actin cytoskeleton in human or chinchilla epithelial cells in vitro. Microb Pathog 23 (1997) 157-166
14. Hotomi M., Fujihara K., Billal D.S., Suzuki K., Nishimura T., Baba S., et al. Genetic characteristics and clonal dissemination of beta-lactamase-negative ampicillin-resistant Haemophilus influenzae strains isolated from the upper respiratory tract of patients in Japan. Antimicrob Agents Chemother 51 (2007) 3969-3976
15. Johri A.K., Margarit I., Broenstrup M., Brettoni C., Hua L., Gygi S.P., et al. Transcriptional and proteomic profiles of group B Streptococcus type V reveal potential adherence proteins associated with high-level invasion. Infect Immun 75 (2007) 1473-1483
16. Jones A.T. Macropinocytosis: searching for an endocytic identity and a role in the uptake of cell penetrating peptides. J Cell Mol Med 11 (2007) 670-684
17. Karlowsky J.A., Critchley I.A., Blosser-Middleton R.S., Karginova E.A., Jones M.E., Thornsberry C., et al. Antimicrobial surveillance of Haemophilus influenzae in the United State during 2000-2001 leads to detection of clonal dissemination of a beta-lactamase-negative and ampicillin-resistant strain. J Clin Microbiol 40 (2002) 1063-1066
18. Ketterer M.R., Shao J.Q., Hornick D.B., Buscher B., Bandi V.K., and Apicella M.A. Infection of primary human bronchial epithelial cells by Haemophilus influenzae: macropinocytosis as a mechanism of airway epithelial cell entry. Infect Immun 67 (1999) 4161-4170
19. Kunishima H., Takemura H., Yamamoto H., Kanemitsu K., and Shimada J. Evaluation of the activity of antimicrobial agents against Legionella pneumophila multiplying in a human monocytic cell line, THP-1, and an alveolar epithelial cell line, A549. J Infect Chemother 6 (2000) 206-210
20. Kuo J.S.C., Doelling V.W., Graveline J.F., and McCoy D.W. Evidence for covalent attachment of phospholipids to the capsular polysaccharide of Haemophilus influenzae type b. J Bacteriol 163 (1985) 769-773
21. Marino M., and McCluskey R.T. Role of thyroglobulin endocytic pathways in the control of thyroid hormone release. Am J Physiol Cell Physiol 279 (2000) C1295-C1306
22. Mendelman P.M., Chaffin D.O., and Kalaitzoglou G. Penicillin-binding proteins and ampicillin resistance in Haemophilus influenzae. J Antimicrob Chemother 25 (1990) 525-534
23. Murphy T.F. The role of bacteria in airway inflammation in exacerbations of chronic obstructive pulmonary disease. Curr Opin Infect Dis 19 (2006) 225-230
24. Murphy T.F., and Apicella M.A. Nontypable Haemophilus influenzae: a review of clinical aspects, surface antigens, and the human immune response to infection. Rev Infect Dis 9 (1987) 1-15
25. Parr Jr. T.R., and Bryan L.E. Mechanism of resistance of an ampicillin-resistant, beta-lactamase-negative clinical isolate of Haemophilus influenzae type b to beta-lactam antibiotics. Antimicrob Agents Chemother 25 (1984) 747-753
26. Pfaller M.A., Ehrhardt A.F., and Jones R.N. Frequency of pathogen occurrence and antimicrobial susceptibility among community-acquired respiratory tract infections in the respiratory surveillance program study: microbiology from the medical office practice environment. Am J Med 111 Suppl. 9A (2001) 4S-12S [discussion 36S-38S]
27. Reddel R.R., Salghetti S.E., Willey J.C., Ohnuki Y., Ke Y., Gerwin B.I., et al. Development of tumorigenicity in simian virus 40-immortalized human bronchial epithelial cell lines. Cancer Res 53 (1993) 985-991
28. Sanbongi Y., Suzuki T., Osaki Y., Senju N., Ida T., and Ubukata K. Molecular evolution of beta-lactam-resistant Haemophilus influenzae: 9-year surveillance of penicillin-binding protein 3 mutations in isolates from Japan. Antimicrob Agents Chemother 50 (2006) 2487-2492
29. Sapey E., and Stockley R.A. COPD exacerbations 2: aetiology. Thorax 61 (2006) 250-258
30. Sethi S., Evans N., Grant B.J., and Murphy T.F. New strains of bacteria and exacerbations of chronic obstructive pulmonary disease. N Engl J Med 347 (2002) 465-471
31. Swords W.E., Buscher B.A., Ver Steeg Ii K., Preston A., Nichols W.A., Weiser J.N., et al. Non-typeable Haemophilus influenzae adhere to and invade human bronchial epithelial cells via an interaction of lipooligosaccharide with the PAF receptor. Mol Microbiol 37 (2000) 13-27
32. Ubukata K., Shibasaki Y., Yamamoto K., Chiba N., Hasegawa K., Takeuchi Y., et al. Association of amino acid substitutions in penicillin-binding protein 3 with beta-lactam resistance in beta-lactamase-negative ampicillin-resistant Haemophilus influenzae. Antimicrob Agents Chemother 45 (2001) 1693-1699
33. Wang B., Cleary P.P., Xu H., and Li J.D. Up-regulation of interleukin-8 by novel small cytoplasmic molecules of nontypeable Haemophilus influenzae via p38 and extracellular signal-regulated kinase pathways. Infect Immun 71 (2003) 5523-5530
34. Weiser J.N., Maskell D.J., Butler P.D., Lindberg A.A., and Moxon E.R. Characterization of repetitive sequences controlling phase variation of Haemophilus influenzae lipopolysaccharide. J Bacteriol 172 (1990) 3304-3309
35. Yamazaki Y., Danelishvili L., Wu M., Hidaka E., Katsuyama T., Stang B., et al. The ability to form biofilm influences Mycobacterium avium invasion and translocation of bronchial epithelial cells. Cell Microbiol 8 (2006) 806-814