-
1
-
-
37349002541
-
The biology and future prospects of antivirulence therapies
-
Cegelski L., et al. The biology and future prospects of antivirulence therapies. Nat. Rev. Microbiol. 6 (2008) 17-27
-
(2008)
Nat. Rev. Microbiol.
, vol.6
, pp. 17-27
-
-
Cegelski, L.1
-
2
-
-
33845903833
-
Drugs for bad bugs: confronting the challenges of antibacterial discovery
-
Payne D.J., et al. Drugs for bad bugs: confronting the challenges of antibacterial discovery. Nat. Rev. Drug Discov. 6 (2007) 29-40
-
(2007)
Nat. Rev. Drug Discov.
, vol.6
, pp. 29-40
-
-
Payne, D.J.1
-
3
-
-
58149295961
-
Lipoprotein biogenesis in Gram-positive bacteria: knowing when to hold 'em, knowing when to fold 'em
-
Hutchings M.I., et al. Lipoprotein biogenesis in Gram-positive bacteria: knowing when to hold 'em, knowing when to fold 'em. Trends Microbiol. 17 (2009) 13-21
-
(2009)
Trends Microbiol.
, vol.17
, pp. 13-21
-
-
Hutchings, M.I.1
-
4
-
-
38849207749
-
Stop and go: regulation of chain length in the biosynthesis of bacterial polysaccharides
-
Whitfield C., and Larue K. Stop and go: regulation of chain length in the biosynthesis of bacterial polysaccharides. Nat. Struct. Mol. Biol. 15 (2008) 121-123
-
(2008)
Nat. Struct. Mol. Biol.
, vol.15
, pp. 121-123
-
-
Whitfield, C.1
Larue, K.2
-
5
-
-
30744478198
-
Role of protein phosphorylation on serine/threonine and tyrosine in the virulence of bacterial pathogens
-
Cozzone A.J. Role of protein phosphorylation on serine/threonine and tyrosine in the virulence of bacterial pathogens. J. Mol. Microbiol. Biotechnol. 9 (2005) 198-213
-
(2005)
J. Mol. Microbiol. Biotechnol.
, vol.9
, pp. 198-213
-
-
Cozzone, A.J.1
-
6
-
-
34247325212
-
The serine/threonine/tyrosine phosphoproteome of the model bacterium Bacillus subtilis
-
Macek B., et al. The serine/threonine/tyrosine phosphoproteome of the model bacterium Bacillus subtilis. Mol. Cell. Proteomics 6 (2007) 697-707
-
(2007)
Mol. Cell. Proteomics
, vol.6
, pp. 697-707
-
-
Macek, B.1
-
7
-
-
39749166860
-
Phosphoproteome analysis of E. coli reveals evolutionary conservation of bacterial Ser/Thr/Tyr phosphorylation
-
Macek B., et al. Phosphoproteome analysis of E. coli reveals evolutionary conservation of bacterial Ser/Thr/Tyr phosphorylation. Mol. Cell. Proteomics 7 (2008) 299-307
-
(2008)
Mol. Cell. Proteomics
, vol.7
, pp. 299-307
-
-
Macek, B.1
-
8
-
-
52649125713
-
The Ser/Thr/Tyr phosphoproteome of Lactococcus lactis IL1403 reveals mutiply phosphorylated proteins
-
Soufi B., et al. The Ser/Thr/Tyr phosphoproteome of Lactococcus lactis IL1403 reveals mutiply phosphorylated proteins. Proteomics 8 (2008) 3486-3492
-
(2008)
Proteomics
, vol.8
, pp. 3486-3492
-
-
Soufi, B.1
-
9
-
-
66449094321
-
Ser/Thr/Tyr phosphoproteome analysis of pathogenic and non-pathogenic Pseudomonas species
-
Ravichandran A., et al. Ser/Thr/Tyr phosphoproteome analysis of pathogenic and non-pathogenic Pseudomonas species. Proteomics 9 (2009) 1-12
-
(2009)
Proteomics
, vol.9
, pp. 1-12
-
-
Ravichandran, A.1
-
10
-
-
45849125779
-
Structural basis for the regulation mechanism of the tyrosine kinase CapB from Staphylococcus aureus
-
Olivares-Illana V., et al. Structural basis for the regulation mechanism of the tyrosine kinase CapB from Staphylococcus aureus. PLoS Biol. 6 (2008) e143
-
(2008)
PLoS Biol.
, vol.6
-
-
Olivares-Illana, V.1
-
11
-
-
47049095612
-
Structure of Escherichia coli tyrosine kinase Etk reveals a novel activation mechanism
-
Lee D.C., et al. Structure of Escherichia coli tyrosine kinase Etk reveals a novel activation mechanism. EMBO J. 27 (2008) 1758-1766
-
(2008)
EMBO J.
, vol.27
, pp. 1758-1766
-
-
Lee, D.C.1
-
12
-
-
0018265453
-
Evidence for protein kinase activities in the prokaryote Salmonella typhimurium
-
Wang J.Y., and Koshland Jr. D.E. Evidence for protein kinase activities in the prokaryote Salmonella typhimurium. J. Biol. Chem. 253 (1978) 7605-7608
-
(1978)
J. Biol. Chem.
, vol.253
, pp. 7605-7608
-
-
Wang, J.Y.1
Koshland Jr., D.E.2
-
13
-
-
0018574976
-
Analysis of the protein-kinase activity of Escherichia coli cells
-
Manai M., and Cozzone A.J. Analysis of the protein-kinase activity of Escherichia coli cells. Biochem. Biophys. Res. Commun. 91 (1979) 819-826
-
(1979)
Biochem. Biophys. Res. Commun.
, vol.91
, pp. 819-826
-
-
Manai, M.1
Cozzone, A.J.2
-
14
-
-
0037005989
-
Protein kinases and protein phosphatases in prokaryotes: a genomic perspective
-
Kennelly P.J. Protein kinases and protein phosphatases in prokaryotes: a genomic perspective. FEMS Microbiol. Lett. 206 (2002) 1-8
-
(2002)
FEMS Microbiol. Lett.
, vol.206
, pp. 1-8
-
-
Kennelly, P.J.1
-
15
-
-
33845626641
-
How phosphotransferase system-related protein phosphorylation regulates carbohydrate metabolism in bacteria
-
Deutscher J., et al. How phosphotransferase system-related protein phosphorylation regulates carbohydrate metabolism in bacteria. Microbiol. Mol. Biol. Rev. 70 (2006) 939-1031
-
(2006)
Microbiol. Mol. Biol. Rev.
, vol.70
, pp. 939-1031
-
-
Deutscher, J.1
-
16
-
-
44449112421
-
Specificity in two-component signal transduction pathways
-
Laub M.T., and Goulian M. Specificity in two-component signal transduction pathways. Annu. Rev. Genet. 41 (2007) 121-145
-
(2007)
Annu. Rev. Genet.
, vol.41
, pp. 121-145
-
-
Laub, M.T.1
Goulian, M.2
-
17
-
-
22544465251
-
Structure and activity of the atypical serine kinase Rio1
-
LaRonde-LeBlanc N., et al. Structure and activity of the atypical serine kinase Rio1. FEBS J. 272 (2005) 3698-3713
-
(2005)
FEBS J.
, vol.272
, pp. 3698-3713
-
-
LaRonde-LeBlanc, N.1
-
18
-
-
0031782955
-
Regulation of acetate metabolism by protein phosphorylation in enteric bacteria
-
Cozzone A.J. Regulation of acetate metabolism by protein phosphorylation in enteric bacteria. Annu. Rev. Microbiol. 52 (1998) 127-164
-
(1998)
Annu. Rev. Microbiol.
, vol.52
, pp. 127-164
-
-
Cozzone, A.J.1
-
19
-
-
27944433764
-
The RsbRST stress module in bacteria: a signalling system that may interact with different output modules
-
Pané-Farré J., et al. The RsbRST stress module in bacteria: a signalling system that may interact with different output modules. J. Mol. Microbiol. Biotechnol. 9 (2005) 65-76
-
(2005)
J. Mol. Microbiol. Biotechnol.
, vol.9
, pp. 65-76
-
-
Pané-Farré, J.1
-
20
-
-
0033887436
-
A tale of two components: a novel kinase and a regulatory switch
-
Robinson V.L., et al. A tale of two components: a novel kinase and a regulatory switch. Nat. Struct. Biol. 7 (2000) 626-633
-
(2000)
Nat. Struct. Biol.
, vol.7
, pp. 626-633
-
-
Robinson, V.L.1
-
21
-
-
34247529468
-
ExoR is genetically coupled to the ExoS-ChvI two-component system and located in the periplasm of Sinorhizobium meliloti
-
Wells D.H., et al. ExoR is genetically coupled to the ExoS-ChvI two-component system and located in the periplasm of Sinorhizobium meliloti. Mol. Microbiol. 64 (2007) 647-664
-
(2007)
Mol. Microbiol.
, vol.64
, pp. 647-664
-
-
Wells, D.H.1
-
22
-
-
33846987910
-
Crystal structure of a novel prokaryotic Ser/Thr kinase and its implication in the Cpx stress response pathway
-
Zheng J., et al. Crystal structure of a novel prokaryotic Ser/Thr kinase and its implication in the Cpx stress response pathway. Mol. Microbiol. 63 (2007) 1360-1371
-
(2007)
Mol. Microbiol.
, vol.63
, pp. 1360-1371
-
-
Zheng, J.1
-
23
-
-
62449179440
-
Threonine phosphorylation prevents promoter DNA binding of the Group B Streptococcus response regulator CovR
-
Lin W.J., et al. Threonine phosphorylation prevents promoter DNA binding of the Group B Streptococcus response regulator CovR. Mol. Microbiol. 71 (2009) 1477-1495
-
(2009)
Mol. Microbiol.
, vol.71
, pp. 1477-1495
-
-
Lin, W.J.1
-
24
-
-
40349097955
-
A direct link between carbohydrate utilization and virulence in the major human pathogen group A Streptococcus
-
Shelburne III S.A., et al. A direct link between carbohydrate utilization and virulence in the major human pathogen group A Streptococcus. Proc. Natl. Acad. Sci. U. S. A. 105 (2008) 1698-1703
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 1698-1703
-
-
Shelburne III, S.A.1
-
25
-
-
33645881935
-
Regulation of bacterial virulence by two-component systems
-
Beier D., and Gross R. Regulation of bacterial virulence by two-component systems. Curr. Opin. Microbiol. 9 (2006) 143-152
-
(2006)
Curr. Opin. Microbiol.
, vol.9
, pp. 143-152
-
-
Beier, D.1
Gross, R.2
-
26
-
-
0036790373
-
Two-component and phosphorelay signal-transduction systems as therapeutic targets
-
Stephenson K., and Hoch J.A. Two-component and phosphorelay signal-transduction systems as therapeutic targets. Curr. Opin. Pharmacol. 2 (2002) 507-512
-
(2002)
Curr. Opin. Pharmacol.
, vol.2
, pp. 507-512
-
-
Stephenson, K.1
Hoch, J.A.2
-
27
-
-
50149111428
-
Targeting QseC signaling and virulence for antibiotic development
-
Rasko D.A., et al. Targeting QseC signaling and virulence for antibiotic development. Science 321 (2008) 1078-1080
-
(2008)
Science
, vol.321
, pp. 1078-1080
-
-
Rasko, D.A.1
-
28
-
-
33750326113
-
The love-hate relationship between bacterial polysaccharides and the host immune system
-
Mazmanian S.K., and Kasper D.L. The love-hate relationship between bacterial polysaccharides and the host immune system. Nat. Rev. Immunol. 6 (2006) 849-858
-
(2006)
Nat. Rev. Immunol.
, vol.6
, pp. 849-858
-
-
Mazmanian, S.K.1
Kasper, D.L.2
-
29
-
-
42549169101
-
The importance of the group A Streptococcus capsule in the pathogenesis of human infections: a historical perspective
-
Stollerman G.H., and Dale J.B. The importance of the group A Streptococcus capsule in the pathogenesis of human infections: a historical perspective. Clin. Infect. Dis. 46 (2008) 1038-1045
-
(2008)
Clin. Infect. Dis.
, vol.46
, pp. 1038-1045
-
-
Stollerman, G.H.1
Dale, J.B.2
-
30
-
-
0030604705
-
Autophosphorylation of a bacterial protein at tyrosine
-
Duclos B., et al. Autophosphorylation of a bacterial protein at tyrosine. J. Mol. Biol. 259 (1996) 891-895
-
(1996)
J. Mol. Biol.
, vol.259
, pp. 891-895
-
-
Duclos, B.1
-
31
-
-
33846683630
-
Tyrosine phosphorylation: an emerging regulatory device of bacterial physiology
-
Grangeasse C., et al. Tyrosine phosphorylation: an emerging regulatory device of bacterial physiology. Trends Biochem. Sci. 32 (2007) 86-94
-
(2007)
Trends Biochem. Sci.
, vol.32
, pp. 86-94
-
-
Grangeasse, C.1
-
32
-
-
54949108269
-
Identification of the idiosyncratic bacterial tyrosine kinase (BY-kinase) family signature
-
Jadeau F., et al. Identification of the idiosyncratic bacterial tyrosine kinase (BY-kinase) family signature. Bioinformatics 24 (2008) 2427-2430
-
(2008)
Bioinformatics
, vol.24
, pp. 2427-2430
-
-
Jadeau, F.1
-
33
-
-
33847037161
-
Influence of tyrosine-kinase Wzc activity on colanic acid production in Escherichia coli K12 cells
-
Obadia B., et al. Influence of tyrosine-kinase Wzc activity on colanic acid production in Escherichia coli K12 cells. J. Mol. Biol. 367 (2007) 42-53
-
(2007)
J. Mol. Biol.
, vol.367
, pp. 42-53
-
-
Obadia, B.1
-
34
-
-
0035951884
-
Phosphorylation of Wzc, a tyrosine autokinase, is essential for assembly of group 1 capsular polysaccharides in Escherichia coli
-
Wugeditsch T., et al. Phosphorylation of Wzc, a tyrosine autokinase, is essential for assembly of group 1 capsular polysaccharides in Escherichia coli. J. Biol. Chem. 276 (2001) 2361-2371
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 2361-2371
-
-
Wugeditsch, T.1
-
35
-
-
2442673903
-
The effect that mutations in the conserved capsular polysaccharide biosynthesis genes cpsA, cpsB, and cpsD have on virulence of Streptococcus pneumoniae
-
Morona J.K., et al. The effect that mutations in the conserved capsular polysaccharide biosynthesis genes cpsA, cpsB, and cpsD have on virulence of Streptococcus pneumoniae. J. Infect. Dis. 189 (2004) 1905-1913
-
(2004)
J. Infect. Dis.
, vol.189
, pp. 1905-1913
-
-
Morona, J.K.1
-
36
-
-
49249093047
-
A Porphyromonas gingivalis tyrosine phosphatase is a multifunctional regulator of virulence attributes
-
Maeda K., et al. A Porphyromonas gingivalis tyrosine phosphatase is a multifunctional regulator of virulence attributes. Mol. Microbiol. 69 (2008) 1153-1164
-
(2008)
Mol. Microbiol.
, vol.69
, pp. 1153-1164
-
-
Maeda, K.1
-
37
-
-
0141625244
-
Transmembrane modulator-dependent bacterial tyrosine kinase activates UDP-glucose dehydrogenases
-
Mijakovic I., et al. Transmembrane modulator-dependent bacterial tyrosine kinase activates UDP-glucose dehydrogenases. EMBO J. 22 (2003) 4709-4718
-
(2003)
EMBO J.
, vol.22
, pp. 4709-4718
-
-
Mijakovic, I.1
-
38
-
-
0141574316
-
Autophosphorylation of the Escherichia coli protein kinase Wzc regulates tyrosine phosphorylation of Ugd, a UDP-glucose dehydrogenase
-
Grangeasse C., et al. Autophosphorylation of the Escherichia coli protein kinase Wzc regulates tyrosine phosphorylation of Ugd, a UDP-glucose dehydrogenase. J. Biol. Chem. 278 (2003) 39323-39329
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 39323-39329
-
-
Grangeasse, C.1
-
39
-
-
38449099650
-
UDP-acetyl-mannosamine dehydrogenase is an endogenous protein substrate of Staphylococcus aureus protein-tyrosine kinase activity
-
Soulat D., et al. UDP-acetyl-mannosamine dehydrogenase is an endogenous protein substrate of Staphylococcus aureus protein-tyrosine kinase activity. J. Mol. Microbiol. Biotechnol. 13 (2007) 45-54
-
(2007)
J. Mol. Microbiol. Biotechnol.
, vol.13
, pp. 45-54
-
-
Soulat, D.1
-
40
-
-
33846919052
-
Control of EpsE, the phosphoglycosyltransferase initiating exopolysaccharide synthesis in Streptococcus thermophilus, by EpsD tyrosine kinase
-
Minic Z., et al. Control of EpsE, the phosphoglycosyltransferase initiating exopolysaccharide synthesis in Streptococcus thermophilus, by EpsD tyrosine kinase. J. Bacteriol. 189 (2007) 1351-1357
-
(2007)
J. Bacteriol.
, vol.189
, pp. 1351-1357
-
-
Minic, Z.1
-
41
-
-
14644398001
-
Characterization of a eukaryotic type serine/threonine protein kinase and protein phosphatase of Streptococcus pneumoniae and identification of kinase substrates
-
Novakova L., et al. Characterization of a eukaryotic type serine/threonine protein kinase and protein phosphatase of Streptococcus pneumoniae and identification of kinase substrates. FEBS J. 272 (2005) 1243-1254
-
(2005)
FEBS J.
, vol.272
, pp. 1243-1254
-
-
Novakova, L.1
-
42
-
-
59149103351
-
PknB-mediated phosphorylation of a novel substrate, N-acetylglucosamine-1-phosphate uridyltransferase, modulates its acetyltransferase activity
-
Parikh A., et al. PknB-mediated phosphorylation of a novel substrate, N-acetylglucosamine-1-phosphate uridyltransferase, modulates its acetyltransferase activity. J. Mol. Biol. 386 (2009) 451-464
-
(2009)
J. Mol. Biol.
, vol.386
, pp. 451-464
-
-
Parikh, A.1
-
43
-
-
33745283362
-
EmbR, a regulatory protein with ATPase activity, is a substrate of multiple serine/threonine kinases and phosphatase in Mycobacterium tuberculosis
-
Sharma K., et al. EmbR, a regulatory protein with ATPase activity, is a substrate of multiple serine/threonine kinases and phosphatase in Mycobacterium tuberculosis. FEBS J. 273 (2006) 2711-2721
-
(2006)
FEBS J.
, vol.273
, pp. 2711-2721
-
-
Sharma, K.1
-
44
-
-
33749570515
-
The condensing activities of the Mycobacterium tuberculosis type II fatty acid synthase are differentially regulated by phosphorylation
-
Molle V., et al. The condensing activities of the Mycobacterium tuberculosis type II fatty acid synthase are differentially regulated by phosphorylation. J. Biol. Chem. 281 (2006) 30094-30103
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 30094-30103
-
-
Molle, V.1
-
45
-
-
33847045538
-
Novel substrates of Mycobacterium tuberculosis PknH Ser/Thr kinase
-
Zheng X., et al. Novel substrates of Mycobacterium tuberculosis PknH Ser/Thr kinase. Biochem. Biophys. Res. Comm. 355 (2007) 162-168
-
(2007)
Biochem. Biophys. Res. Comm.
, vol.355
, pp. 162-168
-
-
Zheng, X.1
-
46
-
-
33847675357
-
A eukaryotic-type Ser/Thr kinase in Enterococcus faecalis mediates antimicrobial resistance and intestinal persistence
-
Kristich C.J., et al. A eukaryotic-type Ser/Thr kinase in Enterococcus faecalis mediates antimicrobial resistance and intestinal persistence. Proc. Natl. Acad. Sci. U. S. A. 104 (2007) 3508-3513
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 3508-3513
-
-
Kristich, C.J.1
-
47
-
-
25444476788
-
Yersinia outer proteins: role in modulation of host cell signaling responses and pathogenesis
-
Viboud G.I., and Bliska J.B. Yersinia outer proteins: role in modulation of host cell signaling responses and pathogenesis. Annu. Rev. Microbiol. 59 (2005) 69-89
-
(2005)
Annu. Rev. Microbiol.
, vol.59
, pp. 69-89
-
-
Viboud, G.I.1
Bliska, J.B.2
-
48
-
-
33947210792
-
Enteropathogenic Escherichia coli Tir is an SH2/3 ligand that recruits and activates tyrosine kinases required for pedestal formation
-
Bommarius B., et al. Enteropathogenic Escherichia coli Tir is an SH2/3 ligand that recruits and activates tyrosine kinases required for pedestal formation. Mol. Microbiol. 63 (2007) 1748-1768
-
(2007)
Mol. Microbiol.
, vol.63
, pp. 1748-1768
-
-
Bommarius, B.1
-
49
-
-
34248645155
-
Entry of the bacterial pathogen Listeria monocytogenes into mammalian cells
-
Ireton K. Entry of the bacterial pathogen Listeria monocytogenes into mammalian cells. Cell Microbiol. 9 (2007) 1365-1375
-
(2007)
Cell Microbiol.
, vol.9
, pp. 1365-1375
-
-
Ireton, K.1
-
50
-
-
1542373523
-
Protein phosphorylation on tyrosine in bacteria
-
Cozzone A.J., et al. Protein phosphorylation on tyrosine in bacteria. Arch. Microbiol. 181 (2004) 171-181
-
(2004)
Arch. Microbiol.
, vol.181
, pp. 171-181
-
-
Cozzone, A.J.1
-
51
-
-
0036295212
-
Classification and evolution of P-loop GTPases and related ATPases
-
Leipe D.D., et al. Classification and evolution of P-loop GTPases and related ATPases. J. Mol. Biol. 317 (2002) 41-72
-
(2002)
J. Mol. Biol.
, vol.317
, pp. 41-72
-
-
Leipe, D.D.1
-
52
-
-
33645967147
-
Role of MinD-membrane association in Min protein interactions
-
Taghbalout A., et al. Role of MinD-membrane association in Min protein interactions. J. Bacteriol. 188 (2006) 2993-3001
-
(2006)
J. Bacteriol.
, vol.188
, pp. 2993-3001
-
-
Taghbalout, A.1
-
53
-
-
0036510550
-
Tyrosine phosphorylation of protein kinase Wzc from Escherichia coli K12 occurs through a two-step process
-
Grangeasse C., et al. Tyrosine phosphorylation of protein kinase Wzc from Escherichia coli K12 occurs through a two-step process. J. Biol. Chem. 277 (2002) 7127-7135
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 7127-7135
-
-
Grangeasse, C.1
-
54
-
-
0033539643
-
A novel bacterial tyrosine kinase essential for cell division and differentiation
-
Wu J., et al. A novel bacterial tyrosine kinase essential for cell division and differentiation. Proc. Natl. Acad. Sci. U. S. A. 96 (1999) 13068-13073
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 13068-13073
-
-
Wu, J.1
-
55
-
-
27144440950
-
A tyrosine kinase and its activator control the activity of the CtsR heat shock repressor in B. subtilis
-
Kirstein J., et al. A tyrosine kinase and its activator control the activity of the CtsR heat shock repressor in B. subtilis. EMBO J. 24 (2005) 3435-3445
-
(2005)
EMBO J.
, vol.24
, pp. 3435-3445
-
-
Kirstein, J.1
-
56
-
-
33751272653
-
Structural biology of protein tyrosine kinases
-
Cowan-Jacob S.W. Structural biology of protein tyrosine kinases. Cell. Mol. Life Sci. 63 (2006) 2608-2625
-
(2006)
Cell. Mol. Life Sci.
, vol.63
, pp. 2608-2625
-
-
Cowan-Jacob, S.W.1
-
57
-
-
67649948824
-
Emerging structural insights into bacterial tyrosine kinases
-
Lee D.C., and Jia Z. Emerging structural insights into bacterial tyrosine kinases. Trends Biochem. Sci. 34 (2009) 351-357
-
(2009)
Trends Biochem. Sci.
, vol.34
, pp. 351-357
-
-
Lee, D.C.1
Jia, Z.2
-
58
-
-
34548168616
-
New peptide nucleic acid analogues: synthesis and applications
-
Pensato S., et al. New peptide nucleic acid analogues: synthesis and applications. Expert Opin. Biol. Ther. 7 (2007) 1219-1232
-
(2007)
Expert Opin. Biol. Ther.
, vol.7
, pp. 1219-1232
-
-
Pensato, S.1
-
59
-
-
70449708559
-
Inhibitors of protein kinases and uses thereof. International patent
-
Ottawa, Ontario, Canada
-
Terreux, R. and Phipps, J. (2006) Inhibitors of protein kinases and uses thereof. International patent no. WO/2006/108270, Pharmagap Inc., Ottawa, Ontario, Canada
-
(2006)
WO/2006/108270, Pharmagap Inc
-
-
Terreux, R.1
Phipps, J.2
-
60
-
-
0029020282
-
The eukaryotic protein kinase (catalytic) domain structure and classification
-
Hanks S.K., and Hunter T. The eukaryotic protein kinase (catalytic) domain structure and classification. FASEB J. 9 (1995) 576-596
-
(1995)
FASEB J.
, vol.9
, pp. 576-596
-
-
Hanks, S.K.1
Hunter, T.2
-
61
-
-
0037337317
-
Structure of Mycobacterium tuberculosis PknB supports a universal activation mechanism for Ser/Thr protein kinases
-
Young T.A., et al. Structure of Mycobacterium tuberculosis PknB supports a universal activation mechanism for Ser/Thr protein kinases. Nat. Struct. Biol. 10 (2003) 168-174
-
(2003)
Nat. Struct. Biol.
, vol.10
, pp. 168-174
-
-
Young, T.A.1
-
62
-
-
2342578723
-
Sensor domain of the Mycobacterium tuberculosis receptor Ser/Thr protein kinase, PknD, forms a highly symmetric beta propeller
-
Good M.C., et al. Sensor domain of the Mycobacterium tuberculosis receptor Ser/Thr protein kinase, PknD, forms a highly symmetric beta propeller. J. Mol. Biol. 339 (2004) 459-469
-
(2004)
J. Mol. Biol.
, vol.339
, pp. 459-469
-
-
Good, M.C.1
-
63
-
-
34547537909
-
Structural basis for the specific inhibition of protein kinase G, a virulence factor of Mycobacterium tuberculosis
-
Scherr N., et al. Structural basis for the specific inhibition of protein kinase G, a virulence factor of Mycobacterium tuberculosis. Proc. Natl. Acad. Sci. U. S. A. 104 (2007) 12151-12156
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 12151-12156
-
-
Scherr, N.1
-
64
-
-
0036711089
-
The PASTA domain: a beta-lactam-binding domain
-
Yeats C., et al. The PASTA domain: a beta-lactam-binding domain. Trends Biochem. Sci. 27 (2002) 438-440
-
(2002)
Trends Biochem. Sci.
, vol.27
, pp. 438-440
-
-
Yeats, C.1
-
65
-
-
54549099189
-
A eukaryotic-like Ser/Thr kinase signals bacteria to exit dormancy in response to peptidoglycan fragments
-
Shah I.M., et al. A eukaryotic-like Ser/Thr kinase signals bacteria to exit dormancy in response to peptidoglycan fragments. Cell 135 (2008) 486-496
-
(2008)
Cell
, vol.135
, pp. 486-496
-
-
Shah, I.M.1
-
66
-
-
40549131346
-
Current understanding on biosynthesis of microbial polysaccharides
-
Guo H., et al. Current understanding on biosynthesis of microbial polysaccharides. Curr. Top. Med. Chem. 8 (2008) 141-151
-
(2008)
Curr. Top. Med. Chem.
, vol.8
, pp. 141-151
-
-
Guo, H.1
-
67
-
-
63849263023
-
Pivotal role of the outer membrane polysaccharide export and polysaccharide copolymerase protein families in export of extracellular polysaccharides in gram-negative bacteria
-
Cuthbertson L., et al. Pivotal role of the outer membrane polysaccharide export and polysaccharide copolymerase protein families in export of extracellular polysaccharides in gram-negative bacteria. Microbiol. Mol. Biol. Rev. 73 (2009) 155-177
-
(2009)
Microbiol. Mol. Biol. Rev.
, vol.73
, pp. 155-177
-
-
Cuthbertson, L.1
-
68
-
-
0037310572
-
Involvement of a protein tyrosine kinase in production of the polymeric bioemulsifier emulsan from the oil-degrading strain Acinetobacter lwoffii RAG-1
-
Nakar D., and Gutnick D.L. Involvement of a protein tyrosine kinase in production of the polymeric bioemulsifier emulsan from the oil-degrading strain Acinetobacter lwoffii RAG-1. J. Bacteriol. 185 (2003) 1001-1009
-
(2003)
J. Bacteriol.
, vol.185
, pp. 1001-1009
-
-
Nakar, D.1
Gutnick, D.L.2
-
69
-
-
0030430612
-
Protein-tyrosine phosphatase activity of Coxiella burnetii that inhibits human neutrophils
-
Li Y.P., et al. Protein-tyrosine phosphatase activity of Coxiella burnetii that inhibits human neutrophils. Acta Virol. 40 (1996) 263-272
-
(1996)
Acta Virol.
, vol.40
, pp. 263-272
-
-
Li, Y.P.1
-
70
-
-
0031013793
-
Characterization of the amsI product as a low molecular weight acid phosphatase controlling exopolysaccharide synthesis of Erwinia amylovora
-
Bugert P., and Geider K. Characterization of the amsI product as a low molecular weight acid phosphatase controlling exopolysaccharide synthesis of Erwinia amylovora. FEBS Lett. 400 (1997) 252-256
-
(1997)
FEBS Lett.
, vol.400
, pp. 252-256
-
-
Bugert, P.1
Geider, K.2
-
71
-
-
0033564208
-
Protein tyrosine kinases in bacterial pathogens are associated with virulence and production of exopolysaccharide
-
Ilan O., et al. Protein tyrosine kinases in bacterial pathogens are associated with virulence and production of exopolysaccharide. EMBO J. 18 (1999) 3241-3248
-
(1999)
EMBO J.
, vol.18
, pp. 3241-3248
-
-
Ilan, O.1
-
72
-
-
0033038516
-
Cells of Escherichia coli contain a protein-tyrosine kinase, Wzc, and a phosphotyrosine-protein phosphatase, Wzb
-
Vincent C., et al. Cells of Escherichia coli contain a protein-tyrosine kinase, Wzc, and a phosphotyrosine-protein phosphatase, Wzb. J. Bacteriol. 181 (1999) 3472-3477
-
(1999)
J. Bacteriol.
, vol.181
, pp. 3472-3477
-
-
Vincent, C.1
-
73
-
-
0038011029
-
Co-ordination of pathogenicity island expression by the BipA GTPase in enteropathogenic Escherichia coli (EPEC)
-
Grant A.J., et al. Co-ordination of pathogenicity island expression by the BipA GTPase in enteropathogenic Escherichia coli (EPEC). Mol. Microbiol. 48 (2003) 507-521
-
(2003)
Mol. Microbiol.
, vol.48
, pp. 507-521
-
-
Grant, A.J.1
-
74
-
-
5644225534
-
The Helicobacter pylori CagA protein induces protein dephosphorylation of ezrin
-
Selbach M., et al. The Helicobacter pylori CagA protein induces protein dephosphorylation of ezrin. Proteomics 4 (2004) 2961-2968
-
(2004)
Proteomics
, vol.4
, pp. 2961-2968
-
-
Selbach, M.1
-
75
-
-
0036141034
-
Isolation and characterization of a protein-tyrosine kinase and a phosphotyrosine-protein phosphatase from Klebsiella pneumoniae
-
Preneta R., et al. Isolation and characterization of a protein-tyrosine kinase and a phosphotyrosine-protein phosphatase from Klebsiella pneumoniae. Comp. Biochem. Physiol. B 131 (2002) 103-112
-
(2002)
Comp. Biochem. Physiol. B
, vol.131
, pp. 103-112
-
-
Preneta, R.1
-
76
-
-
17144424245
-
Translation elongation factor EF-Tu is a target for Stp, a serine-threonine phosphatase involved in virulence of Listeria monocytogenes
-
Archambaud C., et al. Translation elongation factor EF-Tu is a target for Stp, a serine-threonine phosphatase involved in virulence of Listeria monocytogenes. Mol. Microbiol. 56 (2005) 383-396
-
(2005)
Mol. Microbiol.
, vol.56
, pp. 383-396
-
-
Archambaud, C.1
-
77
-
-
66549090908
-
Mycobacterium tuberculosis PtkA is a novel tyrosine kinase whose substrate is PtpA
-
Bach H., et al. Mycobacterium tuberculosis PtkA is a novel tyrosine kinase whose substrate is PtpA. Biochem. J. 420 (2009) 155-160
-
(2009)
Biochem. J.
, vol.420
, pp. 155-160
-
-
Bach, H.1
-
78
-
-
0033806882
-
Cloning and characterization of secretory tyrosine phosphatases of Mycobacterium tuberculosis
-
Koul A., et al. Cloning and characterization of secretory tyrosine phosphatases of Mycobacterium tuberculosis. J. Bacteriol. 182 (2000) 5425-5432
-
(2000)
J. Bacteriol.
, vol.182
, pp. 5425-5432
-
-
Koul, A.1
-
79
-
-
0141454865
-
PknB kinase is regulated by phosphorylation in two Thr residues and dephosphorylation by PstP, the cognate phopho-Ser/Thr phosphatase, in Mycobacterium tuberculosis
-
Boitel B., et al. PknB kinase is regulated by phosphorylation in two Thr residues and dephosphorylation by PstP, the cognate phopho-Ser/Thr phosphatase, in Mycobacterium tuberculosis. Mol. Microbiol. 49 (2003) 1493-1508
-
(2003)
Mol. Microbiol.
, vol.49
, pp. 1493-1508
-
-
Boitel, B.1
-
80
-
-
0037085431
-
WaaP of Pseudomonas aeruginosa is a novel eukaryotic type protein-tyrosine kinase as well as a sugar kinase essential for the biosynthesis of core lipopolysaccharide
-
Zhao X., and Lam J.S. WaaP of Pseudomonas aeruginosa is a novel eukaryotic type protein-tyrosine kinase as well as a sugar kinase essential for the biosynthesis of core lipopolysaccharide. J. Biol. Chem. 277 (2002) 4722-4730
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 4722-4730
-
-
Zhao, X.1
Lam, J.S.2
-
81
-
-
0032431404
-
A novel serine/threonine protein kinase homologue of Pseudomonas aeruginosa is specifically inducible within the host infection site and is required for full virulence in neutropenic mice
-
Wang J., et al. A novel serine/threonine protein kinase homologue of Pseudomonas aeruginosa is specifically inducible within the host infection site and is required for full virulence in neutropenic mice. J. Bacteriol. 180 (1998) 6764-6768
-
(1998)
J. Bacteriol.
, vol.180
, pp. 6764-6768
-
-
Wang, J.1
-
82
-
-
0032701102
-
Characterization of a Hank's type serine/threonine phosphoprotein phosphatase in Pseudomonas aeruginosa
-
Mukhopadhyay S., et al. Characterization of a Hank's type serine/threonine phosphoprotein phosphatase in Pseudomonas aeruginosa. J. Bacteriol. 181 (1999) 6615-6622
-
(1999)
J. Bacteriol.
, vol.181
, pp. 6615-6622
-
-
Mukhopadhyay, S.1
-
83
-
-
0029135229
-
Molecular characterization of the eps gene cluster of Pseudomonas solanacearum and its transcriptional regulation at a single promoter
-
Huang J., and Schell M. Molecular characterization of the eps gene cluster of Pseudomonas solanacearum and its transcriptional regulation at a single promoter. Mol. Microbiol. 16 (1995) 977-989
-
(1995)
Mol. Microbiol.
, vol.16
, pp. 977-989
-
-
Huang, J.1
Schell, M.2
-
84
-
-
0031053944
-
Molecular characterization of the Salmonella typhi StpA protein that is related to both Yersinia YopE cytotoxin and YopH tyrosine phosphatase
-
Arricau N., et al. Molecular characterization of the Salmonella typhi StpA protein that is related to both Yersinia YopE cytotoxin and YopH tyrosine phosphatase. Res. Microbiol. 148 (1997) 21-26
-
(1997)
Res. Microbiol.
, vol.148
, pp. 21-26
-
-
Arricau, N.1
-
85
-
-
41049112960
-
The prpZ gene cluster encoding eukaryotic-type Ser/Thr protein kinases and phosphatases is repressed by oxidative stress and involved in Salmonella enterica serovar Typhi survival in human macrophages
-
Faucher S.P., et al. The prpZ gene cluster encoding eukaryotic-type Ser/Thr protein kinases and phosphatases is repressed by oxidative stress and involved in Salmonella enterica serovar Typhi survival in human macrophages. FEMS Microbiol. Lett. 281 (2008) 160-166
-
(2008)
FEMS Microbiol. Lett.
, vol.281
, pp. 160-166
-
-
Faucher, S.P.1
-
86
-
-
0035214193
-
Role of tyrosine kinases and the tyrosine phosphatase SptP in the interaction of Salmonella with host cells
-
Murli S., et al. Role of tyrosine kinases and the tyrosine phosphatase SptP in the interaction of Salmonella with host cells. Cell. Microbiol. 3 (2001) 795-810
-
(2001)
Cell. Microbiol.
, vol.3
, pp. 795-810
-
-
Murli, S.1
-
87
-
-
0034891240
-
The molecular weight distribution of succinoglycan produced by Sinorhizobium meliloti is influenced by specific tyrosine phosphorylation and ATPase activity of the cytoplasmic domain of the ExoP protein
-
Niemeyer D., and Becker A. The molecular weight distribution of succinoglycan produced by Sinorhizobium meliloti is influenced by specific tyrosine phosphorylation and ATPase activity of the cytoplasmic domain of the ExoP protein. J. Bacteriol. 185 (2001) 5163-5170
-
(2001)
J. Bacteriol.
, vol.185
, pp. 5163-5170
-
-
Niemeyer, D.1
Becker, A.2
-
88
-
-
0030738041
-
The Staphylococcus aureus allelic genetic loci for serotype 5 and 8 capsule expression contain the type-specific genes flanked by common genes
-
Sau S., et al. The Staphylococcus aureus allelic genetic loci for serotype 5 and 8 capsule expression contain the type-specific genes flanked by common genes. Microbiology 143 (1997) 2395-2405
-
(1997)
Microbiology
, vol.143
, pp. 2395-2405
-
-
Sau, S.1
-
89
-
-
0036723797
-
Staphylococcus aureus contains two low-molecular-mass phosphotyrosine-protein phosphatases
-
Soulat D., et al. Staphylococcus aureus contains two low-molecular-mass phosphotyrosine-protein phosphatases. J. Bacteriol. 184 (2002) 5194-5199
-
(2002)
J. Bacteriol.
, vol.184
, pp. 5194-5199
-
-
Soulat, D.1
-
90
-
-
0035808397
-
Functional analysis in type Ia group B Streptococcus of a cluster of genes involved in extracellular polysaccharide production by diverse species of Streptococci
-
Cieslewicz M.J., et al. Functional analysis in type Ia group B Streptococcus of a cluster of genes involved in extracellular polysaccharide production by diverse species of Streptococci. J. Biol. Chem. 276 (2001) 139-146
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 139-146
-
-
Cieslewicz, M.J.1
-
91
-
-
0037853258
-
A eukaryotic type serine/threonine kinase and phosphatase in Streptococcus agalactiae reversibly phosphorylate an inorganic pyrophosphatase and affect growth, cell segregation, and virulence
-
Rajagopal L., et al. A eukaryotic type serine/threonine kinase and phosphatase in Streptococcus agalactiae reversibly phosphorylate an inorganic pyrophosphatase and affect growth, cell segregation, and virulence. J. Biol. Chem. 278 (2003) 14429-14441
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 14429-14441
-
-
Rajagopal, L.1
-
92
-
-
0141891397
-
Positive correlation between tyrosine phosphorylation of CpsD and capsular polysaccharide production in Streptococcus pneumoniae
-
Bender M.H., et al. Positive correlation between tyrosine phosphorylation of CpsD and capsular polysaccharide production in Streptococcus pneumoniae. J. Bacteriol. 185 (2003) 6057-6066
-
(2003)
J. Bacteriol.
, vol.185
, pp. 6057-6066
-
-
Bender, M.H.1
-
93
-
-
33645054791
-
Identification and biochemical characterization of a eukaryotic-type serine/threonine kinase and its cognate phosphatase in Streptococcus pyogenes
-
Jin H., and Pancholi V. Identification and biochemical characterization of a eukaryotic-type serine/threonine kinase and its cognate phosphatase in Streptococcus pyogenes. J. Mol. Biol. 357 (2006) 1351-1372
-
(2006)
J. Mol. Biol.
, vol.357
, pp. 1351-1372
-
-
Jin, H.1
Pancholi, V.2
-
94
-
-
34047274962
-
Yersinia protein kinase YopO is activated by a novel G-actin binding process
-
Trasak C., et al. Yersinia protein kinase YopO is activated by a novel G-actin binding process. J. Biol. Chem. 282 (2007) 2268-2277
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 2268-2277
-
-
Trasak, C.1
-
95
-
-
0034192286
-
Yop effectors of Yersinia spp. and actin rearrangements
-
Bliska J.B. Yop effectors of Yersinia spp. and actin rearrangements. Trends Microbiol. 8 (2000) 205-208
-
(2000)
Trends Microbiol.
, vol.8
, pp. 205-208
-
-
Bliska, J.B.1
-
96
-
-
33747780120
-
The Ser/Thr kinase activity of the Yersinia protein kinase A (YpkA) is necessary for full virulence in the mouse, mollifying phagocytes, and disrupting the eukaryotic cytoskeleton
-
Wiley D.J., et al. The Ser/Thr kinase activity of the Yersinia protein kinase A (YpkA) is necessary for full virulence in the mouse, mollifying phagocytes, and disrupting the eukaryotic cytoskeleton. Microb. Pathog. 40 (2006) 234-243
-
(2006)
Microb. Pathog.
, vol.40
, pp. 234-243
-
-
Wiley, D.J.1
|