Neuropilin ligands in vascular and neuronal patterning

Biochemical Society Transactions

Volumn 37, Issue 6, 2009, Pages 1228-1232

  Fantin, Alessandro ^a   Maden, Charlotte H ^a   Ruhrberg, Christiana ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Blood vessel; Neural crest; Neuron; Neuropilin; Semaphorin; Vascular endothelial growth factor (VEGF)

Indexed keywords

NEUROPILIN 1; SEMAPHORIN 3A; VASCULOTROPIN A;

ANGIOGENESIS; ARTICLE; BINDING AFFINITY; BLOOD VESSEL; CELL MIGRATION; CORONARY ARTERY BLOOD FLOW; ENDOTHELIUM CELL; GENE EXPRESSION; GENE FUNCTION; GENE INTERACTION; HEART DEVELOPMENT; HUMAN; MOTOR NERVE; NERVE CELL; NERVE CELL DIFFERENTIATION; NERVE FIBER; NERVE REGENERATION; NEURAL CREST CELL; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SENSORY NERVE; SMOOTH MUSCLE FIBER; SYMPATHETIC NERVE CELL; VASCULAR SMOOTH MUSCLE;

ANIMALS; BLOOD VESSELS; HEART; LIGANDS; MICE; MORPHOGENESIS; NEURONS; NEUROPILIN-1; PROTEIN ISOFORMS; SEMAPHORIN-3A; SIGNAL TRANSDUCTION; STEM CELLS; SYMPATHETIC NERVOUS SYSTEM; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

MUS;

EID: 70450203386     PISSN: 03005127     EISSN: 14708752     Source Type: Journal    
DOI: 10.1042/BST0371228     Document Type: Article

References (46)

1. Larrivee, B., Freitas, C., Suchting, S., Brunet, I. and Eichmann, A. (2009) Guidance of vascular development: lessons from the nervous system. Circ. Res. 104, 428-441
2. Takagi, S., Hirata, T., Agata, K., Mochii, M., Eguchi, G. and Fujisawa, H. (1991) The A5 antigen, a candidate for the neuronal recognition molecule, has homologies to complement components and coagulation factors. Neuron 7, 295-307
3. Takagi, S., Kasuya, Y., Shimizu, M., Matsuura, T., Tsuboi, M., Kawakami, A. and Fujisawa, H. (1995) Expression of a cell adhesion molecule, neuropilin, in the developing chick nervous system. Dev. Biol. 170, 207-222
4. He, Z. and Tessier-Lavigne, M. (1997) Neuropilin is a receptor for the axonal chemorepellent Semaphorin III. Cell 90, 739-751
5. Kolodkin, A.L., Levengood, D.V., Rowe, E.G., Tai, Y.T., Giger, R.J. and Ginty, D.D. (1997) Neuropilin is a semaphorin III receptor. Cell 90, 753-762
6. Soker, S., Takashima, S., Miao, H.Q., Neufeld, G. and Klagsbrun, M. (1998) Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor. Cell 92, 735-745
7. Chen, H., Chedotal, A., He, Z., Goodman, C.S. and Tessier-Lavigne, M. (1997) Neuropilin-2, a novel member of the neuropilin family, is a high affinity receptor for the semaphorins Sema E and Sema IV but not Sema III. Neuron 19, 547-559
8. Gluzman-Poltorak, Z., Cohen, T., Herzog, Y. and Neufeld, G. (2000) Neuropilin-2 is a receptor for the vascular endothelial growth factor (VEGF) forms VEGF-145 and VEGF-165. J. Biol. Chem. 275, 18040-18045
9. Shimizu, M., Murakami, Y., Suto, F. and Fujisawa, H. (2000) Determination of cell adhesion sites of neuropilin-1. J. Cell Biol. 148, 1283-1293
10. Feiner, L., Koppel, A.M., Kobayashi, H. and Raper, J.A. (1997) Secreted chick semaphorins bind recombinant neuropilin with similar affinities but bind different subsets of neurons in situ. Neuron 19, 539-545
11. Takahashi, T., Fournier, A., Nakamura, F., Wang, L.H., Murakami, Y., Kalb, R.G., Fujisawa, H. and Strittmatter, S.M. (1999) Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors. Cell 99, 59-69
12. Luo, Y., Raible, D. and Raper, J.A. (1993) Collapsin: a protein in brain that induces the collapse and paralysis of neuronal growth cones. Cell 75, 217-227
13. Taniguchi, M., Yuasa, S., Fujisawa, H., Naruse, I., Saga, S., Mishina, M. and Yagi, T. (1997) Disruption of semaphorin III/D gene causes severe abnormality in peripheral nerve projection. Neuron 19, 519-530
14. Gu, C., Rodriguez, E.R., Reimert, D.V., Shu, T., Fritzsch, B., Richards, L.J., Kolodkin, A.L. and Ginty, D.D. (2003) Neuropilin-1 conveys semaphorin and VEGF signaling during neural and cardiovascular development. Dev. Cell 5, 45-57
15. Kitsukawa, T., Shimizu, M., Sanbo, M., Hirata, T., Taniguchi, M., Bekku, Y., Yagi, T. and Fujisawa, H. (1997) Neuropilin-semaphorin III/ D-mediated chemorepulsive signals play a crucial role in peripheral nerve projection in mice. Neuron 19, 995-1005
16. Vieira, J.M., Schwarz, Q. and Ruhrberg, C. (2007) Selective requirements for NRP1 ligands during neurovascular patterning. Development 134, 1833-1843
17. Schwarz, Q., Gu, C., Fujisawa, H., Sabelko, K., Gertsenstein, M., Nagy, A., Taniguchi, M., Kolodkin, A.L., Ginty, D.D., Shima, D.T. and Ruhrberg, C. (2004) Vascular endothelial growth factor controls neuronal migration and cooperates with Sema3A to pattern distinct compartments of the facial nerve. Genes Dev. 18, 2822-2834
18. Kitsukawa, T., Shimono, A., Kawakami, A., Kondoh, H. and Fujisawa, H. (1995) Overexpression of a membrane protein, neuropilin, in chimeric mice causes anomalies in the cardiovascular system, nervous system and limbs. Development 121, 4309-4318
19. Kawasaki, T., Kitsukawa, T., Bekku, Y., Matsuda, Y., Sanbo, M., Yagi, T. and Fujisawa, H. (1999) A requirement for neuropilin-1 in embryonic vessel formation. Development 126, 4895-4902
20. 121. J. Biol. Chem. 276, 25520-25531
21. Salikhova, A., Wang, L., Lanahan, A.A., Liu, M., Simons, M., Leenders, W.P., Mukhopadhyay, D. and Horowitz, A. (2008) Vascular endothelial growth factor and semaphorin induce neuropilin-1 endocytosis via separate pathways. Circ. Res. 103, e71-e79
22. 165-receptor binding. J. Cell. Biochem. 85, 357-368
23. Yamada, Y., Oike, Y., Ogawa, H., Ito, Y., Fujisawa, H., Suda, T. and Takakura, N. (2003) Neuropilin-1 on hematopoietic cells as a source of vascular development. Blood 101, 1801-1809
24. Gerhardt, H., Ruhrberg, C., Abramsson, A., Fujisawa, H., Shima, D. and Betsholtz, C. (2004) Neuropilin-1 is required for endothelial tip cell guidance in the developing central nervous system. Dev. Dyn. 231, 503-509
25. Ruhrberg, C., Gerhardt, H., Golding, M., Watson, R., Ioannidou, S., Fujisawa, H., Betsholtz, C. and Shima, D.T. (2002) Spatially restricted patterning cues provided by heparin-binding VEGF-A control blood vessel branching morphogenesis. Genes Dev. 16, 2684-2698
26. Miao, H.Q., Soker, S., Feiner, L., Alonso, J.L., Raper, J.A. and Klagsbrun, M. (1999) Neuropilin-1 mediates collapsin-1/semaphorin III inhibition of endothelial cell motility: functional competition of collapsin-1 and vascular endothelial growth factor-165. J. Cell Biol. 146, 233-242
27. Appleton, B.A., Wu, P., Maloney, J., Yin, J., Liang, W.C., Stawicki, S., Mortara, K., Bowman, K.K., Elliott, J.M., Desmarais, W. et al. (2007) Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding. EMBO J. 26, 4902-4912
28. Serini, G., Valdembri, D., Zanivan, S., Morterra, G., Burkhardt, C., Caccavari, F., Zammataro, L., Primo, L., Tamagnone, L., Logan, M. et al. (2003) Class 3 semaphorins control vascular morphogenesis by inhibiting integrin function. Nature 424, 391-397
29. Murga, M., Fernandez-Capetillo, O. and Tosato, G. (2005) Neuropilin-1 regulates attachment in human endothelial cells independently of vascular endothelial growth factor receptor-2. Blood 105, 1992-1999
30. West, D.C., Rees, C.G., Duchesne, L., Patey, S.J., Terry, C.J., Turnbull, J.E., Delehedde, M., Heegaard, C.W., Allain, F., Vanpouille, C. et al. (2005) Interactions of multiple heparin binding growth factors with neuropilin-1 and potentiation of the activity of fibroblast growth factor-2. J. Biol. Chem. 280, 13457-13464
31. Castellani, V., Chedotal, A., Schachner, M., Faivre-Sarrailh, C. and Rougon, G. (2000) Analysis of the L1-deficient mouse phenotype reveals cross-talk between Sema3A and L1 signaling pathways in axonal guidance. Neuron 27, 237-249
32. Fukasawa, M., Matsushita, A. and Korc, M. (2007) Neuropilin-1 interacts with integrin β1 and modulates pancreatic cancer cell growth, survival and invasion. Cancer Biol. Ther. 6, 1173-1180
33. Valdembri, D., Caswell, P.T., Anderson, K.I., Schwarz, J.P., Konig, I., Astanina, E., Caccavari, F., Norman, J.C., Humphries, M.J., Bussolino, F. and Serini, G. (2009) Neuropilin-1/GIPC1 signaling regulates α5β1 integrin traffic and function in endothelial cells. PLoS Biol. 7, e25
34. Ieda, M., Kanazawa, H., Kimura, K., Hattori, F., Ieda, Y., Taniguchi, M., Lee, J.K., Matsumura, K., Tomita, Y., Miyoshi, S. et al. (2007) Sema3a maintains normal heart rhythm through sympathetic innervation patterning. Nat. Med. 13, 604-612
35. Kawasaki, T., Bekku, Y., Suto, F., Kitsukawa, T., Taniguchi, M., Nagatsu, I., Nagatsu, T., Itoh, K., Yagi, T. and Fujisawa, H. (2002) Requirement of neuropilin 1-mediated Sema3A signals in patterning of the sympathetic nervous system. Development 129, 671-680
36. Schwarz, Q., Maden, C.H., Vieira, J.M. and Ruhrberg, C. (2009) Neuropilin 1 signaling guides neural crest cells to coordinate pathway choice with cell specification. Proc. Natl. Acad. Sci. U.S.A. 106, 6164-6169
37. Le Douarin, N.M. and Kalcheim, C. (1999) The Neural Crest, Cambridge University Press, Cambridge
38. Eickholt, B.J., Mackenzie, S.L., Graham, A., Walsh, F.S. and Doherty, P. (1999) Evidence for collapsin-1 functioning in the control of neural crest migration in both trunk and hindbrain regions. Development 126, 2181-2189
39. Schwarz, Q., Vieira, J.M., Howard, B., Eickholt, B.J. and Ruhrberg, C. (2008) Neuropilin 1 and 2 control cranial gangliogenesis and axon guidance through neural crest cells. Development 135, 1605-1613
40. Marko, S.B. and Damon, D.H. (2008) VEGF promotes vascular sympathetic innervation. Am. J. Physiol. Heart Circ. Physiol. 294, H2646-H2652
41. Stoller, J.Z. and Epstein, J.A. (2005) Cardiac neural crest. Semin. Cell Dev. Biol. 16, 704-715
42. Stalmans, I., Lambrechts, D., De Smet, F., Jansen, S., Wang, J., Maity, S., Kneer, P., von der Ohe, M., Swillen, A., Maes, C. et al. (2003) VEGF: a modifier of the del22q11 (DiGeorge) syndrome? Nat. Med. 9, 173-182
43. Feiner, L., Webber, A.L., Brown, C.B., Lu, M.M., Jia, L., Feinstein, P., Mombaerts, P., Epstein, J.A. and Raper, J.A. (2001) Targeted disruption of semaphorin 3C leads to persistent truncus arteriosus and aortic arch interruption. Development 128, 3061-3070
44. Gitler, A.D., Lu, M.M. and Epstein, J.A. (2004) PlexinD1 and semaphorin signaling are required in endothelial cells for cardiovascular development. Dev. Cell 7, 107-116
45. Takahashi, T., Nakamura, F., Jin, Z., Kalb, R.G. and Strittmatter, S.M. (1998) Semaphorins A and E act as antagonists of neuropilin-1 and agonists of neuropilin-2 receptors. Nat. Neurosci. 1, 487-493
46. Toyofuku, T., Yoshida, J., Sugimoto, T., Yamamoto, M., Makino, N., Takamatsu, H., Takegahara, N., Suto, F., Hori, M., Fujisawa, H. et al. (2008) Repulsive and attractive semaphorins cooperate to direct the navigation of cardiac neural crest cells. Dev. Biol. 321, 251-262