메뉴 건너뛰기




Volumn 4, Issue 11, 2009, Pages

Persistence criteria for susceptibility genes for schizophrenia: A discussion from an evolutionary viewpoint

Author keywords

[No Author keywords available]

Indexed keywords

CELL NUCLEUS DNA; MITOCHONDRIAL DNA;

EID: 70450195005     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0007799     Document Type: Article
Times cited : (21)

References (68)
  • 1
    • 0034660559 scopus 로고    scopus 로고
    • Searching for genetic determinants in the new millennium
    • Risch NJ (2000) Searching for genetic determinants in the new millennium. Nature 405: 847-856.
    • (2000) Nature , vol.405 , pp. 847-856
    • Risch, N.J.1
  • 2
    • 46449113977 scopus 로고    scopus 로고
    • Schizophrenia, "just the facts" what we know in 2008. 2. Epidemiology and etiology
    • Tandon R, Keshavan MS, Nasrallah HA (2008) Schizophrenia, "just the facts" what we know in 2008. 2. Epidemiology and etiology. Schizophr Res 102: 1-18.
    • (2008) Schizophr Res , vol.102 , pp. 1-18
    • Tandon, R.1    Keshavan, M.S.2    Nasrallah, H.A.3
  • 3
    • 0000632896 scopus 로고
    • Schizophrenia: The Epidemiological Horizon
    • Hirsch SR, Weinberger DR, eds, London: Blackwell Science. pp
    • Jablensky AV (1995) Schizophrenia: the Epidemiological Horizon. In: Hirsch SR, Weinberger DR, eds. Schizophrenia. London: Blackwell Science. pp 206-252.
    • (1995) Schizophrenia , pp. 206-252
    • Jablensky, A.V.1
  • 4
    • 0026056611 scopus 로고
    • Changes in the administrative incidence of schizophrenia
    • Harrison G, Cooper JE, Gancarczyk R (1991) Changes in the administrative incidence of schizophrenia. Br J Psychiatry 159: 811-816.
    • (1991) Br J Psychiatry , vol.159 , pp. 811-816
    • Harrison, G.1    Cooper, J.E.2    Gancarczyk, R.3
  • 5
    • 0035280633 scopus 로고    scopus 로고
    • Time trends in first admissions for schizophrenia and paranoid psychosis in Stockholm County, Sweden
    • Osby U, Hammer N, Brandt L, Wicks S, Thinsz Z, et al. (2001) Time trends in first admissions for schizophrenia and paranoid psychosis in Stockholm County, Sweden. Schizophr Res 47: 247-254.
    • (2001) Schizophr Res , vol.47 , pp. 247-254
    • Osby, U.1    Hammer, N.2    Brandt, L.3    Wicks, S.4    Thinsz, Z.5
  • 6
    • 8244257694 scopus 로고
    • Untersuchungen über die Fruchtbarkeit gewisser Gruppen von Geisteskranken.
    • Essen-Möller E (1935) Untersuchungen über die Fruchtbarkeit gewisser Gruppen von Geisteskranken. Acta Psychiatr Neurol 8: 1-314.
    • (1935) Acta Psychiatr Neurol , vol.8 , pp. 1-314
    • Essen-Möller, E.1
  • 7
    • 84965139584 scopus 로고
    • A genetic and neuropsychiatric investigation of a North-Swedish population
    • Böök JA (1953) A genetic and neuropsychiatric investigation of a North-Swedish population. Acta Genet et Stat Med 4: 1-100.
    • (1953) Acta Genet et Stat Med , vol.4 , pp. 1-100
    • Böök, J.A.1
  • 8
    • 0015118172 scopus 로고
    • Marriage and fertility of psychiatric patients compared with national data
    • Slater E, Hare H, Price J (1971) Marriage and fertility of psychiatric patients compared with national data. Soc Biol 18: S60-S73.
    • (1971) Soc Biol , vol.18
    • Slater, E.1    Hare, H.2    Price, J.3
  • 9
    • 0015901848 scopus 로고
    • Differential fertility in schizophrenia
    • Larson CA, Nyman GE (1973) Differential fertility in schizophrenia. Acta Psychiatr Scand 49: 272-280.
    • (1973) Acta Psychiatr Scand , vol.49 , pp. 272-280
    • Larson, C.A.1    Nyman, G.E.2
  • 10
    • 0018937527 scopus 로고
    • Fertility of psychiatric first admissions in Norway, 1936-1975
    • Ødegård Ø (1980) Fertility of psychiatric first admissions in Norway, 1936-1975. Acta Psychiatr Scand 62: 212-220.
    • (1980) Acta Psychiatr Scand , vol.62 , pp. 212-220
    • Ødegård, Ø.1
  • 11
    • 0020308160 scopus 로고
    • Is there an increase of reproductive rates in schizophrenics? I. Critical review of the literature
    • Haverkamp F, Propping P, Hilger T (1982) Is there an increase of reproductive rates in schizophrenics? I. Critical review of the literature. Arch Psychiatr Nervenkr 323: 439-450.
    • (1982) Arch Psychiatr Nervenkr , vol.323 , pp. 439-450
    • Haverkamp, F.1    Propping, P.2    Hilger, T.3
  • 12
    • 0027155273 scopus 로고
    • Reproductive rates in schizophrenic outpatients
    • Nanko S, Moridaira J (1993) Reproductive rates in schizophrenic outpatients. Acta Psychiatr Scand 87: 400-404.
    • (1993) Acta Psychiatr Scand , vol.87 , pp. 400-404
    • Nanko, S.1    Moridaira, J.2
  • 13
    • 0028957794 scopus 로고
    • Reproductive rates in families of schizophrenic patients in a case-control study
    • Fananas L, Bertranpetit J (1995) Reproductive rates in families of schizophrenic patients in a case-control study. Acta Psychiatr Scand 91: 202-204.
    • (1995) Acta Psychiatr Scand , vol.91 , pp. 202-204
    • Fananas, L.1    Bertranpetit, J.2
  • 15
    • 0031791141 scopus 로고    scopus 로고
    • Reduced fertility in schizophrenia: Here to stay?
    • Nimgaonkar VL (1998) Reduced fertility in schizophrenia: here to stay? Acta Psychiatr Scand 98: 348-353.
    • (1998) Acta Psychiatr Scand , vol.98 , pp. 348-353
    • Nimgaonkar, V.L.1
  • 17
    • 0037365627 scopus 로고    scopus 로고
    • Fertility of patients with schizophrenia, their siblings, and the general population: A cohort study from 1950 to 1959 in Finland
    • Haukka J, Suvisaari J, Lonnqvist J (2003) Fertility of patients with schizophrenia, their siblings, and the general population: a cohort study from 1950 to 1959 in Finland. Am J Psychiatry 160: 460-463.
    • (2003) Am J Psychiatry , vol.160 , pp. 460-463
    • Haukka, J.1    Suvisaari, J.2    Lonnqvist, J.3
  • 18
    • 0029554002 scopus 로고
    • A Darwinian approach to the origin of psychosis
    • Crow TJ (1995) A Darwinian approach to the origin of psychosis. Brit J Psychiatry 167: 12-25.
    • (1995) Brit J Psychiatry , vol.167 , pp. 12-25
    • Crow, T.J.1
  • 19
    • 1242298646 scopus 로고    scopus 로고
    • Schizophrenia - an evolutionary enigma?
    • Brüne M (2004) Schizophrenia - an evolutionary enigma? Neurosci Biobehav Rev 28: 41-53.
    • (2004) Neurosci Biobehav Rev , vol.28 , pp. 41-53
    • Brüne, M.1
  • 20
    • 33845516667 scopus 로고    scopus 로고
    • Resolving the paradox of common, harmful, heritable mental disorders: Which evolutionary genetic models work best?
    • Keller CK, Miller G (2006) Resolving the paradox of common, harmful, heritable mental disorders: Which evolutionary genetic models work best? Behav Brain Sci 29: 385-452.
    • (2006) Behav Brain Sci , vol.29 , pp. 385-452
    • Keller, C.K.1    Miller, G.2
  • 21
    • 0001005077 scopus 로고
    • Schizophrenia as a genetic morphism
    • Huxley J, Mayr E, Osmond H, Hoffer A (1964) Schizophrenia as a genetic morphism. Nature 204: 220-221.
    • (1964) Nature , vol.204 , pp. 220-221
    • Huxley, J.1    Mayr, E.2    Osmond, H.3    Hoffer, A.4
  • 22
    • 0016220948 scopus 로고
    • Inheritance of schizophrenia
    • Karlsson JL (1974) Inheritance of schizophrenia. Acta Psychiatr Scand 247 (Suppl): 77-88.
    • (1974) Acta Psychiatr Scand , vol.247 , Issue.SUPPL. , pp. 77-88
    • Karlsson, J.L.1
  • 24
    • 3142693330 scopus 로고    scopus 로고
    • Schizophrenia as one extreme of a sexually selected fitness indicator
    • Shaner A, Miller G, Mintz J (2004) Schizophrenia as one extreme of a sexually selected fitness indicator. Schizophr Res 70: 101-109.
    • (2004) Schizophr Res , vol.70 , pp. 101-109
    • Shaner, A.1    Miller, G.2    Mintz, J.3
  • 25
    • 0014721392 scopus 로고
    • A study of schizophrenia. A clinical, prognostic and family investigation
    • Lindelius R (1970) A study of schizophrenia. A clinical, prognostic and family investigation. Acta Psychiatr Scand Suppl 216.
    • (1970) Acta Psychiatr Scand , Issue.SUPPL. 216
    • Lindelius, R.1
  • 27
    • 0017167160 scopus 로고
    • Differential fertility of adopted schizophrenics and their half-siblings
    • Rimmer J, Jacobsen B (1976) Differential fertility of adopted schizophrenics and their half-siblings. Acta Psychiatr Scand 54: 161-166.
    • (1976) Acta Psychiatr Scand , vol.54 , pp. 161-166
    • Rimmer, J.1    Jacobsen, B.2
  • 28
    • 0002646706 scopus 로고
    • Fertility of psychotics: Demography
    • Cancro R, ed, New York: Brunner/Mazel
    • Erlenmeyer-Kimling L (1978) Fertility of psychotics: demography. In: Cancro R, ed. Annual Review of the Schizophrenic Syndrome. New York: Brunner/Mazel 5: 298-333.
    • (1978) Annual Review of the Schizophrenic Syndrome , vol.5 , pp. 298-333
    • Erlenmeyer-Kimling, L.1
  • 29
    • 33847262475 scopus 로고    scopus 로고
    • Fertility of first-degree relatives of patients with schizophrenia: A three generation perspective
    • Svensson AC, Lichtenstein P, Sandin S, Hultman CM (2007) Fertility of first-degree relatives of patients with schizophrenia: A three generation perspective. Schizophr res 91: 238-245.
    • (2007) Schizophr res , vol.91 , pp. 238-245
    • Svensson, A.C.1    Lichtenstein, P.2    Sandin, S.3    Hultman, C.M.4
  • 30
    • 46249104490 scopus 로고    scopus 로고
    • Systematic Meta-Analyses and Field Synopsis of Genetic Association Studies in Schizophrenia: The SZGene Database
    • Allen NC, Bagades S, McQueen MB, Ioannidis JPA, Kavvoura FK, et al. (2008) Systematic Meta-Analyses and Field Synopsis of Genetic Association Studies in Schizophrenia: The SZGene Database. Nat Genet 40: 827-834.
    • (2008) Nat Genet , vol.40 , pp. 827-834
    • Allen, N.C.1    Bagades, S.2    McQueen, M.B.3    Ioannidis, J.P.A.4    Kavvoura, F.K.5
  • 31
    • 68449096727 scopus 로고    scopus 로고
    • Shi J, Levinson DF, Duan J, Sanders AR, Zheng Y, et al. (2009) Common variants on 6p.22.1 are associated with schizophrenia. Nature (Published online 1 July 2009;doi:10.1038/nature08192).
    • Shi J, Levinson DF, Duan J, Sanders AR, Zheng Y, et al. (2009) Common variants on 6p.22.1 are associated with schizophrenia. Nature (Published online 1 July 2009;doi:10.1038/nature08192).
  • 32
    • 68449086236 scopus 로고    scopus 로고
    • The International Schizophrenia Consortium (2009) Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature (Published online 1 July 2009;doi:10.1038/nature08185).
    • The International Schizophrenia Consortium (2009) Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature (Published online 1 July 2009;doi:10.1038/nature08185).
  • 33
    • 61449229353 scopus 로고    scopus 로고
    • Need AC, Ge D, Weale ME, Maia J, Feng S, et al. (2009) A Genome-Wide Investigation of SNPs and CNVs in Schizophrenia. PLoS Genet 5(2): e1000373. doi:10.1371/journal.pgen.1000373.
    • Need AC, Ge D, Weale ME, Maia J, Feng S, et al. (2009) A Genome-Wide Investigation of SNPs and CNVs in Schizophrenia. PLoS Genet 5(2): e1000373. doi:10.1371/journal.pgen.1000373.
  • 34
    • 68449090594 scopus 로고    scopus 로고
    • Stefasson H, Ophoff RA, Steinberg S, Andreassen OA, Cichon S, et al. (2009) Common variants conferring risk of schizophrenia. Nature (Published online 1 July 2009;doi:10.1038/nature08186).
    • Stefasson H, Ophoff RA, Steinberg S, Andreassen OA, Cichon S, et al. (2009) Common variants conferring risk of schizophrenia. Nature (Published online 1 July 2009;doi:10.1038/nature08186).
  • 35
    • 0029805706 scopus 로고    scopus 로고
    • The new genomics: Global view of biology
    • Lander ES (1996) The new genomics: global view of biology. Science 274: 536-539.
    • (1996) Science , vol.274 , pp. 536-539
    • Lander, E.S.1
  • 36
    • 0035451780 scopus 로고    scopus 로고
    • On the allelic spectrum of human disease
    • Reich DE, Lander ES (2001) On the allelic spectrum of human disease. Trends Genet 17: 502-510.
    • (2001) Trends Genet , vol.17 , pp. 502-510
    • Reich, D.E.1    Lander, E.S.2
  • 37
    • 0034969437 scopus 로고    scopus 로고
    • Are rare variants responsible for susceptibility to complex diseases?
    • Pritchard JK (2001) Are rare variants responsible for susceptibility to complex diseases? Am J Hum Genet 69: 124-137.
    • (2001) Am J Hum Genet , vol.69 , pp. 124-137
    • Pritchard, J.K.1
  • 38
    • 0036799545 scopus 로고    scopus 로고
    • The allelic architecture of human disease genes: Common disease-common variant ... or not?
    • Pritchard JK, Cox NJ (2002) The allelic architecture of human disease genes: common disease-common variant ... or not? Hum Mol Genet 11: 2417-2433.
    • (2002) Hum Mol Genet , vol.11 , pp. 2417-2433
    • Pritchard, J.K.1    Cox, N.J.2
  • 39
    • 33646229252 scopus 로고    scopus 로고
    • identification of the semaphoring receptor PLXMA2 as a candidate for susceptibility to schizophrenia
    • Mah S, Nelson MR, DeLisi LE, Reneland RH, Markward N, et al. (2006) identification of the semaphoring receptor PLXMA2 as a candidate for susceptibility to schizophrenia. Mol Psychiatry 11: 471-478.
    • (2006) Mol Psychiatry , vol.11 , pp. 471-478
    • Mah, S.1    Nelson, M.R.2    DeLisi, L.E.3    Reneland, R.H.4    Markward, N.5
  • 40
    • 34249332776 scopus 로고    scopus 로고
    • Converging evidence for a pseudoautosomal cytokine receptor gene locus in schizophrenia
    • Lenz T, Morgan TV, Athanasiou M, Dain B, Reed CR, et al. (2007) Converging evidence for a pseudoautosomal cytokine receptor gene locus in schizophrenia. Mol Psychiatry 12: 572-580.
    • (2007) Mol Psychiatry , vol.12 , pp. 572-580
    • Lenz, T.1    Morgan, T.V.2    Athanasiou, M.3    Dain, B.4    Reed, C.R.5
  • 41
    • 67651180973 scopus 로고    scopus 로고
    • A genome-wide association study in 574 schizophrenia trios using DNA pooling
    • doi10.1038/mp.2008.33
    • Kirov G, Zaharieva I, Georgieva L, Moskvina V, Nikolov I, et al. (2008) A genome-wide association study in 574 schizophrenia trios using DNA pooling. Mol Psychiatry (doi10.1038/mp.2008.33).
    • (2008) Mol Psychiatry
    • Kirov, G.1    Zaharieva, I.2    Georgieva, L.3    Moskvina, V.4    Nikolov, I.5
  • 42
    • 40149105889 scopus 로고    scopus 로고
    • Genome-wide association identifies a common variant in the reelin gene that increases the risk of schizophrenia only in women
    • doi:10.1371/journal.pgen.0040028
    • Shifman S, Johannxsson M, Bronstein M, Chen SX, Collier DA, et al. (2008) Genome-wide association identifies a common variant in the reelin gene that increases the risk of schizophrenia only in women. PLoS Genet 4(2): e28. doi:10.1371/journal.pgen.0040028.
    • (2008) PLoS Genet , vol.4 , Issue.2
    • Shifman, S.1    Johannxsson, M.2    Bronstein, M.3    Chen, S.X.4    Collier, D.A.5
  • 44
    • 43949122950 scopus 로고    scopus 로고
    • Genomewide association study for schizophrenia in the CATIE study: Results of stage I
    • Sullivan PF, Lin D, Tzeng JY, van den Oord E, Perkin D, et al. (2008) Genomewide association study for schizophrenia in the CATIE study: results of stage I. Mol Psychiatry 13: 570-584.
    • (2008) Mol Psychiatry , vol.13 , pp. 570-584
    • Sullivan, P.F.1    Lin, D.2    Tzeng, J.Y.3    van den Oord, E.4    Perkin, D.5
  • 45
    • 43349097737 scopus 로고    scopus 로고
    • No significant association of 14 candidate genes with schizophrenia in a large European ancestry sample: Implication for psychiatric genetics
    • Sanders AR, Duan J, Levinson DF, Shi J, He D, et al. (2008) No significant association of 14 candidate genes with schizophrenia in a large European ancestry sample: implication for psychiatric genetics. Am J Psychiatry 165: 497-506.
    • (2008) Am J Psychiatry , vol.165 , pp. 497-506
    • Sanders, A.R.1    Duan, J.2    Levinson, D.F.3    Shi, J.4    He, D.5
  • 47
    • 38349106160 scopus 로고    scopus 로고
    • Comparative genome hybridization suggests a role for NRXN1 and APBA2 in schizophrenia
    • Kirov G, Gumus D, Chen W, Norton N, Georgieva L, et al. (2008) Comparative genome hybridization suggests a role for NRXN1 and APBA2 in schizophrenia. Hum Mol Genet 17: 458-465.
    • (2008) Hum Mol Genet , vol.17 , pp. 458-465
    • Kirov, G.1    Gumus, D.2    Chen, W.3    Norton, N.4    Georgieva, L.5
  • 49
    • 51649107017 scopus 로고    scopus 로고
    • Rare chromosomal deletions and duplications increase risk of schizophrenia
    • The International Schizophrenia Consortium
    • The International Schizophrenia Consortium (2008) Rare chromosomal deletions and duplications increase risk of schizophrenia. Nature 455: 237-241.
    • (2008) Nature , vol.455 , pp. 237-241
  • 50
    • 42349088634 scopus 로고    scopus 로고
    • Rare structural variants disrupt multiple genes in neurodevelopmental pathways in schizophrenia
    • Walsh T, McClean JM, McCarthy SE, Addington AM, Pierce SB, et al. (2008) Rare structural variants disrupt multiple genes in neurodevelopmental pathways in schizophrenia. Science 320: 539-543.
    • (2008) Science , vol.320 , pp. 539-543
    • Walsh, T.1    McClean, J.M.2    McCarthy, S.E.3    Addington, A.M.4    Pierce, S.B.5
  • 51
    • 46249093584 scopus 로고    scopus 로고
    • Strong association of de novo copy number mutations with sporadic schizophrenia
    • Xu B, Roos JL, Levy S, van Rensburg EJ, Gogos JA, et al. (2008) Strong association of de novo copy number mutations with sporadic schizophrenia. Nat Genet 40: 880-885.
    • (2008) Nat Genet , vol.40 , pp. 880-885
    • Xu, B.1    Roos, J.L.2    Levy, S.3    van Rensburg, E.J.4    Gogos, J.A.5
  • 52
    • 33645418499 scopus 로고    scopus 로고
    • High mutation rates have driven extensive structural polymorphism among human Y chromosomes
    • Repping S, van Daalen SKM, Brown LG, Korver CM, Lange J, et al. (2006) High mutation rates have driven extensive structural polymorphism among human Y chromosomes. Nat Genet 38: 463-467.
    • (2006) Nat Genet , vol.38 , pp. 463-467
    • Repping, S.1    van Daalen, S.K.M.2    Brown, L.G.3    Korver, C.M.4    Lange, J.5
  • 54
    • 33846271432 scopus 로고    scopus 로고
    • Persistence problem in schizophrenia and mitochondrial DNA
    • Doi N, Hoshi Y (2007) Persistence problem in schizophrenia and mitochondrial DNA. Am J Med Genet Part B 144: 1-5.
    • (2007) Am J Med Genet , vol.144 , Issue.PART B , pp. 1-5
    • Doi, N.1    Hoshi, Y.2
  • 55
    • 34047244895 scopus 로고    scopus 로고
    • A resistance gene in disguise for schizophrenia?
    • Doi N, Itokawa M, Hoshi Y, Arai M, Furukawa A, et al. (2007) A resistance gene in disguise for schizophrenia? Am J Med Genet Part B 144: 165-173.
    • (2007) Am J Med Genet , vol.144 , Issue.PART B , pp. 165-173
    • Doi, N.1    Itokawa, M.2    Hoshi, Y.3    Arai, M.4    Furukawa, A.5
  • 56
    • 0242667149 scopus 로고    scopus 로고
    • A mitochondrial DNA sequence variant associated with schizophrenia and oxidative stress
    • Marchbanks RM, Ryan M, Day IN, Owen M, McGuffin P, et al. (2003) A mitochondrial DNA sequence variant associated with schizophrenia and oxidative stress. Schizophr Res 65: 33-38.
    • (2003) Schizophr Res , vol.65 , pp. 33-38
    • Marchbanks, R.M.1    Ryan, M.2    Day, I.N.3    Owen, M.4    McGuffin, P.5
  • 57
    • 14644414173 scopus 로고    scopus 로고
    • Mitochondrial DNA 3243A>G mutation and increased expression of LARS2 gene in the brains of patients with bipolar disorder and schizophrenia
    • Munakata K, Iwamoto K, Bundo M, Kato T (2005) Mitochondrial DNA 3243A>G mutation and increased expression of LARS2 gene in the brains of patients with bipolar disorder and schizophrenia. Biol Psychiatry 57: 525-532.
    • (2005) Biol Psychiatry , vol.57 , pp. 525-532
    • Munakata, K.1    Iwamoto, K.2    Bundo, M.3    Kato, T.4
  • 58
    • 33646075145 scopus 로고    scopus 로고
    • New variants in the mitochondrial genomes of schizophrenic patients
    • Martorell L, Segués T, Folch G, Valero J, Joven J, et al. (2006) New variants in the mitochondrial genomes of schizophrenic patients. Eur J Hum Genet 14: 520-528.
    • (2006) Eur J Hum Genet , vol.14 , pp. 520-528
    • Martorell, L.1    Segués, T.2    Folch, G.3    Valero, J.4    Joven, J.5
  • 60
    • 0033828761 scopus 로고    scopus 로고
    • Estimate of the mutation rate per nucleotide in humans
    • Nachman MW, Crowell SL (2000) Estimate of the mutation rate per nucleotide in humans. Genetics 156: 297-304.
    • (2000) Genetics , vol.156 , pp. 297-304
    • Nachman, M.W.1    Crowell, S.L.2
  • 63
    • 10744220971 scopus 로고    scopus 로고
    • Paternal and maternal age as risk factors for psychosis: Findings from Denmark, Sweden and Australia
    • El-Saadi O, Pedersen CB, McNeil TF, Saha S, Welham J, et al. (2004) Paternal and maternal age as risk factors for psychosis: findings from Denmark, Sweden and Australia. Schizophr Res 67: 227-236.
    • (2004) Schizophr Res , vol.67 , pp. 227-236
    • El-Saadi, O.1    Pedersen, C.B.2    McNeil, T.F.3    Saha, S.4    Welham, J.5
  • 66
    • 8544276579 scopus 로고    scopus 로고
    • Sipos A, Rasmussen F, Harrison G, Tynelius P, Lewis G, et al. (2004) Paternal age and schizophrenia; a population based cohort study. BMJ;doi:10.1136/bmj.38243.672396.55 (published 22 October 2004).
    • Sipos A, Rasmussen F, Harrison G, Tynelius P, Lewis G, et al. (2004) Paternal age and schizophrenia; a population based cohort study. BMJ;doi:10.1136/bmj.38243.672396.55 (published 22 October 2004).
  • 67
    • 0035024283 scopus 로고    scopus 로고
    • Comparison of statistical power between 2×2 allele frequency and allele positivity tables in case-control studies of complex disease genes
    • Ohashi J, Yamamoto S, Tsuchiya N, Hatta Y, Komata T, et al. (2001) Comparison of statistical power between 2×2 allele frequency and allele positivity tables in case-control studies of complex disease genes. Ann Hum Genet 65: 197-206.
    • (2001) Ann Hum Genet , vol.65 , pp. 197-206
    • Ohashi, J.1    Yamamoto, S.2    Tsuchiya, N.3    Hatta, Y.4    Komata, T.5
  • 68
    • 0036630062 scopus 로고    scopus 로고
    • the expected power of genome-wide linkage disequilibrium testing using single nucleotide polymorphism markers for detecting a low-frequency disease variant
    • Ohashi J, Tokunaga K (2002) the expected power of genome-wide linkage disequilibrium testing using single nucleotide polymorphism markers for detecting a low-frequency disease variant. Ann Hum Genet 66: 297-306.
    • (2002) Ann Hum Genet , vol.66 , pp. 297-306
    • Ohashi, J.1    Tokunaga, K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.