Fragmentation of human erythrocyte actin following exposure to hypoxia

Acta Haematologica

Volumn 123, Issue 1, 2009, Pages 6-13

  Risso, Angela ^a   Santamaria, Barbara ^b   Pistarino, Erika ^b   Cosulich, Maria Elisabetta ^b,c   Pompach, Petr ^d   Bezouska, Karel ^d   Antonutto, Guglielmo ^a  

^a UNIVERSITY OF UDINE   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

^c UNIVERSITY OF PAVIA   (Italy)

^d INSTITUTE OF MICROBIOLOGY   (Czech Republic)

Author keywords

actin; Thalassaemia; Erythrocytes; Hypoxia; Red blood cells

Indexed keywords

BETA ACTIN; CELL PROTEIN;

ADULT; ALTITUDE; ARTICLE; BETA THALASSEMIA; CASE REPORT; CELL LYSATE; CONTROLLED STUDY; ERYTHROCYTE; ERYTHROCYTE GHOST; ERYTHROCYTE MEMBRANE; FEMALE; HUMAN; HUMAN CELL; HYPOXIA; MALE; MASS SPECTROMETRY; MEMBRANE STRUCTURE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN SECRETION; SEA LEVEL; TWO DIMENSIONAL ELECTROPHORESIS;

ACCLIMATIZATION; ACTINS; ADULT; ALTITUDE; ANOXIA; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; ERYTHROCYTE AGING; ERYTHROCYTE MEMBRANE; ERYTHROCYTES; ERYTHROPOIETIN; FEMALE; FLOW CYTOMETRY; HUMANS; MALE; MOUNTAINEERING; OXIDATIVE STRESS; PEPTIDE FRAGMENTS; PHENOTYPE; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 70449516570     PISSN: 00015792     EISSN: None     Source Type: Journal    
DOI: 10.1159/000256661     Document Type: Article

References (33)

1. Beutler E: Polycythemia; in Beutler E, Lichtmann MA, Coller BS, Kipps TJ, Seligshon U (eds): Williams Hematology, ed 7. New York, Mc-Graw-Hill, 2001, pp 689-702.
2. Risso A, Turello M, Biffoni F, Antonutto G: Red blood cell senescence and neocytolysis in humans after high altitude acclimatisation. Blood Cells Mol Dis 2007; 38: 83-92.
3. Alfrey CP, Rice L, Udden MM, Driscoll T: Neocytolysis: physiological down-regulator of red-cell mass. Lancet 1997; 349: 1389-1390.
4. Rice L, Alfrey CP: Modulation of red cell mass by neocytolysis in space and on Earth. Pflügers Arch 2000; 441:R91-R94.
5. Rice L, Ruiz W, Driscoll T, Whythley MT, Tapia R, Hachey D, Gonzales G, Alfrey CP: Neocytolysis on descent from altitude: a newly recognized mechanism for the control of red cell mass. Ann Intern Med 2001; 134: 652-656.
6. Pascual M, Danielsson C, Steiger G: Proteolytic cleavage of CR1 on human erythrocytes in vivo: evidence for enhanced cleavage in AIDS. Eur J Immunol 1994; 24: 702-708.
7. Willekens FL, Werre JM, Groenen-Döpp YA, Roerdinkholder-Stoelwinder B, de Pauw B, Bosman GJ: Erythrocyte vesiculation: a selfprotective mechanism? Br J Haematol 2007; 141: 549-556.
8. Connor J, Pak CC, and Schroit AJ: Exposure of phosphatidylserine in the outer leaflet of human red blood cells. Relationship to cell density, cell age, and clearance by mononuclear cells. J Biol Chem 1994; 269: 2399-2404.
9. Boas FE, Forman L, Beutler E: Phosphatidylserine exposure and red cell viability in red cell ageing and in hemolytic anemia. Proc Natl Acad Sci USA 1998; 95: 3077-3081.
10. Oldenborg PA, Gresham HD, Chen Y, Izui S, Lindberg FP: Lethal autoimmune hemolytic anemia in CD47-deficient non-obese diabetic (NOD) mice. Blood 2002; 99: 3500-3504.
11. Okazawa H, Motegi S, Ohyama N, Ohnishi H, Tomizawa T, Kaneko Y, Oldenborg PA, Ishikawa O, Matozaki T: Negative regulation of phagocytosis in macrophages by the CD47-SHPS-1 system. J Immunol 2005; 174: 2004-2011.
12. Tsai RK, Discher DE: Inhibition of 'self' engulfment through deactivation of myosin-II at the phagocytic synapse between human cells. J Cell Biol 2008; 180: 989-1003.
13. Tyan YC, Jong SB, Liao JD, Liao PC, Yang MH, Liu CY, Klauser R, Himmelhaus M, Grunze M: Proteomic profiling of erythrocyte proteins by proteolytic digestion chip and identification using two-dimensional electrospray ionization tandem mass spectrometry. J Proteome Res 2005; 4: 748-757. (Pubitemid 40863264)
14. Pasini EM, Kirkegaard M, Mortensen P, Lutz HU, Thomas AW, Mann M: In-depth analysis of the membrane and cytosolic proteome of red blood cells. Blood 2006; 108: 791-801.
15. Mueller TJ, Jackson CW, Dockter ME, Morrison M: Membrane skeletal alterations during in vivo mouse red cell ageing. Increase in the band 4.1a:4.1b ratio. J Clin Invest 1987; 79: 492-499.
16. Minetti G, Ciana A, Profumo A, Zappa M, Vercellati C, Zanella A, Arduini A, Brovelli A: Cell age-related monovalent cations content and density changes in stored human erythrocytes. Biochim Biophys Acta 2001; 1527: 149-155.
17. Marchesi VT, Palade GE: The localization of Mg-Na-K-activated adenosine triphosphatase on red cell ghost membranes. J Cell Biol 1967; 35: 385-404.
18. Risso A, Tell G, Vascotto C, Costessi A, Arena S, Scaloni A, Cosulich ME: Activation of human T lymphocytes under conditions similar to those that occur during exposure to microgravity: a proteomics study. Proteomics 2005; 5: 1827-1837.
19. Draisci R, Montesissa C, Santamaria B, D'Ambrosio C, Ferretti G, Merlanti R, Ferranti C, De Liguoro M, Cartoni C, Pistarino E, Ferrara L, Tiso M, Scaloni A, Cosulich ME: Integrated analytical approach in veal calves administered the anabolic androgenic steroids boldenone and boldione: urine and plasma kinetic profile and changes in plasma protein expression. Proteomics 2007; 7; 3183-3193.
20. Kalfa TA, Pushkaran S, Mohandas N, Hartwig JH, Fowler VM, Johnson JF, Joiner CH, Williams DA, Zheng Y: Rac GTPases regulate the morphology and deformability of the erythrocyte membrane skeleton. Blood 2006; 108: 3637-3645.
21. Low TY, Seow TK, Chung MC: Separation of human erythrocyte membrane associated proteins with one-dimensional and two-dimensional gel electrophoresis followed by identification with matrix-assisted laser desorption/ ionization-time of flight mass spectrometry. Proteomics 2002; 2: 1229-1239.
22. Kakhniashvili DG, Bulla LA Jr, Goodman SR: The human erythrocyte proteome: analysis by ion trap mass spectrometry. Mol Cell Proteomics 2004; 3: 501-509.
23. Yuan J, Bunyaratvej A, Fucharoen S, Fung C, Shinar E, Schrier SL: The instability of the membrane skeleton in thalassemic red blood cells. Blood 1995; 86: 3945-3950.
24. Beutler E: Production and destruction of erythrocytes; in Beutler E, Lichtmann MA, Coller BS, Kipps TJ, Seligshon U (eds): Williams Hematology, ed 7. New York, Mc-Graw-Hill, 2001, pp 355-368.
25. Levy A, Zhang L, Rifkind JM: Hemoglobin: a source of superoxide radical under hypoxic conditions; in Cerutti PA, Fridovich I, Mc-Cord JM (eds): Oxy-Radicals in Molecular Biology and Pathology. UCLA Symposia on Molecular and Cellular Biology, New Series. New York, Liss 1988, pp 11-25.
26. Kiefmann R, Rifkind JM, Nagababu E, Bhattacharya J: Red blood cells induce hypoxic lung inflammation. Blood 2008; 111: 2505-2514.
27. González G, Celedón G, Escobar M, Sotomayor C, Ferrer V, Benítez D, Behn C: Red cell membrane lipid changes at 3,500 m and on return to sea level. High Alt Med Biol 2005; 6: 320-326.
28. D'Amici GM, Rinalducci S, Zolla L: Proteomic analysis of RBC membrane protein degradation during blood storage. J Proteome Res 2007; 6: 3242-3255.
29. Trial J, Rice L, Alfrey CP: Erythropoietin withdrawal alters interactions between young red blood cells, splenic endothelial cells, and macrophages: an in vitro model of neocytolysis. J Investig Med 2001; 49: 335-345.
30. Weatherall DJ: The thalassemias; in Beutler E, Lichtmann MA, Coller BS, Kipps TJ, Seligshon U (eds): Williams Hematology, ed 7. New York, Mc-Graw-Hill, 2001, pp 547-580.
31. Tavazzi D, Duca L, Graziadei G, Comino A, Fiorelli G, Cappellini MD: Membranebound iron contributes to oxidative damage of-thalassaemia intermedia erythrocytes. Br J Haematol 2001; 112: 48-50.
32. Rice L, Alfrey CP, Driscoll T, Whitley CE, Hachey DL, Suki W: Neocytolysis contributes to the anemia of renal disease. Am J Kidney Dis 1999; 33: 59-62.
33. Rice L, Alfrey CP: Modulation of red cell mass by neocytolysis in space and on Earth. Pflügers Arch 2000; 441(suppl 2-3):R91-R94.