메뉴 건너뛰기




Volumn 390, Issue 3, 2009, Pages 570-576

Molecular differentiation in epiphyseal and physeal cartilage. Prominent role for gremlin in maintaining hypertrophic chondrocytes in epiphyseal cartilage

Author keywords

Chondrocyte; Epiphysis; Gremlin; Hypertrophic chondrocyte; Laser capture microdissection; Microarray; Physis

Indexed keywords

EPIDERMAL GROWTH FACTOR CONTAINING FIBULIN LIKE EXTRACELLULAR MATRIX PROTEIN 1; FRIZZLED RELATED PROTEIN; GLYCOPROTEIN; GREMLIN; HEDGEHOG INTERACTING PROTEIN; PROLINE ARGININE RICH END LEUCINE RICH REPEAT PROTEIN; PYROPHOSPHATASE 1; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

EID: 70449699602     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.10.006     Document Type: Article
Times cited : (8)

References (36)
  • 1
    • 0038687536 scopus 로고    scopus 로고
    • Developmental regulation of the growth plate
    • Kronenberg H.M. Developmental regulation of the growth plate. Nature 423 (2003) 332-336
    • (2003) Nature , vol.423 , pp. 332-336
    • Kronenberg, H.M.1
  • 3
    • 0028067659 scopus 로고
    • Mechanism of longitudinal bone growth and its regulation by growth plate chondrocytes
    • Hunziker E.B. Mechanism of longitudinal bone growth and its regulation by growth plate chondrocytes. Microsc. Res. Technol. 28 (1994) 505-519
    • (1994) Microsc. Res. Technol. , vol.28 , pp. 505-519
    • Hunziker, E.B.1
  • 4
    • 0036046058 scopus 로고    scopus 로고
    • Structural stages in the development of the long bones and epiphyses. A study in the New Zealand white rabbit
    • Rivas R., and Shapiro F. Structural stages in the development of the long bones and epiphyses. A study in the New Zealand white rabbit. J. Bone Joint Surg. Am. 84 (2002) 85-100
    • (2002) J. Bone Joint Surg. Am. , vol.84 , pp. 85-100
    • Rivas, R.1    Shapiro, F.2
  • 5
    • 0033402727 scopus 로고    scopus 로고
    • The BMP antagonist gremlin regulates outgrowth, chondrogenesis and programmed cell death in the developing limb
    • Merino R., Rodriguez-Leon J., Macias D., Ganan Y., Economides A.N., and Hurle J.M. The BMP antagonist gremlin regulates outgrowth, chondrogenesis and programmed cell death in the developing limb. Development 126 (1999) 5515-5522
    • (1999) Development , vol.126 , pp. 5515-5522
    • Merino, R.1    Rodriguez-Leon, J.2    Macias, D.3    Ganan, Y.4    Economides, A.N.5    Hurle, J.M.6
  • 6
    • 0041030051 scopus 로고    scopus 로고
    • Signal relay by BMP antagonism controls the SHH/FGF4 feedback loop in vertebrate limb buds
    • Zuniga A., Haramis A.P., McMahon A.P., and Zeller R. Signal relay by BMP antagonism controls the SHH/FGF4 feedback loop in vertebrate limb buds. Nature 401 (1999) 598-602
    • (1999) Nature , vol.401 , pp. 598-602
    • Zuniga, A.1    Haramis, A.P.2    McMahon, A.P.3    Zeller, R.4
  • 7
    • 0037743636 scopus 로고    scopus 로고
    • Gremlin is the BMP antagonist required for maintenance of Shh and Fgf signals during limb patterning
    • Khokha M.K., Hsu D., Brunet L.J., Dionne M.S., and Harland R.M. Gremlin is the BMP antagonist required for maintenance of Shh and Fgf signals during limb patterning. Nat. Genet. 34 (2003) 303-307
    • (2003) Nat. Genet. , vol.34 , pp. 303-307
    • Khokha, M.K.1    Hsu, D.2    Brunet, L.J.3    Dionne, M.S.4    Harland, R.M.5
  • 8
    • 0034520158 scopus 로고    scopus 로고
    • Bone morphogenetic proteins induce gremlin, a protein that limits their activity in osteoblasts
    • Pereira R.C., Economides A.N., and Canalis E. Bone morphogenetic proteins induce gremlin, a protein that limits their activity in osteoblasts. Endocrinology 141 (2000) 4558-4563
    • (2000) Endocrinology , vol.141 , pp. 4558-4563
    • Pereira, R.C.1    Economides, A.N.2    Canalis, E.3
  • 9
    • 33749513921 scopus 로고    scopus 로고
    • Regulation of gremlin expression in the posterior limb bud
    • Nissim S., Hasso S.M., Fallon J.F., and Tabin C.J. Regulation of gremlin expression in the posterior limb bud. Dev. Biol. 299 (2006) 12-21
    • (2006) Dev. Biol. , vol.299 , pp. 12-21
    • Nissim, S.1    Hasso, S.M.2    Fallon, J.F.3    Tabin, C.J.4
  • 10
    • 48349106444 scopus 로고    scopus 로고
    • An Fgf/gremlin inhibitory feedback loop triggers termination of limb bud outgrowth
    • Verheyden J.M., and Sun X. An Fgf/gremlin inhibitory feedback loop triggers termination of limb bud outgrowth. Nature 454 (2008) 638-641
    • (2008) Nature , vol.454 , pp. 638-641
    • Verheyden, J.M.1    Sun, X.2
  • 11
    • 67651151629 scopus 로고    scopus 로고
    • Molecular regulation of limb growth
    • Lyons K., and Ezaki M. Molecular regulation of limb growth. J. Bone Joint Surg. Am. 91 Suppl. 4 (2009) 47-52
    • (2009) J. Bone Joint Surg. Am. , vol.91 , Issue.SUPPL. 4 , pp. 47-52
    • Lyons, K.1    Ezaki, M.2
  • 13
    • 3142714511 scopus 로고    scopus 로고
    • Tissue inhibitor of metalloproteinases-3 (TIMP-3) is a binding factor of epithelial growth-factor-containing fibulin-like extracellular matrix protein 1 (EFEMP 1). Implications for macular degenerations
    • Klenotic P.A., Munier F.L., Marmorstein L.Y., and Anand-Apte B. Tissue inhibitor of metalloproteinases-3 (TIMP-3) is a binding factor of epithelial growth-factor-containing fibulin-like extracellular matrix protein 1 (EFEMP 1). Implications for macular degenerations. J. Biol. Chem. 279 (2004) 30469-30473
    • (2004) J. Biol. Chem. , vol.279 , pp. 30469-30473
    • Klenotic, P.A.1    Munier, F.L.2    Marmorstein, L.Y.3    Anand-Apte, B.4
  • 16
    • 34548648492 scopus 로고    scopus 로고
    • Gene expression profiling of mouse articular and growth plate cartilage
    • Yamane S., Cheng E., You Z., and Reddi A.H. Gene expression profiling of mouse articular and growth plate cartilage. Tissue Eng. 13 (2007) 2163-2173
    • (2007) Tissue Eng. , vol.13 , pp. 2163-2173
    • Yamane, S.1    Cheng, E.2    You, Z.3    Reddi, A.H.4
  • 17
    • 0027494603 scopus 로고
    • Type IV collagen: structure, gene organization and role in human disease
    • Hudson B.G., Reeders S.T., and Tryggvason K. Type IV collagen: structure, gene organization and role in human disease. J. Biol. Chem. 268 (1993) 26033-26036
    • (1993) J. Biol. Chem. , vol.268 , pp. 26033-26036
    • Hudson, B.G.1    Reeders, S.T.2    Tryggvason, K.3
  • 18
    • 63249123741 scopus 로고    scopus 로고
    • Contactin-1 is a functional receptor for neuroregulatory chondroitin sulfate-e
    • Mikami T., Yasunaga D., and Kitagawa H. Contactin-1 is a functional receptor for neuroregulatory chondroitin sulfate-e. J. Biol. Chem. 284 7 (2009) 4494-4499
    • (2009) J. Biol. Chem. , vol.284 , Issue.7 , pp. 4494-4499
    • Mikami, T.1    Yasunaga, D.2    Kitagawa, H.3
  • 19
    • 0036645699 scopus 로고    scopus 로고
    • The chitinase 3-like protein human cartilage glycoprotein 39 (HC-gp39) stimulates proliferation of human connective-tissue cells and activates both extracellular signal-regulated kinase- and protein kinase B-mediated signaling pathways
    • Recklies A.D., White C., and Ling H. The chitinase 3-like protein human cartilage glycoprotein 39 (HC-gp39) stimulates proliferation of human connective-tissue cells and activates both extracellular signal-regulated kinase- and protein kinase B-mediated signaling pathways. Biochem. J. 365 (2002) 119-126
    • (2002) Biochem. J. , vol.365 , pp. 119-126
    • Recklies, A.D.1    White, C.2    Ling, H.3
  • 20
  • 21
    • 0033567396 scopus 로고    scopus 로고
    • Noncollagenous, nonproteoglycan macromolecules of cartilage
    • Neame P.J., Tapp H., and Azizan A. Noncollagenous, nonproteoglycan macromolecules of cartilage. Cell. Mol. Life Sci. 55 (1999) 1327-1340
    • (1999) Cell. Mol. Life Sci. , vol.55 , pp. 1327-1340
    • Neame, P.J.1    Tapp, H.2    Azizan, A.3
  • 22
    • 0028892460 scopus 로고
    • The primary structure of a basic leucine-rich repeat protein, PRELP, found in connective tissues
    • Bengtsson E., Neame P.J., Heinegard D., and Sommarin Y. The primary structure of a basic leucine-rich repeat protein, PRELP, found in connective tissues. J. Biol. Chem. 270 (1995) 25639-25644
    • (1995) J. Biol. Chem. , vol.270 , pp. 25639-25644
    • Bengtsson, E.1    Neame, P.J.2    Heinegard, D.3    Sommarin, Y.4
  • 23
    • 0033516558 scopus 로고    scopus 로고
    • The biology of the small leucine-rich proteoglycans
    • Iozzo R.V. The biology of the small leucine-rich proteoglycans. J. Biol. Chem. 274 (1999) 18843-18846
    • (1999) J. Biol. Chem. , vol.274 , pp. 18843-18846
    • Iozzo, R.V.1
  • 24
    • 0033580269 scopus 로고    scopus 로고
    • Vertebrate hedgehog signalling modulated by induction of a hedgehog-binding protein
    • Chuang P.-T., and McMahon A.P. Vertebrate hedgehog signalling modulated by induction of a hedgehog-binding protein. Nature 397 (1999) 617-621
    • (1999) Nature , vol.397 , pp. 617-621
    • Chuang, P.-T.1    McMahon, A.P.2
  • 26
    • 0035817632 scopus 로고    scopus 로고
    • Coordinated expression of matrix Gla protein is required during endochondral ossification for chondrocyte survival
    • Newman B., Gigout L.I., Sudre L., Grant M.E., and Wallis G.A. Coordinated expression of matrix Gla protein is required during endochondral ossification for chondrocyte survival. J. Cell Biol. 154 (2001) 659-666
    • (2001) J. Cell Biol. , vol.154 , pp. 659-666
    • Newman, B.1    Gigout, L.I.2    Sudre, L.3    Grant, M.E.4    Wallis, G.A.5
  • 27
    • 0035853783 scopus 로고    scopus 로고
    • Identification and characterization of asporin. A novel member of the leucine-rich repeat protein family closely related to decorin and biglycan
    • Lorenzo P., Asberg A., Onnerfjord P., Bayliss M.T., Neame P.J., and Heinegard D. Identification and characterization of asporin. A novel member of the leucine-rich repeat protein family closely related to decorin and biglycan. J. Biol. Chem. 276 (2001) 12201-12211
    • (2001) J. Biol. Chem. , vol.276 , pp. 12201-12211
    • Lorenzo, P.1    Asberg, A.2    Onnerfjord, P.3    Bayliss, M.T.4    Neame, P.J.5    Heinegard, D.6
  • 28
    • 52049122865 scopus 로고    scopus 로고
    • Biological function of the small leucine-rich proteoglycans: from genetics to signal transduction
    • Schaefer L., and Iozzo R.V. Biological function of the small leucine-rich proteoglycans: from genetics to signal transduction. J. Biol. Chem. 283 (2008) 21305-21309
    • (2008) J. Biol. Chem. , vol.283 , pp. 21305-21309
    • Schaefer, L.1    Iozzo, R.V.2
  • 30
    • 0040973727 scopus 로고    scopus 로고
    • The matrilins: a novel family of oligomeric extracellular matrix proteins
    • Deak F., Wagener R., Kiss I., and Paulsson M. The matrilins: a novel family of oligomeric extracellular matrix proteins. Matrix Biol. 18 (1999) 55-64
    • (1999) Matrix Biol. , vol.18 , pp. 55-64
    • Deak, F.1    Wagener, R.2    Kiss, I.3    Paulsson, M.4
  • 32
    • 13844315153 scopus 로고    scopus 로고
    • Microarray analysis of proliferative and hypertrophic growth plate zones identifies differentiation markers and signal pathways
    • Wang Y., Middleton F., Horton J.A., Reichel L., Farnum C.E., and Damron T.A. Microarray analysis of proliferative and hypertrophic growth plate zones identifies differentiation markers and signal pathways. Bone 35 (2004) 1273-1293
    • (2004) Bone , vol.35 , pp. 1273-1293
    • Wang, Y.1    Middleton, F.2    Horton, J.A.3    Reichel, L.4    Farnum, C.E.5    Damron, T.A.6
  • 33
    • 49149109033 scopus 로고    scopus 로고
    • Microarray analysis of perichondral and reserve growth plate zones identifies differential gene expressions and signal pathways
    • Zhang M., Pritchard M.R., Middleton F.A., Horton J.A., and Damron T.A. Microarray analysis of perichondral and reserve growth plate zones identifies differential gene expressions and signal pathways. Bone 43 3 (2008) 511-520
    • (2008) Bone , vol.43 , Issue.3 , pp. 511-520
    • Zhang, M.1    Pritchard, M.R.2    Middleton, F.A.3    Horton, J.A.4    Damron, T.A.5
  • 35
    • 34247348274 scopus 로고    scopus 로고
    • Gradients in bone morphogenetic protein-related gene expression across the growth plate
    • Nilsson O., Parker E.A., Hegde A., Chau M., Barnes K.M., and Baron J. Gradients in bone morphogenetic protein-related gene expression across the growth plate. J. Endocrinol. 193 1 (2007) 75-84
    • (2007) J. Endocrinol. , vol.193 , Issue.1 , pp. 75-84
    • Nilsson, O.1    Parker, E.A.2    Hegde, A.3    Chau, M.4    Barnes, K.M.5    Baron, J.6
  • 36
    • 43149102068 scopus 로고    scopus 로고
    • A microarray approach for comparative expression profiling of the discrete maturation zones of mouse growth plate cartilage
    • Belluoccio D., Bernardo B.C., Rowley L., and Bateman J.F. A microarray approach for comparative expression profiling of the discrete maturation zones of mouse growth plate cartilage. Biochim. Biophys. Acta 1779 (2008) 330-340
    • (2008) Biochim. Biophys. Acta , vol.1779 , pp. 330-340
    • Belluoccio, D.1    Bernardo, B.C.2    Rowley, L.3    Bateman, J.F.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.