Determination of the glutamate-glutamine cycling flux using two-compartment dynamic metabolic modeling is sensitive to astroglial dilution

Journal of Cerebral Blood Flow and Metabolism

Volumn 29, Issue 1, 2009, Pages 108-118

  Shen, Jun ^a   Rothman, Douglas L ^b   Behar, Kevin L ^b   Xu, Su ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

13C isotopes; Brain glucose metabolism; Glutamate glutamine neurotransmitter cycling; Magnetic resonance spectroscopy

Indexed keywords

GLUTAMIC ACID; GLUTAMINE;

AMINO ACID METABOLISM; ARTICLE; COMPARTMENT MODEL; DILUTION; GLUCOSE INFUSION; MACROGLIA; MONTE CARLO METHOD; NERVE CELL; PRIORITY JOURNAL;

ASTROCYTES; GLUTAMIC ACID; GLUTAMINE; HUMANS; MODELS, BIOLOGICAL; MONTE CARLO METHOD; SUBSTRATE SPECIFICITY;

EID: 58149173385     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1038/jcbfm.2008.102     Document Type: Article

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