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Volumn 6, Issue 6, 2009, Pages 893-902

Chemotherapy in the elderly: Are their needs being met?

Author keywords

Ageism; Aging; Cancer; Chemotherapy; Clinical trials; Comorbidity; Elderly; Pharmacokinetics; Pharmacology; Polypharmacy

Indexed keywords

ANTINEOPLASTIC AGENT; CYTOCHROME P450; PACLITAXEL;

EID: 70449652875     PISSN: 14750708     EISSN: 1744831X     Source Type: Journal    
DOI: 10.2217/thy.09.72     Document Type: Review
Times cited : (2)

References (116)
  • 1
    • 70449625899 scopus 로고    scopus 로고
    • Drug development in the elderly
    • Budman D, Calvert AH, Rowinsky EK (Eds). Lippincott Williams & Wilkins, PA, USA
    • Lichtman SM: Drug development in the elderly. In: Handbook of anticancer drug development. Budman D, Calvert AH, Rowinsky EK (Eds). Lippincott Williams & Wilkins, PA, USA, 411-423 (2004).
    • (2004) Handbook of Anticancer Drug Development , pp. 411-423
    • Lichtman, S.M.1
  • 3
    • 0038518557 scopus 로고    scopus 로고
    • Enrollment of older patients in cancer treatment trials in Canada: Why is age a barrier?
    • DOI 10.1200/JCO.2003.12.044
    • Yee KW, Pater JL, Pho L, Zee B, Siu LL: Enrollment of older patients in cancer treatment trials in Canada: why is age a barrier? J. Clin. Oncol. 21, 1618-1623. (2003). (Pubitemid 46594117)
    • (2003) Journal of Clinical Oncology , vol.21 , Issue.8 , pp. 1618-1623
    • Yee, K.W.L.1    Pater, J.L.2    Pho, L.3    Zee, B.4    Siu, L.L.5
  • 4
    • 16544371710 scopus 로고    scopus 로고
    • Enrollment of elderly patients in clinical trials for cancer drug registration: A 7-year experience by the US Food and Drug Administration
    • DOI 10.1200/JCO.2004.02.175
    • Talarico L, Chen G, Pazdur R: Enrollment of elderly patients in clinical trials for cancer drug registration: a 7-year experience by the US Food and Drug Administration. J. Clin. Oncol. 22, 4626-4631 (2004). (Pubitemid 41185131)
    • (2004) Journal of Clinical Oncology , vol.22 , Issue.22 , pp. 4626-4631
    • Talarico, L.1    Chen, G.2    Pazdur, R.3
  • 5
    • 34249811186 scopus 로고    scopus 로고
    • Older female cancer patients: Importance, causes, and consequences of undertreatment
    • Bouchardy C, Rapiti E, Blagojevic S, Vlastos AT, Vlastos G: Older female cancer patients: importance, causes, and consequences of undertreatment. J. Clin. Oncol. 25, 1858-1869 (2007).
    • (2007) J. Clin. Oncol. , vol.25 , pp. 1858-1869
    • Bouchardy, C.1    Rapiti, E.2    Blagojevic, S.3    Vlastos, A.T.4    Vlastos, G.5
  • 6
    • 9144246190 scopus 로고    scopus 로고
    • Drug development and use in the elderly: Search for the right dose and dosing regimen (Parts I and II)
    • Shah RR: Drug development and use in the elderly: search for the right dose and dosing regimen (Parts I and II). Br. J. Clin. Pharmacol. 58, 452-469 (2004).
    • (2004) Br. J. Clin. Pharmacol. , vol.58 , pp. 452-469
    • Shah, R.R.1
  • 8
    • 0037811742 scopus 로고    scopus 로고
    • Barriers to clinical trial participation by older women with breast cancer
    • Kemeny MM, Peterson BL, Kornblith AB et al.: Barriers to clinical trial participation by older women with breast cancer. J. Clin. Oncol. 21, 2268-2275 (2003).
    • (2003) J. Clin. Oncol. , vol.21 , pp. 2268-2275
    • Kemeny, M.M.1    Peterson, B.L.2    Kornblith, A.B.3
  • 9
    • 0036901268 scopus 로고    scopus 로고
    • Cognitive and functional decline in adults aged 75 and older
    • Black SA, Rush RD: Cognitive and functional decline in adults aged 75 and older. J. Am. Geriatr. Soc. 50, 1978-1986 (2002).
    • (2002) J. Am. Geriatr. Soc. , vol.50 , pp. 1978-1986
    • Black, S.A.1    Rush, R.D.2
  • 10
    • 0033008996 scopus 로고    scopus 로고
    • Toward an understanding of frailty
    • Hamerman D: Toward an understanding of frailty. Ann. Intern. Med. 130, 945-950 (1999).
    • (1999) Ann. Intern. Med. , vol.130 , pp. 945-950
    • Hamerman, D.1
  • 14
    • 0033955615 scopus 로고    scopus 로고
    • Management of the frail person with advanced cancer
    • DOI 10.1016/S1040-8428(99)00063-3, PII S1040842899000633
    • Balducci L, Extermann M: Management of the frail person with advanced cancer. Crit. Rev. Oncol. Hematol. 33, 143-148 (2000). (Pubitemid 30085478)
    • (2000) Critical Reviews in Oncology/Hematology , vol.33 , Issue.2 , pp. 143-148
    • Balducci, L.1    Extermann, M.2
  • 15
    • 67650315454 scopus 로고    scopus 로고
    • Supportive care in elderly cancer patients
    • Balducci L: Supportive care in elderly cancer patients. Curr. Opin. Oncol. 21, 310-317 (2009).
    • (2009) Curr. Opin. Oncol. , vol.21 , pp. 310-317
    • Balducci, L.1
  • 17
    • 0002518726 scopus 로고
    • Age differences in water content of the body as related to basal oxygen consumption in males
    • Shock NW, Watkin DM, Yiengst BS et al.: Age differences in water content of the body as related to basal oxygen consumption in males. J. Gerontol. 18, 1-8 (1963).
    • (1963) J. Gerontol. , vol.18 , pp. 1-8
    • Shock, N.W.1    Watkin, D.M.2    Yiengst, B.S.3
  • 18
    • 0014851083 scopus 로고
    • Adult lean body mass declines with age: Some longitudinal observations
    • Forbes GB, Reina JC: Adult lean body mass declines with age: some longitudinal observations. Metabolism 19, 653-663 (1978).
    • (1978) Metabolism , vol.19 , pp. 653-663
    • Forbes, G.B.1    Reina, J.C.2
  • 19
    • 49749191739 scopus 로고
    • Anatomy of body water and electrolytes
    • Adelman LS, Liebman J: Anatomy of body water and electrolytes. Am. J. Med. 27, 256-277 (1959).
    • (1959) Am. J. Med. , vol.27 , pp. 256-277
    • Adelman, L.S.1    Liebman, J.2
  • 20
    • 0025071032 scopus 로고
    • Altered pharmacokinetics in the elderly
    • Yuen GJ: Altered pharmacokinetics in the elderly. Clin. Geriatr. Med. 6, 257-267 (1990).
    • (1990) Clin. Geriatr. Med. , vol.6 , pp. 257-267
    • Yuen, G.J.1
  • 21
    • 0031057556 scopus 로고    scopus 로고
    • Pharmacology of cancer chemotherapy in the older person
    • Baker SD, Grochow LB: Pharmacology of cancer chemotherapy in the older person. Clin. Geriatr. Med. 13, 169-183 (1997).
    • (1997) Clin. Geriatr. Med. , vol.13 , pp. 169-183
    • Baker, S.D.1    Grochow, L.B.2
  • 22
    • 31544479321 scopus 로고    scopus 로고
    • Non-adherence to endocrine therapy for breast cancer
    • Partridge AH: Non-adherence to endocrine therapy for breast cancer. Ann. Oncol. 17, 183-184 (2006).
    • (2006) Ann. Oncol. , vol.17 , pp. 183-184
    • Partridge, A.H.1
  • 25
    • 0037441639 scopus 로고    scopus 로고
    • Nonadherence to adjuvant tamoxifen therapy in women with primary breast cancer
    • Partridge AH, Wang PS, Winer EP, Avorn J: Nonadherence to adjuvant tamoxifen therapy in women with primary breast cancer. J. Clin. Oncol. 21, 602-606 (2003).
    • (2003) J. Clin. Oncol. , vol.21 , pp. 602-606
    • Partridge, A.H.1    Wang, P.S.2    Winer, E.P.3    Avorn, J.4
  • 26
    • 58149097469 scopus 로고    scopus 로고
    • Anticancer drug therapy in the older cancer patient: Pharmacology and polypharmacy
    • Lichtman SM, Boparai MK: Anticancer drug therapy in the older cancer patient: pharmacology and polypharmacy. Curr. Treat. Options Oncol. 9, 191-203 (2008).
    • (2008) Curr. Treat. Options Oncol. , vol.9 , pp. 191-203
    • Lichtman, S.M.1    Boparai, M.K.2
  • 27
    • 0027529309 scopus 로고
    • Cancer pharmacology in the elderly
    • Egorin MJ: Cancer pharmacology in the elderly. Semin. Oncol. 20, 43-49 (1993).
    • (1993) Semin. Oncol. , vol.20 , pp. 43-49
    • Egorin, M.J.1
  • 28
    • 0004273857 scopus 로고
    • (2nd Edition). Lippincott, PA, USA, 704
    • Rossman I: Clinical geriatrics (2nd Edition). Lippincott, PA, USA, xxiii, 704 (1979).
    • (1979) Clinical Geriatrics
    • Rossman, I.1
  • 30
    • 0029824018 scopus 로고    scopus 로고
    • Relationship between toxicity and obesity in women receiving adjuvant chemotherapy for breast cancer: Results from cancer and leukemia group B study 8541
    • Rosner GL, Hargis JB, Hollis DR et al.: Relationship between toxicity and obesity in women receiving adjuvant chemotherapy for breast cancer: results from cancer and leukemia group B study 8541. J. Clin. Oncol. 14, 3000-3008 (1996).
    • (1996) J. Clin. Oncol. , vol.14 , pp. 3000-3008
    • Rosner, G.L.1    Hargis, J.B.2    Hollis, D.R.3
  • 31
    • 70449659612 scopus 로고    scopus 로고
    • 2: The experience from the program in Women's Oncology/ Brown Medical School
    • Abstract 5570
    • 2: the experience from the program in Women's Oncology/ Brown Medical School. J. Clin. Oncol. 26(Suppl.) (2008) (Abstract 5570).
    • (2008) J. Clin. Oncol. , vol.26 , Issue.SUPPL.
    • Schwartz, J.R.1    Toste, B.2    Dizon, D.S.3
  • 33
    • 0027965133 scopus 로고
    • Serum albumin level and physical disability as predictors of mortality in older persons
    • Corti MC, Guralnik JM, Salive ME, Sorkin JD: Serum albumin level and physical disability as predictors of mortality in older persons. JAMA 272, 1036-1042 (1994).
    • (1994) JAMA , vol.272 , pp. 1036-1042
    • Corti, M.C.1    Guralnik, J.M.2    Salive, M.E.3    Sorkin, J.D.4
  • 34
    • 0034807557 scopus 로고    scopus 로고
    • Depressed albumin and high-density lipoprotein cholesterol: Signposts along the final common pathway of frailty
    • Hazzard WR: Depressed albumin and high-density lipoprotein cholesterol: signposts along the final common pathway of frailty. J. Am. Geriatr. Soc. 49, 1253-1254 (2001).
    • (2001) J. Am. Geriatr. Soc. , vol.49 , pp. 1253-1254
    • Hazzard, W.R.1
  • 35
    • 0034807521 scopus 로고    scopus 로고
    • The value of serum albumin and high-density lipoprotein cholesterol in defining mortality risk in older persons with low serum cholesterol
    • DOI 10.1046/j.1532-5415.2001.49229.x
    • Volpato S, Leveille SG, Corti MC, Harris TB, Guralnik JM: The value of serum albumin and high-density lipoprotein cholesterol in defining mortality risk in older persons with low serum cholesterol. J. Am. Geriatr. Soc. 49, 1142-1147 (2001). (Pubitemid 32900139)
    • (2001) Journal of the American Geriatrics Society , vol.49 , Issue.9 , pp. 1142-1147
    • Volpato, S.1    Leveille, S.G.2    Corti, M.-C.3    Harris, T.B.4    Guralnik, J.M.5
  • 36
    • 0030931530 scopus 로고    scopus 로고
    • Aging and pharmacology
    • Vestal RE: Aging and pharmacology. Cancer 80, 1302-1310 (1997).
    • (1997) Cancer , vol.80 , pp. 1302-1310
    • Vestal, R.E.1
  • 38
    • 0020324688 scopus 로고
    • Dietary protein intake and the progressive nature of kidney disease: The role of hemodynamically mediated glomerular injury in the pathogenesis of progressive glomerular sclerosis in aging, renal ablation, and intrinsic renal disease
    • Brenner BM, Meyer GW, Hostetter TH: Dietary protein intake and the progressive nature of kidney disease: the role of hemodynamically mediated glomerular injury in the pathogenesis of progressive glomerular sclerosis in aging, renal ablation, and intrinsic renal disease. N. Engl. J. Med. 307, 652-659 (1982).
    • (1982) N. Engl. J. Med. , vol.307 , pp. 652-659
    • Brenner, B.M.1    Meyer, G.W.2    Hostetter, T.H.3
  • 39
    • 0014995132 scopus 로고
    • Age changes in the human kidney of the different races
    • Tauchi H, Tsuboi K, Okutoni J: Age changes in the human kidney of the different races. Gerontology 17, 87-97 (1971).
    • (1971) Gerontology , vol.17 , pp. 87-97
    • Tauchi, H.1    Tsuboi, K.2    Okutoni, J.3
  • 41
    • 0016916438 scopus 로고
    • Prediction of creatinine clearance from serum creatinine
    • Cockcroft DW, Gault MH: Prediction of creatinine clearance from serum creatinine. Nephron 16, 31-41 (1976).
    • (1976) Nephron , vol.16 , pp. 31-41
    • Cockcroft, D.W.1    Gault, M.H.2
  • 42
    • 0015215043 scopus 로고
    • Estimation of creatinine clearance when urine cannot be collected
    • Jelliffe RW: Estimation of creatinine clearance when urine cannot be collected. Lancet 1, 975-976 (1971).
    • (1971) Lancet , vol.1 , pp. 975-976
    • Jelliffe, R.W.1
  • 44
    • 0030924516 scopus 로고    scopus 로고
    • Cancer chemotherapy in the older patient: What the medical oncologist needs to knew
    • DOI 10.1002/(SICI)1097-0142(19971001)80:7<1317::AID-CNCR18>3.0. CO;2-A
    • Balducci L, Extermann M: Cancer chemotherapy in the older patient: what the medical oncologist needs to know. Cancer 80, 1317-1322 (1997). (Pubitemid 27407235)
    • (1997) Cancer , vol.80 , Issue.7 , pp. 1317-1322
    • Balducci, L.1    Extermann, M.2
  • 45
    • 0036234724 scopus 로고    scopus 로고
    • Pharmacokinetic considerations of oral chemotherapy in elderly patients with cancer
    • Skirvin JA, Lichtman SM: Pharmacokinetic considerations of oral chemotherapy in elderly patients with cancer. Drugs Aging 19, 25-42 (2002).
    • (2002) Drugs Aging , vol.19 , pp. 25-42
    • Skirvin, J.A.1    Lichtman, S.M.2
  • 46
    • 0028928599 scopus 로고
    • Anticancer drug renal toxicity and elimination: Dosing guidelines for altered renal function
    • Kintzel PE, Dorr RT: Anticancer drug renal toxicity and elimination: dosing guidelines for altered renal function. Cancer Treat. Rev. 21, 33-64 (1995).
    • (1995) Cancer Treat. Rev. , vol.21 , pp. 33-64
    • Kintzel, P.E.1    Dorr, R.T.2
  • 47
    • 34548787904 scopus 로고    scopus 로고
    • Prevalence of renal insufficiency in cancer patients and implications for anticancer drug management: The renal insufficiency and anticancer medications (IRMA) study
    • DOI 10.1002/cncr.22904
    • Launay-Vacher V, Oudard S, Janus N et al.: Prevalence of renal insufficiency in cancer patients and implications for anticancer drug management: the renal insufficiency and anticancer medications (IRMA) study. Cancer 110, 1376-1384 (2007). (Pubitemid 47435612)
    • (2007) Cancer , vol.110 , Issue.6 , pp. 1376-1384
    • Launay-Vacher, V.1    Oudard, S.2    Janus, N.3    Gligorov, J.4    Pourrat, X.5    Rixe, O.6    Morere, J.-F.7    Beuzeboc, P.8    Deray, G.9
  • 48
    • 51649090935 scopus 로고    scopus 로고
    • Cetuximab pharmacokinetics in end-stage kidney disease under hemodialysis
    • Thariat J, Azzopardi N, Peyrade F et al.: Cetuximab pharmacokinetics in end-stage kidney disease under hemodialysis. J. Clin. Oncol. 26, 4223-4225 (2008).
    • (2008) J. Clin. Oncol. , vol.26 , pp. 4223-4225
    • Thariat, J.1    Azzopardi, N.2    Peyrade, F.3
  • 49
    • 63249090524 scopus 로고    scopus 로고
    • Renal insufficiency and anticancer drugs in elderly cancer patients: A subgroup ana lysis of the IRMA study
    • Launay-Vacher V, Spano JP, Janus N et al.: Renal insufficiency and anticancer drugs in elderly cancer patients: a subgroup ana lysis of the IRMA study. Crit. Rev. Oncol. Hematol. 70, 124-133 (2009).
    • (2009) Crit. Rev. Oncol. Hematol. , vol.70 , pp. 124-133
    • Launay-Vacher, V.1    Spano, J.P.2    Janus, N.3
  • 50
    • 14944365826 scopus 로고    scopus 로고
    • Treatment of pain in patients with renal insufficiency: The World Health Organization three-step ladder adapted
    • DOI 10.1016/j.jpain.2004.11.009
    • Launay-Vacher V, Karie S, Fau JB, Izzedine H, Deray G: Treatment of pain in patients with renal insufficiency: the World Health Organization three-step ladder adapted. J. Pain 6, 137-148 (2005). (Pubitemid 40365017)
    • (2005) Journal of Pain , vol.6 , Issue.3 , pp. 137-148
    • Launay-Vacher, V.1    Karie, S.2    Fau, J.-B.3    Izzedine, H.4    Deray, G.5
  • 51
    • 33846049979 scopus 로고    scopus 로고
    • International Society of Geriatric Oncology (SIOG) recommendations for the adjustment of dosing in elderly cancer patients with renal insufficiency
    • DOI 10.1016/j.ejca.2006.11.004, PII S0959804906009907
    • Launay-Vacher V, Chatelut E, Lichtman S, Wildiers H, Steer C, Aapro M: Renal insufficiency in elderly cancer patients: International Society of Geriatric Oncology clinical practice recommendations. Ann. Oncol. 18, 1314-1321 (2007). (Pubitemid 46070218)
    • (2007) European Journal of Cancer , vol.43 , Issue.1 , pp. 14-34
    • Lichtman, S.M.1    Wildiers, H.2    Launay-Vacher, V.3    Steer, C.4    Chatelut, E.5    Aapro, M.6
  • 52
    • 38949167506 scopus 로고    scopus 로고
    • Clinical pharmacology of cancer therapies in older adults
    • DOI 10.1038/sj.bjc.6604201, PII 6604201
    • Hurria A, Lichtman SM: Clinical pharmacology of cancer therapies in older adults. Br. J. Cancer 98, 517-522 (2008). (Pubitemid 351214530)
    • (2008) British Journal of Cancer , vol.98 , Issue.3 , pp. 517-522
    • Hurria, A.1    Lichtman, S.M.2
  • 53
    • 34249779624 scopus 로고    scopus 로고
    • International Society of Geriatric Oncology Chemotherapy Taskforce: Evaluation of chemotherapy in older patients - An ana lysis of the medical literature
    • Lichtman SM, Wildiers H, Chatelut E et al.: International Society of Geriatric Oncology Chemotherapy Taskforce: evaluation of chemotherapy in older patients - an ana lysis of the medical literature. J. Clin. Oncol. 25, 1832-1843 (2007).
    • (2007) J. Clin. Oncol. , vol.25 , pp. 1832-1843
    • Lichtman, S.M.1    Wildiers, H.2    Chatelut, E.3
  • 54
    • 35148863196 scopus 로고    scopus 로고
    • Mastering chemotherapy dose reduction in elderly cancer patients
    • Wildiers H: Mastering chemotherapy dose reduction in elderly cancer patients. Eur. J. Cancer 43, 2235-2241 (2007).
    • (2007) Eur. J. Cancer , vol.43 , pp. 2235-2241
    • Wildiers, H.1
  • 55
    • 0023092594 scopus 로고
    • A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation
    • DOI 10.1016/0021-9681(87)90171-8
    • Charlson ME, Pompei P, Ales KL, MacKenzie CR: A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J. Chronic Dis. 40, 373-383 (1987). (Pubitemid 17055592)
    • (1987) Journal of Chronic Diseases , vol.40 , Issue.5 , pp. 373-383
    • Charlson, M.E.1    Pompei, P.2    Ales, K.A.3    MacKenzie, C.R.4
  • 56
    • 0032104347 scopus 로고    scopus 로고
    • Comorbidity and age as predictors of risk for early mortality of male and female colon carcinoma patients: A population-based study
    • DOI 10.1002/(SICI)1097-0142(19980601)82:11<2123::AID-CNCR6>3.0. CO;2-W
    • Yancik R, Wesley MN, Ries LA et al.: Comorbidity and age as predictors of risk for early mortality of male and female colon carcinoma patients: a population-based study. Cancer 82, 2123-2134 (1998). (Pubitemid 28240818)
    • (1998) Cancer , vol.82 , Issue.11 , pp. 2123-2134
    • Yancik, R.1    Wesley, M.N.2    Ries, L.A.G.3    Havlik, R.J.4    Long, S.5    Edwards, B.K.6    Yates, J.W.7
  • 57
    • 0028156819 scopus 로고
    • The effect of comorbidity on 3-year survival of women with primary breast cancer
    • Satariano WA, Ragland DA: The effect of comorbidity on 3-year survival of women with primary breast cancer. Ann. Intern. Med. 120, 104-110 (1994).
    • (1994) Ann. Intern. Med. , vol.120 , pp. 104-110
    • Satariano, W.A.1    Ragland, D.A.2
  • 59
    • 0032985575 scopus 로고    scopus 로고
    • A brief clinical instrument to classify frailty in elderly people
    • DOI 10.1016/S0140-6736(98)04402-X
    • Rockwood K, Stadnyk K, MacKnight C, McDowell I, Hebert R, Hogan DB: A brief clinical instrument to classify frailty in elderly people. Lancet 353, 205-206 (1999). (Pubitemid 29088034)
    • (1999) Lancet , vol.353 , Issue.9148 , pp. 205-206
    • Rockwood, K.1    Stadnyk, K.2    MacKnight, C.3    McDowell, I.4    Hebert, R.5    Hogan, D.B.6
  • 60
    • 0026440034 scopus 로고
    • Value of functional status as a predictor of mortality: Results of a prospective study
    • Reuben DB, Rubenstein LV, Hirsch SH, Hays RD: Value of functional status as a predictor of mortality: results of a prospective study. Am. J. Med. 93, 663-669 (1992).
    • (1992) Am. J. Med. , vol.93 , pp. 663-669
    • Reuben, D.B.1    Rubenstein, L.V.2    Hirsch, S.H.3    Hays, R.D.4
  • 62
    • 27244441470 scopus 로고    scopus 로고
    • Developing a cancer-specific geriatric assessment: A feasibility study
    • Hurria A, Gupta S, Zauderer M et al.: Developing a cancer-specific geriatric assessment: a feasibility study. Cancer 104, 1998-2005 (2005).
    • (2005) Cancer , vol.104 , pp. 1998-2005
    • Hurria, A.1    Gupta, S.2    Zauderer, M.3
  • 63
    • 55449083412 scopus 로고    scopus 로고
    • Functional assessment of the older patient with cancer
    • discussion 925, 928
    • Schubert CC, Gross C, Hurria A: Functional assessment of the older patient with cancer. Oncology (Williston Park) 22, 916-922; discussion 925, 928 (2008).
    • (2008) Oncology (Williston Park) , vol.22 , pp. 916-922
    • Schubert, C.C.1    Gross, C.2    Hurria, A.3
  • 64
    • 70449650631 scopus 로고    scopus 로고
    • Phase I study of Irinotecan (CPT-11) in patients with abnormal liver or renal function or with prior pelvic radiation therapy
    • Venook A, Klein C, Kastrissios H et al.: Phase I study of Irinotecan (CPT-11) in patients with abnormal liver or renal function or with prior pelvic radiation therapy. Proc. Annu. Meet. Am. Soc. Clin. Oncol. 20, A293 (2001).
    • (2001) Proc. Annu. Meet. Am. Soc. Clin. Oncol. , vol.20
    • Venook, A.1    Klein, C.2    Kastrissios, H.3
  • 65
    • 0031832839 scopus 로고    scopus 로고
    • Phase I and pharmacokinetic trial of paclitaxel in patients with hepatic dysfunction: Cancer and Leukemia Group B 9264
    • Venook AP, Egorin MJ, Rosner GL et al.: Phase I and pharmacokinetic trial of paclitaxel in patients with hepatic dysfunction: Cancer and Leukemia Group B 9264. J. Clin. Oncol. 16, 1811-1819 (1998).
    • (1998) J. Clin. Oncol. , vol.16 , pp. 1811-1819
    • Venook, A.P.1    Egorin, M.J.2    Rosner, G.L.3
  • 66
    • 18344416952 scopus 로고    scopus 로고
    • Phase I and pharmacokinetic trial of gemcitabine in patients with hepatic or renal dysfunction: Cancer and Leukemia Group B 9565
    • Venook AP, Egorin MJ, Rosner GL et al.: Phase I and pharmacokinetic trial of gemcitabine in patients with hepatic or renal dysfunction: Cancer and Leukemia Group B 9565. J. Clin. Oncol. 2780-2787 (2000).
    • (2000) J. Clin. Oncol. , pp. 2780-2787
    • Venook, A.P.1    Egorin, M.J.2    Rosner, G.L.3
  • 69
    • 64649083367 scopus 로고    scopus 로고
    • Phase I and pharmacokinetic study of sorafenib in patients with hepatic or renal dysfunction: CALGB 60301
    • Miller AA, Murry DJ, Owzar K et al.: Phase I and pharmacokinetic study of sorafenib in patients with hepatic or renal dysfunction: CALGB 60301. J. Clin. Oncol. 27, 1800-1805 (2009).
    • (2009) J. Clin. Oncol. , vol.27 , pp. 1800-1805
    • Miller, A.A.1    Murry, D.J.2    Owzar, K.3
  • 71
    • 33746298622 scopus 로고    scopus 로고
    • Impact of renal impairment on eligibility for adjuvant cisplatin-based chemotherapy in patients with urothelial carcinoma of the bladder
    • DOI 10.1002/cncr.22031
    • Dash A, Galsky MD, Vickers AJ et al.: Impact of renal impairment on eligibility for adjuvant cisplatin-based chemotherapy in patients with urothelial carcinoma of the bladder. Cancer 107, 506-513 (2006). (Pubitemid 44107210)
    • (2006) Cancer , vol.107 , Issue.3 , pp. 506-513
    • Dash, A.1    Galsky, M.D.2    Vickers, A.J.3    Serio, A.M.4    Koppie, T.M.5    Dalbagni, G.6    Bochner, B.H.7
  • 72
    • 0024270189 scopus 로고
    • The importance of age in survival of patients treated with chemotherapy for aggressive non-Hodgkin's lymphoma
    • Vose JM, Armitage JO, Weisenburger DD et al.: The importance of age in survival of patients treated with chemotherapy for aggressive non-Hodgkin's lymphoma. J. Clin. Oncol. 6, 1838-1844 (1988).
    • (1988) J. Clin. Oncol. , vol.6 , pp. 1838-1844
    • Vose, J.M.1    Armitage, J.O.2    Weisenburger, D.D.3
  • 78
    • 0018876664 scopus 로고
    • Aging, natural death, and the compression of morbidity
    • Fries JF: Aging, natural death, and the compression of morbidity. N. Engl. J. Med. 303, 130-135 (1980).
    • (1980) N. Engl. J. Med. , vol.303 , pp. 130-135
    • Fries, J.F.1
  • 79
    • 0141831175 scopus 로고    scopus 로고
    • Measuring and monitoring success in compressing morbidity
    • Fries JF: Measuring and monitoring success in compressing morbidity. Ann. Intern. Med. 139, 455-459 (2003).
    • (2003) Ann. Intern. Med. , vol.139 , pp. 455-459
    • Fries, J.F.1
  • 80
    • 8244254377 scopus 로고    scopus 로고
    • Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: A randomized trial
    • Burris HA, 3rd, Moore MJ, Andersen J et al.: Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial. J. Clin. Oncol. 15, 2403-2413 (1997).
    • (1997) J. Clin. Oncol. , vol.15 , pp. 2403-2413
    • Burris III, H.A.1    Moore, M.J.2    Andersen, J.3
  • 81
    • 4744366279 scopus 로고    scopus 로고
    • Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer
    • Tannock IF, de Wit R, Berry WR et al.: Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer. N. Engl. J. Med. 351, 1502-1512 (2004).
    • (2004) N. Engl. J. Med. , vol.351 , pp. 1502-1512
    • Tannock, I.F.1    De Wit, R.2    Berry, W.R.3
  • 83
    • 17444420107 scopus 로고    scopus 로고
    • A new paradigm for clinical investigation of infectious syndromes in older adults: Assessing functional status as a risk factor and outcome measure
    • DOI 10.1111/j.1532-5415.2005.53240.x
    • High K, Bradley S, Loeb M, Palmer R, Quagliarello V, Yoshikawa T: A new paradigm for clinical investigation of infectious syndromes in older adults: assessing functional status as a risk factor and outcome measure. J. Am. Geriatr. Soc. 53, 528-535 (2005). (Pubitemid 41623537)
    • (2005) Journal of the American Geriatrics Society , vol.53 , Issue.3 , pp. 528-535
    • High, K.1    Bradley, S.2    Loeb, M.3    Palmer, R.4    Quagliarello, V.5    Yoshikawa, T.6
  • 84
    • 66349117299 scopus 로고    scopus 로고
    • Comparisons of patient and physician expectations for cancer survivorship care
    • Cheung WY, Neville BA, Cameron DB, Cook EF, Earle CC: Comparisons of patient and physician expectations for cancer survivorship care. J. Clin. Oncol. 27, 2489-2495 (2009).
    • (2009) J. Clin. Oncol. , vol.27 , pp. 2489-2495
    • Cheung, W.Y.1    Neville, B.A.2    Cameron, D.B.3    Cook, E.F.4    Earle, C.C.5
  • 85
    • 34548527018 scopus 로고    scopus 로고
    • Cancer survivorship research and guidelines: Maybe the cart should be beside the horse
    • Earle CC: Cancer survivorship research and guidelines: maybe the cart should be beside the horse. J. Clin. Oncol. 25, 3800-3801 (2007).
    • (2007) J. Clin. Oncol. , vol.25 , pp. 3800-3801
    • Earle, C.C.1
  • 86
    • 33947173857 scopus 로고    scopus 로고
    • Cancer survivorship: A new challenge in delivering quality cancer care
    • DOI 10.1200/JCO.2006.09.2700
    • Rowland JH, Hewitt M, Ganz PA: Cancer survivorship: a new challenge in delivering quality cancer care. J. Clin. Oncol. 24, 5101-5104 (2006). (Pubitemid 46623194)
    • (2006) Journal of Clinical Oncology , vol.24 , Issue.32 , pp. 5101-5104
    • Rowland, J.H.1    Hewitt, M.2    Ganz, P.A.3
  • 87
    • 0037249412 scopus 로고    scopus 로고
    • Pegfilgrastim: The promise of pegylation fulfilled
    • Crawford J: Pegfilgrastim: the promise of pegylation fulfilled. Ann. Oncol. 14, 6-7 (2003).
    • (2003) Ann. Oncol. , vol.14 , pp. 6-7
    • Crawford, J.1
  • 88
    • 0025800331 scopus 로고
    • Reduction by granulocyte colony-stimulating factor of fever and neutropenia induced by chemotherapy in patients with small-cell lung cancer
    • Crawford J, Ozer H, Stoller R et al.: Reduction by granulocyte colony-stimulating factor of fever and neutropenia induced by chemotherapy in patients with small-cell lung cancer. N. Engl. J. Med. 325, 164-170 (1991).
    • (1991) N. Engl. J. Med. , vol.325 , pp. 164-170
    • Crawford, J.1    Ozer, H.2    Stoller, R.3
  • 89
    • 0035281526 scopus 로고    scopus 로고
    • Patients aged > or =70 are at high risk for neutropenic infection and should receive hemopoietic growth factors when treated with moderately toxic chemotherapy [2] (multiple letters)
    • Balducci L, Lyman GH: Patients aged > or =70 are at high risk for neutropenic infection and should receive hemopoietic growth factors when treated with moderately toxic chemotherapy. J. Clin. Oncol. 19, 1583-1585 (2001). (Pubitemid 32202566)
    • (2001) Journal of Clinical Oncology , vol.19 , Issue.5 , pp. 1583-1584
    • Balducci, L.1    Lyman, G.H.2    Ozer, H.3
  • 91
    • 23544474815 scopus 로고    scopus 로고
    • Toxicology by organ system
    • Holland JF, Frei E (Eds). BC Decker, NY, USA
    • Grever MR, Grieshaber CK: Toxicology by organ system. In: Cancer medicine. Holland JF, Frei E (Eds). BC Decker, NY, USA (2000).
    • (2000) Cancer Medicine
    • Grever, M.R.1    Grieshaber, C.K.2
  • 92
    • 70449629945 scopus 로고    scopus 로고
    • Geriatric medication management: Evaluation of pharmacist interventions and potentially inappropriate medication (PIM) use in older (≥65 years) cancer patients
    • Abstract 9507
    • Lichtman SM, Boparai M: Geriatric medication management: evaluation of pharmacist interventions and potentially inappropriate medication (PIM) use in older (≥65 years) cancer patients. J. Clin. Oncol. 27(Suppl.), S15 (2009) (Abstract 9507).
    • (2009) J. Clin. Oncol. , vol.27 , Issue.SUPPL.
    • Lichtman, S.M.1    Boparai, M.2
  • 93
    • 0029582977 scopus 로고
    • The role of human cytochrome P450 enzymes in the metabolism of anticancer agents: Implications for drug interactions
    • Kivisto KT, Kroemer HK, Eichelbaum M: The role of human cytochrome P450 enzymes in the metabolism of anticancer agents: implications for drug interactions. Br. J. Clin. Pharmacol. 40, 523-530 (1995).
    • (1995) Br. J. Clin. Pharmacol. , vol.40 , pp. 523-530
    • Kivisto, K.T.1    Kroemer, H.K.2    Eichelbaum, M.3
  • 94
    • 0028896781 scopus 로고
    • Drug interactions with cancer chemotherapy
    • King RS: Drug interactions with cancer chemotherapy. Cancer Pract. 3, 57-59 (1995).
    • (1995) Cancer Pract. , vol.3 , pp. 57-59
    • King, R.S.1
  • 95
    • 0037169960 scopus 로고    scopus 로고
    • Implications of cytochrome P450 interactions when prescribing medication for hypertension
    • Flockhart DA, Tanus-Santos JE: Implications of cytochrome P450 interactions when prescribing medication for hypertension. Arch. Intern. Med. 162, 405-412 (2002).
    • (2002) Arch. Intern. Med. , vol.162 , pp. 405-412
    • Flockhart, D.A.1    Tanus-Santos, J.E.2
  • 97
    • 0030061851 scopus 로고    scopus 로고
    • Limited sampling model for area under the concentration time curve of total topotecan
    • Minami H, Beijnen JH, Verweij J, Ratain MJ: Limited sampling model for area under the concentration time curve of total topotecan. Clin. Cancer Res. 2, 43-46 (1996). (Pubitemid 26042177)
    • (1996) Clinical Cancer Research , vol.2 , Issue.1 , pp. 43-46
    • Minami, H.1    Beijnen, J.H.2    Verweij, J.3    Ratain, M.J.4
  • 98
    • 0029902106 scopus 로고    scopus 로고
    • Limited-sampling models for irinotecan pharmacokinetics- Pharmacodynamics: Prediction of biliary index and intestinal toxicity
    • Mick R, Gupta E, Vokes EE, Ratain MJ: Limited-sampling models for irinotecan pharmacokinetics-pharmacodynamics: prediction of biliary index and intestinal toxicity. J. Clin. Oncol. 14, 2012-2019 (1996). (Pubitemid 26230101)
    • (1996) Journal of Clinical Oncology , vol.14 , Issue.7 , pp. 2012-2019
    • Mick, R.1    Gupta, E.2    Vokes, E.E.3    Ratain, M.J.4
  • 99
    • 0025910997 scopus 로고
    • Limited sampling models for doxorubicin pharmacokinetics
    • Ratain MJ, Robert J, van der Vijgh WJ: Limited sampling models for doxorubicin pharmacokinetics. J. Clin. Oncol. 9, 871-876 (1991).
    • (1991) J. Clin. Oncol. , vol.9 , pp. 871-876
    • Ratain, M.J.1    Robert, J.2    Van Der Vijgh, W.J.3
  • 101
    • 0023752701 scopus 로고
    • Limited sampling models for amonafide (NSC 308847) pharmacokinetics
    • Ratain MJ, Staubus AE, Schilsky RL, Malspeis L: Limited sampling models for amonafide (NSC 308847) pharmacokinetics. Cancer Res. 48, 4127-4130 (1988).
    • (1988) Cancer Res. , vol.48 , pp. 4127-4130
    • Ratain, M.J.1    Staubus, A.E.2    Schilsky, R.L.3    Malspeis, L.4
  • 102
    • 0023199545 scopus 로고
    • Limited sampling model for vinblastine pharmacokinetics
    • Ratain MJ, Vogelzang NJ: Limited sampling model for vinblastine pharmacokinetics. Cancer Treat. Rep. 71, 935-939 (1987).
    • (1987) Cancer Treat. Rep. , vol.71 , pp. 935-939
    • Ratain, M.J.1    Vogelzang, N.J.2
  • 106
    • 0025836658 scopus 로고
    • Population pharmacokinetics: Theory and practice
    • Aarons L: Population pharmacokinetics: theory and practice. Br. J. Clin. Pharmacol. 32, 669-670 (1991).
    • (1991) Br. J. Clin. Pharmacol. , vol.32 , pp. 669-670
    • Aarons, L.1
  • 107
    • 33646366957 scopus 로고    scopus 로고
    • Prospective evaluation of the relationship of patient age and paclitaxel clinical pharmacology: Cancer and Leukemia Group B (CALGB 9762)
    • Lichtman SM, Hollis D, Miller AA et al.: Prospective evaluation of the relationship of patient age and paclitaxel clinical pharmacology: Cancer and Leukemia Group B (CALGB 9762). J. Clin. Oncol. 24, 1846-1851 (2006).
    • (2006) J. Clin. Oncol. , vol.24 , pp. 1846-1851
    • Lichtman, S.M.1    Hollis, D.2    Miller, A.A.3
  • 108
    • 65649108950 scopus 로고    scopus 로고
    • Adjuvant chemotherapy in older women with early-stage breast cancer
    • Muss HB, Berry DA, Cirrincione CT et al.: Adjuvant chemotherapy in older women with early-stage breast cancer. N. Engl. J. Med. 360, 2055-2065 (2009).
    • (2009) N. Engl. J. Med. , vol.360 , pp. 2055-2065
    • Muss, H.B.1    Berry, D.A.2    Cirrincione, C.T.3
  • 110
    • 0035448972 scopus 로고    scopus 로고
    • Who gets adjuvant treatment for stage II and III rectal cancer? Insight from surveillance, epidemiology, and end results-medicare
    • Schrag D, Gelfand SE, Bach PB, Guillem J, Minsky BD, Begg CB: Who gets adjuvant treatment for stage II and III rectal cancer? Insight from surveillance, epidemiology, and end results - Medicare. J. Clin. Oncol. 19, 3712-3718 (2001). (Pubitemid 32844782)
    • (2001) Journal of Clinical Oncology , vol.19 , Issue.17 , pp. 3712-3718
    • Schrag, D.1    Gelfand, S.E.2    Bach, P.B.3    Guillem, J.4    Minsky, B.D.5    Begg, C.B.6
  • 111
    • 60749088710 scopus 로고    scopus 로고
    • Geriatric assessment in older patients with breast cancer
    • Klepin H, Mohile S, Hurria A: Geriatric assessment in older patients with breast cancer. J. Natl Compr. Canc. Netw. 7, 226-236 (2009).
    • (2009) J. Natl Compr. Canc. Netw. , vol.7 , pp. 226-236
    • Klepin, H.1    Mohile, S.2    Hurria, A.3
  • 112
    • 79953865459 scopus 로고    scopus 로고
    • Geriatric assessment of older adults with cancer: Baseline data from a 500 patient multicenter study
    • Abstract 9546
    • Hurria A, Mohile S, Lichtman S et al.: Geriatric assessment of older adults with cancer: baseline data from a 500 patient multicenter study. J. Clin. Oncol. 27(Suppl.), S15 (2009) (Abstract 9546).
    • (2009) J. Clin. Oncol. , vol.27 , Issue.SUPPL.
    • Hurria, A.1    Mohile, S.2    Lichtman, S.3
  • 113
    • 56749173731 scopus 로고    scopus 로고
    • Role of age and health in treatment recommendations for older adults with breast cancer: The perspective of oncologists and primary care providers
    • Hurria A, Wong FL, Villaluna D et al.: Role of age and health in treatment recommendations for older adults with breast cancer: the perspective of oncologists and primary care providers. J. Clin. Oncol. 26, 5386-5392 (2008).
    • (2008) J. Clin. Oncol. , vol.26 , pp. 5386-5392
    • Hurria, A.1    Wong, F.L.2    Villaluna, D.3
  • 115
    • 0035145055 scopus 로고    scopus 로고
    • Life expectancy, comorbidity and quality of life: The treatment equation in the older cancer patients
    • DOI 10.1016/S1040-8428(00)00104-9, PII S1040842800001049
    • Repetto L, Comandini D, Mammoliti S: Life expectancy, comorbidity and quality of life: the treatment equation in the older cancer patients. Crit. Rev. Oncol. Hematol. 37, 147-152 (2001). (Pubitemid 32109222)
    • (2001) Critical Reviews in Oncology/Hematology , vol.37 , Issue.2 , pp. 147-152
    • Repetto, L.1    Comandini, D.2    Mammoliti, S.3
  • 116
    • 18444383684 scopus 로고    scopus 로고
    • Population-based validation of the prognostic model ADJUVANT! for early breast cancer
    • Olivotto IA, Bajdik CD, Ravdin PM et al.: Population-based validation of the prognostic model ADJUVANT! for early breast cancer. J. Clin. Oncol. 23, 2716-2725 (2005).
    • (2005) J. Clin. Oncol. , vol.23 , pp. 2716-2725
    • Olivotto, I.A.1    Bajdik, C.D.2    Ravdin, P.M.3


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