Oxidized low density lipoprotein decreases Rankl-induced differentiation of osteoclasts by inhibition of Rankl signaling

Journal of Cellular Physiology

Volumn 221, Issue 3, 2009, Pages 572-578

  Mazière, Cécile ^a,b,c   Louvet, Loïc ^a   Gomila, Cathy ^b   Kamel, Said ^a,c   Massy, Ziad ^a,c   Mazière, Jean Claude ^a,b,c  

^a INSERM   (France)

^b Northern Hospital   (France)

^c UNIVERSITÉ DE PICARDIE JULES VERNE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; BUTHIONINE SULFOXIMINE; DNA; GLUTATHIONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; OSTEOCLAST DIFFERENTIATION FACTOR; OXIDIZED LOW DENSITY LIPOPROTEIN; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR NFAT3; ACID PHOSPHATASE; ISOENZYME; LOW DENSITY LIPOPROTEIN; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; TARTRATE-RESISTANT ACID PHOSPHATASE; TNFSF11 PROTEIN, HUMAN; TNFSF11 PROTEIN, MOUSE; TRANSCRIPTION FACTOR NFAT;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; ATHEROSCLEROSIS; BLOOD SAMPLING; BLOOD VESSEL CALCIFICATION; BONE REMODELING; CELL DIFFERENTIATION; DNA BINDING; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; MACROPHAGE; MONOCYTE; MOUSE; NONHUMAN; OSTEOCLAST; OSTEOLYSIS; OXIDATIVE STRESS; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; ANIMAL; CYTOLOGY; DRUG EFFECT; HUMAN; METABOLISM; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY; TUMOR CELL LINE;

ACID PHOSPHATASE; ANIMALS; BONE RESORPTION; BUTHIONINE SULFOXIMINE; CELL DIFFERENTIATION; CELL LINE, TUMOR; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GLUTATHIONE; HUMANS; ISOENZYMES; LIPOPROTEINS, LDL; MACROPHAGES; MAP KINASE KINASE 4; MICE; MONOCYTES; NF-KAPPA B; NFATC TRANSCRIPTION FACTORS; OSTEOCLASTS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; RANK LIGAND; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 70449718871     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.21886     Document Type: Article

References (42)

1. Aitken CJ, Hodge JM, Nishinaka Y, Vaughan T, Yodoi J, Day CJ, Morrison NA, Nicholson GC. 2004. Regulation of human osteoclast differentiation by thioredoxin binding protein-2 and redox-sensitive signaling. J Bone Miner Res 19:2057-2064. (Pubitemid 41103421)
2. Anderson DM, Maraskovsky E, Billingsley WL, Dougall WC, Tometslo ME, Roux ER, Tepee MC, DuBose RF, Cosman D, Galibert L, Asagiri M, Sato K, Usami T, Ochi S, Nishina H, Yoshida H, Morita I, Wagner EF, Mak TW, Sertling E, Takayanagi H. 1997. A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function. Nature 390:175-179. (Pubitemid 27507987)
3. Anusaksathien O, Laplace C, li X, Ren Y, Peng L, Goldring SR, Galson DL. 2001. Tissue-specific and ubiquitous promoters direct the expression of alternatively spliced transcripts from the calcitonin receptor gene. J Biol Chem 276:22663-22674.
4. Anwar AA, Li FY, Leake DS, Ishii T, Mann GE, Siow RC. 2005. Induction of heme oxygenase 1 by moderately oxidized low-density lipoproteins in human vascular smooth muscle cells: Role of mitogen-activated protein kinases and Nrf2. Free Rad Biol Med 39:227-236. (Pubitemid 40814548)
5. Asagiri M, Takayanagi H. 2007. The molecular understanding of osteoclast differentiation. Bone 40:251-264.
6. Asagiri M, Sato K, Usami T, Ochi S, Nishina H, Yoshida H, Morita I, Wagner EF, Mak TW, Serfling E, Takayanagi H. 2005. Autoamplification of NFATc1 expression determines its essential role in bone homeostasis. J Exp Med 202:1261-1269. (Pubitemid 41586956)
7. Augé N, Escargueil-blanc I, Lajoie-Mazenc I, Suc I, Andrieu-Abadie N, Pieraggi MT, Chatelut M, Thiers JC, Jaffrezou JP, Laurent G, Levade T, Nègre-salvayre A, Salvayre R. 1998. Potential role for ceramide inmitogen-activated protein kinase activation and proliferation of vascular smooth muscle cells induced by oxidized low density lipoprotein. J Biol Chem 273:12893-12900. (Pubitemid 28246848)
8. Bas A, Lopez I, Perez J, Rodriguez M, Aguilera-Tejero E. 2006. Reversibility of calcitriol-induced medial artery calcification in rats with intact renal function. J Bone Miner Res 21:484-490. (Pubitemid 43306570)
9. Breitkreutz I, Raab MS, Vallet S, Hideshima T, Raje N, Chauhan D, Minshi NC, Richardson PG, Anderson KC. 2007. Targeting MEK1/2 blocks osteoclast differentiation, function and cytokine secretion in multiple myeloma. Br J Haematol 139:55-63. (Pubitemid 47389922)
10. Darnay BG, Haridas V, Ni J, Moore PA, Aggarwal BB. 1998. Characterization of the intracellular domain of receptor activator of NF-kappaB (RANK). Interaction with tumor necrosis factor receptor associated factors and activation of NF-kappaB and c-Jun N-terminal kinase. J Biol Chem 273:20551-20555. (Pubitemid 28377625)
11. Fraser JH, Helfrich MH, Wallace HM, Ralston SH. 1996. Hydrogen peroxide, but not superoxide, stimulates bone resorption in mouse calvariae. Bone 19:223-226.
12. Ginery A, Bradley E, Shaw A, Oursler MJ. 2003. Phosphatidylinositol 3-kinase coordinately activates the MEK/ERK and AKT/NFkappaB pathways to maintain osteoclast survival. J Cell Biochem 89:165-179. (Pubitemid 36459107)
13. Havel RJ, Eden MA, Bragdon JH. 1955. The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum. J Clin Invest 34:1345-1353.
14. Huh YJ, Kim JM, Kim H, Song H, So H, Lee SY, Kwon SB, Kim HH, Lee SH, Choi Y, Chung SC, Jeong DW, Min BM. 2006. Regulation of osteoclast differentiation by the redox-dependent modulation of nuclear import of transcription factors. Cell Death Differ 13:1138-1146. (Pubitemid 43905595)
15. Ikeda F, Nishimura R, Matsubara T, Tanaka S, Inoue J, Reddy SV, Hata K, Yamashita K, Hiraga T, Watanabe T, Kukita T, Yoshioka K, Rao A, Yoneda T. 2004. Critical role of c-Jun signaling in regulation of NFAT family and RANKL-regulated osteoclast differentiation. J Clin Invest 114: 475-484. (Pubitemid 39572097)
16. Ikeda F, Nishimura R, Matsubara T, Hata K, Reddy SV, Yoneda T. 2006. Activation of NFAT signal in vivo leads to osteopenia associated with increased osteoclastogenesis and bone-resorbing activity. J Immunol 177:2384-2390. (Pubitemid 44200999)
17. Jeziorska M, McCollum C, Wooley DE. 1998. Observations on bone formation and remodelling in advanced atherosclerotic lesions of human carotid arteries. Virchows Arch 433:559-565. (Pubitemid 28561189)
18. Kim Y, Sato K, Asagiri M, Morita I, Soma K, Takayanagi H. 2005. Contribution of nuclear factor of activated T cells c1 to the transcriptional control of immunoreceptor osteoclast-associated receptor but not triggering receptor expressed by myeloid cells-2 during osteoclastogenesis. J Biol Chem 280:32905-32913. (Pubitemid 41368340)
19. Lacey DL, Timms E, Tan HL, Kelley MJ, Dunstan CR, Burgess T, Elliott R, Colombero A, Elliott G, Scully S, Hsu H, Sullivan J, Hawkins N, Davy E, Capparelli C, Eli A, Qian YX, Kaufman S, Sarosi I, Shalhoub V, Senaldi G, Guo J, Delaney J, Boyle WJ. 1998. Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation. Cell 93:165-176.
20. Lee FY, Kim DW, Karmin JA, Hong D, Chang SS, Fugisawa M, Takayanagi H, Bigliani LU, Blaine TA, Lee HJ. 2005. Mu-Calpain regulates receptor activator of NF-kappaB ligand (RANKL)- supported osteoclastogenesis via NF-kappaB activation in RAW 264.7 cells. J Biol Chem 280:29929-29936.
21. Li D, Yang B, Mehta JL. 1998. Ox-LDL induces apoptosis in human coronary artery endothelial cells: Role of PKC, PTK, bcl-2, and Fas. Am J Physiol 275:H568-H576.
22. Li HL, Wang AB, Zhang R, Wei YS, Chen HZ, She ZG, Huang Y, Liu DP, Liang CC. 2006. A20 inhibits oxidized low-density lipoprotein-induced apoptosis through negative Fas/Fas ligand-dependent activation of caspase-8 and mitochondrial pathways in murine RAW264.7 macrophages. J Cell Physiol 208:307-318.
23. Luegmayr E, Glantschnig H, Wesolowski GA, Gentile MA, Fisher JE, Rodan GA, Reszka AA. 2004. Osteoclast formation, survival and morphology are highly dependent on exogenous cholesterol/lipoproteins. Cell Death Differ 11:S108-S118.
24. Matsumoto M, Sudo T, Saito T, Osada H, Tsujimoto M. 2000. Involvement of p38 mitogen-activated protein kinase signaling pathway in osteoclastogenesis mediated by receptor activator of NF-kappa B ligand (RANKL). J Biol Chem 275:31155-31161.
25. Matsuo K, Galson DL, Zhao C, Peng L, Laplace C, Wang KZ, Bachler MA, Amano H, Aburatani H, Ishikawa H, Wagner EF. 2004. Nuclear factor of activated T-cells (NFAT) rescues osteoclastogenesis in precursors lacking c-Fos. J Biol Chem 279:26475-26480. (Pubitemid 38798801)
26. Mazière C, Auclair M, Djavaheri-Mergny M, Packer L, Mazière JC. 1996. Oxidized low density lipoprotein induces activation of the transcription factor NF kappa B in fibroblasts, endothelial and smooth muscle cells. Biochem Mol Biol Int 39:1201-1207.
27. Mazière C, Djavaheri-Mergny M, Frey-Fressart V, Delattre J, Mazière JC. 1997. Copper and cell oxidized low-density lipoprotein induces activator protein 1 in fibroblasts, endothelial and smooth muscle cells. FEBS Lett 409:351-356.
28. Mazière C, Alimardani G, Dantin F, Dubois F, Conte MA, Mazière JC. 1999. Oxidized LDL activates STAT1 and STAT3 transcription factors: Possible involvement of reactive oxygen species. FEBS Lett 448:49-52.
29. Mazière C, Meignotte A, Dantin F, Conte MA, Mazière JC. 2000. Oxidized LDL induces an oxidative stress and activates the tumor suppressor p53 in MRC5 human fibroblasts. Biochem Biophys Res Commun 276:718-723.
30. Mazière C, Floret S, Santus R, Morlière P, Marcheux V, Mazière JC. 2003 Impairment of the EGF signaling pathway by the oxidative stress generated with UVA. Free Radic Biol Med 34:629-636.
31. Mazière C, Morlière P, Santus R, Marcheux V, Louandre C, Conte MA, Mazière JC. 2004. Inhibition of insulin signaling by oxidized low density lipoprotein. Protective effect of the antioxidant Vitamin E. Atherosclerosis 175:23-30.
32. Mazière C, Morlière P, Massy Z, Kamel S, Louandre C, Conte MA, Mazière JC. 2005. Oxidized low-density lipoprotein elicits an intracellular calcium rise and increases the binding activity of the transcription factor NFAT. Free Radic Biol Med 38:472-480.
33. Morel DW, Hessler JR, Chisolm GM. 1983. Low density lipoprotein cytotoxicity induced by free radical peroxidation of lipid. J Lipid Res 24:1070-1076.
34. Ninomiya-Tsuji J, Kishimoto K, Hiyama A, Inoue J, Cao Z, Matsumoto K. 1999. The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway. Nature 398:252-256. (Pubitemid 29142861)
35. Scott JA, Homcy CJ, Khaw BA, Rabito CA. 1988. Quantitation of intracellular oxidation in a renal epithelial cell line. Free Rad Biol Med 4:79-83.
36. Senokuchi T, Matsumura T, Sakai M, Matsuo T, Yano M, Kiritoshi S, Sonoda K, Kukidome D, Nishikawa T, Araki E. 2004. Extracellular signal-regulated kinase and p38 mitogen-activated protein kinase mediate macrophage proliferation induced by oxidized low-density lipoprotein. Atherosclerosis 176:233-245. (Pubitemid 39369512)
37. Steinberg D. 2005. Hypercholesterolemia and inflammation in atherogenesis: Two sides of the same coin. Mol Nutr Food Res 49:995-998. (Pubitemid 41735560)
38. Steitz SA, Speer MY, Curinga G, Yang HY, haynes P, Aebersold R, Schinke T, Karsenty G, Giachelli CM. 2001. Smooth muscle cell phenotypic transition associatedwith calcification: Upregulation of Cbfa1 and downregulation of smooth muscle lineage markers. Circ Res 89:1147-1154.
39. Takayanagi H, Kim S, Koga T, Nishina H, Isshiki M, Yoshida H, Saiura A, Isobe M, Yokochi T, Inoue J, Wagner EF, Mak TW, Kodoma T, Taniguchi T. 2002. Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts. Dev Cell 3:889-901. (Pubitemid 35460788)
40. Theill LE, Boyle WJ, Penninger JM. 2002. RANK-L and RANK: T cells, bone loss, and mammalian evolution. Annu Rev Immunol 20:795-823.
41. Yagi K. 1987. Lipid peroxide and human diseases. Chem Phys Lipids 45:337-351.
42. Yip KH, Zheng MH, Steer JH, Giardina TM, Han R, Lo SZ, Bakker AJ, Cassady AI, Joyce DA, Xu J. 2005. Thapsigargin modulates osteoclastogenesis through the regulation of RANKL-induced Signalling pathways and reactive oxygen species production. J Bone Miner Res 20:1462-1471. (Pubitemid 41033530)