The soluble pattern recognition receptor pentraxin-3 in innate immunity, inflammation and fertility

Journal of Reproductive Immunology

Volumn 83, Issue 1-2, 2009, Pages 128-133

  Garlanda, Cecilia ^a   Maina, Virginia ^a   Cotena, Alessia ^a   Moalli, Federica ^a  

^a HUMANITAS CLINICAL AND RESEARCH CENTER   (Italy)

Author keywords

Fertility; Inflammation; Innate immunity; Pentraxin

Indexed keywords

CYTOKINE; PENTRAXIN 3;

AMINO TERMINAL SEQUENCE; ANGIOGENESIS; ANTIGEN ANTIBODY REACTION; ANTIGEN PRESENTING CELL; ARTICLE; BLASTOCYST; CELL PROLIFERATION; CELLULAR IMMUNITY; CLINICAL FEATURE; CYTOKINE PRODUCTION; DECIDUALIZATION; EXTRACELLULAR MATRIX; FEMALE FERTILITY; FEMALE INFERTILITY; GENE EXPRESSION; GENE MUTATION; GENE TARGETING; GENETIC CONSERVATION; HUMAN; HUMORAL IMMUNITY; IMMUNOMODULATION; IMMUNOSTIMULATION; INFLAMMATION; INNATE IMMUNITY; MOLECULAR EVOLUTION; NONHUMAN; OVULATION; PATHOPHYSIOLOGY; PHAGOCYTOSIS; PREECLAMPSIA; PREGNANCY DISORDER; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; SYNCYTIOTROPHOBLAST; TROPHOBLAST;

ANIMALS; C-REACTIVE PROTEIN; FEMALE; FERTILITY; HUMANS; IMMUNITY, INNATE; INFLAMMATION; NEOVASCULARIZATION, PHYSIOLOGIC; PREGNANCY; RECEPTORS, PATTERN RECOGNITION; SERUM AMYLOID P-COMPONENT;

EID: 70449729332     PISSN: 01650378     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jri.2009.05.006     Document Type: Article

References (39)

1. Assi F., Fruscio R., Bonardi C., Ghidini A., Allavena P., Mantovani A., and Locatelli A. Pentraxin 3 in plasma and vaginal fluid in women with preterm delivery. BJOG 114 (2007) 143-147
2. Bottazzi B., Vouret-Craviari V., Bastone A., De Gioia L., Matteucci C., Peri G., Spreafico F., Pausa M., D'Ettorre C., Gianazza E., Tagliabue A., Salmona M., Tedesco F., Introna M., and Mantovani A. Multimer formation and ligand recognition by the long pentraxin PTX3. Similarities and differences with the short pentraxins C-reactive protein and serum amyloid P component. J. Biol. Chem. 272 (1997) 32817-32823
3. Bottazzi B., Garlanda C., Salvatori G., Jeannin P., Manfredi A., and Mantovani A. Pentraxins as a key component of innate immunity. Curr. Opin. Immunol. 18 (2006) 10-15
4. Bozza S., Bistoni F., Gaziano R., Pitzurra L., Zelante T., Bonifazi P., Perruccio K., Bellocchio S., Neri M., Iorio A.M., Salvatori G., De Santis R., Calvitti M., Doni A., Garlanda C., Mantovani A., and Romani L. Pentraxin 3 protects from MCMV infection and reactivation through TLR sensing pathways leading to IRF3 activation. Blood 108 (2006) 3387-3396
5. Brinkmann V., Reichard U., Goosmann C., Fauler B., Uhlemann Y., Weiss D.S., Weinrauch Y., and Zychlinsky A. Neutrophil extracellular traps kill bacteria. Science 303 (2004) 1532-1535
6. Cetin I., Cozzi V., Pasqualini F., Nebuloni M., Garlanda C., Vago L., Pardi G., and Mantovani A. Elevated maternal levels of the long pentraxin 3 (PTX3) in preeclampsia and intrauterine growth restriction. Am. J. Obstet. Gynecol. 194 (2006) 1347-1353
7. Cotena A., Maina V., Sironi M., Bottazzi B., Jeannin P., Vecchi A., Corvaia N., Daha M.R., Mantovani A., and Garlanda C. Complement dependent amplification of the innate response to a cognate microbial ligand by the long pentraxin PTX3. J. Immunol. 179 (2007) 6311-6317
8. Deban L., Jarva H., Lehtinen M.J., Bottazzi B., Bastone A., Doni A., Jokiranta T.S., Mantovani A., and Meri S. Binding of the long pentraxin PTX3 to Factor H: interacting domains and function in the regulation of complement activation. J. Immunol. 181 (2008) 8433-8440
9. Doni A., Peri G., Chieppa M., Allavena P., Pasqualini F., Vago L., Romani L., Garlanda C., and Mantovani A. Production of the soluble pattern recognition receptor PTX3 by myeloid, but not plasmacytoid, dendritic cells. Eur. J. Immunol. 33 (2003) 2886-2893
10. Doni A., Michela M., Bottazzi B., Peri G., Valentino S., Polentarutti N., Garlanda C., and Mantovani A. Regulation of PTX3, a key component of humoral innate immunity in human dendritic cells: stimulation by IL-10 and inhibition by IFN-gamma. J. Leukoc. Biol. 79 (2006) 797-802
11. Doni A., Paffoni A., Nebuloni M., Ragni G., Pasqualini F., Valentino S., Bonetti S., Mantovani A., Somigliana E., and Garlanda C. The long pentraxin 3 is a soluble and cell-associated component of the human semen. Int. J. Androl. 32 3 (2009) 255-264
12. Doni A., Mantovani G., Porta C., Tuckermann J., Reichardt H.M., Kleiman A., Sironi M., Rubino L., Pasqualini F., Nebuloni M., Signorini S., Peri G., Sica A., Beck-Peccoz P., Bottazzi B., and Mantovani A. Cell-specific regulation of PTX3 by glucocorticoid hormones in hematopoietic and nonhematopoietic cells. J. Biol. Chem. 283 (2008) 29983-29992
13. Garlanda C., Hirsch E., Bozza S., Salustri A., De Acetis M., Nota R., Maccagno A., Riva F., Bottazzi B., Peri G., Doni A., Vago L., Botto M., De Santis R., Carminati P., Siracusa G., Altruda F., Vecchi A., Romani L., and Mantovani A. Non-redundant role of the long pentraxin PTX3 in anti-fungal innate immune response. Nature 420 (2002) 182-186
14. Garlanda C., Bottazzi B., Bastone A., and Mantovani A. Pentraxins at the crossroads between innate immunity, inflammation, matrix deposition, and female fertility. Annu. Rev. Immunol. 23 (2005) 337-366
15. Garlanda C., Maina V., Martinez de la Torre Y., Nebuloni M., and Locati M. Inflammatory reaction and implantation: the new entries PTX3 and D6. Placenta 29 Suppl. B (2008) 129-134
16. Girardi G., Bulla R., Salmon J.E., and Tedesco F. The complement system in the pathophysiology of pregnancy. Mol. Immunol. 43 (2006) 68-77
17. Hess A.P., Hamilton A.E., Talbi S., Dosiou C., Nyegaard M., Nayak N., Genbecev-Krtolica O., Mavrogianis P., Ferrer K., Kruessel J., Fazleabas A.T., Fisher S.J., and Giudice L.C. Decidual stromal cell response to paracrine signals from the trophoblast: amplification of immune and angiogenic modulators. Biol. Reprod. 76 (2007) 102-117
18. Inforzato A., Peri G., Doni A., Garlanda C., Mantovani A., Bastone A., Carpentieri A., Amoresano A., Pucci P., Roos A., Daha M.R., Vincenti S., Gallo G., Carminati P., De Santis R., and Salvatori G. Structure and function of the long pentraxin PTX3 glycosidic moiety: fine-tuning of the interaction with C1q and complement activation. Biochemistry 45 (2006) 11540-11551
19. Jaillon S., Peri G., Delneste Y., Fremaux I., Doni A., Moalli F., Garlanda C., Romani L., Gascan H., Bellocchio S., Bozza S., Cassatella M.A., Jeannin P., and Mantovani A. The humoral pattern recognition receptor PTX3 is stored in neutrophil granules and localizes in extracellular traps. J. Exp. Med. 204 (2007) 793-804
20. Jeannin P., Bottazzi B., Sironi M., Doni A., Rusnati M., Presta M., Maina V., Magistrelli G., Haeuw J.F., Hoeffel G., Thieblemont N., Corvaia N., Garlanda C., Delneste Y., and Mantovani A. Complexity and complementarity of outer membrane protein A recognition by cellular and humoral innate immunity receptors. Immunity 22 (2005) 551-560
21. Manfredi A.A., Rovere-Querini P., Bottazzi B., Garlanda C., and Mantovani A. Pentraxins, humoral innate immunity and tissue injury. Curr. Opin. Immunol. 20 (2008) 538-544
22. Napoleone E., Di Santo A., Bastone A., Peri G., Mantovani A., de Gaetano G., Donati M.B., and Lorenzet R. Long pentraxin PTX3 upregulates tissue factor expression in human endothelial cells: a novel link between vascular inflammation and clotting activation. Arterioscler. Thromb. Vasc. Biol. 22 (2002) 782-787
23. Nauta A.J., Bottazzi B., Mantovani A., Salvatori G., Kishore U., Schwaeble W.J., Gingras A.R., Tzima S., Vivanco F., Egido J., Tijsma O., Hack E.C., Daha M.R., and Roos A. Biochemical and functional characterization of the interaction between pentraxin 3 and C1q. Eur. J. Immunol. 33 (2003) 465-473
24. Olesen R., Wejse C., Velez D.R., Bisseye C., Sodemann M., Aaby P., Rabna P., Worwui A., Chapman H., Diatta M., Adegbola R.A., Hill P.C., Ostergaard L., Williams S.M., and Sirugo G. DC-SIGN (CD209), pentraxin 3 and vitamin D receptor gene variants associate with pulmonary tuberculosis risk in West Africans. Genes Immun. 8 (2007) 456-467
25. Paffoni A., Ragni G., Doni A., Somigliana E., Pasqualini F., Restelli L., Pardi G., Mantovani A., and Garlanda C. Follicular fluid levels of the long pentraxin PTX3. J. Soc. Gynecol. Invest. 13 (2006) 226-231
26. Pepys M.B., and Hirschfield G.M. C-reactive protein: a critical update. J. Clin. Invest. 111 (2003) 1805-1812
27. Popovici R.M., Betzler N.K., Krause M.S., Luo M., Jauckus J., Germeyer A., Bloethner S., Schlotterer A., Kumar R., Strowitzki T., and von Wolff M. Gene expression profiling of human endometrial-trophoblast interaction in a coculture model. Endocrinology 147 (2006) 5662-5675
28. Popovici R.M., Krause M.S., Jauckus J., Germeyer A., Brum I.S., Garlanda C., Strowitzki T., and von Wolff M. The long pentraxin PTX3 in human endometrium: regulation by steroids and trophoblast products. Endocrinology 149 (2008) 1136-1143
29. Presta M., Camozzi M., Salvatori G., and Rusnati M. Role of the soluble pattern recognition receptor PTX3 in vascular biology. J. Cell Mol. Med. 11 (2007) 723-738
30. Reading P.C., Bozza S., Gilbertson B., Tate M., Moretti S., Job E.R., Crouch E.C., Brooks A.G., Brown L.E., Bottazzi B., Romani L., and Mantovani A. Antiviral activity of the long chain pentraxin PTX3 against influenza viruses. J. Immunol. 180 (2008) 3391-3398
31. Redman C.W., Sacks G.P., and Sargent I.L. Preeclampsia: an excessive maternal inflammatory response to pregnancy. Am. J. Obstet. Gynecol. 180 (1999) 499-506
32. Reese J., Das S.K., Paria B.C., Lim H., Song H., Matsumoto H., Knudtson K.L., DuBois R.N., and Dey S.K. Global gene expression analysis to identify molecular markers of uterine receptivity and embryo implantation. J. Biol. Chem. 276 (2001) 44137-44145
33. Rovere-Querini P., Antonacci S., Dell'Antonio G., Angeli A., Almirante G., Cin E.D., Valsecchi L., Lanzani C., Sabbadini M.G., Doglioni C., Manfredi A.A., and Castiglioni M.T. Plasma and tissue expression of the long pentraxin 3 during normal pregnancy and preeclampsia. Obstet. Gynecol. 108 (2006) 148-155
34. Salustri A., Garlanda C., Hirsch E., De Acetis M., Maccagno A., Bottazzi B., Doni A., Bastone A., Mantovani G., Beck Peccoz P., Salvatori G., Mahoney D.J., Day A.J., Siracusa G., Romani L., and Mantovani A. PTX3 plays a key role in the organization of the cumulus oophorus extracellular matrix and in in vivo fertilization. Development 131 (2004) 1577-1586
35. Sargent I.L., Borzychowski A.M., and Redman C.W. NK cells and human pregnancy-an inflammatory view. Trends Immunol. 27 (2006) 399-404
36. Scarchilli L., Camaioni A., Bottazzi B., Negri V., Doni A., Deban L., Bastone A., Salvatori G., Mantovani A., Siracusa G., and Salustri A. PTX3 interacts with inter-{alpha}-trypsin inhibitor: implications for hyaluronan organization and cumulus oophorus expansion. J. Biol. Chem. 282 (2007) 30161-30170
37. Tranguch S., Chakrabarty A., Guo Y., Wang H., and Dey S.K. Maternal pentraxin 3 deficiency compromises implantation in mice. Biol. Reprod. 77 (2007) 425-432
38. Varani S., Elvin J.A., Yan C., DeMayo J., DeMayo F.J., Horton H.F., Byrne M.C., and Matzuk M.M. Knockout of pentraxin 3, a downstream target of growth differentiation factor-9, causes female subfertility. Mol. Endocrinol. 16 (2002) 1154-1167
39. Zhang X., Jafari N., Barnes R.B., Confino E., Milad M., and Kazer R.R. Studies of gene expression in human cumulus cells indicate pentraxin 3 as a possible marker for oocyte quality. Fertil. Steril. 83 Suppl. 1 (2005) 1169-1179