메뉴 건너뛰기




Volumn 87, Issue 12, 2009, Pages 2812-2820

Simultaneous efflux of endogenous D-ser and L-glu from single acute hippocampus slices during oxygen glucose deprivation

Author keywords

Capillary electrophoresis; Cardiac arrest; D serine; Excitotoxicity; Ischemia; L glutamate; Microperfusion; Stroke

Indexed keywords

ASPARTIC ACID; DEXTRO SERINE; GLUTAMINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; THREONINE;

EID: 70449640288     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.22092     Document Type: Article
Times cited : (15)

References (40)
  • 1
    • 1842558602 scopus 로고    scopus 로고
    • Molecular mechanisms of glutamate-dependent neurodegeneration in ischemia and traumatic brain injury
    • DOI 10.1007/s00018-003-3319-x
    • Arundine M, Tymianski M. 2004. Molecular mechanisms of glutamate-dependent neurodegeneration in ischemia and traumatic brain injury. Cell Mol Life Sci 61:657-668. (Pubitemid 38446410)
    • (2004) Cellular and Molecular Life Sciences , vol.61 , Issue.6 , pp. 657-668
    • Arundine, M.1    Tymianski, M.2
  • 2
    • 0021707433 scopus 로고
    • Elevation of the extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis
    • DOI 10.1111/j.1471-4159.1984.tb05396.x
    • Benveniste H, Drejer J, Schousboe A, Diemer NH. 1984. Elevation of the extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis. J Neurochem 43:1369-1374. (Pubitemid 15205893)
    • (1984) Journal of Neurochemistry , vol.43 , Issue.5 , pp. 1369-1374
    • Benveniste, H.1    Drejer, J.2    Schousboe, A.3    Diemer, N.H.4
  • 3
    • 29244457820 scopus 로고    scopus 로고
    • Measuring the effect of glutamate receptor agonists on extracellular D-serine concentrations in the rat striatum using online microdialysis-capillary electrophoresis
    • Ciriacks CM, Bowser MT. 2006. Measuring the effect of glutamate receptor agonists on extracellular D-serine concentrations in the rat striatum using online microdialysis-capillary electrophoresis. Neurosci Lett 393:200-205.
    • (2006) Neurosci Lett , vol.393 , pp. 200-205
    • Ciriacks, C.M.1    Bowser, M.T.2
  • 4
    • 0030592811 scopus 로고    scopus 로고
    • Single-channel evidence for glycine and NMDA requirement in NMDA receptor activation
    • Curras MC, Pallotta BS. 1996. Single-channel evidence for glycine and NMDA requirement in NMDA receptor activation. Brain Res 740:27-40.
    • (1996) Brain Res , vol.740 , pp. 27-40
    • Curras, M.C.1    Pallotta, B.S.2
  • 5
    • 0034515275 scopus 로고    scopus 로고
    • Characterization of transient focal ischemia-induced increases in extracellular glutamate and aspartate in spontaneously hypertensive rats
    • DOI 10.1016/S0361-9230(00)00363-4, PII S0361923000003634
    • Dawson LA, Djali S, Gonzales C, Vinegra MA, Zaleska MM. 2000. Characterization of transient focal ischemia-induced increases in extracellular glutamate and aspartate in spontaneously hypertensive rats. Brain Res Bull 53:767-776. (Pubitemid 32120281)
    • (2000) Brain Research Bulletin , vol.53 , Issue.6 , pp. 767-776
    • Dawson, L.A.1    Djali, S.2    Gonzales, C.3    Vinegra, M.A.4    Zaleska, M.M.5
  • 6
    • 11844253187 scopus 로고    scopus 로고
    • Simultaneous determination of D- And L-serine in rat brain microdialysis sample using a column-switching HPLC with fluorimetric detection
    • Fukushima T, Kawai J, Imai K, Toyo'oka T. 2004. Simultaneous determination of D- and L-serine in rat brain microdialysis sample using a column-switching HPLC with fluorimetric detection. Biomed Chromatogr 18:813-819.
    • (2004) Biomed Chromatogr , vol.18 , pp. 813-819
    • Fukushima, T.1    Kawai, J.2    Imai, K.3    Toyo'oka, T.4
  • 8
    • 0030850891 scopus 로고    scopus 로고
    • Free D-aspartate and D-serine in the mammalian brain and periphery
    • DOI 10.1016/S0301-0082(97)00019-1, PII S0301008297000191
    • Hashimoto A, Oka T. 1997. Free D-aspartate and D-serine in the mammalian brain and periphery. Prog Neurobiol 52:325-353. (Pubitemid 27307050)
    • (1997) Progress in Neurobiology , vol.52 , Issue.4 , pp. 325-353
    • Hashimoto, A.1    Oka, T.2
  • 9
    • 0029156742 scopus 로고
    • Anatomical distribution and postnatal changes in endogenous free D-aspartate and D-serine in rat brain and periphery
    • Hashimoto A, Oka T, Nishikawa T. 1995. Anatomical distribution and postnatal changes in endogenous free D-aspartate and D-serine in rat brain and periphery. Eur J Neurosci 7:1657-1663.
    • (1995) Eur J Neurosci , vol.7 , pp. 1657-1663
    • Hashimoto, A.1    Oka, T.2    Nishikawa, T.3
  • 10
    • 0028852760 scopus 로고
    • Neuroprotective effect of phenylsuccinate, an inhibitor of cytosolic glutamate formation from glutamine, under anoxic conditions but not during exposure to exogenous glutamate
    • Huang R, Hertz L. 1995a. Neuroprotective effect of phenylsuccinate, an inhibitor of cytosolic glutamate formation from glutamine, under anoxic conditions but not during exposure to exogenous glutamate. Neurosci Lett 183:22-26.
    • (1995) Neurosci Lett , vol.183 , pp. 22-26
    • Huang, R.1    Hertz, L.2
  • 11
    • 0029589738 scopus 로고
    • + of anoxic release of newly synthesized neuronal glutamate
    • + of anoxic release of newly synthesized neuronal glutamate. Neuroreport 6:2404-2408.
    • (1995) Neuroreport , vol.6 , pp. 2404-2408
    • Huang, R.1    Hertz, L.2
  • 12
    • 0027268569 scopus 로고
    • Time-related loss of glutamine from hippocampal slices and concomitant changes in neurotransmitter amino acids
    • Kapetanovic IM, Yonekawa WD, Kupferberg HJ. 1993. Time-related loss of glutamine from hippocampal slices and concomitant changes in neurotransmitter amino acids. J Neurochem 61:865-872.
    • (1993) J Neurochem , vol.61 , pp. 865-872
    • Kapetanovic, I.M.1    Yonekawa, W.D.2    Kupferberg, H.J.3
  • 13
    • 33744900653 scopus 로고    scopus 로고
    • Neuron-derived D-serine release provides a novel means to activate N-methyl-D-aspartate receptors
    • DOI 10.1074/jbc.M512927200
    • Kartvelishvily E, Shleper M, Balan L, Dumin E, Wolosker H. 2006. Neuron-derived D-serine release provides a novel means to activate N-methyl- D-aspartate receptors. J Biol Chem 281:14151-14162. (Pubitemid 43848343)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.20 , pp. 14151-14162
    • Kartvelishvily, E.1    Shleper, M.2    Balan, L.3    Dumin, E.4    Wolosker, H.5
  • 14
    • 6344276678 scopus 로고    scopus 로고
    • Endogenous D-serine is involved in induction of neuronal death by N-methyl-D-aspartate and simulated ischemia in rat cerebrocortical slices
    • DOI 10.1124/jpet.104.070912
    • Katsuki H, Nonaka M, Shirakawa H, Kume T, Akaike A. 2004. Endogenous D-serine is involved in induction of neuronal death by N-methyl- D-aspartate and simulated ischemia in rat cerebrocortical slices. J Pharmacol Exp Ther 311:836-844. (Pubitemid 39391574)
    • (2004) Journal of Pharmacology and Experimental Therapeutics , vol.311 , Issue.2 , pp. 836-844
    • Katsuki, H.1    Nonaka, M.2    Shirakawa, H.3    Kume, T.4    Akaike, A.5
  • 15
    • 0033780693 scopus 로고    scopus 로고
    • Delayed neuronal death
    • Kirino T. 2000. Delayed neuronal death. Neuropathology 20(Suppl): S95-S97.
    • (2000) Neuropathology , vol.20 , Issue.SUPPL.
    • Kirino, T.1
  • 16
    • 33846200381 scopus 로고    scopus 로고
    • Enantioseparation and stacking of cyanobenz[f]isoindole-amino acids by reverse polarity capillary electrophoresis and sulfated beta-cyclodextrin
    • DOI 10.1021/ac061725+
    • Kirschner DL, Jaramillo M, Green TK. 2007. Enantioseparation and stacking of Cyanobenz[f]isoindole-amino acids by reverse polarity capillary electrophoresis and sulfated beta-cyclodextrin. Anal Chem 79:736-743. (Pubitemid 46106143)
    • (2007) Analytical Chemistry , vol.79 , Issue.2 , pp. 736-743
    • Kirschner, D.L.1    Jaramillo, M.2    Green, T.K.3
  • 17
    • 0023754192 scopus 로고
    • Requirement for glycine in activation of NMDA-receptors expressed in Xenopus oocytes
    • Kleckner NW, Dingledine R. 1988. Requirement for glycine in activation of NMDA-receptors expressed in Xenopus oocytes. Science 241:835-837. (Pubitemid 18222638)
    • (1988) Science , vol.241 , Issue.4867 , pp. 835-837
    • Kleckner, N.W.1    Dingledine, R.2
  • 18
    • 36448994437 scopus 로고    scopus 로고
    • 4-Fluoro-7-nitro-2,1,3-benzoxadiazole as a fluorogenic labeling reagent for the in vivo analysis of amino acid neurotransmitters using online microdialysis-capillary electrophoresis
    • Klinker CC, Bowser MT. 2007. 4-Fluoro-7-nitro-2,1,3-benzoxadiazole as a fluorogenic labeling reagent for the in vivo analysis of amino acid neurotransmitters using online microdialysis-capillary electrophoresis. Anal Chem 79:8747-8754.
    • (2007) Anal Chem , vol.79 , pp. 8747-8754
    • Klinker, C.C.1    Bowser, M.T.2
  • 19
    • 0032845121 scopus 로고    scopus 로고
    • Ischemic cell death in brain neurons
    • Lipton P. 1999. Ischemic cell death in brain neurons. Physiol Rev 79:1431-1568. (Pubitemid 29473320)
    • (1999) Physiological Reviews , vol.79 , Issue.4 , pp. 1431-1568
    • Lipton, P.1
  • 21
    • 33845219369 scopus 로고    scopus 로고
    • Immunocytochemical visualization of d-glutamate in the rat brain
    • DOI 10.1016/j.neuroscience.2006.09.045, PII S030645220601308X
    • Mangas A, Covenas R, Bodet D, Geffard M, Aguilar LA, Yajeya J. 2007. Immunocytochemical visualization of D-glutamate in the rat brain. Neuroscience 144:654-664. (Pubitemid 44855309)
    • (2007) Neuroscience , vol.144 , Issue.2 , pp. 654-664
    • Mangas, A.1    Covenas, R.2    Bodet, D.3    Geffard, M.4    Aguilar, L.A.5    Yajeya, J.6
  • 22
    • 0042626560 scopus 로고    scopus 로고
    • Functional changes of glial glutamate transporter GLT-1 during ischemia: An in vivo study in the hippocampal CA1 of normal mice and mutant mice lacking GLT-1
    • Mitani A, Tanaka K. 2003. Functional changes of glial glutamate transporter GLT-1 during ischemia: an in vivo study in the hippocampal CA1 of normal mice and mutant mice lacking GLT-1. J Neurosci 23:7176-7182. (Pubitemid 36975882)
    • (2003) Journal of Neuroscience , vol.23 , Issue.18 , pp. 7176-7182
    • Mitani, A.1    Tanaka, K.2
  • 23
    • 58149217059 scopus 로고    scopus 로고
    • Post-cardiac arrest syndrome. Epidemiology, pathophysiology, treatment, and prognostication. A Consensus Statement from the International Liaison Committee on Resuscitation (American Heart Association, Australian and New Zealand Council on Resuscitation, European Resuscitation Council, Heart and Stroke Foundation of Canada, InterAmerican Heart Foundation
    • the American Heart Association Emergency Cardiovascular Care Committee; the Council on Cardiovascular Surgery and Anesthesia; the Council on Cardiopulmonary, Perioperative, and Critical Care; the Council on Clinical Cardiology; and the Stroke Council
    • Neumar RW, Nolan JP, Adrie C, Aibiki M, Berg RA, Bottiger BW, Callaway C, Clark RS, Geocadin RG, Jauch EC, Kern KB, Laurent I, Longstreth WT Jr, Merchant RM, Morley P, Morrison LJ, Nadkarni V, Peberdy MA, Rivers EP, Rodriguez-Nunez A, Sellke FW, Spaulding C, Sunde K, Vanden Hoek T. 2008. Post-cardiac arrest syndrome. Epidemiology, pathophysiology, treatment, and prognostication. A Consensus Statement From the International Liaison Committee on Resuscitation (American Heart Association, Australian and New Zealand Council on Resuscitation, European Resuscitation Council, Heart and Stroke Foundation of Canada, InterAmerican Heart Foundation, Resuscitation Council of Asia, and the Resuscitation Council of Southern Africa); the American Heart Association Emergency Cardiovascular Care Committee; the Council on Cardiovascular Surgery and Anesthesia; the Council on Cardiopulmonary, Perioperative, and Critical Care; the Council on Clinical Cardiology; and the Stroke Council. Circulation (in press).
    • (2008) Circulation
    • Neumar, R.W.1    Nolan, J.P.2    Adrie, C.3    Aibiki, M.4    Berg, R.A.5    Bottiger, B.W.6    Callaway, C.7    Clark, R.S.8    Geocadin, R.G.9    Jauch, E.C.10    Kern, K.B.11    Laurent, I.12    Longstreth Jr., W.T.13    Merchant, R.M.14    Morley, P.15    Morrison, L.J.16    Nadkarni, V.17    Peberdy, M.A.18    Rivers, E.P.19    Rodriguez-Nunez, A.20    more..
  • 24
    • 33744949530 scopus 로고    scopus 로고
    • Measuring D-serine efflux from mouse cortical brain slices using online microdialysis-capillary electrophoresis
    • O'Brien KB, Bowser MT. 2006. Measuring D-serine efflux from mouse cortical brain slices using online microdialysis-capillary electrophoresis. Electrophoresis 27:1949-1956.
    • (2006) Electrophoresis , vol.27 , pp. 1949-1956
    • O'Brien, K.B.1    Bowser, M.T.2
  • 25
    • 4444378876 scopus 로고    scopus 로고
    • Monitoring neurotransmitter release from isolated retinas using online microdialysis-capillary electrophoresis
    • DOI 10.1021/ac049822v
    • O'Brien KB, Esguerra M, Miller RF, Bowser MT. 2004. Monitoring neurotransmitter release from isolated retinas using online microdialysiscapillary electrophoresis. Anal Chem 76:5069-5074. (Pubitemid 39180335)
    • (2004) Analytical Chemistry , vol.76 , Issue.17 , pp. 5069-5074
    • O'Brien, K.B.1    Esguerra, M.2    Miller, R.F.3    Bowser, M.T.4
  • 26
    • 0034698252 scopus 로고    scopus 로고
    • Blocking the glycine-binding site of NMDA receptors prevents the progression of ischemic pathology induced by bilateral carotid artery occlusion in spontaneously hypertensive rats
    • DOI 10.1016/S0006-8993(00)02486-0, PII S0006899300024860
    • Ohtani K, Tanaka H, Yasuda H, Maruoka Y, Kawabe A, Nakamura M. 2000. Blocking the glycine-binding site of NMDA receptors prevents the progression of ischemic pathology induced by bilateral carotid artery occlusion in spontaneously hypertensive rats. Brain Res 871:311-318. (Pubitemid 30433882)
    • (2000) Brain Research , vol.871 , Issue.2 , pp. 311-318
    • Ohtani, K.-I.1    Tanaka, H.2    Yasuda, H.3    Maruoka, Y.4    Kawabe, A.5    Nakamura, M.6
  • 27
    • 0037375749 scopus 로고    scopus 로고
    • SM-31900, a novel NMDA receptor glycine-binding site antagonist, reduces infarct volume induced by permanent middle cerebral artery occlusion in spontaneously hypertensive rats
    • DOI 10.1016/S0197-0186(02)00137-7, PII S0197018602001377
    • Ohtani K, Tanaka H, Ohno Y. 2003. SM-31900, a novel NMDA receptor glycine-binding site antagonist, reduces infarct volume induced by permanent middle cerebral artery occlusion in spontaneously hypertensive rats. Neurochem Int 42:375-384. (Pubitemid 36044670)
    • (2003) Neurochemistry International , vol.42 , Issue.5 , pp. 375-384
    • Ohtani, K.-I.1    Tanaka, H.2    Ohno, Y.3
  • 28
    • 33750326614 scopus 로고    scopus 로고
    • Molecular determinants of D-serine-mediated gliotransmission: From release to function
    • Oliet SH, Mothet JP. 2006. Molecular determinants of D-serine-mediated gliotransmission: from release to function. Glia 54:726-737.
    • (2006) Glia , vol.54 , pp. 726-737
    • Oliet, S.H.1    Mothet, J.P.2
  • 29
    • 0035167923 scopus 로고    scopus 로고
    • Studies on the effects of lactate transport inhibition, pyruvate, glucose and glutamine on amino acid, lactate and glucose release from the ischemic rat cerebral cortex
    • DOI 10.1046/j.1471-4159.2001.00050.x
    • Phillis JW, Ren J, O'Regan MH. 2001. Studies on the effects of lactate transport inhibition, pyruvate, glucose and glutamine on amino acid, lactate and glucose release from the ischemic rat cerebral cortex. J Neurochem 76:247-257. (Pubitemid 32044387)
    • (2001) Journal of Neurochemistry , vol.76 , Issue.1 , pp. 247-257
    • Phillis, J.W.1    Ren, J.2    O'Regan, M.H.3
  • 30
    • 0347135590 scopus 로고    scopus 로고
    • Capillary electrophoretic separation of glutamate enantiomers in neural samples
    • DOI 10.1002/elps.200390127
    • Quan Z, Liu YM. 2003. Capillary electrophoretic separation of glutamate enantiomers in neural samples. Electrophoresis 24:1092-1096. (Pubitemid 38088884)
    • (2003) Electrophoresis , vol.24 , Issue.6 , pp. 1092-1096
    • Quan, Z.1    Liu, Y.-M.2
  • 32
    • 33644849222 scopus 로고    scopus 로고
    • Heart disease and stroke statistics - 2006 Update: A report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee
    • DOI 10.1161/CIRCULATIONAHA.105.171600, PII 0000301720060214000028
    • Rosamond W, Flegal K, Furie K, Go A, Greenlund K, Haase N, Hailpern SM, Ho M, Howard V, Kissela B, Kittner S, Lloyd-Jones D, McDermott M, Meigs J, Moy C, Nichol G, O'Donnell C, Roger V, Sorlie P, Steinberger J, Thom T, Wilson M, Hong Y. 2008. Heart disease and stroke statistics - 2008 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation 117:e25-e146. (Pubitemid 43754289)
    • (2006) Circulation , vol.113 , Issue.6
    • Thom, T.1    Haase, N.2    Rosamond, W.3    Howard, V.J.4    Rumsfeld, J.5    Manolio, T.6    Zheng, Z.-J.7    Flegal, K.8    O'Donnell, C.9    Kittner, S.10    Lloyd-Jones, D.11    Goff Jr., D.C.12    Hong, Y.13
  • 33
    • 34047261852 scopus 로고    scopus 로고
    • Evidence from gene knockout studies implicates Asc-1 as the primary transporter mediating D-serine reuptake in the mouse CNS
    • DOI 10.1111/j.1460-9568.2007.05446.x
    • Rutter AR, Fradley RL, Garrett EM, Chapman KL, Lawrence JM, Rosahl TW, Patel S. 2007. Evidence from gene knockout studies implicates Asc-1 as the primary transporter mediating d-serine reuptake in the mouse CNS. Eur J Neurosci 25:1757-1766. (Pubitemid 46550015)
    • (2007) European Journal of Neuroscience , vol.25 , Issue.6 , pp. 1757-1766
    • Rutter, A.R.1    Fradley, R.L.2    Garrett, E.M.3    Chapman, K.L.4    Lawrence, J.M.5    Rosahl, T.W.6    Patel, S.7
  • 34
    • 0025881551 scopus 로고
    • Selective vulnerability of the hippocampus in brain ischemia
    • Schmidt-Kastner R, Freund TF. 1991. Selective vulnerability of the hippocampus in brain ischemia. Neuroscience 40:599-636.
    • (1991) Neuroscience , vol.40 , pp. 599-636
    • Schmidt-Kastner, R.1    Freund, T.F.2
  • 35
    • 58149173385 scopus 로고    scopus 로고
    • Determination of the glutamate- Glutamine cycling flux using two-compartment dynamic metabolic modeling is sensitive to astroglial dilution
    • in press
    • Shen J, Rothman DL, Behar KL, Xu S. 2008. Determination of the glutamate- glutamine cycling flux using two-compartment dynamic metabolic modeling is sensitive to astroglial dilution. J Cereb Blood Flow Metab (in press).
    • (2008) J Cereb Blood Flow Metab
    • Shen, J.1    Rothman, D.L.2    Behar, K.L.3    Xu, S.4
  • 36
    • 26844461474 scopus 로고    scopus 로고
    • D-serine is the dominant endogenous coagonist for NMDA receptor neurotoxicity in organotypic hippocampal slices
    • DOI 10.1523/JNEUROSCI.3190-05.2005
    • Shleper M, Kartvelishvily E, Wolosker H. 2005. D-serine is the dominant endogenous coagonist for NMDA receptor neurotoxicity in organotypic hippocampal slices. J Neurosci 25:9413-9417. (Pubitemid 41464754)
    • (2005) Journal of Neuroscience , vol.25 , Issue.41 , pp. 9413-9417
    • Shleper, M.1    Kartvelishvily, E.2    Wolosker, H.3
  • 37
    • 0026345956 scopus 로고
    • Hypoxia-ischemia stimulates hippocampal glutamate efflux in perinatal rat brain: An in vivo microdialysis study
    • Silverstein FS, Naik B, Simpson J. 1991. Hypoxia-ischemia stimulates hippocampal glutamate efflux in perinatal rat brain: an in vivo microdialysis study. Pediatric Res 30:587-590.
    • (1991) Pediatric Res , vol.30 , pp. 587-590
    • Silverstein, F.S.1    Naik, B.2    Simpson, J.3
  • 38
    • 0027953005 scopus 로고
    • Changes in the extracellular concentrations of amino acids in the rat striatum during transient focal cerebral ischemia
    • Uchiyama-Tsuyuki Y, Araki H, Yae T, Otomo S. 1994. Changes in the extracellular concentrations of amino acids in the rat striatum during transient focal cerebral ischemia. J Neurochem 62:1074-1078. (Pubitemid 24064521)
    • (1994) Journal of Neurochemistry , vol.62 , Issue.3 , pp. 1074-1078
    • Uchiyama-Tsuyuki, Y.1    Araki, H.2    Yae, T.3    Otomo, S.4
  • 39
    • 17444377551 scopus 로고    scopus 로고
    • Determination of amino acids associated with cerebral ischaemia in rat brain microdialysates using narrowbore liquid chromatography and fluorescence detection
    • DOI 10.1016/j.jneumeth.2004.10.013
    • Van Hemelrijck A, Sarre S, Smolders I, Michotte Y. 2005. Determination of amino acids associated with cerebral ischaemia in rat brain microdialysates using narrowbore liquid chromatography and fluorescence detection. J Neurosci Methods 144:63-71. (Pubitemid 40546303)
    • (2005) Journal of Neuroscience Methods , vol.144 , Issue.1 , pp. 63-71
    • Van Hemelrijck, A.1    Sarre, S.2    Smolders, I.3    Michotte, Y.4
  • 40
    • 0030002689 scopus 로고    scopus 로고
    • Felbamate protects CA1 neurons from apoptosis in a gerbil model of global ischemia
    • Wasterlain CG, Adams LM, Wichmann JK, Sofia RD. 1996. Felbamate protects CA1 neurons from apoptosis in a gerbil model of global ischemia. Stroke 27:1236-1240. (Pubitemid 26226962)
    • (1996) Stroke , vol.27 , Issue.7 , pp. 1236-1240
    • Wasterlain, C.G.1    Adams, L.M.2    Wichmann, J.K.3    Sofia, R.D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.