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Volumn 36, Issue 4, 2009, Pages 881-900

Neonatal Seizures: An Update on Mechanisms and Management

Author keywords

aminobutyric acid (GABA); Epilepsy; Glutamate; Neurotransmitter receptor; Perinatal; Synapse

Indexed keywords

1 [N,O BIS(5 ISOQUINOLINESULFONYL) N METHYLTYROSYL] 4 PHENYLPIPERAZINE; 4 (N ETHYL N PHENYLAMINO) 1,2 DIMETHYL 6 (METHYLAMINO)PYRIMIDINIUM CHLORIDE; AMPA RECEPTOR ANTAGONIST; ANTICONVULSIVE AGENT; BARBITURIC ACID DERIVATIVE; BENZODIAZEPINE DERIVATIVE; BUMETANIDE; CHELERYTHRINE; DIAZEPAM; DOXYCYCLINE; ERYTHROPOIETIN; ETIRACETAM; FELBAMATE; FOSPHENYTOIN SODIUM; IFENPRODIL; KT 5720; LIDOCAINE; LORAZEPAM; MEMANTINE; MIDAZOLAM; MINOCYCLINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; PHENOBARBITAL; PHENYTOIN; PYRIDOXINE; TACROLIMUS; TALAMPANEL; TOPIRAMATE; UNINDEXED DRUG; VALPROIC ACID;

EID: 70450196839     PISSN: 00955108     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clp.2009.08.001     Document Type: Review
Times cited : (125)

References (134)
  • 1
    • 0027500117 scopus 로고
    • Electrographic seizures in preterm and full-term neonates: clinical correlates, associated brain lesions, and risk for neurologic sequelae
    • Scher M.S., Aso K., Beggarly M.E., et al. Electrographic seizures in preterm and full-term neonates: clinical correlates, associated brain lesions, and risk for neurologic sequelae. Pediatrics 91 (1993) 128-134
    • (1993) Pediatrics , vol.91 , pp. 128-134
    • Scher, M.S.1    Aso, K.2    Beggarly, M.E.3
  • 2
    • 0032912953 scopus 로고    scopus 로고
    • The epidemiology of clinical neonatal seizures in Newfoundland: a population-based study
    • Ronen G.M., Penney S., and Andrews W. The epidemiology of clinical neonatal seizures in Newfoundland: a population-based study. J Pediatr 134 1 (1999) 71-75
    • (1999) J Pediatr , vol.134 , Issue.1 , pp. 71-75
    • Ronen, G.M.1    Penney, S.2    Andrews, W.3
  • 3
    • 0033214109 scopus 로고    scopus 로고
    • Incidence of neonatal seizures in Harris County, Texas, 1992-1994
    • Saliba R.M., Annegers J.F., Waller D.K., et al. Incidence of neonatal seizures in Harris County, Texas, 1992-1994. Am J Epidemiol 150 7 (1999) 763-769
    • (1999) Am J Epidemiol , vol.150 , Issue.7 , pp. 763-769
    • Saliba, R.M.1    Annegers, J.F.2    Waller, D.K.3
  • 4
    • 33646380349 scopus 로고    scopus 로고
    • The current etiologic profile and neurodevelopmental outcome of seizures in term newborn infants
    • Tekgul H., Gauvreau K., Soul J., et al. The current etiologic profile and neurodevelopmental outcome of seizures in term newborn infants. Pediatrics 117 (2006) 1270-1280
    • (2006) Pediatrics , vol.117 , pp. 1270-1280
    • Tekgul, H.1    Gauvreau, K.2    Soul, J.3
  • 6
    • 35948966025 scopus 로고    scopus 로고
    • Long-term prognosis in children with neonatal seizures: a population-based study
    • Ronen G.M., Buckley D., Penney S., et al. Long-term prognosis in children with neonatal seizures: a population-based study. Neurology 69 19 (2007) 1816-1822
    • (2007) Neurology , vol.69 , Issue.19 , pp. 1816-1822
    • Ronen, G.M.1    Buckley, D.2    Penney, S.3
  • 7
    • 0021233678 scopus 로고
    • Neonatal hypoxia and epileptic risk: a clinical prospective study
    • Bergamasco B., Penna P., Ferrero P., et al. Neonatal hypoxia and epileptic risk: a clinical prospective study. Epilepsia 25 (1984) 131-146
    • (1984) Epilepsia , vol.25 , pp. 131-146
    • Bergamasco, B.1    Penna, P.2    Ferrero, P.3
  • 8
    • 26444452073 scopus 로고    scopus 로고
    • Whole-body hypothermia for neonates with hypoxic-ischemic encephalopathy
    • Shankaran S., Laptook A.R., Ehrenkranz R.A., et al. Whole-body hypothermia for neonates with hypoxic-ischemic encephalopathy. N Engl J Med 353 15 (2005) 1574-1584
    • (2005) N Engl J Med , vol.353 , Issue.15 , pp. 1574-1584
    • Shankaran, S.1    Laptook, A.R.2    Ehrenkranz, R.A.3
  • 9
    • 13844321255 scopus 로고    scopus 로고
    • Selective head cooling with mild systemic hypothermia after neonatal encephalopathy: multicentre randomised trial
    • Gluckman P.D., Wyatt J.S., Azzopardi D., et al. Selective head cooling with mild systemic hypothermia after neonatal encephalopathy: multicentre randomised trial. Lancet 365 9460 (2005) 663-670
    • (2005) Lancet , vol.365 , Issue.9460 , pp. 663-670
    • Gluckman, P.D.1    Wyatt, J.S.2    Azzopardi, D.3
  • 10
    • 10744231473 scopus 로고    scopus 로고
    • + channel mutation in benign neonatal convulsions and centrotemporal spikes
    • + channel mutation in benign neonatal convulsions and centrotemporal spikes. Neurology 61 1 (2003) 131-134
    • (2003) Neurology , vol.61 , Issue.1 , pp. 131-134
    • Coppola, G.1    Castaldo, P.2    Miraglia del Giudice, E.3
  • 11
    • 0344012023 scopus 로고    scopus 로고
    • KCNQ2 and KCNQ3 potassium channel genes in benign familial neonatal convulsions: expansion of the functional and mutation spectrum
    • Singh N.A., Westenskow P., Charlier C., et al. KCNQ2 and KCNQ3 potassium channel genes in benign familial neonatal convulsions: expansion of the functional and mutation spectrum. Brain 126 Pt 12 (2003) 2726-2737
    • (2003) Brain , vol.126 , Issue.PART 12 , pp. 2726-2737
    • Singh, N.A.1    Westenskow, P.2    Charlier, C.3
  • 12
    • 32044452240 scopus 로고    scopus 로고
    • Mutational scanning of potassium, sodium and chloride ion channels in malignant migrating partial seizures in infancy
    • Coppola G., Veggiotti P., Del Giudice E.M., et al. Mutational scanning of potassium, sodium and chloride ion channels in malignant migrating partial seizures in infancy. Brain Dev 28 2 (2006) 76-79
    • (2006) Brain Dev , vol.28 , Issue.2 , pp. 76-79
    • Coppola, G.1    Veggiotti, P.2    Del Giudice, E.M.3
  • 13
    • 10444290761 scopus 로고    scopus 로고
    • De novo KCNQ2 mutations in patients with benign neonatal seizures
    • Claes L.R., Ceulemans B., Audenaert D., et al. De novo KCNQ2 mutations in patients with benign neonatal seizures. Neurology 63 11 (2004) 2155-2158
    • (2004) Neurology , vol.63 , Issue.11 , pp. 2155-2158
    • Claes, L.R.1    Ceulemans, B.2    Audenaert, D.3
  • 14
    • 0019943440 scopus 로고
    • Neonatal seizures. I. Correlation of prenatal and perinatal events with outcomes
    • Holden K.R., Mellits E.D., and Freeman J.M. Neonatal seizures. I. Correlation of prenatal and perinatal events with outcomes. Pediatrics 70 2 (1982) 165-176
    • (1982) Pediatrics , vol.70 , Issue.2 , pp. 165-176
    • Holden, K.R.1    Mellits, E.D.2    Freeman, J.M.3
  • 15
    • 0033841360 scopus 로고    scopus 로고
    • Electrographic seizures in neonates correlate with poor neurodevelopmental outcome
    • McBride M.C., Laroia N., and Guillet R. Electrographic seizures in neonates correlate with poor neurodevelopmental outcome. Neurology 55 4 (2000) 506-513
    • (2000) Neurology , vol.55 , Issue.4 , pp. 506-513
    • McBride, M.C.1    Laroia, N.2    Guillet, R.3
  • 16
    • 69249216499 scopus 로고    scopus 로고
    • Clinical neonatal seizures are independently associated with outcome in infants at risk for hypoxic-ischemic brain injury
    • Glass H.C., Glidden D., Jeremy R.J., et al. Clinical neonatal seizures are independently associated with outcome in infants at risk for hypoxic-ischemic brain injury. J Pediatr 155 3 (2009) 318-323
    • (2009) J Pediatr , vol.155 , Issue.3 , pp. 318-323
    • Glass, H.C.1    Glidden, D.2    Jeremy, R.J.3
  • 17
    • 20144386669 scopus 로고    scopus 로고
    • Patterns of brain injury in term neonatal encephalopathy
    • Miller S.P., Ramaswamy V., Michelson D., et al. Patterns of brain injury in term neonatal encephalopathy. J Pediatr 146 4 (2005) 453-460
    • (2005) J Pediatr , vol.146 , Issue.4 , pp. 453-460
    • Miller, S.P.1    Ramaswamy, V.2    Michelson, D.3
  • 18
    • 1842486052 scopus 로고    scopus 로고
    • Risk factors for neonatal seizures in very low birthweight infants: population-based survey
    • Kohelet D., Shochat R., Lusky A., et al. Risk factors for neonatal seizures in very low birthweight infants: population-based survey. J Child Neurol 19 2 (2004) 123-128
    • (2004) J Child Neurol , vol.19 , Issue.2 , pp. 123-128
    • Kohelet, D.1    Shochat, R.2    Lusky, A.3
  • 19
    • 33846296221 scopus 로고    scopus 로고
    • Risk factors for seizures in very low birthweight infants with periventricular leukomalacia
    • Kohelet D., Shochat R., Lusky A., et al. Risk factors for seizures in very low birthweight infants with periventricular leukomalacia. J Child Neurol 21 11 (2006) 965-970
    • (2006) J Child Neurol , vol.21 , Issue.11 , pp. 965-970
    • Kohelet, D.1    Shochat, R.2    Lusky, A.3
  • 21
    • 33748089307 scopus 로고    scopus 로고
    • Prolonged electroencephalogram monitoring for seizures and their treatment
    • vi
    • Clancy R.R. Prolonged electroencephalogram monitoring for seizures and their treatment. Clin Perinatol 33 3 (2006) 649-665 vi
    • (2006) Clin Perinatol , vol.33 , Issue.3 , pp. 649-665
    • Clancy, R.R.1
  • 22
    • 35148856609 scopus 로고    scopus 로고
    • Sensitivity of amplitude-integrated electroencephalography for neonatal seizure detection
    • Shellhaas R.A., Soaita A.I., and Clancy R.R. Sensitivity of amplitude-integrated electroencephalography for neonatal seizure detection. Pediatrics 120 4 (2007) 770-777
    • (2007) Pediatrics , vol.120 , Issue.4 , pp. 770-777
    • Shellhaas, R.A.1    Soaita, A.I.2    Clancy, R.R.3
  • 23
    • 67349141458 scopus 로고    scopus 로고
    • A pilot study of continuous limited-channel aEEG in term infants with encephalopathy
    • e1
    • Lawrence R., Mathur A., Nguyen The Tich S., et al. A pilot study of continuous limited-channel aEEG in term infants with encephalopathy. J Pediatr 154 6 (2009) 835-841 e1
    • (2009) J Pediatr , vol.154 , Issue.6 , pp. 835-841
    • Lawrence, R.1    Mathur, A.2    Nguyen The Tich, S.3
  • 24
    • 13944257048 scopus 로고    scopus 로고
    • Electroencephalography in neonatal seizures: comparison of a reduced and a full 10/20 montage
    • Tekgul H., Bourgeois B.F., Gauvreau K., et al. Electroencephalography in neonatal seizures: comparison of a reduced and a full 10/20 montage. Pediatr Neurol 32 3 (2005) 155-161
    • (2005) Pediatr Neurol , vol.32 , Issue.3 , pp. 155-161
    • Tekgul, H.1    Bourgeois, B.F.2    Gauvreau, K.3
  • 25
    • 33744935249 scopus 로고    scopus 로고
    • Seizure detection algorithm for neonates based on wave-sequence analysis
    • Navakatikyan M.A., Colditz P.B., Burke C.J., et al. Seizure detection algorithm for neonates based on wave-sequence analysis. Clin Neurophysiol 117 6 (2006) 1190-1203
    • (2006) Clin Neurophysiol , vol.117 , Issue.6 , pp. 1190-1203
    • Navakatikyan, M.A.1    Colditz, P.B.2    Burke, C.J.3
  • 26
    • 34548534041 scopus 로고    scopus 로고
    • Characterization of neonatal seizures by conventional EEG and single-channel EEG
    • Shellhaas R.A., and Clancy R.R. Characterization of neonatal seizures by conventional EEG and single-channel EEG. Clin Neurophysiol 118 10 (2007) 2156-2161
    • (2007) Clin Neurophysiol , vol.118 , Issue.10 , pp. 2156-2161
    • Shellhaas, R.A.1    Clancy, R.R.2
  • 27
    • 33745543980 scopus 로고    scopus 로고
    • Summary proceedings from the neurology group on neonatal seizures
    • Clancy R.R. Summary proceedings from the neurology group on neonatal seizures. Pediatrics 117 3 Pt 2 (2006) S23-S27
    • (2006) Pediatrics , vol.117 , Issue.3 PART 2
    • Clancy, R.R.1
  • 28
    • 33748163533 scopus 로고    scopus 로고
    • Amplitude integrated electroencephalography in the full-term newborn
    • vi
    • de Vries L.S., and Toet M.C. Amplitude integrated electroencephalography in the full-term newborn. Clin Perinatol 33 3 (2006) 619-632 vi
    • (2006) Clin Perinatol , vol.33 , Issue.3 , pp. 619-632
    • de Vries, L.S.1    Toet, M.C.2
  • 29
    • 0034922363 scopus 로고    scopus 로고
    • Pyridoxine-dependent seizures responding to extremely low-dose pyridoxine
    • Grillo E., da Silva R.J., and Barbato Jr. J.H. Pyridoxine-dependent seizures responding to extremely low-dose pyridoxine. Dev Med Child Neurol 43 6 (2001) 413-415
    • (2001) Dev Med Child Neurol , vol.43 , Issue.6 , pp. 413-415
    • Grillo, E.1    da Silva, R.J.2    Barbato Jr., J.H.3
  • 30
    • 0034911419 scopus 로고    scopus 로고
    • Pyridoxine-dependent and pyridoxine-responsive seizures
    • Baxter P. Pyridoxine-dependent and pyridoxine-responsive seizures. Dev Med Child Neurol 43 6 (2001) 416-420
    • (2001) Dev Med Child Neurol , vol.43 , Issue.6 , pp. 416-420
    • Baxter, P.1
  • 31
    • 27744521455 scopus 로고    scopus 로고
    • Acute injury to the immature brain with hypoxia with or without hypoperfusion
    • viii
    • Grant P.E., and Yu D. Acute injury to the immature brain with hypoxia with or without hypoperfusion. Radiol Clin North Am 44 1 (2006) 63-77 viii
    • (2006) Radiol Clin North Am , vol.44 , Issue.1 , pp. 63-77
    • Grant, P.E.1    Yu, D.2
  • 32
    • 34547522707 scopus 로고    scopus 로고
    • Neonatal seizures: multi-center variability in current treatment practices
    • Bartha A., Shen J., Katz K.H., et al. Neonatal seizures: multi-center variability in current treatment practices. Pediatr Neurol Res 37 2 (2007) 85-90
    • (2007) Pediatr Neurol Res , vol.37 , Issue.2 , pp. 85-90
    • Bartha, A.1    Shen, J.2    Katz, K.H.3
  • 33
    • 14644390865 scopus 로고    scopus 로고
    • Neonatal seizures: after all these years we still love what doesn't work
    • Sankar R., and Painter M.J. Neonatal seizures: after all these years we still love what doesn't work. Neurology 64 5 (2005) 776-777
    • (2005) Neurology , vol.64 , Issue.5 , pp. 776-777
    • Sankar, R.1    Painter, M.J.2
  • 34
    • 16644393806 scopus 로고    scopus 로고
    • Anticonvulsants for neonates with seizures
    • CD004218
    • Booth D., and Evans D.J. Anticonvulsants for neonates with seizures. Cochrane Database Syst Rev 4 (2004) CD004218
    • (2004) Cochrane Database Syst Rev , Issue.4
    • Booth, D.1    Evans, D.J.2
  • 35
    • 0033549786 scopus 로고    scopus 로고
    • Phenobarbital compared with phenytoin for the treatment of neonatal seizures
    • Painter M.J., Scher M.S., Stein A.D., et al. Phenobarbital compared with phenytoin for the treatment of neonatal seizures. N Engl J Med 341 7 (1999) 485-489
    • (1999) N Engl J Med , vol.341 , Issue.7 , pp. 485-489
    • Painter, M.J.1    Scher, M.S.2    Stein, A.D.3
  • 36
    • 0033917037 scopus 로고    scopus 로고
    • Dynamic cerebral autoregulation in sick newborn infants
    • Boylan G.B., Young K., Panerai R.B., et al. Dynamic cerebral autoregulation in sick newborn infants. Pediatr Res 48 1 (2000) 12-17
    • (2000) Pediatr Res , vol.48 , Issue.1 , pp. 12-17
    • Boylan, G.B.1    Young, K.2    Panerai, R.B.3
  • 37
    • 22944478038 scopus 로고    scopus 로고
    • Drug treatment of neonatal seizures by neonatologists and paediatric neurologists
    • Carmo K.B., and Barr P. Drug treatment of neonatal seizures by neonatologists and paediatric neurologists. J Paediatr Child Health 41 7 (2005) 313-316
    • (2005) J Paediatr Child Health , vol.41 , Issue.7 , pp. 313-316
    • Carmo, K.B.1    Barr, P.2
  • 38
    • 33746481433 scopus 로고    scopus 로고
    • Development of an optimal lidocaine infusion strategy for neonatal seizures
    • Malingre M.M., Van Rooij L.G., Rademaker C.M., et al. Development of an optimal lidocaine infusion strategy for neonatal seizures. Eur J Pediatr 165 9 (2006) 598-604
    • (2006) Eur J Pediatr , vol.165 , Issue.9 , pp. 598-604
    • Malingre, M.M.1    Van Rooij, L.G.2    Rademaker, C.M.3
  • 39
    • 47049102489 scopus 로고    scopus 로고
    • Off-label use of antiepileptic drugs for the treatment of neonatal seizures
    • Silverstein F.S., and Ferriero D.M. Off-label use of antiepileptic drugs for the treatment of neonatal seizures. Pediatr Neurol 39 2 (2008) 77-79
    • (2008) Pediatr Neurol , vol.39 , Issue.2 , pp. 77-79
    • Silverstein, F.S.1    Ferriero, D.M.2
  • 40
    • 30144443849 scopus 로고    scopus 로고
    • Antiepileptic drugs trials: neonates and infants
    • Pellock J. Antiepileptic drugs trials: neonates and infants. Epilepsy Res 68 1 (2006) 42-45
    • (2006) Epilepsy Res , vol.68 , Issue.1 , pp. 42-45
    • Pellock, J.1
  • 41
    • 29244451059 scopus 로고    scopus 로고
    • Levetiracetam in a neonate with malignant migrating partial seizures
    • Hmaimess G., Kadhim H., Nassogne M.C., et al. Levetiracetam in a neonate with malignant migrating partial seizures. Pediatr Neurol 34 1 (2006) 55-59
    • (2006) Pediatr Neurol , vol.34 , Issue.1 , pp. 55-59
    • Hmaimess, G.1    Kadhim, H.2    Nassogne, M.C.3
  • 42
    • 44649200749 scopus 로고    scopus 로고
    • Cooling for newborns with hypoxic ischaemic encephalopathy
    • CD003311
    • Jacobs S., Hunt R., Tarnow-Mordi W., et al. Cooling for newborns with hypoxic ischaemic encephalopathy. Cochrane Database Syst Rev 4 (2007) CD003311
    • (2007) Cochrane Database Syst Rev , Issue.4
    • Jacobs, S.1    Hunt, R.2    Tarnow-Mordi, W.3
  • 43
    • 44949148032 scopus 로고    scopus 로고
    • The TOBY Study. Whole body hypothermia for the treatment of perinatal asphyxial encephalopathy: a randomised controlled trial
    • Azzopardi D., Brocklehurst P., Edwards D., et al. The TOBY Study. Whole body hypothermia for the treatment of perinatal asphyxial encephalopathy: a randomised controlled trial. BMC Pediatr 8 (2008) 17
    • (2008) BMC Pediatr , vol.8 , pp. 17
    • Azzopardi, D.1    Brocklehurst, P.2    Edwards, D.3
  • 44
    • 70350787254 scopus 로고    scopus 로고
    • Epileptogenesis in the immature brain: emerging mechanisms
    • Rakhade S.N., and Jensen F.E. Epileptogenesis in the immature brain: emerging mechanisms. Nat Rev Neurol 5 7 (2009) 380-391
    • (2009) Nat Rev Neurol , vol.5 , Issue.7 , pp. 380-391
    • Rakhade, S.N.1    Jensen, F.E.2
  • 45
    • 0027152087 scopus 로고
    • Incidence of epilepsy and unprovoked seizures in Rochester, Minnesota: 1935-1984
    • Hauser W.A., Annegers J.F., and Kurland L.T. Incidence of epilepsy and unprovoked seizures in Rochester, Minnesota: 1935-1984. Epilepsia 34 (1993) 453-468
    • (1993) Epilepsia , vol.34 , pp. 453-468
    • Hauser, W.A.1    Annegers, J.F.2    Kurland, L.T.3
  • 46
    • 0014807006 scopus 로고
    • Convulsive status epilepticus in infants and children. A study of 239 cases
    • Aicardi J., and Chevrie J.J. Convulsive status epilepticus in infants and children. A study of 239 cases. Epilepsia 11 2 (1970) 187-197
    • (1970) Epilepsia , vol.11 , Issue.2 , pp. 187-197
    • Aicardi, J.1    Chevrie, J.J.2
  • 47
    • 0035018620 scopus 로고    scopus 로고
    • Maturational aspects of epilepsy mechanisms and consequences for the immature brain
    • Sanchez R.M., and Jensen F.E. Maturational aspects of epilepsy mechanisms and consequences for the immature brain. Epilepsia 42 (2001) 577-585
    • (2001) Epilepsia , vol.42 , pp. 577-585
    • Sanchez, R.M.1    Jensen, F.E.2
  • 49
    • 33744940044 scopus 로고    scopus 로고
    • Developmental regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid receptor subunit expression in forebrain and relationship to regional susceptibility to hypoxic/ischemic injury. II. Human cerebral white matter and cortex
    • Talos D.M., Follett P.L., Folkerth R.D., et al. Developmental regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid receptor subunit expression in forebrain and relationship to regional susceptibility to hypoxic/ischemic injury. II. Human cerebral white matter and cortex. J Comp Neurol 497 1 (2006) 61-77
    • (2006) J Comp Neurol , vol.497 , Issue.1 , pp. 61-77
    • Talos, D.M.1    Follett, P.L.2    Folkerth, R.D.3
  • 50
    • 14644418492 scopus 로고    scopus 로고
    • Axonal development in the cerebral white matter of the human fetus and infant
    • Haynes R.L., Borenstein N.S., DeSilva T.M., et al. Axonal development in the cerebral white matter of the human fetus and infant. J Comp Neurol 484 2 (2005) 156-167
    • (2005) J Comp Neurol , vol.484 , Issue.2 , pp. 156-167
    • Haynes, R.L.1    Borenstein, N.S.2    DeSilva, T.M.3
  • 51
    • 0018830539 scopus 로고
    • Morphology of the developing visual cortex of the human infant: a quantitative and qualitative Golgi study
    • Takashima S., Chan F., Becker L.E., et al. Morphology of the developing visual cortex of the human infant: a quantitative and qualitative Golgi study. J Neuropathol Exp Neurol 39 4 (1980) 487-501
    • (1980) J Neuropathol Exp Neurol , vol.39 , Issue.4 , pp. 487-501
    • Takashima, S.1    Chan, F.2    Becker, L.E.3
  • 52
    • 0020262681 scopus 로고
    • Synaptogenesis in human visual cortex - evidence for synapse elimination during normal development
    • Huttenlocher P.R., deCourten C., Garey L.J., et al. Synaptogenesis in human visual cortex - evidence for synapse elimination during normal development. Neurosci Lett 33 (1982) 247-252
    • (1982) Neurosci Lett , vol.33 , pp. 247-252
    • Huttenlocher, P.R.1    deCourten, C.2    Garey, L.J.3
  • 53
    • 0028874967 scopus 로고
    • Neurotransmitters and vulnerability of the developing brain
    • Johnston M.V. Neurotransmitters and vulnerability of the developing brain. Brain Dev 17 5 (1995) 301-306
    • (1995) Brain Dev , vol.17 , Issue.5 , pp. 301-306
    • Johnston, M.V.1
  • 54
    • 33744916296 scopus 로고    scopus 로고
    • Developmental regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid receptor subunit expression in forebrain and relationship to regional susceptibility to hypoxic/ischemic injury. I. Rodent cerebral white matter and cortex
    • Talos D.M., Fishman R.E., Park H., et al. Developmental regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid receptor subunit expression in forebrain and relationship to regional susceptibility to hypoxic/ischemic injury. I. Rodent cerebral white matter and cortex. J Comp Neurol 497 1 (2006) 42-60
    • (2006) J Comp Neurol , vol.497 , Issue.1 , pp. 42-60
    • Talos, D.M.1    Fishman, R.E.2    Park, H.3
  • 55
    • 0035887598 scopus 로고    scopus 로고
    • Decreased glutamate receptor 2 expression and enhanced epileptogenesis in immature rat hippocampus after perinatal hypoxia-induced seizures
    • Sanchez R.M., Koh S., Rio C., et al. Decreased glutamate receptor 2 expression and enhanced epileptogenesis in immature rat hippocampus after perinatal hypoxia-induced seizures. J Neurosci 21 20 (2001) 8154-8163
    • (2001) J Neurosci , vol.21 , Issue.20 , pp. 8154-8163
    • Sanchez, R.M.1    Koh, S.2    Rio, C.3
  • 57
    • 34247344136 scopus 로고    scopus 로고
    • Alterations of NR2B and PSD-95 expression after early-life epileptiform discharges in developing neurons
    • Jiang Q., Wang J., Wu X., et al. Alterations of NR2B and PSD-95 expression after early-life epileptiform discharges in developing neurons. Int J Dev Neurosci 25 3 (2007) 165-170
    • (2007) Int J Dev Neurosci , vol.25 , Issue.3 , pp. 165-170
    • Jiang, Q.1    Wang, J.2    Wu, X.3
  • 58
    • 0037009161 scopus 로고    scopus 로고
    • Temporal and regional expression of NMDA receptor subunit NR3A in the mammalian brain
    • Wong H.K., Liu X.B., Matos M.F., et al. Temporal and regional expression of NMDA receptor subunit NR3A in the mammalian brain. J Comp Neurol 450 4 (2002) 303-317
    • (2002) J Comp Neurol , vol.450 , Issue.4 , pp. 303-317
    • Wong, H.K.1    Liu, X.B.2    Matos, M.F.3
  • 59
    • 0030940718 scopus 로고    scopus 로고
    • Acute effects of MK801 on kainic acid-induced seizures in neonatal rats
    • Stafstrom C.E., Tandon P., Hori A., et al. Acute effects of MK801 on kainic acid-induced seizures in neonatal rats. Epilepsy Res 26 2 (1997) 335-344
    • (1997) Epilepsy Res , vol.26 , Issue.2 , pp. 335-344
    • Stafstrom, C.E.1    Tandon, P.2    Hori, A.3
  • 60
    • 58149170714 scopus 로고    scopus 로고
    • Different effects of two N-methyl-d-aspartate receptor antagonists on seizures, spontaneous behavior, and motor performance in immature rats
    • Mares P., and Mikulecka A. Different effects of two N-methyl-d-aspartate receptor antagonists on seizures, spontaneous behavior, and motor performance in immature rats. Epilepsy Behav 14 1 (2009) 32-39
    • (2009) Epilepsy Behav , vol.14 , Issue.1 , pp. 32-39
    • Mares, P.1    Mikulecka, A.2
  • 61
    • 0032543788 scopus 로고    scopus 로고
    • Neuroprotective concentrations of the N-methyl-d-aspartate open-channel blocker memantine are effective without cytoplasmic vacuolation following post-ischemic administration and do not block maze learning or long-term potentiation
    • Chen H.S., Wang Y.F., Rayudu P.V., et al. Neuroprotective concentrations of the N-methyl-d-aspartate open-channel blocker memantine are effective without cytoplasmic vacuolation following post-ischemic administration and do not block maze learning or long-term potentiation. Neuroscience 86 4 (1998) 1121-1132
    • (1998) Neuroscience , vol.86 , Issue.4 , pp. 1121-1132
    • Chen, H.S.1    Wang, Y.F.2    Rayudu, P.V.3
  • 62
    • 0032947526 scopus 로고    scopus 로고
    • Blockade of NMDA receptors and apoptotic neurodegeneration in the developing brain
    • Ikonomidou C., Bosch F., Miksa M., et al. Blockade of NMDA receptors and apoptotic neurodegeneration in the developing brain. Science 283 (1999) 70-74
    • (1999) Science , vol.283 , pp. 70-74
    • Ikonomidou, C.1    Bosch, F.2    Miksa, M.3
  • 63
    • 0038389588 scopus 로고    scopus 로고
    • Antiepileptic drugs and apoptosis in the developing brain
    • [discussion: 123-4]
    • Bittigau P., Sifringer M., and Ikonomidou C. Antiepileptic drugs and apoptosis in the developing brain. Ann N Y Acad Sci 993 (2003) 103-114 [discussion: 123-4]
    • (2003) Ann N Y Acad Sci , vol.993 , pp. 103-114
    • Bittigau, P.1    Sifringer, M.2    Ikonomidou, C.3
  • 64
    • 48549090897 scopus 로고    scopus 로고
    • NMDA receptor blockade with memantine attenuates white matter injury in a rat model of periventricular leukomalacia
    • Manning S.M., Talos D.M., Zhou C., et al. NMDA receptor blockade with memantine attenuates white matter injury in a rat model of periventricular leukomalacia. J Neurosci 28 26 (2008) 6670-6678
    • (2008) J Neurosci , vol.28 , Issue.26 , pp. 6670-6678
    • Manning, S.M.1    Talos, D.M.2    Zhou, C.3
  • 65
    • 0037092444 scopus 로고    scopus 로고
    • A developmental switch of AMPA receptor subunits in neocortical pyramidal neurons
    • Kumar S.S., Bacci A., Kharazia V., et al. A developmental switch of AMPA receptor subunits in neocortical pyramidal neurons. J Neurosci 22 8 (2002) 3005-3015
    • (2002) J Neurosci , vol.22 , Issue.8 , pp. 3005-3015
    • Kumar, S.S.1    Bacci, A.2    Kharazia, V.3
  • 66
    • 33744940044 scopus 로고    scopus 로고
    • Developmental regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid receptor subunit expression in forebrain and relationship to regional susceptibility to hypoxic/ischemic injury. II. Human cerebral white matter and cortex
    • Talos D.M., Follett P.L., Folkerth R.D., et al. Developmental regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid receptor subunit expression in forebrain and relationship to regional susceptibility to hypoxic/ischemic injury. II. Human cerebral white matter and cortex. J Comp Neurol 497 1 (2006) 61-77
    • (2006) J Comp Neurol , vol.497 , Issue.1 , pp. 61-77
    • Talos, D.M.1    Follett, P.L.2    Folkerth, R.D.3
  • 67
    • 0003150278 scopus 로고    scopus 로고
    • An overview of the preclinical aspects of topiramate: pharmacology, pharmacokinetics, and mechanism of action
    • Shank R.P., Gardocki J.F., Streeter A.J., et al. An overview of the preclinical aspects of topiramate: pharmacology, pharmacokinetics, and mechanism of action. Epilepsia 41 Suppl 1 (2000) S3-S9
    • (2000) Epilepsia , vol.41 , Issue.SUPPL. 1
    • Shank, R.P.1    Gardocki, J.F.2    Streeter, A.J.3
  • 68
    • 3042692042 scopus 로고    scopus 로고
    • NBQX or topiramate treatment following perinatal hypoxia-induced seizures prevents later increases in seizure-induced neuronal injury
    • Koh S., Tibayan F.D., Simpson J., et al. NBQX or topiramate treatment following perinatal hypoxia-induced seizures prevents later increases in seizure-induced neuronal injury. Epilepsia 45 6 (2004) 569-575
    • (2004) Epilepsia , vol.45 , Issue.6 , pp. 569-575
    • Koh, S.1    Tibayan, F.D.2    Simpson, J.3
  • 69
    • 0034854281 scopus 로고    scopus 로고
    • Topiramate blocks perinatal hypoxia- induced seizures in rat pups
    • Koh S., and Jensen F. Topiramate blocks perinatal hypoxia- induced seizures in rat pups. Ann Neurol 50 3 (2001) 366-372
    • (2001) Ann Neurol , vol.50 , Issue.3 , pp. 366-372
    • Koh, S.1    Jensen, F.2
  • 70
    • 2542527103 scopus 로고    scopus 로고
    • Topiramate extends the therapeutic window for hypothermia-mediated neuroprotection after stroke in neonatal rats
    • Liu Y., Barks J.D., Xu G., et al. Topiramate extends the therapeutic window for hypothermia-mediated neuroprotection after stroke in neonatal rats. Stroke 35 6 (2004) 1460-1465
    • (2004) Stroke , vol.35 , Issue.6 , pp. 1460-1465
    • Liu, Y.1    Barks, J.D.2    Xu, G.3
  • 71
    • 63049134585 scopus 로고    scopus 로고
    • Talampanel suppresses the acute and chronic effects of seizures in a rodent neonatal seizure model
    • Aujla P.K., Fetell M., and Jensen F.E. Talampanel suppresses the acute and chronic effects of seizures in a rodent neonatal seizure model. Epilepsia 50 4 (2009) 694-701
    • (2009) Epilepsia , vol.50 , Issue.4 , pp. 694-701
    • Aujla, P.K.1    Fetell, M.2    Jensen, F.E.3
  • 72
    • 0024551506 scopus 로고
    • Postnatal development of GABA-mediated synaptic inhibition in rat hippocampus
    • Swann J.W., Brady R.J., and Martin D.L. Postnatal development of GABA-mediated synaptic inhibition in rat hippocampus. Neuroscience 28 3 (1989) 551-561
    • (1989) Neuroscience , vol.28 , Issue.3 , pp. 551-561
    • Swann, J.W.1    Brady, R.J.2    Martin, D.L.3
  • 73
    • 0031892136 scopus 로고    scopus 로고
    • Developmental expression of GABA(A) receptor subunit mRNAs in individual hippocampal neurons in vitro and in vivo
    • Brooks-Kayal A., Jin H., Price M., et al. Developmental expression of GABA(A) receptor subunit mRNAs in individual hippocampal neurons in vitro and in vivo. J Neurochem 70 3 (1998) 1017-1028
    • (1998) J Neurochem , vol.70 , Issue.3 , pp. 1017-1028
    • Brooks-Kayal, A.1    Jin, H.2    Price, M.3
  • 74
    • 0032986707 scopus 로고    scopus 로고
    • Postnatal development of hippocampal dentate granule cell γ-aminobutyric acid A receptor pharmacological properties
    • Kapur J., and Macdonald R.L. Postnatal development of hippocampal dentate granule cell γ-aminobutyric acid A receptor pharmacological properties. Mol Pharmacol 55 (1999) 444-452
    • (1999) Mol Pharmacol , vol.55 , pp. 444-452
    • Kapur, J.1    Macdonald, R.L.2
  • 75
    • 0029164633 scopus 로고
    • NBQX blocks the acute and late epileptogenic effects of perinatal hypoxia
    • Jensen F.E., Alvarado S., Firkusny I.R., et al. NBQX blocks the acute and late epileptogenic effects of perinatal hypoxia. Epilepsia 36 10 (1995) 966-972
    • (1995) Epilepsia , vol.36 , Issue.10 , pp. 966-972
    • Jensen, F.E.1    Alvarado, S.2    Firkusny, I.R.3
  • 77
    • 0037336841 scopus 로고    scopus 로고
    • Excitatory actions of endogenously released GABA contribute to initiation of ictal epileptiform activity in the developing hippocampus
    • Dzhala V.I., and Staley K.J. Excitatory actions of endogenously released GABA contribute to initiation of ictal epileptiform activity in the developing hippocampus. J Neurosci 23 5 (2003) 1840-1846
    • (2003) J Neurosci , vol.23 , Issue.5 , pp. 1840-1846
    • Dzhala, V.I.1    Staley, K.J.2
  • 78
    • 1242272901 scopus 로고    scopus 로고
    • Developmental changes in GABAergic actions and seizure susceptibility in the rat hippocampus
    • Khazipov R., Khalilov I., Tyzio R., et al. Developmental changes in GABAergic actions and seizure susceptibility in the rat hippocampus. Eur J Neurosci 19 3 (2004) 590-600
    • (2004) Eur J Neurosci , vol.19 , Issue.3 , pp. 590-600
    • Khazipov, R.1    Khalilov, I.2    Tyzio, R.3
  • 79
    • 0029618270 scopus 로고
    • GABA and glutamate depolarize cortical progenitor cells and inhibit DNA synthesis
    • Loturco J.J., Owens D.F., Heath M.J., et al. GABA and glutamate depolarize cortical progenitor cells and inhibit DNA synthesis. Neuron 15 6 (1995) 1287-1298
    • (1995) Neuron , vol.15 , Issue.6 , pp. 1287-1298
    • Loturco, J.J.1    Owens, D.F.2    Heath, M.J.3
  • 80
    • 0029794366 scopus 로고    scopus 로고
    • Excitatory GABA responses in embryonic and neonatal cortical slices demonstrated by gramicidin perforated-patch recordings and calcium imaging
    • Owens D.F., Boyce L.H., Davis M.B., et al. Excitatory GABA responses in embryonic and neonatal cortical slices demonstrated by gramicidin perforated-patch recordings and calcium imaging. J Neurosci 16 20 (1996) 6414-6423
    • (1996) J Neurosci , vol.16 , Issue.20 , pp. 6414-6423
    • Owens, D.F.1    Boyce, L.H.2    Davis, M.B.3
  • 81
    • 30744467689 scopus 로고    scopus 로고
    • NKCC1 transporter facilitates seizures in the developing brain
    • Dzhala V.I., Talos D.M., Sdrulla D.A., et al. NKCC1 transporter facilitates seizures in the developing brain. Nat Med 11 11 (2005) 1205-1213
    • (2005) Nat Med , vol.11 , Issue.11 , pp. 1205-1213
    • Dzhala, V.I.1    Talos, D.M.2    Sdrulla, D.A.3
  • 82
    • 40449086100 scopus 로고    scopus 로고
    • Bumetanide enhances phenobarbital efficacy in a neonatal seizure model
    • Dzhala V.I., Brumback A.C., and Staley K.J. Bumetanide enhances phenobarbital efficacy in a neonatal seizure model. Ann Neurol 63 2 (2008) 222-235
    • (2008) Ann Neurol , vol.63 , Issue.2 , pp. 222-235
    • Dzhala, V.I.1    Brumback, A.C.2    Staley, K.J.3
  • 83
    • 0037386988 scopus 로고    scopus 로고
    • M-channels: neurological diseases, neuromodulation, and drug development
    • Cooper E.C., and Jan L.Y. M-channels: neurological diseases, neuromodulation, and drug development. Arch Neurol 60 4 (2003) 496-500
    • (2003) Arch Neurol , vol.60 , Issue.4 , pp. 496-500
    • Cooper, E.C.1    Jan, L.Y.2
  • 84
    • 2442641611 scopus 로고    scopus 로고
    • KCNQ/M channels control spike afterdepolarization and burst generation in hippocampal neurons
    • Yue C., and Yaari Y. KCNQ/M channels control spike afterdepolarization and burst generation in hippocampal neurons. J Neurosci 24 19 (2004) 4614-4624
    • (2004) J Neurosci , vol.24 , Issue.19 , pp. 4614-4624
    • Yue, C.1    Yaari, Y.2
  • 85
    • 0029871264 scopus 로고    scopus 로고
    • Queer current and pacemaker: the hyperpolarization-activated cation current in neurons
    • Pape H.C. Queer current and pacemaker: the hyperpolarization-activated cation current in neurons. Annu Rev Physiol 58 (1996) 299-327
    • (1996) Annu Rev Physiol , vol.58 , pp. 299-327
    • Pape, H.C.1
  • 86
    • 0035980469 scopus 로고    scopus 로고
    • Differential and age-dependent expression of hyperpolarization-activated, cyclic nucleotide-gated cation channel isoforms 1-4 suggests evolving roles in the developing rat hippocampus
    • Bender R.A., Brewster A., Santoro B., et al. Differential and age-dependent expression of hyperpolarization-activated, cyclic nucleotide-gated cation channel isoforms 1-4 suggests evolving roles in the developing rat hippocampus. Neuroscience 106 4 (2001) 689-698
    • (2001) Neuroscience , vol.106 , Issue.4 , pp. 689-698
    • Bender, R.A.1    Brewster, A.2    Santoro, B.3
  • 87
    • 28644452691 scopus 로고    scopus 로고
    • Synchronized network activity in developing rat hippocampus involves regional hyperpolarization-activated cyclic nucleotide-gated (HCN) channel function
    • Bender R.A., Galindo R., Mameli M., et al. Synchronized network activity in developing rat hippocampus involves regional hyperpolarization-activated cyclic nucleotide-gated (HCN) channel function. Eur J Neurosci 22 10 (2005) 2669-2674
    • (2005) Eur J Neurosci , vol.22 , Issue.10 , pp. 2669-2674
    • Bender, R.A.1    Galindo, R.2    Mameli, M.3
  • 88
    • 0034001913 scopus 로고    scopus 로고
    • Developmental changes in calcium channel types mediating central synaptic transmission
    • Iwasaki S., Momiyama A., Uchitel O.D., et al. Developmental changes in calcium channel types mediating central synaptic transmission. J Neurosci 20 1 (2000) 59-65
    • (2000) J Neurosci , vol.20 , Issue.1 , pp. 59-65
    • Iwasaki, S.1    Momiyama, A.2    Uchitel, O.D.3
  • 89
    • 0042357395 scopus 로고    scopus 로고
    • The biology of epilepsy genes
    • Noebels J.L. The biology of epilepsy genes. Annu Rev Neurosci 26 (2003) 599-625
    • (2003) Annu Rev Neurosci , vol.26 , pp. 599-625
    • Noebels, J.L.1
  • 90
    • 0041343159 scopus 로고    scopus 로고
    • Association between genetic variation of CACNA1H and childhood absence epilepsy
    • Chen Y., Lu J., Pan H., et al. Association between genetic variation of CACNA1H and childhood absence epilepsy. Ann Neurol 54 2 (2003) 239-243
    • (2003) Ann Neurol , vol.54 , Issue.2 , pp. 239-243
    • Chen, Y.1    Lu, J.2    Pan, H.3
  • 91
    • 0032212674 scopus 로고    scopus 로고
    • Neuropeptide-mediated excitability: a key triggering mechanism for seizure generation in the developing brain
    • Baram T.Z., and Hatalski C.G. Neuropeptide-mediated excitability: a key triggering mechanism for seizure generation in the developing brain. Trends Neurosci 21 11 (1998) 471-476
    • (1998) Trends Neurosci , vol.21 , Issue.11 , pp. 471-476
    • Baram, T.Z.1    Hatalski, C.G.2
  • 92
    • 0038166242 scopus 로고    scopus 로고
    • Increased activity of cyclooxygenase-2 signals early neurodegenerative events in the rat retina following transient ischemia
    • Ju W.K., Kim K.Y., and Neufeld A.H. Increased activity of cyclooxygenase-2 signals early neurodegenerative events in the rat retina following transient ischemia. Exp Eye Res 77 2 (2003) 137-145
    • (2003) Exp Eye Res , vol.77 , Issue.2 , pp. 137-145
    • Ju, W.K.1    Kim, K.Y.2    Neufeld, A.H.3
  • 93
    • 0035902478 scopus 로고    scopus 로고
    • Long-term, progressive hippocampal cell loss and dysfunction induced by early-life administration of corticotropin-releasing hormone reproduce the effects of early-life stress
    • Brunson K.L., Eghbal-Ahmadi M., Bender R., et al. Long-term, progressive hippocampal cell loss and dysfunction induced by early-life administration of corticotropin-releasing hormone reproduce the effects of early-life stress. Proc Natl Acad Sci U S A 98 15 (2001) 8856-8861
    • (2001) Proc Natl Acad Sci U S A , vol.98 , Issue.15 , pp. 8856-8861
    • Brunson, K.L.1    Eghbal-Ahmadi, M.2    Bender, R.3
  • 94
    • 0035094278 scopus 로고    scopus 로고
    • Corticotropin (ACTH) acts directly on amygdala neurons to down-regulate corticotropin-releasing hormone gene expression
    • Brunson K.L., Khan N., Eghbal-Ahmadi M., et al. Corticotropin (ACTH) acts directly on amygdala neurons to down-regulate corticotropin-releasing hormone gene expression. Ann Neurol 49 3 (2001) 304-312
    • (2001) Ann Neurol , vol.49 , Issue.3 , pp. 304-312
    • Brunson, K.L.1    Khan, N.2    Eghbal-Ahmadi, M.3
  • 95
    • 0030046685 scopus 로고    scopus 로고
    • Hypoxic-ischemic brain injury induces an acute microglial reaction in perinatal rats
    • Ivacko J.A., Sun R., and Silverstein F.S. Hypoxic-ischemic brain injury induces an acute microglial reaction in perinatal rats. Pediatr Res 39 1 (1996) 39-47
    • (1996) Pediatr Res , vol.39 , Issue.1 , pp. 39-47
    • Ivacko, J.A.1    Sun, R.2    Silverstein, F.S.3
  • 96
    • 1642321822 scopus 로고    scopus 로고
    • Early microglial activation following neonatal excitotoxic brain damage in mice: a potential target for neuroprotection
    • Dommergues M.A., Plaisant F., Verney C., et al. Early microglial activation following neonatal excitotoxic brain damage in mice: a potential target for neuroprotection. Neuroscience 121 3 (2003) 619-628
    • (2003) Neuroscience , vol.121 , Issue.3 , pp. 619-628
    • Dommergues, M.A.1    Plaisant, F.2    Verney, C.3
  • 97
    • 1642379743 scopus 로고    scopus 로고
    • Patterns of cerebral inflammatory response in a rabbit model of intrauterine infection-mediated brain lesion
    • Debillon T., Gras-Leguen C., Leroy S., et al. Patterns of cerebral inflammatory response in a rabbit model of intrauterine infection-mediated brain lesion. Brain Res Dev Brain Res 145 1 (2003) 39-48
    • (2003) Brain Res Dev Brain Res , vol.145 , Issue.1 , pp. 39-48
    • Debillon, T.1    Gras-Leguen, C.2    Leroy, S.3
  • 98
    • 0035079119 scopus 로고    scopus 로고
    • Inflammatory mediators and neonatal brain damage
    • Saliba E., and Henrot A. Inflammatory mediators and neonatal brain damage. Biol Neonate 79 3-4 (2001) 224-227
    • (2001) Biol Neonate , vol.79 , Issue.3-4 , pp. 224-227
    • Saliba, E.1    Henrot, A.2
  • 99
    • 33744740398 scopus 로고    scopus 로고
    • Development of microglia in the cerebral white matter of the human fetus and infant
    • Billiards S.S., Haynes R.L., Folkerth R.D., et al. Development of microglia in the cerebral white matter of the human fetus and infant. J Comp Neurol 497 2 (2006) 199-208
    • (2006) J Comp Neurol , vol.497 , Issue.2 , pp. 199-208
    • Billiards, S.S.1    Haynes, R.L.2    Folkerth, R.D.3
  • 100
    • 0035871840 scopus 로고    scopus 로고
    • Minocycline, a tetracycline derivative, is neuroprotective against excitotoxicity by inhibiting activation and proliferation of microglia
    • Tikka T., Fiebich B.L., Goldsteins G., et al. Minocycline, a tetracycline derivative, is neuroprotective against excitotoxicity by inhibiting activation and proliferation of microglia. J Neurosci 21 8 (2001) 2580-2588
    • (2001) J Neurosci , vol.21 , Issue.8 , pp. 2580-2588
    • Tikka, T.1    Fiebich, B.L.2    Goldsteins, G.3
  • 101
    • 38449102377 scopus 로고    scopus 로고
    • Rapid astrocyte and microglial activation following pilocarpine-induced seizures in rats
    • Shapiro L.A., Wang L., and Ribak C.E. Rapid astrocyte and microglial activation following pilocarpine-induced seizures in rats. Epilepsia 49 Suppl 2 (2008) 33-41
    • (2008) Epilepsia , vol.49 , Issue.SUPPL. 2 , pp. 33-41
    • Shapiro, L.A.1    Wang, L.2    Ribak, C.E.3
  • 102
    • 46049103354 scopus 로고    scopus 로고
    • The role of cytokines in the pathophysiology of epilepsy
    • Vezzani A., Balosso S., and Ravizza T. The role of cytokines in the pathophysiology of epilepsy. Brain Behav Immun 22 6 (2008) 797-803
    • (2008) Brain Behav Immun , vol.22 , Issue.6 , pp. 797-803
    • Vezzani, A.1    Balosso, S.2    Ravizza, T.3
  • 103
    • 0037474650 scopus 로고    scopus 로고
    • Dynamics of microglia in the developing rat brain
    • Dalmau I., Vela J.M., Gonzalez B., et al. Dynamics of microglia in the developing rat brain. J Comp Neurol 458 2 (2003) 144-157
    • (2003) J Comp Neurol , vol.458 , Issue.2 , pp. 144-157
    • Dalmau, I.1    Vela, J.M.2    Gonzalez, B.3
  • 104
    • 0030773837 scopus 로고    scopus 로고
    • Synaptic efficacy enhanced by glial cells in vitro
    • Pfrieger F.W., and Barres B.A. Synaptic efficacy enhanced by glial cells in vitro. Science 277 5332 (1997) 1684-1687
    • (1997) Science , vol.277 , Issue.5332 , pp. 1684-1687
    • Pfrieger, F.W.1    Barres, B.A.2
  • 105
    • 36849076770 scopus 로고    scopus 로고
    • The classical complement cascade mediates CNS synapse elimination
    • Stevens B., Allen N.J., Vazquez L.E., et al. The classical complement cascade mediates CNS synapse elimination. Cell 131 6 (2007) 1164-1178
    • (2007) Cell , vol.131 , Issue.6 , pp. 1164-1178
    • Stevens, B.1    Allen, N.J.2    Vazquez, L.E.3
  • 106
    • 33646382411 scopus 로고    scopus 로고
    • Minocycline inhibits caspase-dependent and -independent cell death pathways and is neuroprotective against hippocampal damage after treatment with kainic acid in mice
    • Heo K., Cho Y.J., Cho K.J., et al. Minocycline inhibits caspase-dependent and -independent cell death pathways and is neuroprotective against hippocampal damage after treatment with kainic acid in mice. Neurosci Lett 398 3 (2006) 195-200
    • (2006) Neurosci Lett , vol.398 , Issue.3 , pp. 195-200
    • Heo, K.1    Cho, Y.J.2    Cho, K.J.3
  • 107
    • 70350005202 scopus 로고    scopus 로고
    • Minocycline treatment following hypoxic/ischaemic injury attenuates white matter injury in a rodent model of periventricular leucomalacia
    • Lechpammer M., Manning S.M., Samonte F., et al. Minocycline treatment following hypoxic/ischaemic injury attenuates white matter injury in a rodent model of periventricular leucomalacia. Neuropathol Appl Neurobiol 34 4 (2008) 379-393
    • (2008) Neuropathol Appl Neurobiol , vol.34 , Issue.4 , pp. 379-393
    • Lechpammer, M.1    Manning, S.M.2    Samonte, F.3
  • 108
    • 14644437067 scopus 로고    scopus 로고
    • Doxycycline reduces cleaved caspase-3 and microglial activation in an animal model of neonatal hypoxia-ischemia
    • Jantzie L.L., Cheung P.Y., and Todd K.G. Doxycycline reduces cleaved caspase-3 and microglial activation in an animal model of neonatal hypoxia-ischemia. J Cereb Blood Flow Metab 25 3 (2005) 314-324
    • (2005) J Cereb Blood Flow Metab , vol.25 , Issue.3 , pp. 314-324
    • Jantzie, L.L.1    Cheung, P.Y.2    Todd, K.G.3
  • 109
    • 18744400217 scopus 로고    scopus 로고
    • Seizure-induced neuronal death in the immature brain
    • Wasterlain C.G., Niquet J., Thompson K.W., et al. Seizure-induced neuronal death in the immature brain. Prog Brain Res 135 (2002) 335-353
    • (2002) Prog Brain Res , vol.135 , pp. 335-353
    • Wasterlain, C.G.1    Niquet, J.2    Thompson, K.W.3
  • 110
    • 57749089871 scopus 로고    scopus 로고
    • Delayed neural network degeneration after neonatal hypoxia-ischemia
    • Stone B.S., Zhang J., Mack D.W., et al. Delayed neural network degeneration after neonatal hypoxia-ischemia. Ann Neurol 64 5 (2008) 535-546
    • (2008) Ann Neurol , vol.64 , Issue.5 , pp. 535-546
    • Stone, B.S.1    Zhang, J.2    Mack, D.W.3
  • 112
    • 0033539567 scopus 로고    scopus 로고
    • Subplate neuron ablation alters neurotrophin expression and ocular dominance column formation
    • Lein E.S., Finney E.M., McQuillen P.S., et al. Subplate neuron ablation alters neurotrophin expression and ocular dominance column formation. Proc Natl Acad Sci U S A 96 23 (1999) 13491-13495
    • (1999) Proc Natl Acad Sci U S A , vol.96 , Issue.23 , pp. 13491-13495
    • Lein, E.S.1    Finney, E.M.2    McQuillen, P.S.3
  • 113
    • 0041843767 scopus 로고    scopus 로고
    • Role of subplate neurons in functional maturation of visual cortical columns
    • Kanold P.O., Kara P., Reid R.C., et al. Role of subplate neurons in functional maturation of visual cortical columns. Science 301 5632 (2003) 521-525
    • (2003) Science , vol.301 , Issue.5632 , pp. 521-525
    • Kanold, P.O.1    Kara, P.2    Reid, R.C.3
  • 114
    • 0038673168 scopus 로고    scopus 로고
    • Selective vulnerability of subplate neurons after early neonatal hypoxia-ischemia
    • McQuillen P.S., Sheldon R.A., Shatz C.J., et al. Selective vulnerability of subplate neurons after early neonatal hypoxia-ischemia. J Neurosci 23 8 (2003) 3308-3315
    • (2003) J Neurosci , vol.23 , Issue.8 , pp. 3308-3315
    • McQuillen, P.S.1    Sheldon, R.A.2    Shatz, C.J.3
  • 115
    • 17844393791 scopus 로고    scopus 로고
    • Erythropoietin improves functional and histological outcome in neonatal stroke
    • Chang Y.S., Mu D., Wendland M., et al. Erythropoietin improves functional and histological outcome in neonatal stroke. Pediatr Res 58 1 (2005) 106-111
    • (2005) Pediatr Res , vol.58 , Issue.1 , pp. 106-111
    • Chang, Y.S.1    Mu, D.2    Wendland, M.3
  • 116
    • 34548295610 scopus 로고    scopus 로고
    • Erythropoietin enhances long-term neuroprotection and neurogenesis in neonatal stroke
    • Gonzalez F.F., McQuillen P., Mu D., et al. Erythropoietin enhances long-term neuroprotection and neurogenesis in neonatal stroke. Dev Neurosci 29 4-5 (2007) 321-330
    • (2007) Dev Neurosci , vol.29 , Issue.4-5 , pp. 321-330
    • Gonzalez, F.F.1    McQuillen, P.2    Mu, D.3
  • 117
    • 33846247068 scopus 로고    scopus 로고
    • Effects of a single dose of erythropoietin on subsequent seizure susceptibility in rats exposed to acute hypoxia at P10
    • Mikati M.A., El Hokayem J.A., and El Sabban M.E. Effects of a single dose of erythropoietin on subsequent seizure susceptibility in rats exposed to acute hypoxia at P10. Epilepsia 48 1 (2007) 175-181
    • (2007) Epilepsia , vol.48 , Issue.1 , pp. 175-181
    • Mikati, M.A.1    El Hokayem, J.A.2    El Sabban, M.E.3
  • 118
    • 33750684965 scopus 로고    scopus 로고
    • Effects of seizures on developmental processes in the immature brain
    • Ben Ari Y., and Holmes G.L. Effects of seizures on developmental processes in the immature brain. Lancet Neurol 5 12 (2006) 1055-1063
    • (2006) Lancet Neurol , vol.5 , Issue.12 , pp. 1055-1063
    • Ben Ari, Y.1    Holmes, G.L.2
  • 119
    • 10644239897 scopus 로고    scopus 로고
    • Seizures in the developing brain cause adverse long-term effects on spatial learning and anxiety
    • Sayin U., Sutula T.P., and Stafstrom C.E. Seizures in the developing brain cause adverse long-term effects on spatial learning and anxiety. Epilepsia 45 12 (2004) 1539-1548
    • (2004) Epilepsia , vol.45 , Issue.12 , pp. 1539-1548
    • Sayin, U.1    Sutula, T.P.2    Stafstrom, C.E.3
  • 121
    • 41349083085 scopus 로고    scopus 로고
    • The age of plasticity: developmental regulation of synaptic plasticity in neocortical microcircuits
    • Maffei A., and Turrigiano G. The age of plasticity: developmental regulation of synaptic plasticity in neocortical microcircuits. Prog Brain Res 169 (2008) 211-223
    • (2008) Prog Brain Res , vol.169 , pp. 211-223
    • Maffei, A.1    Turrigiano, G.2
  • 122
    • 51149094794 scopus 로고    scopus 로고
    • Early alterations of AMPA receptors mediate synaptic potentiation induced by neonatal seizures
    • Rakhade S.N., Zhou C., Aujla P.K., et al. Early alterations of AMPA receptors mediate synaptic potentiation induced by neonatal seizures. J Neurosci 28 32 (2008) 7979-7990
    • (2008) J Neurosci , vol.28 , Issue.32 , pp. 7979-7990
    • Rakhade, S.N.1    Zhou, C.2    Aujla, P.K.3
  • 123
    • 34249945513 scopus 로고    scopus 로고
    • A single episode of neonatal seizures permanently alters glutamatergic synapses
    • Cornejo B.J., Mesches M.H., Coultrap S., et al. A single episode of neonatal seizures permanently alters glutamatergic synapses. Ann Neurol 61 5 (2007) 411-426
    • (2007) Ann Neurol , vol.61 , Issue.5 , pp. 411-426
    • Cornejo, B.J.1    Mesches, M.H.2    Coultrap, S.3
  • 124
    • 33746894171 scopus 로고    scopus 로고
    • Models of pediatric epilepsies: strategies and opportunities
    • Stafstrom C.E., Moshe S.L., Swann J.W., et al. Models of pediatric epilepsies: strategies and opportunities. Epilepsia 47 8 (2006) 1407-1414
    • (2006) Epilepsia , vol.47 , Issue.8 , pp. 1407-1414
    • Stafstrom, C.E.1    Moshe, S.L.2    Swann, J.W.3
  • 125
    • 16344396100 scopus 로고    scopus 로고
    • AMPA/kainate receptor-mediated downregulation of GABAergic synaptic transmission by calcineurin after seizures in the developing rat brain
    • Sanchez R.M., Dai W., Levada R.E., et al. AMPA/kainate receptor-mediated downregulation of GABAergic synaptic transmission by calcineurin after seizures in the developing rat brain. J Neurosci 25 13 (2005) 3442-3451
    • (2005) J Neurosci , vol.25 , Issue.13 , pp. 3442-3451
    • Sanchez, R.M.1    Dai, W.2    Levada, R.E.3
  • 126
    • 33750941236 scopus 로고    scopus 로고
    • Enhancing GABA(A) receptor alpha 1 subunit levels in hippocampal dentate gyrus inhibits epilepsy development in an animal model of temporal lobe epilepsy
    • Raol Y.H., Lund I.V., Bandyopadhyay S., et al. Enhancing GABA(A) receptor alpha 1 subunit levels in hippocampal dentate gyrus inhibits epilepsy development in an animal model of temporal lobe epilepsy. J Neurosci 26 44 (2006) 11342-11346
    • (2006) J Neurosci , vol.26 , Issue.44 , pp. 11342-11346
    • Raol, Y.H.1    Lund, I.V.2    Bandyopadhyay, S.3
  • 127
    • 33645100228 scopus 로고    scopus 로고
    • Selective impairment of GABAergic synaptic transmission in the flurothyl model of neonatal seizures
    • Isaeva E., Isaev D., Khazipov R., et al. Selective impairment of GABAergic synaptic transmission in the flurothyl model of neonatal seizures. Eur J Neurosci 23 6 (2006) 1559-1566
    • (2006) Eur J Neurosci , vol.23 , Issue.6 , pp. 1559-1566
    • Isaeva, E.1    Isaev, D.2    Khazipov, R.3
  • 128
    • 0019459136 scopus 로고
    • Adverse effects of phenobarbital on morphological and biochemical development of fetal mouse spinal cord neurons in culture
    • Bergey G.K., Swaiman K.F., Schrier B.K., et al. Adverse effects of phenobarbital on morphological and biochemical development of fetal mouse spinal cord neurons in culture. Ann Neurol 9 6 (1981) 584-589
    • (1981) Ann Neurol , vol.9 , Issue.6 , pp. 584-589
    • Bergey, G.K.1    Swaiman, K.F.2    Schrier, B.K.3
  • 129
    • 0023733767 scopus 로고
    • Effects of chronic phenobarbital exposure on cultured mouse spinal cord neurons
    • Serrano E.E., Kunis D.M., and Ransom B.R. Effects of chronic phenobarbital exposure on cultured mouse spinal cord neurons. Ann Neurol 24 3 (1988) 429-438
    • (1988) Ann Neurol , vol.24 , Issue.3 , pp. 429-438
    • Serrano, E.E.1    Kunis, D.M.2    Ransom, B.R.3
  • 130
    • 0025364314 scopus 로고
    • Influence of early neonatal phenobarbital exposure on cerebral energy metabolism and behavior
    • Pereira de Vasconcelos A., Colin C., Desor D., et al. Influence of early neonatal phenobarbital exposure on cerebral energy metabolism and behavior. Exp Neurol 108 2 (1990) 176-187
    • (1990) Exp Neurol , vol.108 , Issue.2 , pp. 176-187
    • Pereira de Vasconcelos, A.1    Colin, C.2    Desor, D.3
  • 131
    • 0028959844 scopus 로고
    • Behavioral and metabolic consequences of neonatal exposure to diazepam in rat pups
    • Schroeder H., Humbert A.C., Koziel V., et al. Behavioral and metabolic consequences of neonatal exposure to diazepam in rat pups. Exp Neurol 131 1 (1995) 53-63
    • (1995) Exp Neurol , vol.131 , Issue.1 , pp. 53-63
    • Schroeder, H.1    Humbert, A.C.2    Koziel, V.3
  • 132
    • 0037069448 scopus 로고    scopus 로고
    • Antiepileptic drugs and apoptotic neurodegeneration in the developing brain
    • Bittigau P., Sifringer M., Genz K., et al. Antiepileptic drugs and apoptotic neurodegeneration in the developing brain. Proc Natl Acad Sci U S A 99 23 (2002) 15089-15094
    • (2002) Proc Natl Acad Sci U S A , vol.99 , Issue.23 , pp. 15089-15094
    • Bittigau, P.1    Sifringer, M.2    Genz, K.3
  • 133
    • 2342548181 scopus 로고    scopus 로고
    • Therapeutic doses of topiramate are not toxic to the developing rat brain
    • Glier C., Dzietko M., Bittigau P., et al. Therapeutic doses of topiramate are not toxic to the developing rat brain. Exp Neurol 187 2 (2004) 403-409
    • (2004) Exp Neurol , vol.187 , Issue.2 , pp. 403-409
    • Glier, C.1    Dzietko, M.2    Bittigau, P.3
  • 134
    • 18144398574 scopus 로고    scopus 로고
    • Sulthiame but not levetiracetam exerts neurotoxic effect in the developing rat brain
    • Manthey D., Asimiadou S., Stefovska V., et al. Sulthiame but not levetiracetam exerts neurotoxic effect in the developing rat brain. Exp Neurol 193 2 (2005) 497-503
    • (2005) Exp Neurol , vol.193 , Issue.2 , pp. 497-503
    • Manthey, D.1    Asimiadou, S.2    Stefovska, V.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.