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Volumn 39, Issue 11, 2009, Pages 2969-2972

Why Aire? Compensating for late bloomers

Author keywords

Aire regulation; Autoimmunity; Negative selection; T cell tolerance; Transcription factor

Indexed keywords

ANTIGEN; AUTOIMMUNE REGULATOR PROTEIN;

EID: 70449564748     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.200939628     Document Type: Note
Times cited : (15)

References (29)
  • 2
    • 60749084080 scopus 로고    scopus 로고
    • On the opposing views of the self-nonself discrimination by the immune system
    • Cohn, M., On the opposing views of the self-nonself discrimination by the immune system. Immunology and Cell Biology 2009. 87: 113-119.
    • (2009) Immunology and Cell Biology , vol.87 , pp. 113-119
    • Cohn, M.1
  • 3
    • 36248951719 scopus 로고    scopus 로고
    • Conceptualizing the Self-Nonself discrimination by the vertebrate immune system
    • Timmis, J., Flower, D. (Eds.) Springer, New York
    • Cohn, M., Conceptualizing the Self-Nonself discrimination by the vertebrate immune system. In Timmis, J., Flower, D. (Eds.) In Silico Immunology. Springer, New York 2007, pp 375-398.
    • (2007) In Silico Immunology , pp. 375-398
    • Cohn, M.1
  • 4
    • 21344459077 scopus 로고    scopus 로고
    • The common sense of the Self-Nonself discrimination
    • Cohn, M., The common sense of the Self-Nonself discrimination. Springer Seminars in Immunopathology 2005. 27: 3-17.
    • (2005) Springer Seminars in Immunopathology , vol.27 , pp. 3-17
    • Cohn, M.1
  • 5
    • 18244394284 scopus 로고    scopus 로고
    • A biological context for the self-nonself discrimination and the regulation of effector class by the immune system
    • DOI 10.1385/IR:31:2:133
    • Cohn, M., A biological context for the Self-Nonself discrimination and the regulation of effector class by the immune system. Immunol Res. 2005. 31: 133-150. (Pubitemid 40631384)
    • (2005) Immunologic Research , vol.31 , Issue.2 , pp. 133-150
    • Cohn, M.1
  • 6
    • 0037406492 scopus 로고    scopus 로고
    • A computerized model for the self-nonself discrimination at the level of the T-helper (Th genesis) II. The behavior of the system upon encounter with nonself antigens
    • Langman, R. E., Mata, J. J. and Cohn, M., A computerized model for the self-nonself discrimination at the level of the T-helper (Th genesis) II. The behavior of the system upon encounter with nonself antigens. Int Immun. 2003. 15: 593-609.
    • (2003) Int Immun , vol.15 , pp. 593-609
    • Langman, R.E.1    Mata, J.J.2    Cohn, M.3
  • 7
    • 0036796380 scopus 로고    scopus 로고
    • A computerized model for the self-nonself discrimination at the level of the T-helper (Th-genesis). I. The origin of "primer" effector T-helpers
    • Cohn, M., Langman, R. E. and Mata, J., A computerized model for the self-nonself discrimination at the level of the T-helper (Th-genesis). I. The origin of "primer" effector T-helpers. Int'l. Immunol. 2002. 14: 1105-1112.
    • (2002) Int'l. Immunol. , vol.14 , pp. 1105-1112
    • Cohn, M.1    Langman, R.E.2    Mata, J.3
  • 8
    • 0023108381 scopus 로고
    • Non-tolerance and autoantibodies to a transgenic self antigen expressed in pancreatic B cells
    • Adams, T. E., Alpert, S. and Hanahan, D., Non-tolerance and autoantibodies to a transgenic self antigen expressed in pancreatic B cells. Nature 1987. 325: 223-228.
    • (1987) Nature , vol.325 , pp. 223-228
    • Adams, T.E.1    Alpert, S.2    Hanahan, D.3
  • 9
    • 0027340334 scopus 로고
    • The role of thymic epithelium in the establishment of transplantation tolerance
    • Coutinho, A., Salaun, J., Corbel, C., Bandeira, A. and Le Douarin, N., The role of thymic epithelium in the establishment of transplantation tolerance. Immunol Rev. 1993. 133: 225-240. (Pubitemid 23302399)
    • (1993) Immunological Reviews , Issue.133 , pp. 225-240
    • Coutinho, A.1    Salaun, J.2    Corbel, C.3    Bandeira, A.4    Le Douarin, N.5
  • 10
    • 0023239988 scopus 로고
    • Tolerance induced by thymic epithelial grafts in birds
    • Ohki, H., Martin, C., Corbel, C., Coltey, and Le Douarin, N., Tolerance induced by thymic epithelial grafts in birds. Science 1987. 237: 1032-1035. (Pubitemid 17124674)
    • (1987) Science , vol.237 , Issue.4818 , pp. 1032-1035
    • Ohki, H.1    Martin, C.2    Corbel, C.3
  • 15
    • 45949094459 scopus 로고    scopus 로고
    • The Lymphotoxin Pathway Regulates Aire-Independent Expression of Ectopic Genes and chemokines in Thymic Stromal Cells
    • Seach, N., Ueno, T., Fletcher, A. L., Lowen, T., Mattesich, M., Engwerda, C. R., Scott, H. S. et al., The Lymphotoxin Pathway Regulates Aire-Independent Expression of Ectopic Genes and chemokines in Thymic Stromal Cells. Journal of Immunology 2008. 180: 5384-5392.
    • (2008) Journal of Immunology , vol.180 , pp. 5384-5392
    • Seach, N.1    Ueno, T.2    Fletcher, A.L.3    Lowen, T.4    Mattesich, M.5    Engwerda, C.R.6    Scott, H.S.7
  • 16
    • 44849090702 scopus 로고    scopus 로고
    • Sequential phases in the development of Aire-expressing medullary thymic epithelial cells involve distinct cellular input
    • White, A. J., Withers, D. R., Parnell, S., Scott, H. S., Finke, D., Lane, P. J. L., Jenkinson, E. J. and Anderson, G., Sequential phases in the development of Aire-expressing medullary thymic epithelial cells involve distinct cellular input. Eur J Immunol 2008. 38: 942-947.
    • (2008) Eur J Immunol , vol.38 , pp. 942-947
    • White, A.J.1    Withers, D.R.2    Parnell, S.3    Scott, H.S.4    Finke, D.5    Lane, P.J.L.6    Jenkinson, E.J.7    Anderson, G.8
  • 18
    • 44849114330 scopus 로고    scopus 로고
    • A Specific Anti-Aire Antibody Reveals Aire Expression is Restricted to Medullary Thymic Epithelial Cells and Not Expressed in Periphery
    • Hubert, F.-X., Kinkel, S. A., Webster, K. E., Cannon, P., Crewther, P. E., Proeitto, A. I., Wu, L. et al., A Specific Anti-Aire Antibody Reveals Aire Expression is Restricted to Medullary Thymic Epithelial Cells and Not Expressed in Periphery. Journal of Immunology 2008. 180: 3824-3832.
    • (2008) Journal of Immunology , vol.180 , pp. 3824-3832
    • Hubert, F.-X.1    Kinkel, S.A.2    Webster, K.E.3    Cannon, P.4    Crewther, P.E.5    Proeitto, A.I.6    Wu, L.7
  • 19
    • 4544258485 scopus 로고    scopus 로고
    • Self-Representation in the Thymus: An Extended View
    • Kyewski, B. and Derbinski, J., Self-Representation in the Thymus: An Extended View. Nature Reviews Immunology 2004. 4: 688-698.
    • (2004) Nature Reviews Immunology , vol.4 , pp. 688-698
    • Kyewski, B.1    Derbinski, J.2
  • 20
    • 0942288397 scopus 로고    scopus 로고
    • Medullary Epithelial Cells of the Human Thymus Express a Highly Diverse Selection of Tissue-specific Genes Colocalized in Chromosomal Clusters
    • DOI 10.1084/jem.20031677
    • Gotter, J., Brors, B., Hergenhahn, M. and Kyewski, B., Medullary Epithelial Cells of the Human Thymus Express a Highly Diverse Selextion of Tissue-specific Genes Colocalized in Chromosomal Clusters. Journal of Experimental Medicine 2004. 199: 155-166. (Pubitemid 38139246)
    • (2004) Journal of Experimental Medicine , vol.199 , Issue.2 , pp. 155-166
    • Gotter, J.1    Brors, B.2    Hergenhahn, M.3    Kyewski, B.4
  • 21
    • 33646165128 scopus 로고    scopus 로고
    • A Central Role for Central Tolerance
    • Kyewski, B. and Klein, L., A Central Role for Central Tolerance. Ann. Rev. Immunol. 2006. 24: 571-606.
    • (2006) Ann. Rev. Immunol. , vol.24 , pp. 571-606
    • Kyewski, B.1    Klein, L.2
  • 22
    • 67549104034 scopus 로고    scopus 로고
    • Neonatal tolerance revisited: A perinatal window for Aire control of autoimmunity
    • Guerau-de-Arellano, M., Martinic, M., Benoist, C. and Mathis, D., Neonatal tolerance revisited: a perinatal window for Aire control of autoimmunity. JEM 2009. 206: 1245-1252.
    • (2009) JEM , vol.206 , pp. 1245-1252
    • Guerau-de-Arellano, M.1    Martinic, M.2    Benoist, C.3    Mathis, D.4
  • 23
    • 0242491713 scopus 로고
    • Antibody diversity 1983: Some elementary considerations
    • Yamamura, Y., Tada, T. (Eds.) Academic Press, Orlando, Florida
    • Cohn, M., Antibody diversity 1983: Some elementary considerations. In Yamamura, Y., Tada, T. (Eds.) Progress in Immunology V. Academic Press, Orlando, Florida 1983, pp 839-851.
    • (1983) Progress in Immunology V , pp. 839-851
    • Cohn, M.1
  • 25
    • 0026690960 scopus 로고
    • The self-nonself discrimination: Reconstructing a cabbage from sauerkraut
    • Cohn, M., The self-nonself discrimination: Reconstructing a cabbage from sauerkraut. Res. Immunol. 1992. 143: 323-334.
    • (1992) Res. Immunol. , vol.143 , pp. 323-334
    • Cohn, M.1
  • 26
    • 57249095654 scopus 로고    scopus 로고
    • How does the immune response get started?
    • Cohn, M., How does the immune response get started? Cell. Immunol. 2009. 254: 91-93.
    • (2009) Cell. Immunol. , vol.254 , pp. 91-93
    • Cohn, M.1
  • 28
    • 33749524196 scopus 로고    scopus 로고
    • Aire deficient mice do not develop the same profile of tissue-specific autoantibodies as APECED patients
    • DOI 10.1016/j.jaut.2006.06.001, PII S089684110600045X
    • Pontynen, N., Miettinen, A., Arstila, T. P., Kampe, O., Alimohammadi, M., Vaarala, O., Peltonen, L. and Ulmanen, I., Aire deficient mice do not develop the same profile of tissue-specific autoantibodies as APECED patients. Journal of Autoimmunity 2006. 27: 96-104. (Pubitemid 44528258)
    • (2006) Journal of Autoimmunity , vol.27 , Issue.2 , pp. 96-104
    • Pontynen, N.1    Miettinen, A.2    Petteri Arstila, T.3    Kampe, O.4    Alimohammadi, M.5    Vaarala, O.6    Peltonen, L.7    Ulmanen, I.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.