메뉴 건너뛰기




Volumn 77, Issue 10, 2009, Pages 585-590

Psychiatric effects and side effects of the alpha-2-antagonist yohimbine: Areview of literature and case report;Yohimbin, ein alpha-2-antagonist: Literaturübersicht zu psychiatrisch relevanten Wirkungen und nebenwirkungen mit aktuellem fallbericht

Author keywords

Alcohol; Behaviorial alterations; Cocaine; Suicidality; Yohimbine

Indexed keywords

ALCOHOL; COCAINE; ESCITALOPRAM; MIRTAZAPINE; YOHIMBINE;

EID: 70449440411     PISSN: 07204299     EISSN: 14393522     Source Type: Journal    
DOI: 10.1055/s-0028-1109758     Document Type: Article
Times cited : (2)

References (44)
  • 1
    • 0030803301 scopus 로고    scopus 로고
    • Double-blind, placebo-controlled safety and efficacy trial with yohimbine hydrochloride in the treatment of nonorganic erectile dysfunction
    • Vogt H J., Brandl P, Kockott G, et al. Double-blind, placebo-controlled safety and efficacy trial with yohimbine hydrochloride in the treatment of nonorganic erectile dysfunction. Int J Impot Res 1997 9 (3) 155-161
    • (1997) Int J Impot Res , vol.9 , Issue.3 , pp. 155-161
    • Vogt, H.J.1    Brandl, P.2    Kockott, G.3
  • 2
    • 26844467250 scopus 로고    scopus 로고
    • Therapy for organic erectile Dysfunction
    • Becker A J., Mayer M, Stief C G. Therapy for organic erectile Dysfunction. Urologe A 2005 44 (10) 1160-1166
    • (2005) Urologe A , vol.44 , Issue.10 , pp. 1160-1166
    • Becker, A.J.1    Mayer, M.2    Stief, C.G.3
  • 3
    • 3042809620 scopus 로고    scopus 로고
    • Erectile function disorders. Epidemiology, physiology, etiology, diagnosis and therapy
    • quiz 606 607
    • Derouet H, Osterhage J, Sittinger H. Erectile function disorders. Epidemiology, physiology, etiology, diagnosis and therapy. Nervenarzt 2004 75 (6) 595-605, quiz 606 607
    • (2004) Nervenarzt , vol.75 , Issue.6 , pp. 595-605
    • Derouet, H.1    Osterhage, J.2    Sittinger, H.3
  • 4
    • 70350378796 scopus 로고    scopus 로고
    • Acute neurotoxicity after yohimbine ingestion by a body builder
    • Epub ahead of print 30.7.2009
    • Giampreti A, Lonati D, Locatelli C, et al. Acute neurotoxicity after yohimbine ingestion by a body builder. Clin Toxicol 2009 Epub ahead of print 30.7.2009
    • (2009) Clin Toxicol
    • Giampreti, A.1    Lonati, D.2    Locatelli, C.3
  • 5
    • 67349248129 scopus 로고    scopus 로고
    • Anxiolytics antagonize yohimbine-induced central noradrenergic activity: A concomitant in vivo voltammetry-electrophysiology model of anxiety
    • Crespi F. Anxiolytics antagonize yohimbine-induced central noradrenergic activity: a concomitant in vivo voltammetry-electrophysiology model of anxiety. JNeurosci Methods 2009 180 (1) 97-105
    • (2009) JNeurosci Methods , vol.180 , Issue.1 , pp. 97-105
    • Crespi, F.1
  • 6
    • 67349269511 scopus 로고    scopus 로고
    • Effects of yohimbine and hydrocortisone on panic symptoms, autonomic responses, and attention to threat in healthy adults
    • Vasa R A., Pine D S., Masten C L., et al. Effects of yohimbine and hydrocortisone on panic symptoms, autonomic responses, and attention to threat in healthy adults. Psychopharmacology 2009 204 (3) 445-455
    • (2009) Psychopharmacology , vol.204 , Issue.3 , pp. 445-455
    • Vasa, R.A.1    Pine, D.S.2    Masten, C.L.3
  • 7
    • 70449443914 scopus 로고    scopus 로고
    • Anxiogenic Modulation of Spontaneous and Evoked Neuronal Activity in the Basolateral Amygdala
    • Epub ahead of print 7.7.2009
    • Buffalari D M., Grace A A. Anxiogenic Modulation of Spontaneous and Evoked Neuronal Activity in the Basolateral Amygdala. Neuroscience 2009 Epub ahead of print 7.7.2009
    • (2009) Neuroscience
    • Buffalari, D.M.1    Grace, A.A.2
  • 8
    • 8044229432 scopus 로고    scopus 로고
    • Positron emission tomography measurement of cerebral metabolic correlates of yohimbine administration in combat-related posttraumatic stress disorder
    • Bremner J D., Innis R B., Ng C K., et al. Positron emission tomography measurement of cerebral metabolic correlates of yohimbine administration in combat-related posttraumatic stress disorder. Arch Gen Psychiatry 1997 54 246-254
    • (1997) Arch Gen Psychiatry , vol.54 , pp. 246-254
    • Bremner, J.D.1    Innis, R.B.2    Ng, C.K.3
  • 9
    • 0032811148 scopus 로고    scopus 로고
    • Yohimbine use in a natural setting: Effects on posttraumatic stress disorder
    • Southwick S M., Morgan III C A., Charney D S., et al. Yohimbine use in a natural setting: effects on posttraumatic stress disorder. Biol Psychiatry 1999 46 442-444
    • (1999) Biol Psychiatry , vol.46 , pp. 442-444
    • Southwick, S.M.1    Morgan III, C.A.2    Charney, D.S.3
  • 10
    • 0028946322 scopus 로고
    • Yohimbine facilitated acoustic startle reflex in combat veterans with post-traumatic stress disorder
    • Morgan 3 rd C A., Grillon C, Southwick S M., et al. Yohimbine facilitated acoustic startle reflex in combat veterans with post-traumatic stress disorder. Psychopharmacology 1995 117 466-471
    • (1995) Psychopharmacology , vol.117 , pp. 466-471
    • Morgan III, C.A.1    Grillon, C.2    Southwick, S.M.3
  • 11
    • 0021249631 scopus 로고
    • Noradrenergic function in panic anxiety. Effects of yohimbine in healthy subjects and patients with agoraphobia and panic disorder
    • Charney D S., Heninger G R., Breier A. Noradrenergic function in panic anxiety. Effects of yohimbine in healthy subjects and patients with agoraphobia and panic disorder. Arch Gen Psychiatry 1984 41 751-763
    • (1984) Arch Gen Psychiatry , vol.41 , pp. 751-763
    • Charney, D.S.1    Heninger, G.R.2    Breier, A.3
  • 12
    • 0030738310 scopus 로고    scopus 로고
    • Behavioral, sympathetic and adrenocortical responses to yohimbine in panic disorder patients and normal controls
    • Gurguis G N., Vitton B J., Uhde T W. Behavioral, sympathetic and adrenocortical responses to yohimbine in panic disorder patients and normal controls. Psychiatry Res 1997 71 (1) 27-39
    • (1997) Psychiatry Res , vol.71 , Issue.1 , pp. 27-39
    • Gurguis, G.N.1    Vitton, B.J.2    Uhde, T.W.3
  • 13
    • 27644494282 scopus 로고    scopus 로고
    • The anxiogenic drug yohimbine activates central viscerosensory circuits in rats
    • Myers E A., Banihashemi L, Rinaman L. The anxiogenic drug yohimbine activates central viscerosensory circuits in rats. JComp Neurol 2005 492 (4) 426-441
    • (2005) JComp Neurol , vol.492 , Issue.4 , pp. 426-441
    • Myers, E.A.1    Banihashemi, L.2    Rinaman, L.3
  • 14
    • 0027502731 scopus 로고
    • Yohimbine potentiates active defensive responses to threatening stimuli in Swiss-Webster mice
    • Blanchard R J., Taukulis H K., Rodgers R J., et al. Yohimbine potentiates active defensive responses to threatening stimuli in Swiss-Webster mice. Pharmacol Biochem Behav 1993 44 (3) 673-681
    • (1993) Pharmacol Biochem Behav , vol.44 , Issue.3 , pp. 673-681
    • Blanchard, R.J.1    Taukulis, H.K.2    Rodgers, R.J.3
  • 15
    • 0029619326 scopus 로고
    • Do alpha-2 adrenoceptors modify coping strategies in rats?
    • Haller J, Kiem D T., Makara G B. Do alpha-2 adrenoceptors modify coping strategies in rats? Psychopharmacology 1995 122 (4) 379-385
    • (1995) Psychopharmacology , vol.122 , Issue.4 , pp. 379-385
    • Haller, J.1    Kiem, D.T.2    Makara, G.B.3
  • 16
    • 0142153196 scopus 로고    scopus 로고
    • Neurobiology of suicidal behaviour
    • Mann J J. Neurobiology of suicidal behaviour. Nat Rev Neurosci 2003 4 (10) 819-828
    • (2003) Nat Rev Neurosci , vol.4 , Issue.10 , pp. 819-828
    • Mann, J.J.1
  • 17
    • 3242800444 scopus 로고    scopus 로고
    • An association between a functional polymorphism in the monoamine oxidase a gene promoter, impulsive traits and early abuse experiences
    • Huang Y Y., Cate S P., Battistuzzi C, et al. An association between a functional polymorphism in the monoamine oxidase a gene promoter, impulsive traits and early abuse experiences. Neuropsychopharmacology 2004 29 (8) 1498-1505
    • (2004) Neuropsychopharmacology , vol.29 , Issue.8 , pp. 1498-1505
    • Huang, Y.Y.1    Cate, S.P.2    Battistuzzi, C.3
  • 18
    • 40749106634 scopus 로고    scopus 로고
    • Neurobiology of suicidal behavior. An integration of biological and clinical findings
    • Carballo J J., Akamnonu C P., Oquendo M A. Neurobiology of suicidal behavior. An integration of biological and clinical findings. Arch Suicide Res 2008 12 (2) 93-110
    • (2008) Arch Suicide Res , vol.12 , Issue.2 , pp. 93-110
    • Carballo, J.J.1    Akamnonu, C.P.2    Oquendo, M.A.3
  • 19
    • 58249103062 scopus 로고    scopus 로고
    • Tyrosine hydroxylase immunoreactivity in the locus coeruleus is elevated in violent suicidal depressive patients
    • Gos T, Krell D, Bielau H, et al. Tyrosine hydroxylase immunoreactivity in the locus coeruleus is elevated in violent suicidal depressive patients. Eur Arch Psychiatry Clin Neurosci 2008 258 (8) 513-520
    • (2008) Eur Arch Psychiatry Clin Neurosci , vol.258 , Issue.8 , pp. 513-520
    • Gos, T.1    Krell, D.2    Bielau, H.3
  • 20
    • 0026548740 scopus 로고
    • Alpha 2-adrenoceptors in the brain of suicide victims: Increased receptor density associated with major depression
    • Meana J J., Barturen F, García-Sevilla J A. Alpha 2-adrenoceptors in the brain of suicide victims: increased receptor density associated with major depression. Biol Psychiatry 1992 31 (5) 471-490
    • (1992) Biol Psychiatry , vol.31 , Issue.5 , pp. 471-490
    • Meana, J.J.1    Barturen, F.2    García-Sevilla, J.A.3
  • 21
    • 0036373345 scopus 로고    scopus 로고
    • Neurotransmitter receptor-mediated activation of G-proteins in brains of suicide victims with mood disorders: Selective supersensitivity of alpha(2A)-adrenoceptors
    • González-Maeso J, Rodríguez-Puertas R, Meana J J., et al. Neurotransmitter receptor-mediated activation of G-proteins in brains of suicide victims with mood disorders: selective supersensitivity of alpha(2A)- adrenoceptors. Mol Psychiatry 2002 7 (7) 755-767
    • (2002) Mol Psychiatry , vol.7 , Issue.7 , pp. 755-767
    • González-Maeso, J.1    Rodríguez-Puertas, R.2    Meana, J.J.3
  • 22
    • 0029964826 scopus 로고    scopus 로고
    • Differential age-related loss of pigmented locus coeruleus neurons in suicides, alcoholics, and alcoholic suicides
    • Arango V, Underwood M D., Pauler D K., et al. Differential age-related loss of pigmented locus coeruleus neurons in suicides, alcoholics, and alcoholic suicides. Alcohol Clin Exp Res 1996 20 (7) 1141-1147
    • (1996) Alcohol Clin Exp Res , vol.20 , Issue.7 , pp. 1141-1147
    • Arango, V.1    Underwood, M.D.2    Pauler, D.K.3
  • 23
    • 0028168589 scopus 로고
    • Agonist binding to alpha 2-adrenoceptors is elevated in the locus coeruleus from victims of suicide
    • Ordway G A., Widdowson P S., Smith K S., et al. Agonist binding to alpha 2-adrenoceptors is elevated in the locus coeruleus from victims of suicide. JNeurochem 1994 63 (2) 617-624
    • (1994) JNeurochem , vol.63 , Issue.2 , pp. 617-624
    • Ordway, G.A.1    Widdowson, P.S.2    Smith, K.S.3
  • 24
    • 3242774471 scopus 로고    scopus 로고
    • Increased mRNA expression of alpha2A-adrenoceptors, serotonin receptors and mu-opioid receptors in the brains of suicide victims
    • Escribá P V., Ozaita A, García-Sevilla J A. Increased mRNA expression of alpha2A-adrenoceptors, serotonin receptors and mu-opioid receptors in the brains of suicide victims. Neuropsychopharmacology 2004 29 (8) 1512-1521
    • (2004) Neuropsychopharmacology , vol.29 , Issue.8 , pp. 1512-1521
    • Escribá, P.V.1    Ozaita, A.2    García-Sevilla, J.A.3
  • 25
    • 0027332691 scopus 로고
    • Quantitative autoradiography of alpha 1- and alpha 2-adrenergic receptors in the cerebral cortex of controls and suicide victims
    • Arango V, Ernsberger P, Sved A F., et al. Quantitative autoradiography of alpha 1- and alpha 2-adrenergic receptors in the cerebral cortex of controls and suicide victims. Brain Res 1993 630 (1 2) 271-282
    • (1993) Brain Res , vol.630 , Issue.1-2 , pp. 271-282
    • Arango, V.1    Ernsberger, P.2    Sved, A.F.3
  • 26
    • 33748986163 scopus 로고    scopus 로고
    • Yohimbine may have a therapeutic role in prevention of suicide by regulation of glial fibrillary acidic protein expression
    • Emanuele E, Minoretti P, Arra M. Yohimbine may have a therapeutic role in prevention of suicide by regulation of glial fibrillary acidic protein expression. Med Hypotheses 2006 67 (6) 1472
    • (2006) Med Hypotheses , vol.67 , Issue.6 , pp. 1472
    • Emanuele, E.1    Minoretti, P.2    Arra, M.3
  • 27
    • 33748692894 scopus 로고    scopus 로고
    • Potentiation of cue-induced reinstatement of cocaine-seeking in rats by the anxiogenic drug yohimbine
    • Feltenstein M W., See R E. Potentiation of cue-induced reinstatement of cocaine-seeking in rats by the anxiogenic drug yohimbine. Behav Brain Res 2006 174 (1) 1-8
    • (2006) Behav Brain Res , vol.174 , Issue.1 , pp. 1-8
    • Feltenstein, M.W.1    See, R.E.2
  • 28
    • 57449091509 scopus 로고    scopus 로고
    • Effects of repeated yohimbine and extinction and reinstatement of cocaine seeking
    • Kupferschmidt D A., Tribe E, Erb S. Effects of repeated yohimbine and extinction and reinstatement of cocaine seeking. Pharmacol Biochem Behav 2009 91 473-480
    • (2009) Pharmacol Biochem Behav , vol.91 , pp. 473-480
    • Kupferschmidt, D.A.1    Tribe, E.2    Erb, S.3
  • 29
    • 39049140269 scopus 로고    scopus 로고
    • Alpha 1-noradrenergic system role in increased motivation for cocaine intake in rats with prolonged access
    • Wee S, Mandyam C D., Lekic D M., et al. Alpha 1-noradrenergic system role in increased motivation for cocaine intake in rats with prolonged access. Eur Neuropsychopharmacol 2008 18 303-311
    • (2008) Eur Neuropsychopharmacol , vol.18 , pp. 303-311
    • Wee, S.1    Mandyam, C.D.2    Lekic, D.M.3
  • 30
    • 33749546915 scopus 로고    scopus 로고
    • Alpha-noradrenergic receptors modulate the development and expression of cocaine sensitization
    • Jiménez-Rivera C A., Feliu-Mojer M, Vázquez-Torres R. Alpha-noradrenergic receptors modulate the development and expression of cocaine sensitization. Ann N Y Acad Sci 2006 1074 390-402
    • (2006) Ann N y Acad Sci , vol.1074 , pp. 390-402
    • Jiménez-Rivera, C.A.1    Feliu-Mojer, M.2    Vázquez-Torres, R.3
  • 31
    • 51649086961 scopus 로고    scopus 로고
    • Yohimbine impairs extinction of cocaine-conditioned place preference in an alpha2-adrenergic receptor independent process
    • Davis A R., Shields A D., Brigman J L., et al. Yohimbine impairs extinction of cocaine-conditioned place preference in an alpha2-adrenergic receptor independent process. Learn Mem 2008 15 667-776
    • (2008) Learn Mem , vol.15 , pp. 667-776
    • Davis, A.R.1    Shields, A.D.2    Brigman, J.L.3
  • 32
    • 61849166294 scopus 로고    scopus 로고
    • Conditioned cues and yohimbine induce reinstatement of beer and near-beer seeking in Long-Evans rats
    • Richards J K., Simms J A., Bartlett S E. Conditioned cues and yohimbine induce reinstatement of beer and near-beer seeking in Long-Evans rats. Addict Biol 2009 14 144-151
    • (2009) Addict Biol , vol.14 , pp. 144-151
    • Richards, J.K.1    Simms, J.A.2    Bartlett, S.E.3
  • 33
    • 46149118191 scopus 로고    scopus 로고
    • Inhibition of orexin-1 /hypocretin-1 receptors inhibits yohimbine-induced reinstatement of ethanol and sucrose seeking in Long-Evans rats
    • Richards J K., Simms J A., Steensland P, et al. Inhibition of orexin-1 /hypocretin-1 receptors inhibits yohimbine-induced reinstatement of ethanol and sucrose seeking in Long-Evans rats. Psychopharmacology 2008 199 109-117
    • (2008) Psychopharmacology , vol.199 , pp. 109-117
    • Richards, J.K.1    Simms, J.A.2    Steensland, P.3
  • 34
    • 36349035455 scopus 로고    scopus 로고
    • The CRF1 receptor antagonist antalarmin attenuates yohimbine-induced increases in operant alcohol self-administration and reinstatement of alcohol seeking in rats
    • Marinelli P W., Funk D, Juzytsch W, et al. The CRF1 receptor antagonist antalarmin attenuates yohimbine-induced increases in operant alcohol self-administration and reinstatement of alcohol seeking in rats. Psychopharmacology 2007 195 345-355
    • (2007) Psychopharmacology , vol.195 , pp. 345-355
    • Marinelli, P.W.1    Funk, D.2    Juzytsch, W.3
  • 35
    • 67349192594 scopus 로고    scopus 로고
    • The role of noradrenaline and 5-hydroxytryptamine in yohimbine-induced increases in alcohol-seeking in rats
    • Dzung L e A, Funk D, Harding S, et al. The role of noradrenaline and 5-hydroxytryptamine in yohimbine-induced increases in alcohol-seeking in rats. Psychopharmacology 2009 204 477-488
    • (2009) Psychopharmacology , vol.204 , pp. 477-488
    • Dzung, L.E.A.1    Funk, D.2    Harding, S.3
  • 36
    • 0028912091 scopus 로고
    • Noradrenergic response to acute ethanol administration in healthy subjects: Comparison with intravenous yohimbine
    • McDougle C J., Krystal J H., Price L H., et al. Noradrenergic response to acute ethanol administration in healthy subjects: comparison with intravenous yohimbine. Psychopharmacology 1995 118 127-135
    • (1995) Psychopharmacology , vol.118 , pp. 127-135
    • McDougle, C.J.1    Krystal, J.H.2    Price, L.H.3
  • 37
    • 0037090655 scopus 로고    scopus 로고
    • Yohimbine-induced withdrawal and anxiety symptoms in opioid-dependent patients
    • Stine S M., Southwick S M., Petrakis I L., et al. Yohimbine-induced withdrawal and anxiety symptoms in opioid-dependent patients. Biol Psychiatry 2002 51 642-651
    • (2002) Biol Psychiatry , vol.51 , pp. 642-651
    • Stine, S.M.1    Southwick, S.M.2    Petrakis, I.L.3
  • 38
    • 57349111876 scopus 로고    scopus 로고
    • Low doses of alpha 2-adrenoreceptor antagonists augment spinal morphine analgesia and inhibit development of acute and chronic tolerance
    • Milne B, Sutak M, Cahill C M., et al. Low doses of alpha 2-adrenoreceptor antagonists augment spinal morphine analgesia and inhibit development of acute and chronic tolerance. Br J Pharmacol 2008 155 1264-1278
    • (2008) Br J Pharmacol , vol.155 , pp. 1264-1278
    • Milne, B.1    Sutak, M.2    Cahill, C.M.3
  • 39
    • 60749097365 scopus 로고    scopus 로고
    • Facilitation of fear extinction in phobic participants with a novel cognitive enhancer: A randomized placebo controlled trial of yohimbine augmentation
    • Powers M B., Smits J A., Otto M W., et al. Facilitation of fear extinction in phobic participants with a novel cognitive enhancer: a randomized placebo controlled trial of yohimbine augmentation. JAnxiety Disord 2009 23 350-356
    • (2009) JAnxiety Disord , vol.23 , pp. 350-356
    • Powers, M.B.1    Smits, J.A.2    Otto, M.W.3
  • 40
    • 67349185545 scopus 로고    scopus 로고
    • The effects of yohimbine and amphetamine on fear expression and extinction in rats
    • Mueller D, Olivera-Figueroa L A., Pine D S., et al. The effects of yohimbine and amphetamine on fear expression and extinction in rats. Psychopharmacology 2009 204 599-606
    • (2009) Psychopharmacology , vol.204 , pp. 599-606
    • Mueller, D.1    Olivera-Figueroa, L.A.2    Pine, D.S.3
  • 41
    • 62949115816 scopus 로고    scopus 로고
    • Therapeutic potential of alpha2 adrenoreceptor antagonism for antipsychotic-induced extrapyramidal motor disorders
    • Imaki J, Mae Y, Shimizu S, et al. Therapeutic potential of alpha2 adrenoreceptor antagonism for antipsychotic-induced extrapyramidal motor disorders. Neurosci Lett 2009 454 143-147
    • (2009) Neurosci Lett , vol.454 , pp. 143-147
    • Imaki, J.1    Mae, Y.2    Shimizu, S.3
  • 42
    • 2442648802 scopus 로고    scopus 로고
    • Addition of the alpha2-antagonist yohimbine to fluoxetine: Effects on rate of antidepressant response
    • Sanacora G, Berman R M., Cappiello A, et al. Addition of the alpha2-antagonist yohimbine to fluoxetine: effects on rate of antidepressant response. Neuropsychopharmacology 2004 29 1166-1171
    • (2004) Neuropsychopharmacology , vol.29 , pp. 1166-1171
    • Sanacora, G.1    Berman, R.M.2    Cappiello, A.3
  • 43
    • 0037120279 scopus 로고    scopus 로고
    • Sleep-wake effects of yohimbine and atropine in rats with a clomipramine-based model of depression
    • Mavanji V, Datta S. Sleep-wake effects of yohimbine and atropine in rats with a clomipramine-based model of depression. Neuroreport 2002 13 1603-1606
    • (2002) Neuroreport , vol.13 , pp. 1603-1606
    • Mavanji, V.1    Datta, S.2
  • 44
    • 43049157802 scopus 로고    scopus 로고
    • Norepinephrine signaling through beta-adrenergic receptors is critical for expression of cocaine-induced anxiety
    • 012
    • Schank J R., Liles L C., Weinshenker D. Norepinephrine signaling through beta-adrenergic receptors is critical for expression of cocaine-induced anxiety. Biol Psychiatry 2008 63 1007-10 012
    • (2008) Biol Psychiatry , vol.63 , pp. 1007-10
    • Schank, J.R.1    Liles, L.C.2    Weinshenker, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.