Osteopontin expression in osteoblasts and osteocytes during bone formation under mechanical stress in the calvarial suture in vivo

Journal of Bone and Mineral Research

Volumn 18, Issue 9, 2003, Pages 1706-1715

  Morinobu, Mikihiko ^a   Ishijima, Muneaki ^a   Rittling, Susan R ^b   Tsuji, Kunikazu ^a   Yamamoto, Haruyasu ^c   Nifuji, Akira ^a   Denhardt, David T ^b   Noda, Masaki ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b RUTGERS UNIVERSITY   (United States)

^c EHIME UNIVERSITY   (Japan)

Author keywords

Distraction osteogenesis; Intramembranous ossification; Mechanical stress; Osteoblasts; Osteopontin

Indexed keywords

COLLAGEN TYPE 1; MESSENGER RNA; OSTEOPONTIN; SCLEROPROTEIN;

ANIMAL TISSUE; ARTICLE; CALVARIA; CONTROLLED STUDY; DISTRACTION OSTEOGENESIS; IMMUNOHISTOCHEMISTRY; MECHANICAL STRESS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OSSIFICATION; OSTEOBLAST; OSTEOCYTE; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SKULL SUTURE;

ANIMALS; BASE SEQUENCE; CRANIAL SUTURES; DNA, COMPLEMENTARY; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MICE; MICE, KNOCKOUT; OSTEOBLASTS; OSTEOCYTES; OSTEOGENESIS; OSTEOPONTIN; RNA, MESSENGER; SIALOGLYCOPROTEINS; STRESS, MECHANICAL;

EID: 0042978654     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.2003.18.9.1706     Document Type: Article

References (30)

1. Ishijima M, Rittling SR, Yamashita T, Tsuji K, Kurosawa H, Nifuji A, Denhardt DT, Noda M 2001 Enhancement of osteoclastic bone resorption and suppression of osteoblastic bone formation in response to reduced mechanical stress do not occur in the absence of osteopontin. J Exp Med 193:399-404.
2. Meghji S 1992 Bone remodelling. Br Dent J 172:235-242.
3. Carter DR, Beaupre GS, Giori NJ, Helms JA 1998 Mechanobiology of skeletal regeneration. Clin Orthop 355(Suppl):S41-S55.
4. Hill PA 1998 Bone remodelling. Br J Orthod 25:101-107.
5. Bikle DD, Halloran BP 1999 The response of bone to unloading. J Bone Miner Metab 17:233-244.
6. Singh R, Umemura Y, Honda A, Nagasawa S 2002 Maintenance of bone mass and mechanical properties after short-term cessation of high impact exercise in rats. Int J Sports Med 23:77-81.
7. Xie LQ, Liu CL 1999 Developments of the theory of skeletal adaptation to mechanical loading. Space Med Med Eng (Beijing) 12:226-230.
8. Takata S, Yasui N 2001 Disuse osteoporosis. J Med Invest 48:147-156.
9. Denhardt DT, Guo X 1993 Osteopontin: A protein with diverse functions. FASEB J 7:1475-1482.
10. Rodan GA 1995 Osteopontin overview. Ann NY Acad Sci 760:1-5.
11. Denhardt DT, Noda M 1998 Osteopontin expression and function: Role in bone remodeling. J Cell Biochem 30-31(Suppl):92-102.
12. Yamate T, Mocharla H, Taguchi Y, Igietseme JU, Manolagas SC, Abe E 1997 Osteopontin expression by osteoclast and osteoblast progenitors in the murine bone marrow: Demonstration of its requirement for osteoclastogenesis and its increase after ovariectomy. Endocrinology 138:3047-3055.
13. Ihara H, Denhardt DT, Furuya K, Yamashita T, Muguruma Y, Tsuji K, Hruska KA, Higashio K, Enomoto S, Nifuji A, Rittling SR, Noda M 2001 Parathyroid hormone-induced bone resorption does not occur in the absence of osteopontin. J Biol Chem 276:13065-13071.
14. Yoshitake H, Rittling SR, Denhardt DT, Noda M 1999 Osteopontin-deficient mice are resistant to ovariectomy-induced bone resorption. Proc Natl Acad Sci USA 96:8156-8160.
15. Kodama Y, Nakayama K, Fuse H, Fukumoto S, Kawahara H, Takahashi H, Kurokawa T, Sekiguchi C, Nakamura T, Matsumoto T 1997 Inhibition of bone resorption by pamidronate cannot restore normal gain in cortical bone mass and strength in tail-suspended rapidly growing rats. J Bone Miner Res 12:1058-1067.
16. Rittling SR, Matsumoto HN, McKee MD, Nanci A, An XR, Novick KE, Kowalski AJ, Noda M, Denhardt DT 1998 Mice lacking osteopontin show normal development and bone structure but display altered osteoclast formation in vitro. J Bone Miner Res 13:1101-1111.
17. You J, Reilly GC, Zhen X, Yellowley CE, Chen Q, Donahue HJ, Jacobs CR 2001 Osteopontin gene regulation by oscillatory fluid flow via intracellular calcium mobilization and activation of mitogen-activated protein kinase in MC3T3-E1 osteoblasts. J Biol Chem 276:13365-13371.
18. Toma CD, Ashkar S, Gray ML, Schaffer JL, Gerstenfeld LC 1997 Signal transduction of mechanical stimuli is dependent on microfilament integrity: Identification of osteopontin as a mechanically induced gene in osteoblasts. J Bone Miner Res 12:1626-1636.
19. Harter LV, Hruska KA, Duncan RL 1995 Human osteoblast-like cells respond to mechanical strain with increased bone matrix protein production independent of hormonal regulation. Endocrinology 136:528-535.
20. Walker LM, Publicover SJ, Preston MR, Said Ahmed MA, El Haj AJ 2000 Calcium-channel activation and matrix protein upregulation in bone cells in response to mechanical strain. J Cell Biochem 79:648-661.
21. Terai K, Takano-Yamamoto T, Ohba Y, Hiura K, Sugimoto M, Sato M, Kawahata H, Inaguma N, Kitamura Y, Nomura S 1999 Role of osteopontin in bone remodeling caused by mechanical stress. J Bone Miner Res 14:839-849.
22. Perrien DS, Brown EC, Aronson J, Skinner RA, Montague DC, Badger TM, Lumpkin CK Jr 2002 Immunohistochemical study of osteopontin expression during distraction osteogenesis in the rat. J Histochem Cytochem 50:567-574.
23. Sato M, Yasui N, Nakase T, Kawahata H, Sugimoto M, Hirota S, Kitamura Y, Nomura S, Ochi T 1998 Expression of bone matrix proteins mRNA during distraction osteogenesis. J Bone Miner Res 13:1221-1231.
24. Ishijima M, Tsuji K, Rittling SR, Yamashita T, Kurosawa H, Denhardt DT, Nifuji A, Noda M 2002 Resistance to unloading-induced three-dimensional bone loss in osteopontin-deficient mice. J Bone Miner Res 17:661-667.
25. Ross FP, Chappel J, Alvarez JI, Sander D, Butler WT, Farach-Carson MC, Mintz KA, Robey PG, Teitelbaum SL, Cheresh DA 1993 Interactions between the bone matrix proteins osteopontin and bone sialoprotein and the osteoclast integrin alpha v beta 3 potentiate bone resorption. J Biol Chem 268:9901-9907.
26. Wozniak M, Fausto A, Carron CP, Meyer DM, Hruska KA. 2000 Mechanically strained cells of the osteoblast lineage organize their extracellular matrix through unique sites of alphavbeta3-integrin expression. J Bone Miner Res 15:1731-1745.
27. Sato M, Yasui N, Nakase T, Kawahata H, Sugimoto M, Hirota S, Kitamura Y, Nomura S, Ochi T 1998 Expression of bone matrix proteins mRNA during distraction osteogenesis. J Bone Miner Res 13:1221-1231.
28. Aldegheri R 1999 Distraction osteogenesis for lengthening of the tibia in patients who have limb-length discrepancy or short stature. J Bone Joint Surg Am 81:624-634.
29. Yasui N, Sato M, Ochi T, Kimura T, Kawahata H, Kitamura Y, Nomura S 1997 Three modes of ossification during distraction osteogenesis in the rat. J Bone Joint Surg Br 79:824-830.
30. Ikegame M, Ishibashi O, Yoshizawa T, Shimomura J, Komori T, Ozawa H, Kawashima H 2001 Tensile stress induces bone morphogenetic protein 4 in preosteoblastic and fibroblastic cells, which later differentiate into osteoblasts leading to osteogenesis in the mouse calvariae in organ culture. J Bone Miner Res 16:24-32.