Memory improving and antidepressant effects of topiramate in rats

Arzneimittel-Forschung/Drug Research

Volumn 59, Issue 10, 2009, Pages 487-492

  Nowakowska, Elzbieta ^a   Kus, Krzysztof ^a   Czubak, Anna ^a   Jedrzejewska, Joanna ^a  

^a POZNAN UNIVERSITY OF MEDICAL SCIENCES   (Poland)

Author keywords

Antidepressant effect; Antiepileptic drug; CAS 97240 79 4; Memory function; Normothymic drug; Rats; Topiramate

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; ANTIDEPRESSANT AGENT; CAS 97240 79 4; GLUTAMATE RECEPTOR; TOPIRAMATE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATTENTION; BIPOLAR DEPRESSION; BIPOLAR DISORDER; CODING; CONTROLLED STUDY; DEPRESSION; DRUG EFFECT; DRUG EFFICACY; DRUG POTENTIATION; EPILEPSY; LONG TERM CARE; MALE; MEMORY; MEMORY DISORDER; NONHUMAN; RAT; REPEATED DRUG DOSE; SEIZURE; SINGLE DRUG DOSE; SPATIAL MEMORY;

EID: 70449652874     PISSN: 00044172     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0031-1296431     Document Type: Article

References (44)

1. Aldenkamp AP, De Krom M, Rejs R. Newer antiepileptic drugs and cognitive issues. Epilepsia. 2003;44:21-29 (Pubitemid 36842173)
2. Amann B, Grunze H. Neurochemical Underpinnings in Bipolar Disorder and Epilepsy. Epilepsia. 2005;46:26-30. (Pubitemid 40847380)
3. Arnone D. Review of the use of Topiramate for treatment of psychiatric disorders. Ann Gen Psychiatry. 2005;4:1-14. (Pubitemid 40854397)
4. Barton ME, Klein BD, Wolf HH, White HS. Pharmacological characterization of the 6 Hz psychomotor seizure model of partial epilepsy. Epilepsy Res. 2001;47:217-227
5. Beghi E. Efficacy and tolerability of the new antiepileptic drugs: comparison of two recent guidelines. Lancet Neurol. 2004;3:618-621 (Pubitemid 39221928)
6. Berlant J, van Kammen DP. Open-label topiramate as primary or adjunctive therapy in chronic civilian posttraumatic stress disorder: a preliminary report. J Clin Psychiatry. 2002;63:15-20. (Pubitemid 34113481)
7. Berlant JL. Topiramate in posttraumatic stress disorder: preliminary clinical observations. J Clin Psychiatry. 2001;62:60-63 (Pubitemid 32720668)
8. Burton LA, Harden C. Effect of topiramate on attention. Epilepsy Res. 1997;27:29-32.
9. Carlson GA. Bipolar Disorder. In: Martin A, Scahill L, Charney D, Leckman J, editors. W. Pediatric Psychopharmacology. New York (NY): Oxford University Press; 2003. p. 484-496.
10. Chengappa KN, Rathore D, Levine J, Atzert R, Solai L, Parepally H, et al. Topiramat as add-on treatment for patients with bipolar disorder. Bipolar Disord. 1999;1:42-53.
11. Chengappa KN, Rathore D, Levine J, editors. World Congress of Psychiatry. Presented at the 11th World Congress of Psychiatry; 1999 August 8; Hamburg, Germany.
12. Follett PL, Deng W, Dai W, Talos DM, Massillon LJ, Rosenberg PA, et al. Glutamate receptor-mediated oligodendrocyte toxicity in periventricular leukomalacia: a protective role for topiramate. J Neurosci. 2004;5:4412-4420 (Pubitemid 38608152)
13. Grabowska-Grzyb A. Psychotropowe działanie leków przeciwpadaczkowych. Terapia. 2006;1:174.
14. Hargreaves GA, McGregor IS. Topiramate moderately reduces the motivation to consume alcohol and has a marked antidepressant effect in rats. Alcohol Clin Exp Res. 2007;31:1900-1907
15. Hoover RC, Motta M, Davis J, Saatman KE, Fujimoto ST, Thompson HJ, et al. Differential effects of the anticonvulsant topiramate on neurobehavioral and histological outcomes following traumatic brain in rats. J Neurotrauma. 2004;21:501-512 (Pubitemid 38656748)
16. Husum H, Van Kammen D, Termeer E, Bolwig G, Mathé A. Topiramate normalizes hippocampal NPY-LI in flinders sensitive line 'depressed' rats and upregulates NPY, galanin, and CRH-LI in the hypothalamus: implications for mood-stabilizing and weight loss-inducing effects. Neuropsychopharmacology. 2003;28:1292-1299
17. Kockelmann E, Elger CE, Helmstaedter C. Significant improvement in frontal lobe associated neuropsychological functions after withdrawal of topiramate in epilepsy patients. Epilepsy Res. 2003;54:171-178 (Pubitemid 36776735)
18. Marcotte D. Use of topiramate, a new anti-epileptic as a mood stabilizer. J Affect Disord. 1998;50:245-251 (Pubitemid 28551793)
19. Martin R, Kuzniecky R, Ho S, Hetherington H, Pan J, Sinclair K, et al. Cognitive effects of topiramate, gabapentin, and lamotrigine in healthy young adults. Neurology. 1999;52:321-327 (Pubitemid 29059059)
20. Martin RC, Griffith HR, Faught E, Gilliam F, Mackey M, Vogtle L. Cognitive functioning in community dwelling older adults with chronic partial epilepsy. Epilepsia. 2005;46:298-303. (Pubitemid 40194674)
21. Martins de Lima MN, Presti-Torres J, Dornelles A, Bromberg E, Schroder N. Differential effects of low and high doses if topiramate on consolidation and retrieval of novel object recognition memory in rats. Epilepsy Behav. 2007;10:32-37 (Pubitemid 46132162)
22. McIntyre RS, Mancini DA, McCann S, Srinivasan J, Sagman D, Kennedy SH. Topiramate versus Buspirone SR when added to mood stabilizer therapy for the depressive phase of bipolar disorder: a preliminary single-blind study. Bipolar Dis. 2002;4:207-213 (Pubitemid 34591247)
23. Meador KJ, Loring DW, Ray PG, Murro AM, King DW, Nichols ME, et al. Differential cognitive effects of carbamazepine and gabapentin. Epilepsia. 1999;40:1279-1285
24. Morris R. Development of a water-maze procedure for studying spatial learning in a rat. J Neurosc Methods. 1984;11:47-60. (Pubitemid 14088970)
25. Mula M, Trimble MR, Thompson P, Sander JW. Topiramate and word-finding difficulties in patients with epilepsy. Neurology. 2003;60:1104-1107 (Pubitemid 36418768)
26. Nowakowska E, Chodera A, Kus K. An anxiolytic-like effect of ondansetron disappears oxazepam tolerant rats. Pharmacol Biochem Behav. 1998;59:935-938 (Pubitemid 28237906)
27. Nowakowska E, Chodera A, Kus K. Influence of olanzapine on cognitive function and catalepsy in rats after single and chronic administration. Pol J Pharmacol. 1999;51:295-300. (Pubitemid 29415643)
28. Nowakowska E, Kus K, Czubak A, Glowacka D, Matschay A. Some behavioural effects of carbamazepine - comparison with haloperidol. J Physiol Pharmacol. 2007;58:253-264 (Pubitemid 47026560)
29. Ortinski P, Meador KJ. Cognitive side effects on antiepileptic drugs. Epilepsy Behav. 2004;5:60-65 (Pubitemid 38937084)
30. Porsolt RD, Anton G, Blavet N, Jalfre M. Behavioural despair in rats: a new model sensitive to antidepressant treatments. Eur J Pharmacol. 1978;47:379-391
31. Poulsen CF, Simeone TA, Maar TE, Smith-Swintosky V, White HS, Schousboe A. Modulation by topiramate of AMPA and kainate mediated calcium influx in cultured cerebral cortical, hippocampal and cerebellar neurons. Neurochem Res. 2004;29:275-282 (Pubitemid 38181721)
32. Richardson JS, Hertzl L. The effects of antidepressant drugs on adenylyl cyclase linked beta adrenergic binding sites on mouse astrocytes in primary cultures. Prog Neuropsychopharmacol Biol Psychiatry. 1983;7:675-680
33. Sachdeo RC, Reife RA, Lim P. Topiramate monotherapy for partial onset seizure. Epilepsia. 1997;38:294-300. (Pubitemid 27147642)
34. Sankar R, Holmes GL. Mechanisms of action for the commonly used antiepileptic drugs: relevance to antiepileptic drug-associated neurobehavioral adverse effects. J Child Neurol. 2004;19:6-14. (Pubitemid 39480766)
35. Shannon HE, Eberle EL, Peters SC. Comparison of the effects of antiepileptic drugs with diverse mechanisms of action in the formalin test in rats. Neuropsychopharmacol. 2005;48:1012-1020
36. Shannon HE, Love PL. Effects of antiepileptic drugs on attention as assessed by a five-choice serial reaction time task in rats. Epilepsy Behav. 2005;7:620-628
37. Shannon HE, Love PL. Effects of antiepileptic drugs on working memory as assessed by spatial alternation performance in rats. Epilepsy Behav. 2004;5:857-865
38. Stefan H, Feuerstein TJ. Novel anticonvulsant drugs. Pharmacol Therap. 2007;113:165-183
39. White HS, Brown SD, Woodhead JH, Skeen GA, Wolf HH. Topiramate enhances GABA-mediated chloride flux and GABA-evoked chloride currents in murine brain neurons and increases seizure threshold. Epilepsy Res. 1997;28:167-179
40. White HS, Brown SD, Woodhead JH, Skeen GA, Wolf HH. Topiramate modulates GABA-evoked currents in murine cortical neurons by a nonbenzodiazepine mechanism. Epilepsia. 2000;41:17-20.
41. th World Congress of Psychiatry; 1999 August 11; Hamburg, Germany.
42. Zaccara G, Messori A, Cincotta M, Burchini G. Comparison of the efficacy and tolerability of new antiepileptic drugs: what can we learn from long-term studies? Acta Neurol Scan. 2006;114:157-168
43. Zhang X, Velumian AA, Jones OT, Carlen PL. Modulation of high-voltage-activated calcium channels in dentate granule cells by topiramate. Epilepsia. 2000;41:52-60. (Pubitemid 30202343)
44. Zona C, Ciotti MT, Avoli M. Topiramate attenuates voltage-gated sodium currents in rat cerebellar granule cell. Neurosc Letters. 1997;231:123-126 (Pubitemid 27381929)