-
1
-
-
61849127705
-
Once-daily extended-release levetiracetam as adjunctive treatment of partial-onset seizures in patients with epilepsy: A double-blind, randomized, placebo-controlled trial
-
Peltola J, Coetzee C, Jiménez F, et al. Once-daily extended-release levetiracetam as adjunctive treatment of partial-onset seizures in patients with epilepsy: a double-blind, randomized, placebo-controlled trial. Epilepsia. 2009;50(3):406-414.
-
(2009)
Epilepsia
, vol.50
, Issue.3
, pp. 406-414
-
-
Peltola, J.1
Coetzee, C.2
Jiménez, F.3
-
2
-
-
0033775210
-
Efficacy and tolerability of levetiracetam 3000 mg/d in patients with refractory partial seizures: A multicenter, double-blind, responder-selected study evaluating monotherapy
-
Ben-Menachem E, Falter U. Efficacy and tolerability of levetiracetam 3000 mg/d in patients with refractory partial seizures: a multicenter, double-blind, responder-selected study evaluating monotherapy. European Levetiracetam Study Group. Epilepsia. 2000;41(10):1276-1283. (Pubitemid 30766152)
-
(2000)
Epilepsia
, vol.41
, Issue.10
, pp. 1276-1283
-
-
Ben-Menachem, E.1
Falter, U.2
-
3
-
-
0033854805
-
Levetiracetam for partial seizures: Results of a double-blind, randomized clinical trial
-
Cereghino JJ, Biton V, Abou-Khalil B, Dreifuss F, Gauer LJ, Leppik I. Levetiracetam for partial seizures: results of a double-blind, randomized clinical trial. Neurology. 2000;55(2):236-242. (Pubitemid 30604624)
-
(2000)
Neurology
, vol.55
, Issue.2
, pp. 236-242
-
-
Cereghino, J.J.1
Biton, V.2
Abou-Khalil, B.3
Dreifuss, F.4
Gauer, L.J.5
Leppik, I.6
-
4
-
-
0033811027
-
Multicenter double-blind, randomized, placebo-controlled trial of levetiracetam as add-on therapy in patients with refractory partial seizures
-
Shorvon SD, Löwenthal A, Janz D, Bielen E, Loiseau P. Multicenter double-blind, randomized, placebo-controlled trial of levetiracetam as add-on therapy in patients with refractory partial seizures. European Levetiracetam Study Group. Epilepsia. 2000;41(9):1179-1186. (Pubitemid 30692334)
-
(2000)
Epilepsia
, vol.41
, Issue.9
, pp. 1179-1186
-
-
Shorvon, S.D.1
Lowenthal, A.2
Janz, D.3
Bielen, E.4
Loiseau, P.5
-
5
-
-
64149099916
-
Pharmacokinetics of levetiracetam XR 500 mg tablets
-
Rouits E, Burton I, Guénolé E, Troenaru MM, Stockis A, Sargentini-Maier ML. Pharmacokinetics of levetiracetam XR 500 mg tablets. Epilepsy Res. 2009;84(2-3):224-231.
-
(2009)
Epilepsy Res
, vol.84
, Issue.2-3
, pp. 224-231
-
-
Rouits, E.1
Burton, I.2
Guénolé, E.3
Troenaru, M.M.4
Stockis, A.5
Sargentini-Maier, M.L.6
-
6
-
-
0028825031
-
The novel antiepileptic drug levetiracetam (ucb L059) appears to act via a specific binding site in CNS membranes
-
Noyer M, Gillard M, Matagne A, Hénichart JP, Wülfert E. The novel antiepileptic drug levetiracetam (ucb L059) appears to act via a specific binding site in CNS membranes. Eur J Pharmacol. 1995;286(2):137-146.
-
(1995)
Eur J Pharmacol
, vol.286
, Issue.2
, pp. 137-146
-
-
Noyer, M.1
Gillard, M.2
Matagne, A.3
Hénichart, J.P.4
Wülfert, E.5
-
7
-
-
0032563178
-
Evidence for a unique profile of levetiracetam in rodent models of seizures and epilepsy
-
DOI 10.1016/S0014-2999(98)00410-5, PII S0014299998004105
-
Klitgaard H, Matagne A, Gobert J, Wülfert E. Evidence for a unique profile of levetiracetam in rodent models of seizures and epilepsy. Eur J Pharmacol. 1998;353(2-3):191-206. (Pubitemid 28352266)
-
(1998)
European Journal of Pharmacology
, vol.353
, Issue.2-3
, pp. 191-206
-
-
Klitgaard, H.1
Matagne, A.2
Gobert, J.3
Wulfert, E.4
-
8
-
-
0014597998
-
A permanent change in brain function resulting from daily electrical stimulation
-
Goddard GV, McIntyre DC, Leech CK. A permanent change in brain function resulting from daily electrical stimulation. Exp Neurol. 1969;25(3):295-330.
-
(1969)
Exp Neurol
, vol.25
, Issue.3
, pp. 295-330
-
-
Goddard, G.V.1
McIntyre, D.C.2
Leech, C.K.3
-
9
-
-
47249088211
-
Anticonvulsive and antiepileptogenic effects of levetiracetam in the audiogenic kindling model
-
Vinogradova LV, van Rijn CM. Anticonvulsive and antiepileptogenic effects of levetiracetam in the audiogenic kindling model. Epilepsia. 2008;49(7):1160-1168.
-
(2008)
Epilepsia
, vol.49
, Issue.7
, pp. 1160-1168
-
-
Vinogradova, L.V.1
Van Rijn, C.M.2
-
10
-
-
0031908063
-
Antiepileptogenic effects of the novel anticonvulsant levetiracetam (ucb L059)in the kindling model of temporal lobe epilepsy
-
Löscher W, Hönack D, Rundfeldt C. Antiepileptogenic effects of the novel anticonvulsant levetiracetam (ucb L059) in the kindling model of temporal lobe epilepsy. J Pharmacol Exp Ther. 1998;284(2):474-479. (Pubitemid 28086631)
-
(1998)
Journal of Pharmacology and Experimental Therapeutics
, vol.284
, Issue.2
, pp. 474-479
-
-
Loscher, W.1
Honack, D.2
Rundfeldt, C.3
-
11
-
-
26944485922
-
Long-lasting antiepileptic effects of levetiracetam against epileptic seizures in the spontaneously epileptic rat (SER): Differentiation of levetiracetam from conventional antiepileptic drugs
-
DOI 10.1111/j.1528-1167.2005.29604.x
-
Ji-qun C, Ishihara K, Nagayama T, Serikawa T, Sasa M. Long-lasting antiepileptic effects of levetiracetam against epileptic seizures in the spontaneously epileptic rat (SER): differentiation of levetiracetam from conventional antiepileptic drugs. Epilepsia. 2005;46(9):1362-1370. (Pubitemid 43919474)
-
(2005)
Epilepsia
, vol.46
, Issue.9
, pp. 1362-1370
-
-
Ji-Qun, C.1
Ishihara, K.2
Nagayama, T.3
Serikawa, T.4
Sasa, M.5
-
12
-
-
0034883899
-
2+ currents
-
DOI 10.1053/seiz.2000.0504
-
Zona C, Niespodziany I, Marchetti C, Klitgaard H, Bernardi G, Margineanu DG. Levetiracetam does not modulate neuronal voltage-gated Na+ and T-type Ca2+ currents. Seizure. 2001;10(4):279-286. (Pubitemid 32705452)
-
(2001)
Seizure
, vol.10
, Issue.4
, pp. 279-286
-
-
Zona, C.1
Niespodziany, I.2
Marchetti, C.3
Klitgaard, H.4
Bernardi, G.5
Margineanu, D.G.6
-
13
-
-
0036193683
-
Selective blockade of N-type calcium channels by levetiracetam
-
DOI 10.1046/j.1528-1157.2002.24501.x
-
Lukyanetz EA, Shkryl VM, Kostyuk PG. Selective blockade of N-type calcium channels by levetiracetam. Epilepsia. 2002;43(1):9-18. (Pubitemid 34215447)
-
(2002)
Epilepsia
, vol.43
, Issue.1
, pp. 9-18
-
-
Lukyanetz, E.A.1
Shkryl, V.M.2
Kostyuk, P.G.3
-
14
-
-
0035933671
-
2+ current in pyramidal neurones of rat hippocampal slices
-
DOI 10.1016/S0304-3940(01)01884-5, PII S0304394001018845
-
Niespodziany I, Klitgaard H, Margineanu DG. Levetiracetam inhibits the high-voltage-activated Ca(2+) current in pyramidal neurones of rat hippocampal slices. Neurosci Lett. 2001;306(1-2):5-8. (Pubitemid 32524284)
-
(2001)
Neuroscience Letters
, vol.306
, Issue.1-2
, pp. 5-8
-
-
Niespodziany, I.1
Klitgaard, H.2
Margineanu, D.G.3
-
15
-
-
0345700624
-
2+ transients and epileptiform potentials in hippocampal neurons
-
Angehagen M, Margineanu DG, Ben-Menachem E, Rönnbäck L, Hansson E, Klitgaard H. Levetiracetam reduces caffeine-induced Ca2+ transients and epileptiform potentials in hippocampal neurons. Neuroreport. 2003;14(3):471-475. (Pubitemid 36337953)
-
(2003)
NeuroReport
, vol.14
, Issue.3
, pp. 471-475
-
-
Angehagen, M.1
Margineanu, D.G.2
Ben-Menachem, E.3
Ronnback, L.4
Hansson, E.5
Klitgaard, H.6
-
16
-
-
43049148382
-
Levetiracetam inhibits both ryanodine and IP3 receptor activated calcium induced calcium release in hippocampal neurons in culture
-
Nagarkatti N, Deshpande LS, DeLorenzo RJ. Levetiracetam inhibits both ryanodine and IP3 receptor activated calcium induced calcium release in hippocampal neurons in culture. Neurosci Lett. 2008;436(3):289-293.
-
(2008)
Neurosci Lett
, vol.436
, Issue.3
, pp. 289-293
-
-
Nagarkatti, N.1
Deshpande, L.S.2
DeLorenzo, R.J.3
-
17
-
-
0025918695
-
Caffeine-induced Ca2+ release inhibits GABAA responsiveness in rat identified native primary afferents
-
Desaulles E, Boux O, Feltz P. Caffeine-induced Ca2+ release inhibits GABAA responsiveness in rat identified native primary afferents. Eur J Pharmacol. 1991;203(1):137-140.
-
(1991)
Eur J Pharmacol
, vol.203
, Issue.1
, pp. 137-140
-
-
Desaulles, E.1
Boux, O.2
Feltz, P.3
-
18
-
-
0033800837
-
Inhibition of neuronal hypersynchrony in vitro differentiates levetiracetam from classical antiepileptic drugs
-
DOI 10.1006/phrs.2000.0689
-
Margineanu DG, Klitgaard H. Inhibition of neuronal hypersynchrony in vitro differentiates levetiracetam from classical antiepileptic drugs. Pharmacol Res. 2000;42(4):281-285. (Pubitemid 30743409)
-
(2000)
Pharmacological Research
, vol.42
, Issue.4
, pp. 281-285
-
-
Georg Margineanu, D.1
Klitgaard, H.2
-
19
-
-
3042748137
-
The synaptic vesicle is the protein SV2A is the binding site for the antiepileptic drug levetiracetam
-
DOI 10.1073/pnas.0308208101
-
Lynch BA, Lambeng N, Nocka K, et al. The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam. Proc Natl Acad Sci U S A. 2004;101(26):9861-9866. (Pubitemid 38869327)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.26
, pp. 9861-9866
-
-
Lynch, B.A.1
Lambeng, N.2
Nocka, K.3
Kensel-Hammes, P.4
Bajjalieh, S.M.5
Matagne, A.6
Fuks, B.7
-
20
-
-
33645813802
-
Binding characteristics of levetiracetam to synaptic vesicle protein 2A (SV2A) in human brain and in CHO cells expressing the human recombinant protein
-
Gillard M, Chatelain P, Fuks B. Binding characteristics of levetiracetam to synaptic vesicle protein 2A (SV2A) in human brain and in CHO cells expressing the human recombinant protein. Eur J Pharmacol. 2006;536(1-2):102-108.
-
(2006)
Eur J Pharmacol
, vol.536
, Issue.1-2
, pp. 102-108
-
-
Gillard, M.1
Chatelain, P.2
Fuks, B.3
-
21
-
-
0033592991
-
Abnormal neurotransmission in mice lacking synaptic vesicle protein 2A (SV2A)
-
Crowder KM, Gunther JM, Jones TA, et al. Abnormal neurotransmission in mice lacking synaptic vesicle protein 2A (SV2A). Proc Natl Acad Sci U S A. 1999;96(26):15268-15273.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, Issue.26
, pp. 15268-15273
-
-
Crowder, K.M.1
Gunther, J.M.2
Jones, T.A.3
-
22
-
-
70449700819
-
-
Smyrna, GA: UCB Pharma, Inc
-
Keppra XR [Package insert]. Smyrna, GA: UCB Pharma, Inc, 2008.
-
(2008)
Keppra XR [Package Insert]
-
-
-
23
-
-
4344639324
-
Clinical pharmacokinetics of levetiracetam
-
Patsalos PN. Clinical pharmacokinetics of levetiracetam. Clin Pharmacokinet. 2004;43(11):707-724.
-
(2004)
Clin Pharmacokinet
, vol.43
, Issue.11
, pp. 707-724
-
-
Patsalos, P.N.1
-
24
-
-
0033621925
-
Pharmacokinetic profile of levetiracetam: Toward ideal characteristics
-
Patsalos PN. Pharmacokinetic profile of levetiracetam: toward ideal characteristics. Pharmacol Ther. 2000;85(2):77-85.
-
(2000)
Pharmacol Ther
, vol.85
, Issue.2
, pp. 77-85
-
-
Patsalos, P.N.1
-
25
-
-
20444458809
-
Pharmacokinetics of levetiracetam in patients with moderate to severe liver cirrhosis (Child-Pugh classes A, B, and C): Characterization by dynamic liver function tests
-
DOI 10.1016/j.clpt.2005.02.003, PII S0009923605000937
-
Brockmöller J, Thomsen T, Wittstock M, Coupez R, Lochs H, Roots I. Pharmacokinetics of levetiracetam in patients with moderate to severe liver cirrhosis (Child-Pugh classes A, B, and C): characterization by dynamic liver function tests. Clin Pharmacol Ther. 2005;77(6):529-541. (Pubitemid 40824966)
-
(2005)
Clinical Pharmacology and Therapeutics
, vol.77
, Issue.6
, pp. 529-541
-
-
Brockmoller, J.1
Thomsen, T.2
Wittstock, M.3
Coupez, R.4
Lochs, H.5
Roots, I.6
-
26
-
-
34249807897
-
Pharmacokinetics of levetiracetam in infants and young children with epilepsy
-
DOI 10.1111/j.1528-1167.2007.01090.x
-
Glauser TA, Mitchell WG, Weinstock A, et al. Pharmacokinetics of levetiracetam in infants and young children with epilepsy. Epilepsia. 2007;48(6):1117-1122. (Pubitemid 46854880)
-
(2007)
Epilepsia
, vol.48
, Issue.6
, pp. 1117-1122
-
-
Glauser, T.A.1
Mitchell, W.G.2
Weinstock, A.3
Bebin, M.4
Chen, D.5
Coupez, R.6
Stockis, A.7
Lu, Z.8
-
27
-
-
0035675738
-
Pharmacokinetic study of levetiracetam in children
-
Pellock JM, Glauser TA, Bebin EM, et al. Pharmacokinetic study of levetiracetam in children. Epilepsia. 2001;42(12):1574-1579.
-
(2001)
Epilepsia
, vol.42
, Issue.12
, pp. 1574-1579
-
-
Pellock, J.M.1
Glauser, T.A.2
Bebin, E.M.3
-
28
-
-
0033663648
-
Absence of pharmacokinetic drug interaction of levetiracetam with phenytoin in patients with epilepsy determined by new technique
-
Browne TR, Szabo GK, Leppik IE, Josephs E, Paz J, Baltes E, Jensen CM. Absence of pharmacokinetic drug interaction of levetiracetam with phenytoin in patients with epilepsy determined by new technique. J Clin Pharmacol. 2000;40(6):590-595.
-
(2000)
J Clin Pharmacol
, vol.40
, Issue.6
, pp. 590-595
-
-
Browne, T.R.1
Szabo, G.K.2
Leppik, I.E.3
Josephs, E.4
Paz, J.5
Baltes, E.6
Jensen, C.M.7
-
29
-
-
0034757376
-
Lack of effect of repeated administration of levetiracetam on the pharmacodynamic and pharmacokinetic profiles of warfarin
-
DOI 10.1016/S0920-1211(01)00293-5, PII S0920121101002935
-
Ragueneau-Majlessi I, Levy RH, Meyerhoff C. Lack of effect of repeated administration of levetiracetam on the pharmacodynamic and pharmacokinetic profiles of warfarin. Epilepsy Res. 2001;47(1-2):55-63. (Pubitemid 32973648)
-
(2001)
Epilepsy Research
, vol.47
, Issue.1-2
, pp. 55-63
-
-
Ragueneau-Majlessi, I.1
Levy, R.H.2
Meyerhoff, C.3
-
30
-
-
0034900762
-
Repeated administration of the novel antiepileptic agent levetiracetam does not alter digoxin pharmacokinetics and pharmacodynamics in healthy volunteers
-
DOI 10.1016/S0920-1211(01)00253-4, PII S0920121101002534
-
Levy RH, Ragueneau-Majlessi I, Baltes E. Repeated administration of the novel antiepileptic agent levetiracetam does not alter digoxin pharmacokinetics and pharmacodynamics in healthy volunteers. Epilepsy Res. 2001;46(2):93-99. (Pubitemid 32709922)
-
(2001)
Epilepsy Research
, vol.46
, Issue.2
, pp. 93-99
-
-
Levy, R.H.1
Ragueneau-Majlessi, I.2
Baltes, E.3
-
31
-
-
0036062267
-
Levetiracetam does not alter the pharmacokinetics of an oral contraceptive in healthy women
-
DOI 10.1046/j.1528-1157.2002.57701.x
-
Ragueneau-Majlessi I, Levy RH, Janik F. Levetiracetam does not alter the pharmacokinetics of an oral contraceptive in healthy women. Epilepsia. 2002;43(7):697:702. (Pubitemid 34774250)
-
(2002)
Epilepsia
, vol.43
, Issue.7
, pp. 697-702
-
-
Ragueneau-Majlessi, I.1
Levy, R.H.2
Janik, F.3
-
32
-
-
19444366567
-
Effect of levetiracetam on the pharmacokinetics of adjunctive antiepileptic drugs: A pooled analysis of data from randomized clinical trials
-
DOI 10.1016/j.eplepsyres.2005.01.005, PII S0920121105000252
-
Gidal BE, Baltès E, Otoul C, Perucca E. Effect of levetiracetam on the pharmacokinetics of adjunctive antiepileptic drugs: a pooled analysis of data from randomized clinical trials. Epilepsy Res. 2005;64(1-2):1-11. (Pubitemid 40726160)
-
(2005)
Epilepsy Research
, vol.64
, Issue.1-2
, pp. 1-11
-
-
Gidal, B.E.1
Baltes, E.2
Otoul, C.3
Perucca, E.4
-
33
-
-
12244269686
-
Effects of antiepileptic comedication on levetiracetam pharmacokinetics: A pooled analysis of data from randomized adjunctive therapy trials
-
DOI 10.1016/S0920-1211(02)00250-4
-
Perucca E, Gidal BE, Baltès E. Effects of antiepileptic comedication on levetiracetam pharmacokinetics: a pooled analysis of data from randomized adjunctive therapy trials. Epilepsy Res. 2003;53(1-2):47-56. (Pubitemid 36170170)
-
(2003)
Epilepsy Research
, vol.53
, Issue.1-2
, pp. 47-56
-
-
Perucca, E.1
Gidal, B.E.2
Baltes, E.3
-
34
-
-
33745665605
-
Double-blind placebo-controlled trial of adjunctive levetiracetam in pediatric partial seizures
-
DOI 10.1212/01.wnl.0000217916.00225.3a, PII 0000611420060613000011
-
Glauser TA, Ayala R, Elterman RD, et al. Double-blind placebo-controlled trial of adjunctive levetiracetam in pediatric partial seizures. Neurology. 2006;66(11):1654-1660. (Pubitemid 43964617)
-
(2006)
Neurology
, vol.66
, Issue.11
, pp. 1654-1660
-
-
Glauser, T.A.1
Ayala, R.2
Elterman, R.D.3
Mitchell, W.G.4
Van Orman, C.B.5
Gauer, L.J.6
Lu, Z.7
-
35
-
-
0036091188
-
Efficacy and safety of levetiracetam in children with partial seizures: An open-label trial
-
Glauser TA, Pellock JM, Bebin EM, et al. Efficacy and safety of levetiracetam in children with partial seizures: an open-label trial. Epilepsia. 2002;43(5):518-524.
-
(2002)
Epilepsia
, vol.43
, Issue.5
, pp. 518-524
-
-
Glauser, T.A.1
Pellock, J.M.2
Bebin, E.M.3
-
36
-
-
21044451709
-
Efficacy and safety of levetiracetam: An add-on trial in children with refractory epilepsy
-
DOI 10.1016/j.seizure.2005.02.004, PII S1059131105000373
-
Grosso S, Franzoni E, Coppola G, et al. Efficacy and safety of levetiracetam: an add-on trial in children with refractory epilepsy. Seizure. 2005;14(4):248-253. (Pubitemid 40704329)
-
(2005)
Seizure
, vol.14
, Issue.4
, pp. 248-253
-
-
Grosso, S.1
Franzoni, E.2
Coppola, G.3
Iannetti, P.4
Verrotti, A.5
Cordelli, D.M.6
Marchiani, V.7
Pascotto, A.8
Spalice, A.9
Acampora, B.10
Morgese, G.11
Balestri, P.12
-
37
-
-
12144253720
-
Clinical experience with levetiracetam in childhood epilepsy: An add-on and mono-therapy trial
-
DOI 10.1016/j.seizure.2004.10.004, PII S1059131104001888
-
Lagae L, Buyse G, Ceulemans B. Clinical experience with levetiracetam in childhood epilepsy: an add-on and mono-therapy trial. Seizure. 2005;14(1):66-71. (Pubitemid 40103960)
-
(2005)
Seizure
, vol.14
, Issue.1
, pp. 66-71
-
-
Lagae, L.1
Buyse, G.2
Ceulemans, B.3
-
38
-
-
43749107871
-
Add-on levetiracetam in children and adolescents with refractory epilepsy: Results of an open-label multi-centre study
-
Callenbach PM, Arts WF, ten Houten R, et al. Add-on levetiracetam in children and adolescents with refractory epilepsy: results of an open-label multi-centre study. Eur J Paediatr Neurol. 2008;12(4):321-327.
-
(2008)
Eur J Paediatr Neurol
, vol.12
, Issue.4
, pp. 321-327
-
-
Callenbach, P.M.1
Arts, W.F.2
Ten Houten, R.3
-
39
-
-
39749166363
-
Levetiracetam for the treatment of idiopathic generalized epilepsy with myoclonic seizures
-
DOI 10.1212/01.wnl.0000297512.18364.40, PII 0000611420080219000006
-
Noachtar S, Andermann E, Meyvisch P, et al. Levetiracetam for the treatment of idiopathic generalized epilepsy with myoclonic seizures. Neurology. 2008;70(8):607-616. (Pubitemid 351294638)
-
(2008)
Neurology
, vol.70
, Issue.8
, pp. 607-616
-
-
Noachtar, S.1
Andermann, E.2
Meyvisch, P.3
Andermann, F.4
Gough, W.B.5
Schiemann-Delgado, J.6
-
40
-
-
35848938482
-
Placebo-controlled study of levetiracetam in idiopathic generalized epilepsy
-
Levetiracetam N01057 Study Group
-
Berkovic SF, Knowlton RC, Leroy RF, Schiemann J, Falter U; Levetiracetam N01057 Study Group. Placebo-controlled study of levetiracetam in idiopathic generalized epilepsy. Neurology. 2007;69(18):1751-1760.
-
(2007)
Neurology
, vol.69
, Issue.18
, pp. 1751-1760
-
-
Berkovic, S.F.1
Knowlton, R.C.2
Leroy, R.F.3
Schiemann, J.4
Falter, U.5
-
41
-
-
39749190684
-
Levetiracetam: Past, present and future
-
Safdieh J, Harden C. Levetiracetam: past, present and future. Future Medicine. 2006;1(4):365-371.
-
(2006)
Future Medicine
, vol.1
, Issue.4
, pp. 365-371
-
-
Safdieh, J.1
Harden, C.2
-
42
-
-
33846850154
-
Comparison of levetiracetam and controlled-release carbamazepine in newly diagnosed epilepsy
-
Levetiracetam Monotherapy Study Group
-
Brodie MJ, Perucca E, Ryvlin P, Ben-Menachem E, Meencke HJ; Levetiracetam Monotherapy Study Group. Comparison of levetiracetam and controlled-release carbamazepine in newly diagnosed epilepsy. Neurology. 2007;68(6):402-408.
-
(2007)
Neurology
, vol.68
, Issue.6
, pp. 402-408
-
-
Brodie, M.J.1
Perucca, E.2
Ryvlin, P.3
Ben-Menachem, E.4
Meencke, H.J.5
-
43
-
-
13444269601
-
Clinical experience of levetiracetam monotherapy for adults with epilepsy: 1-year follow-up study
-
DOI 10.1016/j.seizure.2004.12.006, PII S1059131104002286
-
Alsaadi TM, Shatzel A, Marquez AV, Jorgensen J, Farias S. Clinical experience of levetiracetam monotherapy for adults with epilepsy: 1-year follow-up study. Seizure. 2005;14(2):139-142. (Pubitemid 40214742)
-
(2005)
Seizure
, vol.14
, Issue.2
, pp. 139-142
-
-
Alsaadi, T.M.1
Shatzel, A.2
Marquez, A.V.3
Jorgensen, J.4
Farias, S.5
-
44
-
-
0942298810
-
Levetiracetam monotherapy for elderly patients with epilepsy
-
DOI 10.1016/S1059-1311(03)00070-0
-
Alsaadi TM, Koopmans S, Apperson M, Farias S. Levetiracetam monotherapy for elderly patients with epilepsy. Seizure. 2004;13(1):58-60. (Pubitemid 38139667)
-
(2004)
Seizure
, vol.13
, Issue.1
, pp. 58-60
-
-
Alsaadi, T.M.1
Koopmans, S.2
Apperson, M.3
Farias, S.4
-
45
-
-
0038474236
-
Levetiracetam nonotherapy for newly diagnosed epilepsy patients
-
DOI 10.1016/S1059-1311(02)00274-1
-
Alsaadi TM, Thieman C. Levetiracetam monotherapy for newly diagnosed epilepsy patients. Seizure. 2003;12(3):154-156. (Pubitemid 36452286)
-
(2003)
Seizure
, vol.12
, Issue.3
, pp. 154-156
-
-
Alsaadi, T.M.1
Theiman, C.2
-
46
-
-
0036815983
-
Levetiracetam monotherapy for adults with localization-related epilepsy
-
DOI 10.1016/S1525-5050(02)00516-4, PII S1525505002005164
-
Alsaadi TM, Thieman C, Zusman EE. Levetiracetam monotherapy for adults with localization-related epilepsy. Epilepsy Behav. 2002;3(5):471-474. (Pubitemid 35460417)
-
(2002)
Epilepsy and Behavior
, vol.3
, Issue.5 I
, pp. 471-474
-
-
Alsaadi, T.M.1
Thieman, C.2
Zusman, E.E.3
-
47
-
-
26444433365
-
Benefit-risk assessment of levetiracetam in the treatment of partial seizures
-
DOI 10.2165/00002018-200528100-00004
-
Abou-Khalil B. Benefit-risk assessment of levetiracetam in the treatment of partial seizures. Drug Saf. 2005;28(10):871-890. (Pubitemid 41428544)
-
(2005)
Drug Safety
, vol.28
, Issue.10
, pp. 871-890
-
-
Abou-Khalil, B.1
-
48
-
-
0034768383
-
A systematic review of the safety profile of levetiracetam: A new antiepileptic drug
-
DOI 10.1016/S0920-1211(01)00296-0, PII S0920121101002960
-
French J, Edrich P, Cramer JA. A systematic review of the safety profile of levetiracetam: a new antiepileptic drug. Epilepsy Res. 2001;47(1-2):77-90. (Pubitemid 32973650)
-
(2001)
Epilepsy Research
, vol.47
, Issue.1-2
, pp. 77-90
-
-
French, J.1
Edrich, P.2
Cramer, J.A.3
-
49
-
-
33947265900
-
Levetiracetam in clinical practice: Long-term experience in patients with refractory epilepsy referred to a tertiary epilepsy center
-
DOI 10.1016/j.yebeh.2006.11.016, PII S1525505006004677
-
Bootsma HP, Ricker L, Diepman L, et al. Levetiracetam in clinical practice: long-term experience in patients with refractory epilepsy referred to a tertiary epilepsy center. Epilepsy Behav. 2007;10(2):296-303. (Pubitemid 46432220)
-
(2007)
Epilepsy and Behavior
, vol.10
, Issue.2
, pp. 296-303
-
-
Bootsma, H.P.R.1
Ricker, L.2
Diepman, L.3
Gehring, J.4
Hulsman, J.5
Lambrechts, D.6
Leenen, L.7
Majoie, M.8
Schellekens, A.9
De Krom, M.10
Aldenkamp, A.P.11
-
50
-
-
29644432883
-
The long term retention of levetiracetam in a large cohort of patients with epilepsy
-
DOI 10.1136/jnnp.2005.064626
-
Depondt C, Yuen AW, Bell GS, et al. The long term retention of levetiracetam in a large cohort of patients with epilepsy. J Neurol Neurosurg Psychiatry. 2006;77(1):101-103. (Pubitemid 43022705)
-
(2006)
Journal of Neurology, Neurosurgery and Psychiatry
, vol.77
, Issue.1
, pp. 101-103
-
-
Depondt, C.1
Yuen, A.W.C.2
Bell, G.S.3
Mitchell, T.4
Koepp, M.J.5
Duncan, J.S.6
Sander, J.W.7
Sander, L.8
-
51
-
-
28944454399
-
Long-term efficacy of levetiracetam for partial seizures
-
DOI 10.1016/j.seizure.2005.09.003, PII S1059131105001627
-
Abou-Khalil B, Schaich L. Long-term efficacy of levetiracetam for partial seizures. Seizure. 2005;14(8):577-585. (Pubitemid 41782480)
-
(2005)
Seizure
, vol.14
, Issue.8
, pp. 577-585
-
-
Abou-Khalil, B.1
Schaich, L.2
-
52
-
-
3543126543
-
A prospective analysis of the outcome of levetiracetam in clinical practice
-
Nicolson A, Lewis SA, Smith DF. A prospective analysis of the outcome of levetiracetam in clinical practice. Neurology. 2004;63(3):568-570. (Pubitemid 39031397)
-
(2004)
Neurology
, vol.63
, Issue.3
, pp. 568-570
-
-
Nicolson, A.1
Lewis, S.A.2
Smith, D.F.3
-
53
-
-
0042836602
-
Psychiatric adverse events during levetiracetam therapy
-
Mula M, Trimble MR, Yuen A, Liu RS, Sander JW. Psychiatric adverse events during levetiracetam therapy. Neurology. 2003;61(5):704-706. (Pubitemid 37082613)
-
(2003)
Neurology
, vol.61
, Issue.5
, pp. 704-706
-
-
Mula, M.1
Trimble, M.R.2
Yuen, A.3
Liu, R.S.N.4
Sander, J.W.A.S.5
-
54
-
-
0038644777
-
A systematic review of the behavioral effects of levetiracetam in adults with epilepsy, cognitive disorders, or an anxiety disorder during clinical trials
-
DOI 10.1016/S1525-5050(03)00005-2
-
Cramer JA, De Rue K, Devinsky O, Edrich P, Trimble MR. A systematic review of the behavioral effects of levetiracetam in adults with epilepsy, cognitive disorders, or an anxiety disorder during clinical trials. Epilepsy Behav. 2003;4(2):124-132. (Pubitemid 37184583)
-
(2003)
Epilepsy and Behavior
, vol.4
, Issue.2
, pp. 124-132
-
-
Cramer, J.A.1
De Rue, K.2
Devinsky, O.3
Edrich, P.4
Trimble, M.R.5
-
55
-
-
1842788117
-
Levetiracetam in adult patients with and without learning disability: Focus on behavioral adverse effects
-
DOI 10.1016/j.yebeh.2003.12.005
-
Brodtkorb E, Klees TM, Nakken KO, Lossius R, Johannessen SI. Levetiracetam in adult patients with and without learning disability: focus on behavioral adverse effects. Epilepsy Behav. 2004;5(2):231-235. (Pubitemid 38461213)
-
(2004)
Epilepsy and Behavior
, vol.5
, Issue.2
, pp. 231-235
-
-
Brodtkorb, E.1
Klees, T.M.2
Nakken, K.O.3
Lossius, R.4
Johannessen, S.I.5
-
56
-
-
0347418143
-
Use of levetiracetam in a population of patients aged 65 years and older: A subset analysis of the KEEPER trial
-
DOI 10.1016/j.yebeh.2003.09.007
-
Ferrendelli JA, French J, Leppik I, et al. Use of levetiracetam in a population of patients aged 65 years and older: a subset analysis of the KEEPER trial. Epilepsy Behav. 2003;4(6):702-709. (Pubitemid 38035693)
-
(2003)
Epilepsy and Behavior
, vol.4
, Issue.6
, pp. 702-709
-
-
Ferrendelli, J.A.1
French, J.2
Leppik, I.3
Morrell, M.J.4
Herbeuval, A.5
Han, J.6
Magnus, L.7
-
57
-
-
0344442733
-
Tolerability of levetiracetam in elderly patients with CNS disorders
-
DOI 10.1016/j.eplepsyres.2003.08.010
-
Cramer JA, Leppik IE, Rue KD, Edrich P, Krämer G. Tolerability of levetiracetam in elderly patients with CNS disorders. Epilepsy Res. 2003;56(2-3):135-145. (Pubitemid 37474114)
-
(2003)
Epilepsy Research
, vol.56
, Issue.2-3
, pp. 135-145
-
-
Cramer, J.A.1
Leppik, I.E.2
De Rue, K.3
Edrich, P.4
Kramer, G.5
-
58
-
-
0142040806
-
Developmental Outcome of Levetiracetam, Its Major Metabolite in Humans, 2-Pyrrolidinone N-Butyric Acid, and Its Enantiomer (R)-alpha-ethyl-oxo- pyrrolidine Acetamide in a Mouse Model of Teratogenicity
-
DOI 10.1046/j.1528-1157.2003.21503.x
-
Isoherranen N, Spiegelstein O, Bialer M, et al. Developmental outcome of levetiracetam, its major metabolite in humans, 2-pyrrolidinone N-butyric acid, and its enantiomer (R)-alpha-ethyl-oxo-pyrrolidine acetamide in a mouse model of teratogenicity. Epilepsia. 2003;44(10):1280-1288. (Pubitemid 37280372)
-
(2003)
Epilepsia
, vol.44
, Issue.10
, pp. 1280-1288
-
-
Isoherranen, N.1
Spiegelstein, O.2
Bialer, M.3
Zhang, J.4
Merriweather, M.5
Yagen, B.6
Roeder, M.7
Triplett, A.A.8
Schurig, V.9
Finnell, R.H.10
-
59
-
-
33845405448
-
Levetiracetam in pregnancy: Preliminary experience from the UK Epilepsy and Pregnancy Register
-
DOI 10.1212/01.wnl.0000244491.48937.55, PII 0000611420061128000038
-
Hunt S, Craig J, Russell A, et al. Levetiracetam in pregnancy: preliminary experience from the UK Epilepsy and Pregnancy Register. Neurology. 2006;67(10):1876-1879. (Pubitemid 44900776)
-
(2006)
Neurology
, vol.67
, Issue.10
, pp. 1876-1879
-
-
Hunt, S.1
Craig, J.2
Russell, A.3
Guthrie, E.4
Parsons, L.5
Robertson, I.6
Waddell, R.7
Irwin, B.8
Morrison, P.J.9
Morrow, J.10
-
60
-
-
34249776676
-
Pharmacokinetics of levetiracetam during pregnancy, delivery, in the neonatal period, and lactation
-
DOI 10.1111/j.1528-1167.2007.01032.x
-
Tomson T, Palm R, Källén K, et al. Pharmacokinetics of levetiracetam during pregnancy, delivery, in the neonatal period, and lactation. Epilepsia. 2007;48(6):1111-1116. (Pubitemid 46854871)
-
(2007)
Epilepsia
, vol.48
, Issue.6
, pp. 1111-1116
-
-
Tomson, T.1
Palm, R.2
Kallen, K.3
Ben-Menachem, E.4
Soderfeldt, B.5
Danielsson, B.6
Johansson, R.7
Luef, G.8
Ohman, I.9
-
61
-
-
0025757288
-
Antiepileptogenic effects of conventional anticonvulsants in the kindling model of epilespy
-
Silver JM, Shin C, McNamara JO. Antiepileptogenic effects of conventional anticonvulsants in the kindling model of epilespy. Ann Neurol. 1991;29(4):356-363.
-
(1991)
Ann Neurol
, vol.29
, Issue.4
, pp. 356-363
-
-
Silver, J.M.1
Shin, C.2
McNamara, J.O.3
-
62
-
-
67649969652
-
Seizures beget seizures: A lack of experimental evidence and clinical relevance fails to dampen enthusiasm
-
Sills GJ. Seizures beget seizures: a lack of experimental evidence and clinical relevance fails to dampen enthusiasm. Epilepsy Curr. 2007;7(4):103-104.
-
(2007)
Epilepsy Curr
, vol.7
, Issue.4
, pp. 103-104
-
-
Sills, G.J.1
-
63
-
-
54549086060
-
Antiepileptogenesis therapy with levetiracetam: Data from kindling versus status epilepticus models
-
Dudek FE, Bertram EH, Staley KJ. Antiepileptogenesis therapy with levetiracetam: data from kindling versus status epilepticus models. Epilepsy Curr. 2008;8(1):28-30.
-
(2008)
Epilepsy Curr
, vol.8
, Issue.1
, pp. 28-30
-
-
Dudek, F.E.1
Bertram, E.H.2
Staley, K.J.3
-
64
-
-
67349218398
-
Safety and feasibility of switching from phenytoin to levetiracetam monotherapy for glioma-related seizure control following craniotomy: A randomized phase II pilot study
-
Jan 24. Epub ahead of print
-
Lim DA, Tarapore P, Chang E, et al. Safety and feasibility of switching from phenytoin to levetiracetam monotherapy for glioma-related seizure control following craniotomy: a randomized phase II pilot study. J Neurooncol. 2009 Jan 24. Epub ahead of print.
-
(2009)
J Neurooncol
-
-
Lim, D.A.1
Tarapore, P.2
Chang, E.3
-
65
-
-
0345530892
-
Levetiracetam: Preliminary experience in patients with primary brain tumours
-
Wagner GL, Wilms EB, Van Donselaar CA, Vecht ChJ. Levetiracetam: preliminary experience in patients with primary brain tumours. Seizure. 2003;12(8):585-586.
-
(2003)
Seizure
, vol.12
, Issue.8
, pp. 585-586
-
-
Wagner, G.L.1
Wilms, E.B.2
Van Donselaar, C.A.3
Vecht, Ch.J.4
-
66
-
-
0345690127
-
Levetiracetam does not alter body weight: Analysis of randomized, controlled clinical trials
-
DOI 10.1016/j.eplepsyres.2003.08.009
-
Gidal BE, Sheth RD, Magnus L, Herbeuval AF. Levetiracetam does not alter body weight: analysis of randomized, controlled clinical trials. Epilepsy Res. 2003;56(2-3):121-126. (Pubitemid 37464925)
-
(2003)
Epilepsy Research
, vol.56
, Issue.2-3
, pp. 121-126
-
-
Gidal, B.E.1
Sheth, R.D.2
Magnus, L.3
Herbeuval, A.-F.4
-
67
-
-
0034871011
-
A systematic review of the associations between dose regimens and medication compliance
-
DOI 10.1016/S0149-2918(01)80109-0
-
Claxton AJ, Cramer J, Pierce C. A systematic review of the associations between dose regimens and medication compliance. Clin Ther. 2001;23(8):1296- 1310. (Pubitemid 32804122)
-
(2001)
Clinical Therapeutics
, vol.23
, Issue.8
, pp. 1296-1310
-
-
Claxton, A.J.1
Cramer, J.2
Pierce, C.3
-
68
-
-
0024244030
-
Use of a pharmacologic indicator to compare compliance with tablets prescribed to be taken once, twice, or three times daily
-
Pullar T, Birtwell AJ, Wiles PG, Hay A, Feely MP. Use of a pharmacologic indicator to compare compliance with tablets prescribed to be taken once, twice, or three times daily. Clin Pharmacol Ther. 1988;44(5):540-545. (Pubitemid 19002867)
-
(1988)
Clinical Pharmacology and Therapeutics
, vol.44
, Issue.5
, pp. 540-545
-
-
Pullar, T.1
Birtwell, A.J.2
Wiles, P.G.3
Hay, A.4
Feely, M.P.5
-
69
-
-
34548080314
-
Extended-release formulations for the treatment of epilepsy
-
Bialer M. Extended-release formulations for the treatment of epilepsy. CNS Drugs. 2007;21(9):765-774.
-
(2007)
CNS Drugs
, vol.21
, Issue.9
, pp. 765-774
-
-
Bialer, M.1
|