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Volumn 6, Issue 1, 2010, Pages 65-74

Racial Differences in Heart Failure Therapeutics

Author keywords

African Americans; Heart failure; Isosorbide dinitrate and hydralazine; Nitric oxide; Pharmacogenomics; Race; Renin angiotensin aldosterone system

Indexed keywords

ALDOSTERONE ANTAGONIST; ALDOSTERONE SYNTHASE; ALPHA ADRENERGIC RECEPTOR; ANGIOTENSIN RECEPTOR ANTAGONIST; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BISOPROLOL; BUCINDOLOL; CANDESARTAN; CARVEDILOL; DIGOXIN; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; ENALAPRIL; ENDOTHELIAL NITRIC OXIDE SYNTHASE; G PROTEIN COUPLED RECEPTOR KINASE 5; GUANINE NUCLEOTIDE BINDING PROTEIN BETA SUBUNIT; HYDRALAZINE PLUS ISOSORBIDE DINITRATE; METOPROLOL; NEUROHORMONE; NITRIC OXIDE; SPIRONOLACTONE; VASODILATOR AGENT;

EID: 70450185104     PISSN: 15517136     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.hfc.2009.08.006     Document Type: Review
Times cited : (12)

References (62)
  • 2
    • 0033602058 scopus 로고    scopus 로고
    • Racial differences in the outcome of left ventricular dysfunction
    • Dries D.L., Exner D.V., Gersh B.J., et al. Racial differences in the outcome of left ventricular dysfunction. N Engl J Med 340 (1999) 609-616
    • (1999) N Engl J Med , vol.340 , pp. 609-616
    • Dries, D.L.1    Exner, D.V.2    Gersh, B.J.3
  • 3
    • 0035799777 scopus 로고    scopus 로고
    • Lesser response to angiotensin-converting-enzyme inhibitor therapy in black as compared with white patients with left ventricular dysfunction
    • Exner D.V., Dries D.L., Domanski M.J., et al. Lesser response to angiotensin-converting-enzyme inhibitor therapy in black as compared with white patients with left ventricular dysfunction. N Engl J Med 344 (2001) 1351-1357
    • (2001) N Engl J Med , vol.344 , pp. 1351-1357
    • Exner, D.V.1    Dries, D.L.2    Domanski, M.J.3
  • 4
    • 19644400578 scopus 로고    scopus 로고
    • Combination of isosorbide dinitrate and hydralazine in blacks with heart failure
    • Taylor A.L., Ziesche S., Yancy C., et al. Combination of isosorbide dinitrate and hydralazine in blacks with heart failure. N Engl J Med 351 (2004) 2049-2057
    • (2004) N Engl J Med , vol.351 , pp. 2049-2057
    • Taylor, A.L.1    Ziesche, S.2    Yancy, C.3
  • 5
    • 45149113054 scopus 로고    scopus 로고
    • Characteristics and outcomes in African American patients with decompensated heart failure
    • Kamath S.A., Drazner M.H., Wynne J., et al. Characteristics and outcomes in African American patients with decompensated heart failure. Arch Intern Med 168 (2008) 1152-1158
    • (2008) Arch Intern Med , vol.168 , pp. 1152-1158
    • Kamath, S.A.1    Drazner, M.H.2    Wynne, J.3
  • 6
    • 43049098571 scopus 로고    scopus 로고
    • Quality of care of and outcomes for African Americans hospitalized with heart failure
    • Yancy C.W., Abraham W.T., Albert N.M., et al. Quality of care of and outcomes for African Americans hospitalized with heart failure. J Am Coll Cardiol 51 (2008) 1675-1684
    • (2008) J Am Coll Cardiol , vol.51 , pp. 1675-1684
    • Yancy, C.W.1    Abraham, W.T.2    Albert, N.M.3
  • 7
    • 62749131642 scopus 로고    scopus 로고
    • Racial differences in incident heart failure among young adults
    • Bibbins-Domingo K., Pletcher M.J., Lin F., et al. Racial differences in incident heart failure among young adults. N Engl J Med 360 (2009) 1179-1180
    • (2009) N Engl J Med , vol.360 , pp. 1179-1180
    • Bibbins-Domingo, K.1    Pletcher, M.J.2    Lin, F.3
  • 8
    • 0025913812 scopus 로고
    • Effect of enalapril on survival in patients with reduced left ventricular ejection fraction and congestive heart failure. The SOLVD investigators
    • Effect of enalapril on survival in patients with reduced left ventricular ejection fraction and congestive heart failure. The SOLVD investigators. N Engl J Med 325 (1991) 293-302
    • (1991) N Engl J Med , vol.325 , pp. 293-302
  • 9
    • 0026785561 scopus 로고
    • Effect of enalapril on mortality and the development of heart failure in asymptomatic patients with reduced left ventricular ejection fractions. The SOLVD investigators
    • [Erratum, N Engl J Med 1992;327:1768]
    • Effect of enalapril on mortality and the development of heart failure in asymptomatic patients with reduced left ventricular ejection fractions. The SOLVD investigators. N Engl J Med 327 (1992) 685-691 [Erratum, N Engl J Med 1992;327:1768]
    • (1992) N Engl J Med , vol.327 , pp. 685-691
  • 10
    • 0022623381 scopus 로고
    • Effect of vasodilator therapy on mortality in chronic congestive heart failure: results of a Veterans Administration Cooperative Study (V-HeFT)
    • Cohn J.N., Archibald D.G., Ziesche S., et al. Effect of vasodilator therapy on mortality in chronic congestive heart failure: results of a Veterans Administration Cooperative Study (V-HeFT). N Engl J Med 314 (1986) 1547-1552
    • (1986) N Engl J Med , vol.314 , pp. 1547-1552
    • Cohn, J.N.1    Archibald, D.G.2    Ziesche, S.3
  • 11
    • 0025770138 scopus 로고
    • A comparison of enalapril with hydralazine-isosorbide dinitrate in the treatment of chronic congestive heart failure
    • Cohn J.N., Johnson G., Ziesche S., et al. A comparison of enalapril with hydralazine-isosorbide dinitrate in the treatment of chronic congestive heart failure. N Engl J Med 325 (1991) 303-310
    • (1991) N Engl J Med , vol.325 , pp. 303-310
    • Cohn, J.N.1    Johnson, G.2    Ziesche, S.3
  • 12
    • 0032836517 scopus 로고    scopus 로고
    • Racial differences in response to therapy for heart failure: analysis of the Vasodilator-Heart Failure trials. Vasodilator-Heart Failure Trial Study Group
    • Carson P., Ziesche S., Johnson G., et al. Racial differences in response to therapy for heart failure: analysis of the Vasodilator-Heart Failure trials. Vasodilator-Heart Failure Trial Study Group. J Card Fail 5 (1999) 178-187
    • (1999) J Card Fail , vol.5 , pp. 178-187
    • Carson, P.1    Ziesche, S.2    Johnson, G.3
  • 13
    • 0030722171 scopus 로고    scopus 로고
    • Vasodilation in black Americans: attenuated nitric oxide-mediated responses
    • Stein C.M., Lang C.C., Nelson R., et al. Vasodilation in black Americans: attenuated nitric oxide-mediated responses. Clin Pharmacol Ther 62 (1997) 436-443
    • (1997) Clin Pharmacol Ther , vol.62 , pp. 436-443
    • Stein, C.M.1    Lang, C.C.2    Nelson, R.3
  • 14
    • 0031838355 scopus 로고    scopus 로고
    • Racial differences in nitric oxide-mediated vasodilator response to mental stress in the forearm circulation
    • Cardillo C., Kilcoyne C.M., Cannon III R.O., et al. Racial differences in nitric oxide-mediated vasodilator response to mental stress in the forearm circulation. Hypertension 31 (1998) 1235-1239
    • (1998) Hypertension , vol.31 , pp. 1235-1239
    • Cardillo, C.1    Kilcoyne, C.M.2    Cannon III, R.O.3
  • 15
    • 0036327572 scopus 로고    scopus 로고
    • Effects of black race on forearm resistance vessel function
    • Kahn D.F., Duffy S.J., Tomasian D., et al. Effects of black race on forearm resistance vessel function. Hypertension 40 (2002) 195-201
    • (2002) Hypertension , vol.40 , pp. 195-201
    • Kahn, D.F.1    Duffy, S.J.2    Tomasian, D.3
  • 16
    • 2142744871 scopus 로고    scopus 로고
    • The African-American Heart Failure Trial (A-HeFT): rationale and methodology
    • Taylor A.L. The African-American Heart Failure Trial (A-HeFT): rationale and methodology. J Card Fail 9 Suppl (2003) S216-S219
    • (2003) J Card Fail , vol.9 , Issue.SUPPL
    • Taylor, A.L.1
  • 17
    • 0035978801 scopus 로고    scopus 로고
    • A trial of the beta-blocker bucindolol in patients with advanced chronic heart failure
    • The Beta-Blocker Evaluation of Survival Trial Investigators. A trial of the beta-blocker bucindolol in patients with advanced chronic heart failure. N Engl J Med 344 (2001) 1659-1667
    • (2001) N Engl J Med , vol.344 , pp. 1659-1667
    • The Beta-Blocker Evaluation of Survival Trial Investigators1
  • 18
    • 0033549290 scopus 로고    scopus 로고
    • Effect of metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL Randomised Intervention Trial in Congestive Heart Failure (MERIT-HF)
    • Effect of metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL Randomised Intervention Trial in Congestive Heart Failure (MERIT-HF). Lancet 353 (1999) 2001-2007
    • (1999) Lancet , vol.353 , pp. 2001-2007
  • 19
    • 0035978763 scopus 로고    scopus 로고
    • Effect of carvedilol on survival in severe chronic heart disease
    • Packer M., Coats A.J.S., Fowler M.B., et al. Effect of carvedilol on survival in severe chronic heart disease. N Engl J Med 344 (2001) 1651-1658
    • (2001) N Engl J Med , vol.344 , pp. 1651-1658
    • Packer, M.1    Coats, A.J.S.2    Fowler, M.B.3
  • 20
    • 0033514046 scopus 로고    scopus 로고
    • The cardiac insufficiency bisoprolol study II (CIBIS-II): a randomized trial
    • CIBIS-II Investigators and Committees. The cardiac insufficiency bisoprolol study II (CIBIS-II): a randomized trial. Lancet 353 (1999) 9-13
    • (1999) Lancet , vol.353 , pp. 9-13
    • CIBIS-II Investigators and Committees1
  • 21
    • 0003305802 scopus 로고    scopus 로고
    • Effect of beta-blockade on mortality in African-Americans: the Beta-blocker Evaluation of Survival Trial
    • II
    • Eichhorn E.J., Domanski M.J., Adams K., et al. Effect of beta-blockade on mortality in African-Americans: the Beta-blocker Evaluation of Survival Trial. Circulation 102 Suppl II (2000) 778 II
    • (2000) Circulation , vol.102 , Issue.SUPPL. II , pp. 778
    • Eichhorn, E.J.1    Domanski, M.J.2    Adams, K.3
  • 22
    • 0242545913 scopus 로고    scopus 로고
    • Hemodynamic, myocardial functional and neurohormonal responses to beta-blockade in black vs non-black patients in BEST
    • II
    • Eichhorn E.J., Domanski M.J., Adams K., et al. Hemodynamic, myocardial functional and neurohormonal responses to beta-blockade in black vs non-black patients in BEST. Circulation 102 Suppl II (2000) 778 II
    • (2000) Circulation , vol.102 , Issue.SUPPL. II , pp. 778
    • Eichhorn, E.J.1    Domanski, M.J.2    Adams, K.3
  • 23
    • 0037150153 scopus 로고    scopus 로고
    • Bucindolol displays intrinsic sympathomimetic activity in human myocardium
    • Andreka P., Aiyar N., Olson L.C., et al. Bucindolol displays intrinsic sympathomimetic activity in human myocardium. Circulation 105 (2002) 2429-2434
    • (2002) Circulation , vol.105 , pp. 2429-2434
    • Andreka, P.1    Aiyar, N.2    Olson, L.C.3
  • 24
    • 0012867263 scopus 로고    scopus 로고
    • Effect of carvedilol in black patients with severe chronic heart failure: results of the COPERNICUS study
    • II-754
    • Carson P., Fowler M.B., Mohacsi P., et al. Effect of carvedilol in black patients with severe chronic heart failure: results of the COPERNICUS study. Circulation 104 Suppl II (2001) II-754
    • (2001) Circulation , vol.104 , Issue.SUPPL. II
    • Carson, P.1    Fowler, M.B.2    Mohacsi, P.3
  • 25
    • 0035799754 scopus 로고    scopus 로고
    • Race and the response to adrenergic blockade with carvedilol in patients with chronic heart failure
    • Yancy C.W., Fowler M.B., Colucci W.S., et al. Race and the response to adrenergic blockade with carvedilol in patients with chronic heart failure. N Engl J Med 344 (2001) 1358-1365
    • (2001) N Engl J Med , vol.344 , pp. 1358-1365
    • Yancy, C.W.1    Fowler, M.B.2    Colucci, W.S.3
  • 26
    • 0042063780 scopus 로고    scopus 로고
    • Metoprolol CR/XL in black patients with heart failure (from the Metoprolol CR/XL Randomized Intervention Trial in Chronic Heart Failure)
    • Goldstein S., Deedwania P., Gottlieb S., et al. Metoprolol CR/XL in black patients with heart failure (from the Metoprolol CR/XL Randomized Intervention Trial in Chronic Heart Failure). Am J Cardiol 92 (2003) 478-480
    • (2003) Am J Cardiol , vol.92 , pp. 478-480
    • Goldstein, S.1    Deedwania, P.2    Gottlieb, S.3
  • 27
    • 0038408846 scopus 로고    scopus 로고
    • Efficacy of angiotensin-converting enzyme inhibitors and beta-blockers in the management of left ventricular systolic dysfunction according to race, gender, and diabetic status. A meta-analysis of major clinical trials
    • Shekelle P.G., Rich M.W., Morton S.C., et al. Efficacy of angiotensin-converting enzyme inhibitors and beta-blockers in the management of left ventricular systolic dysfunction according to race, gender, and diabetic status. A meta-analysis of major clinical trials. J Am Coll Cardiol 41 (2003) 1529-1538
    • (2003) J Am Coll Cardiol , vol.41 , pp. 1529-1538
    • Shekelle, P.G.1    Rich, M.W.2    Morton, S.C.3
  • 28
    • 0033517302 scopus 로고    scopus 로고
    • The effect of spironolactone on morbidity and mortality in patients with severe heart failure
    • Pitt B., Zannad F., Remme W.J., et al. The effect of spironolactone on morbidity and mortality in patients with severe heart failure. N Engl J Med 341 (1999) 709-717
    • (1999) N Engl J Med , vol.341 , pp. 709-717
    • Pitt, B.1    Zannad, F.2    Remme, W.J.3
  • 29
    • 0037417252 scopus 로고    scopus 로고
    • Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction
    • Pitt B., Remme W., Zannad F., et al. Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction. N Engl J Med 348 (2003) 1309-1321
    • (2003) N Engl J Med , vol.348 , pp. 1309-1321
    • Pitt, B.1    Remme, W.2    Zannad, F.3
  • 30
    • 0042410539 scopus 로고    scopus 로고
    • Effects of candesartan on mortality and morbidity in patients with chronic heart failure: the CHARM-Overall programme
    • Pfeffer M.A., Swedberg K., Granger G.B., et al. Effects of candesartan on mortality and morbidity in patients with chronic heart failure: the CHARM-Overall programme. Lancet 362 (2003) 759-766
    • (2003) Lancet , vol.362 , pp. 759-766
    • Pfeffer, M.A.1    Swedberg, K.2    Granger, G.B.3
  • 31
    • 0035818884 scopus 로고    scopus 로고
    • A randomized trial of the angiotensin-receptor blocker valsartan in chronic heart failure
    • Cohn J.N., and Tognoni G. A randomized trial of the angiotensin-receptor blocker valsartan in chronic heart failure. N Engl J Med 345 (2001) 1667-1675
    • (2001) N Engl J Med , vol.345 , pp. 1667-1675
    • Cohn, J.N.1    Tognoni, G.2
  • 32
    • 2042437650 scopus 로고    scopus 로고
    • Initial sequencing and analysis of the human genome
    • International Human Genome Sequencing Consortium. Initial sequencing and analysis of the human genome. Nature 409 (2001) 860-921
    • (2001) Nature , vol.409 , pp. 860-921
    • International Human Genome Sequencing Consortium1
  • 34
    • 0035895505 scopus 로고    scopus 로고
    • The sequence of the human genome
    • [Erratum, Science 2001;292: p. 1838]
    • Venter J.C., Adams M.D., Myers E.W., et al. The sequence of the human genome. Science 291 (2001) 1304-1351 [Erratum, Science 2001;292: p. 1838]
    • (2001) Science , vol.291 , pp. 1304-1351
    • Venter, J.C.1    Adams, M.D.2    Myers, E.W.3
  • 35
    • 7244245762 scopus 로고    scopus 로고
    • Finishing the euchromatic sequence of the human genome
    • International Human Genome Sequencing Consortium. Finishing the euchromatic sequence of the human genome. Nature 431 (2004) 931-945
    • (2004) Nature , vol.431 , pp. 931-945
    • International Human Genome Sequencing Consortium1
  • 36
    • 0025165779 scopus 로고
    • An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels
    • Rigat B., Hubert C., Alhenc-Gelas F., et al. An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels. J Clin Invest 86 (1990) 1343-1346
    • (1990) J Clin Invest , vol.86 , pp. 1343-1346
    • Rigat, B.1    Hubert, C.2    Alhenc-Gelas, F.3
  • 37
    • 0026651907 scopus 로고
    • Evidence from combined segregation and linkage analysis that a variant of the angiotensin I-converting enzyme (ACE) gene controls plasma ACE levels
    • Tiret L., Rigat B., Visvikis S., et al. Evidence from combined segregation and linkage analysis that a variant of the angiotensin I-converting enzyme (ACE) gene controls plasma ACE levels. Am J Hum Genet 51 (1992) 197-205
    • (1992) Am J Hum Genet , vol.51 , pp. 197-205
    • Tiret, L.1    Rigat, B.2    Visvikis, S.3
  • 38
    • 0033498922 scopus 로고    scopus 로고
    • Angiotensin I to angiotensin II conversion in the human forearm and leg. Effect of the angiotensin converting enzyme gene insertion/deletion polymorphism
    • Danser A.H., Deinum J., Osterop A.P., et al. Angiotensin I to angiotensin II conversion in the human forearm and leg. Effect of the angiotensin converting enzyme gene insertion/deletion polymorphism. J Hypertens 17 (1999) 1867-1872
    • (1999) J Hypertens , vol.17 , pp. 1867-1872
    • Danser, A.H.1    Deinum, J.2    Osterop, A.P.3
  • 39
    • 0030198578 scopus 로고    scopus 로고
    • The DD genotype of the angiotensin-converting enzyme gene is associated with increased mortality in idiopathic heart failure
    • Andersson B., and Sylven C. The DD genotype of the angiotensin-converting enzyme gene is associated with increased mortality in idiopathic heart failure. J Am Coll Cardiol 28 (1996) 162-167
    • (1996) J Am Coll Cardiol , vol.28 , pp. 162-167
    • Andersson, B.1    Sylven, C.2
  • 40
    • 0035369667 scopus 로고    scopus 로고
    • Failure of aldosterone suppression despite angiotensin-converting enzyme (ACE) inhibitor administration in chronic heart failure is associated with ACE DD genotype
    • Cicoira M., Zanolla L., Rossi A., et al. Failure of aldosterone suppression despite angiotensin-converting enzyme (ACE) inhibitor administration in chronic heart failure is associated with ACE DD genotype. J Am Coll Cardiol 37 (2001) 1808-1821
    • (2001) J Am Coll Cardiol , vol.37 , pp. 1808-1821
    • Cicoira, M.1    Zanolla, L.2    Rossi, A.3
  • 41
    • 0035957262 scopus 로고    scopus 로고
    • Pharmacogenetic interactions between beta-blocker therapy and the angiotensin-converting enzyme deletion polymorphism in patients with congestive heart failure
    • McNamara D.M., Holubkov R., Janosko K., et al. Pharmacogenetic interactions between beta-blocker therapy and the angiotensin-converting enzyme deletion polymorphism in patients with congestive heart failure. Circulation 103 (2001) 1644-1648
    • (2001) Circulation , vol.103 , pp. 1644-1648
    • McNamara, D.M.1    Holubkov, R.2    Janosko, K.3
  • 42
    • 8144221236 scopus 로고    scopus 로고
    • Pharmacogenetic interactions between angiotensin-converting enzyme inhibitor therapy and the angiotensin-converting enzyme deletion polymorphism in patients with congestive heart failure
    • McNamara D.M., Holubkov R., Postava L., et al. Pharmacogenetic interactions between angiotensin-converting enzyme inhibitor therapy and the angiotensin-converting enzyme deletion polymorphism in patients with congestive heart failure. J Am Coll Cardiol 44 (2004) 2019-2026
    • (2004) J Am Coll Cardiol , vol.44 , pp. 2019-2026
    • McNamara, D.M.1    Holubkov, R.2    Postava, L.3
  • 43
    • 16644388739 scopus 로고    scopus 로고
    • Impact of angiotensin-converting enzyme gene polymorphism on neurohormonal responses to high- versus low-dose enalapril in advanced heart failure
    • Tang W.H.W., Vagelos R.H., Yee Y.G., et al. Impact of angiotensin-converting enzyme gene polymorphism on neurohormonal responses to high- versus low-dose enalapril in advanced heart failure. Am Heart J 148 (2004) 889-894
    • (2004) Am Heart J , vol.148 , pp. 889-894
    • Tang, W.H.W.1    Vagelos, R.H.2    Yee, Y.G.3
  • 44
    • 0033584561 scopus 로고    scopus 로고
    • Racial differences in the frequencies of cardiac beta1-adrenergic receptor polymorphisms: analysis of c145A>G and c1165G>C
    • Moore J.D., Mason D.A., Green S.A., et al. Racial differences in the frequencies of cardiac beta1-adrenergic receptor polymorphisms: analysis of c145A>G and c1165G>C. Hum Mutat 14 (1999) 271
    • (1999) Hum Mutat , vol.14 , pp. 271
    • Moore, J.D.1    Mason, D.A.2    Green, S.A.3
  • 45
    • 0034744634 scopus 로고    scopus 로고
    • Arg389Gly beta1-adrenoceptor polymorphism varies in frequency among different ethnic groups but does not alter response in vivo
    • Xie H.G., Dishy V., Sofowora G., et al. Arg389Gly beta1-adrenoceptor polymorphism varies in frequency among different ethnic groups but does not alter response in vivo. Pharmacogenetics 11 (2001) 191-197
    • (2001) Pharmacogenetics , vol.11 , pp. 191-197
    • Xie, H.G.1    Dishy, V.2    Sofowora, G.3
  • 46
    • 33746603033 scopus 로고    scopus 로고
    • A polymorphism within a conserved beta1-adrenergic receptor motif alters cardiac function and beta-blocker response in human heart failure
    • Liggett S.B., Mialet-Perez J., Thaneemit-Chen S., et al. A polymorphism within a conserved beta1-adrenergic receptor motif alters cardiac function and beta-blocker response in human heart failure. Proc Natl Acad Sci U S A 103 (2006) 11288-11293
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 11288-11293
    • Liggett, S.B.1    Mialet-Perez, J.2    Thaneemit-Chen, S.3
  • 47
    • 0041466430 scopus 로고    scopus 로고
    • An evaluation of the beta-1 adrenergic receptor Arg389Gly polymorphism in individuals with heart failure: a MERIT-HF sub-study
    • White H.L., de Boer R.A., Maqbool A., et al. An evaluation of the beta-1 adrenergic receptor Arg389Gly polymorphism in individuals with heart failure: a MERIT-HF sub-study. Eur J Heart Fail 5 (2003) 463-468
    • (2003) Eur J Heart Fail , vol.5 , pp. 463-468
    • White, H.L.1    de Boer, R.A.2    Maqbool, A.3
  • 48
    • 43249124512 scopus 로고    scopus 로고
    • A GRK5 polymorphism that inhibits beta-adrenergic receptor signaling is protective in heart failure
    • Liggett S.B., Cresci S., Kelly R.J., et al. A GRK5 polymorphism that inhibits beta-adrenergic receptor signaling is protective in heart failure. Nat Med 14 (2008) 510-517
    • (2008) Nat Med , vol.14 , pp. 510-517
    • Liggett, S.B.1    Cresci, S.2    Kelly, R.J.3
  • 49
    • 33748428075 scopus 로고    scopus 로고
    • Aldosterone synthase promoter polymorphism predicts outcome in African Americans with heart failure. Results from the A-HeFT trial
    • McNamara D.M., Tam S.W., Sabolinski M.L., et al. Aldosterone synthase promoter polymorphism predicts outcome in African Americans with heart failure. Results from the A-HeFT trial. J Am Coll Cardiol 48 (2006) 1277-1282
    • (2006) J Am Coll Cardiol , vol.48 , pp. 1277-1282
    • McNamara, D.M.1    Tam, S.W.2    Sabolinski, M.L.3
  • 50
    • 62649122885 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase (NOS3) polymorphisms in African Americans with heart failure: results from the A-HeFT trial
    • McNamara D.M., Tam S.W., Sabolinski M.L., et al. Endothelial nitric oxide synthase (NOS3) polymorphisms in African Americans with heart failure: results from the A-HeFT trial. J Card Fail 15 (2009) 191-198
    • (2009) J Card Fail , vol.15 , pp. 191-198
    • McNamara, D.M.1    Tam, S.W.2    Sabolinski, M.L.3
  • 51
    • 0029020640 scopus 로고
    • Haplotype analysis of CYP11B2
    • White P.C., and Slutsker L. Haplotype analysis of CYP11B2. Endocr Res 21 (1995) 437-442
    • (1995) Endocr Res , vol.21 , pp. 437-442
    • White, P.C.1    Slutsker, L.2
  • 52
    • 0031846630 scopus 로고    scopus 로고
    • Structural analysis and evaluation of the aldosterone synthase gene in hypertension
    • Brand E., Chatelain N., Mulatero P., et al. Structural analysis and evaluation of the aldosterone synthase gene in hypertension. Hypertension 32 (1998) 198-204
    • (1998) Hypertension , vol.32 , pp. 198-204
    • Brand, E.1    Chatelain, N.2    Mulatero, P.3
  • 53
    • 0033621809 scopus 로고    scopus 로고
    • Lys173Arg and - 344T/C variants of CYP11B2 in Japanese patients with low-renin hypertension
    • Komiya I., Yamada T., Takara M., et al. Lys173Arg and - 344T/C variants of CYP11B2 in Japanese patients with low-renin hypertension. Hypertension 35 (2000) 699-703
    • (2000) Hypertension , vol.35 , pp. 699-703
    • Komiya, I.1    Yamada, T.2    Takara, M.3
  • 54
    • 31944444788 scopus 로고    scopus 로고
    • Low-renin hypertension with relative aldosterone excess is associated with impaired NO-mediated vasodilation
    • Duffy S.J., Biegelsen E.S., Eberhardt R.T., et al. Low-renin hypertension with relative aldosterone excess is associated with impaired NO-mediated vasodilation. Hypertension 46 (2005) 707-713
    • (2005) Hypertension , vol.46 , pp. 707-713
    • Duffy, S.J.1    Biegelsen, E.S.2    Eberhardt, R.T.3
  • 55
    • 0031713784 scopus 로고    scopus 로고
    • Association between a polymorphism in the G protein β3 subunit gene and lower renin and elevated diastolic blood pressure levels
    • Schunkert H., Hense H.W., Döring A., et al. Association between a polymorphism in the G protein β3 subunit gene and lower renin and elevated diastolic blood pressure levels. Hypertension 32 (1998) 510-513
    • (1998) Hypertension , vol.32 , pp. 510-513
    • Schunkert, H.1    Hense, H.W.2    Döring, A.3
  • 56
    • 70450171079 scopus 로고    scopus 로고
    • G protein beta 3 subunit (GNB3) genotype predicts enhanced benefit of fixed-dose isosorbide dinitrate and hydralazine-results of the A-HeFT trial
    • II
    • G protein beta 3 subunit (GNB3) genotype predicts enhanced benefit of fixed-dose isosorbide dinitrate and hydralazine-results of the A-HeFT trial. Circulation 114 Suppl 18 (2006) 442 II
    • (2006) Circulation , vol.114 , Issue.SUPPL. 18 , pp. 442
  • 57
    • 0033405439 scopus 로고    scopus 로고
    • Association between the C285T polymorphism of the G protein β3-subunit gene and hypertension in blacks
    • Dong Y., Zhu H., Sagnella G.A., et al. Association between the C285T polymorphism of the G protein β3-subunit gene and hypertension in blacks. Hypertension 34 (1999) 1193-1196
    • (1999) Hypertension , vol.34 , pp. 1193-1196
    • Dong, Y.1    Zhu, H.2    Sagnella, G.A.3
  • 58
    • 17344366286 scopus 로고    scopus 로고
    • Association of a human G-protein β3 subunit variant with hypertension
    • Siffert W., Rosskopf D., Siffert G., et al. Association of a human G-protein β3 subunit variant with hypertension. Nat Genet 18 (1998) 45-48
    • (1998) Nat Genet , vol.18 , pp. 45-48
    • Siffert, W.1    Rosskopf, D.2    Siffert, G.3
  • 59
    • 0032588245 scopus 로고    scopus 로고
    • G-protein β3 subunit C825T variant and ambulatory blood pressure in essential hypertension
    • Beige J., Hohenbleicher H., Distler A., et al. G-protein β3 subunit C825T variant and ambulatory blood pressure in essential hypertension. Hypertension 33 (1999) 1049-1051
    • (1999) Hypertension , vol.33 , pp. 1049-1051
    • Beige, J.1    Hohenbleicher, H.2    Distler, A.3
  • 60
    • 0032217177 scopus 로고    scopus 로고
    • G-protein β3 subunit gene (GNB3) variant in causation of essential hypertension
    • Benjafield A.V., Jeyasingam C.L., Nyholt D.R., et al. G-protein β3 subunit gene (GNB3) variant in causation of essential hypertension. Hypertension 32 (1998) 1094-1097
    • (1998) Hypertension , vol.32 , pp. 1094-1097
    • Benjafield, A.V.1    Jeyasingam, C.L.2    Nyholt, D.R.3
  • 61
    • 0035174449 scopus 로고    scopus 로고
    • Effects of ethnicity on the distribution of clinically relevant endothelial nitric oxide variants
    • Tanus-Santos J.E., Desai M., and Flockhart D.A. Effects of ethnicity on the distribution of clinically relevant endothelial nitric oxide variants. Pharmacogenetics 11 (2001) 719-725
    • (2001) Pharmacogenetics , vol.11 , pp. 719-725
    • Tanus-Santos, J.E.1    Desai, M.2    Flockhart, D.A.3
  • 62
    • 23444461576 scopus 로고    scopus 로고
    • Influence of the eNOS gene on development of blood pressure and left ventricular mss: longitudinal findings in multiethnic youth
    • Zhu H., Wang X., Dong Y., et al. Influence of the eNOS gene on development of blood pressure and left ventricular mss: longitudinal findings in multiethnic youth. Pharmacogenet Genomics 15 (2005) 669-675
    • (2005) Pharmacogenet Genomics , vol.15 , pp. 669-675
    • Zhu, H.1    Wang, X.2    Dong, Y.3


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