Inhibitory effects of the ethanol extract of Gleditsia sinensis thorns on human colon cancer HCT116 cells in vitro and in vivo

Oncology Reports

Volumn 22, Issue 6, 2009, Pages 1505-1512

  Lee, Se Jung ^a,b   Cho, Young Hwa ^c   Kim, Heejong ^c   Park, Keerang ^c   Park, Sung Kyu ^d   Ha, Sang Do ^b   Kim, Wun Jae ^d   Moon, Sung Kwon ^a  

^a Chungju National University   (South Korea)

^b Chung Ang University   (South Korea)

^c Juseong College   (South Korea)

^d Chungbuk National University College of Medicine   (South Korea)

Author keywords

Colon cancer; Extracellular signal regulated kinases; G2 M phase cell cycle arrest; Gleditsia sinensis thorns; Matrix; p27

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ALCOHOL; CYCLIN DEPENDENT KINASE; CYCLINE; GELATINASE B; GLEDITSIA SINENSIS EXTRACT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PLANT EXTRACT; PROTEIN P27; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR AP 1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL PROLIFERATION; CELL STRAIN HCT116; COLON CANCER; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFICACY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GLEDITSIA SINENSIS; HERBAL MEDICINE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SOLVENT EXTRACTION; TUMOR XENOGRAFT; UPREGULATION;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL CYCLE; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; ETHANOL; GLEDITSIA; HUMANS; INHIBITORY CONCENTRATION 50; MATRIX METALLOPROTEINASE 9; MICE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PLANT EXTRACTS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 70449370051     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or_00000594     Document Type: Article

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