Adenovirus-mediated hypoxia-inducible factor 1α double-mutant promotes differentiation of bone marrow stem cells to cardiomyocytes

Journal of Physiological Sciences

Volumn 59, Issue 6, 2009, Pages 413-420

  Wang, Yesong ^a   Feng, Chong ^a   Xue, Jiaojie ^a   Sun, Aijiao ^a   Li, Jun ^a   Wu, Juekan ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

Adenovirus; Bone marrow stem cells; Differentiation; Hypoxia inducible factor 1

Indexed keywords

ADENOVIRUS VECTOR; ALPHA ACTININ; HYPOXIA INDUCIBLE FACTOR 1ALPHA; SMAD4 PROTEIN; TRANSCRIPTION FACTOR GATA 4; TRANSCRIPTION FACTOR NKX2.5; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL DIFFERENTIATION; CELL MUTANT; COCULTURE; CONTROLLED STUDY; DOWN REGULATION; GENE CONSTRUCT; GENE MUTATION; GENE TRANSFER; GENETIC TRANSDUCTION; HEART CELL CULTURE; HEART MUSCLE CELL; IMMUNOHISTOCHEMISTRY; MESENCHYMAL STEM CELL; NEWBORN; NONHUMAN; POLYMERASE CHAIN REACTION; PROTEIN EXPRESSION; PROTEIN STABILITY; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SITE DIRECTED MUTAGENESIS; TRANSCRIPTION INITIATION;

ADENOVIRIDAE; ANIMALS; BIOLOGICAL MARKERS; BONE MARROW CELLS; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CELL SEPARATION; CELLS, CULTURED; FEMUR; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GENETIC VECTORS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MUTATION; MYOCYTES, CARDIAC; RATS; RATS, SPRAGUE-DAWLEY; STEM CELLS; TIBIA; TRANSFECTION;

EID: 70449515939     PISSN: 18806546     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12576-009-0050-x     Document Type: Article

References (22)

1. M Kudo Y Wang MA Wani M Xu A Ayub M Ashraf 2003 Implantation of bone marrow stem cells reduces the infarction and fibrosis in ischemic mouse heart J Mol Cell Cardiol 35 1113 1119 10.1016/S0022-2828(03)00211-6 1:CAS:528: DC%2BD3sXmvVOrsbo%3D 12967634 (Pubitemid 37083255)
2. M Xu M Wani YS Dai J Wang M Yan A Ayub M Ashraf 2004 Differentiation of bone marrow stromal cells into the cardiac phenotype requires intercellular communication with myocytes Circulation 110 2658 2665 10.1161/01.CIR.0000145609. 20435.36 15492307 (Pubitemid 39453016)
3. Z Xu W Jiang A Ma T Wang 2006 Cell-to-cell contact induces mesenchymal stem cell to differentiate into cardiomyocyte and smooth muscle cell Int J Cardiol 109 74 81 10.1016/j.ijcard.2005.05.072 16122823
4. J Yoon WJ Shim YM Ro DS Lim 2005 Transdifferentiation of mesenchymal stem cells into cardiomyocytes by direct cell-to-cell contact with neonatal cardiomyocyte but not adult cardiomyocytes Ann Hematol 84 715 721 10.1007/s00277-005-1068-7 16096830 (Pubitemid 41447805)
5. XJ Xie JA Wang J Cao X Zhang 2006 Differentiation of bone marrow mesenchymal stem cells induced by myocardial medium under hypoxic conditions Acta Pharmacol Sin 27 1153 1158 10.1111/j.1745-7254.2006.00436.x 1:CAS:528:DC%2BD28XpvFahtLk%3D 16923335 (Pubitemid 44410995)
6. C Muscari F Bonafé M Carboni M Govoni I Stanic C Gamberini F Ricci PL Tazzari CM Caldarera C Guarnieri 2008 Difluoromethylornithine stimulates early cardiac commitment of mesenchymal stem cells in a model of mixed culture with cardiomyocytes J Cell Biochem 103 1046 1052 10.1002/jcb.21683 1:CAS:528:DC%2BD1cXjtVynt7c%3D 18240140 (Pubitemid 351342598)
7. RK Bruick SL McKnight 2001 A conserved family of prolyl-4-hydroxylases that modify HIF Science 294 1337 1340 10.1126/science.1066373 1:CAS:528:DC%2BD3MXotlKmtbo%3D 11598268 (Pubitemid 33063099)
8. 2 sensing Science 292 464 468 10.1126/science.1059817 1:CAS:528:DC%2BD3MXjtVentbw%3D 11292862
9. 2-regulated prolyl hydroxylation Science 292 468 472 10.1126/science.1059796 1:CAS:528:DC%2BD3MXjtVentb0%3D 11292861
10. D Lando DJ Peet DA Whelan JJ Gorman ML Whitelaw 2002 Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch Science 295 858 861 10.1126/science.1068592 1:CAS:528:DC%2BD38XhtFemtrs%3D 11823643 (Pubitemid 34118367)
11. Q Ke M Costa 2006 Hypoxia-inducible factor-1 (HIF-1) Mol Pharmacol 70 1469 1480 10.1124/mol.106.027029 1:CAS:528:DC%2BD28XhtFygsbjI 16887934 (Pubitemid 44776406)
12. S Sun Z Guo X Xiao B Liu X Liu PH Tang N Mao 2003 Isolation of mouse marrow mesenchymal progenitors by a novel and reliable method Stem Cells 21 527 535 10.1634/stemcells.21-5-527 1:CAS:528:DC%2BD3sXnvFeisrk%3D 12968107
13. H Reinecke M Zhang T Bartosek CE Murry 1999 Survival, integration, and differentiation of cardiomyocyte grafts: a study in normal and injured rat hearts Circulation 100 193 202 1:STN:280:DyaK1Mzjt1Wqug%3D%3D 10402450
14. SR Cherry D Biniszkiewicz L van Parijs D Baltimore R Jaenisch 2000 Retroviral expression in embryonic stem cells and hematopoietic stem cells Mol Cell Biol 20 7419 7426 10.1128/MCB.20.20.7419-7426.2000 1:CAS:528: DC%2BD3cXnt1aisbk%3D 11003639 (Pubitemid 30736867)
15. T Asano Y Hanazono Y Ueda, et al. 2002 Highly efficient gene transfer into primate embryonic stem cells with a simian lentivirus vector Mol Ther 6 162 168 10.1006/mthe.2002.0655 1:CAS:528:DC%2BD38XmtFaqsro%3D 12161182 (Pubitemid 36336123)
16. 165 gene J Gene Med 10 498 507 10.1002/jgm.1171 1:CAS:528:DC%2BD1cXns1ejtbw%3D 18278825 (Pubitemid 351753519)
17. HM Blau TR Brazelton JM Weimann 2001 The evolving concept of a stem cell: entity or function? Cell 105 829 841 10.1016/S0092-8674(01)00409-3 1:CAS:528:DC%2BD3MXltVeqsbk%3D 11439179 (Pubitemid 32635085)
18. A Behfar LV Zingman DM Hodgson JM Rauzier GC Kane A Terzic M Pucéat 2002 Stem cell differentiation requires a paracrine pathway in the heart FASEB J 16 1558 1566 10.1096/fj.02-0072com 12374778 (Pubitemid 35154638)
19. T Brand WR MacLellan MD Schneider 1993 A dominant-negative receptor for type beta transforming growth factors created by deletion of the kinase domain J Biol Chem 268 11500 11503 1:CAS:528:DyaK3sXks1eqsLg%3D 8389353
20. K Monzen I Shiojima Y Hiroi S Kudoh T Oka E Takimoto D Hayashi T Hosoda A Habara-Ohkubo T Nakaoka T Fujita Y Yazaki I Komuro 1999 Bone morphogenetic proteins induce cardiomyocyte differentiation through the mitogen-activated protein kinase kinase kinase TAK1 and cardiac transcription factors Csx/Nkx-2.5 and GATA-4 Mol Cell Biol 19 7096 7105 1:CAS:528:DyaK1MXmtlalsLk%3D 10490646
21. JD Molkentin C Antos B Mercer T Taigen JM Miano EN Olson 2000 Direct activation of a GATA6 cardiac enhancer by Nkx225: evidence for a reinforcing regulatory network of Nkx225 and GATA transcription factors in the developing heart Dev Biol 217 301 309 10.1006/dbio.1999.9544 1:CAS:528: DC%2BD3cXhs1Wkug%3D%3D 10625555 (Pubitemid 30060878)
22. GB Benoit 2002 Transcriptional regulation of vertebrate cardiac morphogenesis Circ Res 90 509 519 10.1161/01.RES.0000013072.51957.B7 (Pubitemid 34640900)