Anti-inflammatory activity of ghrelin in human carotid artery cells

Inflammation

Volumn 32, Issue 6, 2009, Pages 402-409

  Chow, Kevin B S ^a   Cheng, Christopher H K ^a   Wise, Helen ^a  

^a and Hong Kong Branch of CAS Center for Excellence in Animal Evolution and Genetics   (Hong Kong)

Author keywords

Ghrelin; Human coronary artery; Inflammation; Prostanoid receptors

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; CYCLOOXYGENASE 2; GHRELIN; GHRELIN RECEPTOR; GHRELIN RECEPTOR 1B; MESSENGER RNA; PROSTANOID RECEPTOR; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ARTERY ENDOTHELIUM; ARTICLE; CAROTID ARTERY; CONTROLLED STUDY; CORONARY ARTERY; ENDOTHELIUM CELL; GENE EXPRESSION; HUMAN; HUMAN CELL; INFLAMMATION; NUCLEOTIDE SEQUENCE; OLIGOMERIZATION; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SMOOTH MUSCLE FIBER; VASCULITIS;

CAROTID ARTERIES; CELL LINE; CELLS, CULTURED; GHRELIN; HUMANS; INFLAMMATION MEDIATORS; MUSCLE, SMOOTH, VASCULAR; RECEPTORS, GHRELIN; RNA, MESSENGER;

EID: 70449521981     PISSN: 03603997     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10753-009-9149-8     Document Type: Article

References (36)

1. B. Holst T. W. Schwartz 2004 Constitutive ghrelin receptor activity as a signaling set-point in appetite regulation Trends Pharmacol. Sci. 25 113 117 10.1016/j.tips.2004.01.010 1:CAS:528:DC%2BD2cXhslCjt7c%3D 15058279 (Pubitemid 38264498)
2. K. E. Wiley A. P. Davenport 2002 Comparison of vasodilators in human internal mammary artery: ghrelin is a potent physiological antagonist of endothelin-1 Br. J. Pharmacol. 136 1146 1152 10.1038/sj.bjp.0704815 1:CAS:528:DC%2BD38XmslSksbg%3D 12163347 (Pubitemid 34970066)
3. T. Waseem M. Duxbury H. Ito S. W. Ashley M. K. Robinson 2008 Exogenous ghrelin modulates release of pro-inflammatory and anti-inflammatory cytokines in LPS-stimulated macrophages through distinct signaling pathways Surgery 143 334 342 10.1016/j.surg.2007.09.039 18291254
4. S. D. Katugampola R. E. Kuc J. J. Maguire A. P. Davenport 2002 G-protein-coupled receptors in human atherosclerosis: comparison of vasoconstrictors (endothelin and thromboxane) with recently de-orphanized (urotensin-II, apelin and ghrelin) receptors Clin. Sci. 103 Suppl. 48 171S 175S 1:CAS:528:DC%2BD38XotFKhurY%3D 12193079
5. M. Iantorno H. Chen J. Kim M. Tesauro D. Lauro C. Cardillo M. J. Quon 2007 Ghrelin has novel vascular actions that mimic PI 3-kinase-dependent actions of insulin to stimulate production of NO from endothelial cells Am. J. Physiol. Endocrinol. Metab. 292 E756 E764 10.1152/ajpendo.00570.2006 1:CAS:528:DC%2BD2sXjsFeqtrg%3D 17106060 (Pubitemid 46411053)
6. X. Xu B. Sook Jhun C. Hoon Ha Z. G. Jin 2008 Molecular mechanisms of ghrelin-mediated endothelial nitric oxide synthase activation Endocrinology 149 4183 4192 10.1210/en.2008-0255 1:CAS:528:DC%2BD1cXptlamtLc%3D 18450953
7. P. K. Leung K. B. S. Chow P. N. Lau K. M. Chu C. B. Chan C. H. K. Cheng H. Wise 2007 The truncated ghrelin receptor polypeptide (GHS-R1b) acts as a dominant-negative mutant of the ghrelin receptor Cell Signal 19 1011 1022 10.1016/j.cellsig.2006.11.011 1:CAS:528:DC%2BD2sXjsVSrurg%3D 17229547 (Pubitemid 46437436)
8. K. B. S. Chow P. K. Leung C. H. K. Cheng W. T. Cheung H. Wise 2008 The constitutive activity of ghrelin receptors is decreased by co-expression with vasoactive prostanoid receptors when over-expressed in human embryonic kidney 293 cells Int. J. Biochem. Cell Biol. 40 2627 2637 10.1016/j.biocel.2008.05.008 1:CAS:528:DC%2BD1cXpsVansrs%3D 18573679
9. F. Cipollone M. L. Fazia 2006 COX-2 and atherosclerosis J. Cardiovasc. Pharmacol. 47 S26 S36 10.1097/00005344-200605001-00006 1:CAS:528: DC%2BD28XlvV2nsr0%3D 16785826 (Pubitemid 44651782)
10. X. Norel 2007 Prostanoid receptors in the human vascular wall Scientific World Journal 7 1359 1374 1:CAS:528:DC%2BD2sXhtlequ77J 17767355
11. A. Gómez-Hernández J. L. Martín-Ventura E. Sánchez-Galán C. Vidal M. Ortego L. M. Blanco-Colio L. Ortega J. Tuñón J. Egido 2006 Overexpression of COX-2, prostaglandin E synthase-1 and prostaglandin E receptors in blood mononuclear cells and plaque of patients with carotid atherosclerosis: regulation by nuclear factor-κB Atherosclerosis 187 139 149 10.1016/j.atherosclerosis.2005.08.035 16212965 (Pubitemid 43817006)
12. T. Murata F. Ushikubi T. Matsuoka M. Hirata A. Yamasaki Y. Sugimoto A. Ichikawa Y. Aze T. Tanaka N. Yoshida A. Ueno S. Oh-Ishi S. Narumiya 1997 Altered pain perception and inflammatory response in mice lacking prostacyclin receptor Nature 388 678 682 10.1038/41780 1:CAS:528:DyaK2sXlsFSjt7c%3D 9262402 (Pubitemid 27366439)
13. 2 and prostacyclin in the development of atherosclerosis in apoE-deficient mice J. Clin. Invest. 114 784 794 1:CAS:528:DC%2BD2cXnslWiuro%3D 15372102
14. 2 and other constrictor agents on rat femoral artery Prostaglandins Leukot. Essent. Fatty Acids 74 401 415 10.1016/j.plefa.2006.04.002 1:CAS:528:DC%2BD28XltlKjtb4%3D 16737803 (Pubitemid 43816853)
15. 2 inhibits cAMP production and promotes platelet aggregation J. Clin. Invest. 107 603 610 10.1172/JCI10881 1:CAS:528:DC%2BD3MXhs12ns7c%3D 11238561
16. S. Magder J. Neculcea V. Neculcea R. Sladek 2006 Lipopolysaccharide and TNF-α produce very similar changes in gene expression in human endothelial cells J. Vasc. Res. 43 447 461 10.1159/000095162 1:CAS:528:DC%2BD28Xps1Gntrs%3D 16921252 (Pubitemid 44402083)
17. S.-Q. Wu W. C. Aird 2005 Thrombin, TNF-α, and LPS exert overlapping but nonidentical effects on gene expression in endothelial cells and vascular smooth muscle cells Am. J. Physiol. 289 H873 H885 1:CAS:528:DC%2BD2MXotFejs7o%3D
18. Rozen, S., H. J. Skaletsky 2000. Primer3 on the WWW for general users and for biologist programmers. In Bioinformatics Methods and Protocols: Methods in Molecular Biology, Krawetz S, Misener S, eds. Totowa: Humana Press; 365-386.
19. I. Viani A. Vottero F. Tassi G. Cremonini C. Sartori S. Bernasconi B. Ferrari L. Ghizzoni 2008 Ghrelin Inhibits steroid biosynthesis by cultured granulosa-lutein cells J. Clin. Endocrinol. Metab. 93 1476 1481 10.1210/jc.2007-2063 1:CAS:528:DC%2BD1cXks1agsLg%3D 18230661
20. 3-I receptor isoform Prostaglandins Leukot. Essent. Fatty Acids 77 195 201 10.1016/j.plefa.2007.09. 005 1:CAS:528:DC%2BD2sXhtlGgsL%2FF 18023986 (Pubitemid 350138422)
21. -ΔΔCT method Methods 25 402 408 10.1006/meth.2001.1262 1:CAS:528:DC%2BD38XhtFelt7s%3D 11846609 (Pubitemid 34164012)
22. J. A. Whelan N. B. Russell M. A. Whelan 2003 A method for the absolute quantification of cDNA using real-time PCR J. Immunol. Methods 278 261 269 10.1016/S0022-1759(03)00223-0 1:CAS:528:DC%2BD3sXmvVOht7w%3D 12957413 (Pubitemid 37281208)
23. C. De Vriese F. Gregoire P. De Neef P. Robberecht C. Delporte 2005 Ghrelin is produced by the human erythroleukemic HEL cell line and involved in an autocrine pathway leading to cell proliferation Endocrinology 146 1514 1522 10.1210/en.2004-0964 15564328 (Pubitemid 40289342)
24. R. Wu M. Zhou X. Cui H. H. Simms P. Wang 2004 Upregulation of cardiovascular ghrelin receptor occurs in the hyperdynamic phase of sepsis Am. J. Physiol. 287 H1296 H1302 1:CAS:528:DC%2BD2cXnvVaqsbc%3D
25. A. Li G. Cheng G. H. Zhu A. S. Tarnawski 2007 Ghrelin stimulates angiogenesis in human microvascular endothelial cells: implications beyond GH release Biochem. Biophys. Res. Commun. 353 238 243 10.1016/j.bbrc.2006.11.144 1:CAS:528:DC%2BD2sXhvVSksg%3D%3D 17184731 (Pubitemid 46014561)
26. S. Gnanapavan B. Kola S. A. Bustin D. G. Morris P. McGee P. Fairclough S. Bhattacharya R. Carpenter A. B. Grossman M. Korbonits 2002 The tissue distribution of the mRNA of ghrelin and subtypes of its receptor, GHS-R, in humans J. Clin. Endocrinol. Metab. 87 2988 2991 10.1210/jc.87.6.2988 1:CAS:528:DC%2BD38XkvFaqsbo%3D 12050285 (Pubitemid 34655375)
27. L. Barzon M. Pacenti G. Masi A. L. Stefani K. Fincati G. Palù 2005 Loss of growth hormone secretagogue receptor 1a and overexpression of type 1b receptor transcripts in human adrenocortical tumors Oncology 68 414 421 10.1159/000086983 1:CAS:528:DC%2BD2MXnvFymsrY%3D 16020971 (Pubitemid 41160972)
28. R. M. Luque R. D. Kineman S. Park X. D. Peng F. Gracia-Navarro J. P. Castano M. M. Malagon 2004 Homologous and heterologous regulation of pituitary receptors for ghrelin and growth hormone-releasing hormone Endocrinology 145 3182 3189 10.1210/en.2003-1626 1:CAS:528:DC%2BD2cXltFyks7k%3D 15044357 (Pubitemid 38829989)
29. C. M. Yeung C. B. Chan C. H. K. Cheng 2004 Isolation and characterization of the 5'-flanking region of the growth hormone secretagogue receptor gene from black seabream Acanthopagrus schlegeli Mol. Cell. Endocrinol. 223 5 15 10.1016/j.mce.2004.06.005 1:CAS:528:DC%2BD2cXlvFyrt7c%3D 15279906 (Pubitemid 38992905)
30. M. L. Barreiro L. Pinilla E. Aguilar M. Tena-Sempere 2002 Expression and homologous regulation of GH secretagogue receptor mRNA in rat adrenal gland Eur. J. Endocrinol. 147 677 688 10.1530/eje.0.1470677 1:CAS:528:DC%2BD38XpsVags7w%3D 12444901
31. B. Holst N. D. Holliday A. Bach C. E. Elling H. M. Cox T. W. Schwartz 2004 Common structural basis for constitutive activity of the ghrelin receptor family J. Biol. Chem. 279 53806 53817 10.1074/jbc.M407676200 1:CAS:528:DC%2BD2cXhtVKqu7rE 15383539 (Pubitemid 40051890)
32. D. Mousseaux L. Le Gallic J. Ryan C. Oiry D. Gagne J. A. Fehrentz J. C. Galleyrand J. Martinez 2006 Regulation of ERK1/2 activity by ghrelin-activated growth hormone secretagogue receptor 1A involves a PLC/PKCε pathway Br. J. Pharmacol. 148 350 365 10.1038/sj.bjp.0706727 1:CAS:528:DC%2BD28XltVCjtro%3D 16582936 (Pubitemid 43801182)
33. F. Rossi A. Castelli M. J. Bianco C. Bertone M. Brama V. Santiemma 2008 Ghrelin induces proliferation in human aortic endothelial cells via ERK1/2 and PI3K/Akt activation Peptides 29 2046 2051 10.1016/j.peptides.2008.07.002 1:CAS:528:DC%2BD1cXht12ltL7L 18675863
34. F. Rossi A. Castelli M. J. Bianco C. Bertone M. Brama V. Santiemma 2009 Ghrelin inhibits contraction and proliferation of human aortic smooth muscle cells by cAMP/PKA pathway activation Atherosclerosis 203 97 104 10.1016/j.atherosclerosis.2008.06.015 1:CAS:528:DC%2BD1MXis1CjsL0%3D 18667202
35. J. M. Cao H. Ong C. Chen 2006 Effects of ghrelin and synthetic GH secretagogues on the cardiovascular system Trends Endocrinol. Metab. 17 13 18 10.1016/j.tem.2005.11.004 1:CAS:528:DC%2BD28XhvFynsA%3D%3D 16309920 (Pubitemid 43031379)
36. 2 production in human coronary artery endothelial cells J. Immunol. 179 7899 7906 1:CAS:528:DC%2BD2sXhtlajt7nE 18025237