Inherent differences in morphology, proliferation, and migration in saphenous vein smooth muscle cells cultured from nondiabetic and Type 2 diabetic patients

American Journal of Physiology - Cell Physiology

Volumn 297, Issue 5, 2009, Pages

  Madi, Haifa A ^a   Riches, Kirsten ^a,b   Warburton, Philip ^a,b   O'Regan, David J ^b,c   Turner, Neil A ^a,b   Porter, Karen E ^a,b  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b UNIVERSITY OF LEEDS   (United Kingdom)

^c LEEDS GENERAL INFIRMARY   (United Kingdom)

Author keywords

Diabetes mellitus; Metabolic memory; Vein graft stenosis

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CALVASCULIN; F ACTIN; GLUCOSE; GLYCOGEN SYNTHASE KINASE 3BETA; INSULIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PLATELET DERIVED GROWTH FACTOR; PROTEIN KINASE B; SERINE; THREONINE;

ADULT; AGED; ARTICLE; CELL COUNT; CELL MIGRATION; CELL POPULATION; CELL PROLIFERATION; CELL SHAPE; CELL STRUCTURE; CLINICAL ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSKELETON; DIABETIC PATIENT; FEMALE; FETAL CALF SERUM; FOCAL ADHESION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; MALE; MICROSCOPY; NON INSULIN DEPENDENT DIABETES MELLITUS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; SAPHENOUS VEIN; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

ADULT; AGED; BLOTTING, WESTERN; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; DIABETES MELLITUS, TYPE 2; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PROTO-ONCOGENE PROTEINS C-AKT; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; S100 PROTEINS; SAPHENOUS VEIN; SIGNAL TRANSDUCTION;

EID: 70449632887     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00608.2008     Document Type: Article

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