The m.3243A>G mtDNA mutation is pathogenic in an in vitro model of the human blood brain barrier

Mitochondrion

Volumn 9, Issue 6, 2009, Pages 463-470

  Davidson, Mercy M ^a   Walker, Winsome F ^a   Hernandez Rosa, Evelyn ^a  

^a New York Presbyterian Morgan Stanley Children's Hospital   (United States)

Author keywords

Astrocytes; Blood brain barrier; Cell culture model; Endothelial cells; MELAS; Stroke

Indexed keywords

ADENINE; CYTOCHROME C OXIDASE; GUANINE; MITOCHONDRIAL DNA; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SUCCINATE DEHYDROGENASE (UBIQUINONE);

ARTICLE; ASTROCYTE; BLOOD BRAIN BARRIER; BRAIN CAPILLARY; CELL ACTIVITY; CONTROLLED STUDY; ELECTRIC RESISTANCE; ENDOTHELIUM CELL; ENZYME ACTIVITY; FETUS; GENE MUTATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; MELAS SYNDROME; MEMBRANE PERMEABILITY; MITOCHONDRIAL RESPIRATION; PRIORITY JOURNAL; RESPIRATORY CHAIN; TISSUE CULTURE TECHNIQUE;

ASTROCYTES; BLOOD-BRAIN BARRIER; CELL CULTURE TECHNIQUES; CELL LINE; DNA, MITOCHONDRIAL; ELECTRIC IMPEDANCE; ELECTRON TRANSPORT; ENDOTHELIAL CELLS; HUMANS; MELAS SYNDROME; PERMEABILITY; POINT MUTATION; RNA, TRANSFER, LEU;

EID: 70449109172     PISSN: 15677249     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mito.2009.08.006     Document Type: Article

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