IGF-1 receptor transactivation mediates Src-dependent cortactin phosphorylation in response to angiotensin II

Canadian Journal of Physiology and Pharmacology

Volumn 87, Issue 10, 2009, Pages 805-812

  Zahradka, Peter ^a,b   Storie, Benjamin ^b   Wright, Brenda ^b  

^a UNIVERSITY OF MANITOBA   (Canada)

^b ST BONIFACE GENERAL HOSPITAL RESEARCH CENTRE   (Canada)

Author keywords

Angiotensin; Cortactin; Cytoskeleton; IGF 1 receptor; Smooth muscle; Src kinase

Indexed keywords

3 BROMO 5 TERT BUTYL 4 HYDROXYBENZYLIDENEMALONONITRILE; 4 AMINO 7 TERT BUTYL 5 (4 METHYLPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; ACTIN RELATED PROTEIN 3; ANGIOTENSIN II; CORTACTIN; PROTEIN TYROSINE KINASE; SOMATOMEDIN C RECEPTOR;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; ENZYME ACTIVATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; SMOOTH MUSCLE FIBER; SWINE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ACTIN-RELATED PROTEIN 3; ANGIOTENSIN II; ANIMALS; BLOTTING, WESTERN; CORTACTIN; FLUORESCENT ANTIBODY TECHNIQUE; IMMUNOPRECIPITATION; PHOSPHORYLATION; PROTEIN KINASE C; RECEPTOR, IGF TYPE 1; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA; SRC-FAMILY KINASES; SWINE; TRANSCRIPTIONAL ACTIVATION; TYRPHOSTINS;

EID: 70449086337     PISSN: 00084212     EISSN: None     Source Type: Journal    
DOI: 10.1139/Y09-052     Document Type: Article

References (45)

1. Albinsson, S., and Hellstrand, P. 2007. Integration of signal pathways for stretch-dependent growth and differentiation in vascular smooth muscle. Am. J. Physiol. Cell Physiol. 293(2): C772- C782. doi:10.1152/ajpcell.00622.2006. PMID:17507430.
2. Albinsson, S., Nordström, I., and Hellstrand, P. 2004. Stretch of the vascular wall induces smooth muscle differentiation by promoting actin polymerization. J. Biol. Chem. 279(33): 34849-34855. doi:10.1074/jbc.M403370200. PMID:15184395.
3. Ammer, A.G., and Weed, S.A. 2008. Cortactin branches out: roles in regulating protrusive actin dynamics. Cell Motil. Cytoskeleton, 65(9): 687-707. doi:10.1002/cm.20296. PMID:18615630.
4. Artym, V.V., Zhang, Y., Seillier-Moiseiwitsch, F., Yamada, K.M., and Mueller, S.C. 2006. Dynamic interactions of cortactin and membrane type 1 matrix metalloproteinase at invadopodia: defining the stages of invadopodia formation and function. Cancer Res. 66(6): 3034-3043. doi:10.1158/0008-5472.CAN-05-2177. PMID:16540652.
5. Ayala, I., Baldassarre, M., Giacchetti, G., Caldieri, G., Tete, S., Luini, A., and Buccione, R. 2008. Multiple regulatory inputs converge on cortactin to control invadopodia biogenesis and extracellular matrix degradation. J. Cell Sci. 121(Pt 3): 369-378. doi:10.1242/jcs.008037. PMID:18198194. (Pubitemid 351356708)
6. Baldassarre, M., Ayala, I., Beznoussenko, G., Giacchetti, G., Machesky, L.M., Luini, A., and Buccione, R. 2006. Actin dynamics at sites of extracellular matrix degradation. Eur. J. Cell Biol. 85(12): 1217-1231. doi:10.1016/j.ejcb. 2006.08.003. PMID:17010475.
7. Boccardi, C., Cecchettini, A., Caselli, A., Camici, G., Evangelista, M., Mercatanti, A., et al. 2007. A proteomic approach to the investigation of early events involved in the activation of vascular smooth muscle cells. Cell Tissue Res. 329(1): 119-128. doi:10. 1007/s00441-007-0407-5. PMID:17406898. (Pubitemid 46686111)
8. Bornfeldt, K.E., Raines, E.W., Nakano, T., Graves, L.M., Krebs, E.G., and Ross, R. 1994. Insulin-like growth factor-I and platelet-derived growth factor-BB induce directed migration of human arterial smooth muscle cells via signaling pathways that are distinct from those of proliferation. J. Clin. Invest. 93(3): 1266-1274. doi:10.1172/JCI117081. PMID:8132765.
9. Cai, X. 2006. Regulation of smooth muscle cells in development and vascular disease: current therapeutic strategies. Expert Rev. Cardiovasc. Ther. 4(6): 789-800. doi:10.1586/14779072.4.6.789. PMID:17173496.
10. Clark, E.S., and Weaver, A.M. 2008. A new role for cortactin in invadopodia: regulation of protease secretion. Eur. J. Cell Biol. 87(8- 9): 581-590. doi:10.1016/j.ejcb.2008.01.008. PMID:18342393.
11. Dzau, V.J. 2001. Theodore Cooper Lecture: Tissue angiotensin and pathobiology of vascular disease: a unifying hypothesis. Hypertension, 37(4): 1047-1052. PMID:11304501.
12. Fernstrom, K., Farmer, P., and Ali, M.S. 2005. Cytoskeletal remodeling in vascular smooth muscle cells in response to angiotensin II-induced activation of the SHP-2 tyrosine phosphatase. J. Cell. Physiol. 205(3): 402-413. doi:10.1002/jcp.20436. PMID:16021628.
13. Furmaniak-Kazmierczak, E., Crawley, S.W., Carter, R.L., Maurice, D.H., and Côté, G.P. 2007. Formation of extracellular matrix-digesting invadopodia by primary aortic smooth muscle cells. Circ. Res. 100(9): 1328-1336. doi:10.1161/Circresaha.106. 147744. PMID:17446433.
14. Gerthoffer, W.T. 2007. Mechanisms of vascular smooth muscle cell migration. Circ. Res. 100(5): 607-621. doi:10.1161/01.RES. 0000258492.96097.47. PMID:17363707.
15. Hauck, C.R., Hsia, D.A., Ilic, D., and Schlaepfer, D.D. 2002. v-Src SH3-enhanced interaction with focal adhesion kinase at beta 1 integrin-containing invadopodia promotes cell invasion. J. Biol. Chem. 277(15): 12487-12490. doi:10.1074/jbc.C100760200. PMID:11839732.
16. Higuchi, S., Ohtsu, H., Suzuki, H., Shirai, H., Frank, G.D., and Eguchi, S. 2007. Angiotensin II signal transduction through the AT1 receptor: novel insights into mechanisms and pathophysiology. Clin. Sci. (Lond.), 112(8): 417-428. PMID:17346243.
17. Hsieh, H.L., Sun, C.C., Wang, T.S., and Yang, C.M. 2008. PKC- delta/c-Src-mediated EGF receptor transactivation regulates thrombin-induced COX-2 expression and PGE(2) production in rat vascular smooth muscle cells. Biochim. Biophys. Acta, 1783(9): 1563-1575. doi:10.1016/j.bbamcr.2008.03.016. PMID: 18452714.
18. Huang, C., Ni, Y., Wang, T., Gao, Y., Haudenschild, C.C., and Zhan, X. 1997. Down-regulation of the filamentous actin cross-linking activity of cortactin by Src-mediated tyrosine phosphorylation. J. Biol. Chem. 272(21): 13911-13915. doi:10.1074/jbc.272.21.13911. PMID:9153252.
19. Itoh, Y. 2006. MT1-MMP: a key regulator of cell migration in tissue. IUBMB Life, 58(10): 589-596. doi:10.1080/ 15216540600962818. PMID:17050376. (Pubitemid 44527223)
20. Jiménez, C., Portela, R.A., Mellado, M., Rodríguez-Frade, J.M., Collard, J., Serrano, A., et al. 2000. Role of the PI3K regulatory subunit in the control of actin organization and cell migration. J. Cell Biol. 151(2): 249-262. doi:10.1083/jcb. 151.2.249. PMID: 11038173. (Pubitemid 30787222)
21. Junaid, A., Moon, M.C., Harding, G.E., and Zahradka, P. 2007. Osteopontin localizes to the nucleus of 293 cells and associates with polo-like kinase-1. Am. J. Physiol. Cell Physiol. 292(2): C919-C926. doi:10.1152/ajpcell.00477.2006. PMID:17005603.
22. Langlois, S., Nyalendo, C., Di Tomasso, G., Labrecque, L., Roghi, C., Murphy, G., et al. 2007. Membrane-type 1 matrix metalloproteinase stimulates cell migration through epidermal growth factor receptor transactivation. Mol. Cancer Res. 5(6): 569-583. doi:10.1158/1541-7786.MCR-06-0267. PMID:17541067.
23. Li, W., Jiang, Y.X., Zhang, J., Soon, L., Flechner, L., Kapoor, V., et al. 1998. Protein kinase C-delta is an important signaling molecule in insulin-like growth factor I receptor-mediated cell transformation. Mol. Cell. Biol. 18(10): 5888-5898. PMID: 9742106.
24. Moon, M.C., Yau, L., Wright, B., and Zahradka, P. 2008. Injury- induced expression of cytokeratins 8 and 18 by vascular smooth muscle cells requires concurrent activation of cytoskeletal and growth factor receptors. Can. J. Physiol. Pharmacol. 86(5): 223- 231. doi:10.1139/Y08-019. PMID:18432282.
25. Mureebe, L., Nelson, P.R., Yamamura, S., Lawitts, J., and Kent, K.C. 1997. Activation of pp60c-src is necessary for human vascular smooth muscle cell migration. Surgery, 122(2): 138-144, discussion 144-145. doi:10.1016/S0039- 6060(97)90002-7. PMID:9288116. (Pubitemid 27383049)
26. Nakashima, H., Suzuki, H., Ohtsu, H., Chao, J.Y., Utsunomiya, H., Frank, G.D., and Eguchi, S. 2006. Angiotensin II regulates vascular and endothelial dysfunction: recent topics of Angiotensin II type-1 receptor signaling in the vasculature. Curr. Vasc. Pharmacol. 4(1): 67-78. doi:10.2174/157016106775203126. PMID: 16472178.
27. Natarajan, K., Yin, G., and Berk, B.C. 2004. Scaffolds direct Src- specific signaling in response to angiotensin II: new roles for Cas and GIT1. Mol. Pharmacol. 65(4): 822-825. doi:10.1124/ mol.65.4.822. PMID:15044610.
28. Nyalendo, C., Michaud, M., Beaulieu, E., Roghi, C., Muiphy, G., Gingras, D., and Béliveau, R. 2007. Src-dependent phosphorylation of membrane type I matrix metalloproteinase on cytoplasmic tyrosine 573: role in endothelial and tumor cell migration. J. Biol. Chem. 282(21): 15690-15699. doi:10.1074/jbc. M608045200. PMID:17389600.
29. Owens, G.K. 2007. Molecular control of vascular smooth muscle cell differentiation and phenotypic plasticity. Novartis Found. Symp. 283: 174-191, discussion 191-193, 238-241. doi:10. 1002/9780470319413.ch14. PMID:18300422.
30. Rice, D.C., Dobrian, A.D., Schriver, S.D., and Prewitt, R.L. 2002. Src autophosphorylation is an early event in pressure-mediated signaling pathways in isolated resistance arteries. Hypertension, 39(2 Pt 2): 502-507. doi:10.1161/hy0202.102834. PMID: 11882598.
31. Rosendorff, C. 1996. The renin-angiotensin system and vascular hypertrophy. J. Am. Coll. Cardiol. 28(4): 803-812. doi:10.1016/ S0735-1097(96)00251-253 PMID:8837552.
32. Ruiz-Ortega, M., Ruperez, M., Esteban, V., and Egido, J. 2003. Molecular mechanisms of angiotensin II-induced vascular injury. Curr. Hypertens. Rep. 5(1): 73-79. doi:10.1007/s11906-003- 0014-20 PMID:12530939.
33. Rzucidlo, E.M., Martin, K.A., and Powell, R.J. 2007. Regulation of vascular smooth muscle cell differentiation. J. Vasc. Surg. 45(6 Suppl A): A25-A32. doi:10.1016/j.jvs.2007.03.001. PMID:17544021.
34. Saward, L., and Zahradka, P. 1997. Coronary artery smooth muscle in culture: migration of heterogeneous cell populations from vessel wall. Mol. Cell. Biochem. 176(1-2): 53-59. doi:10.1023/ A: 1006870827516. PMID:9406145.
35. Tehrani, S., Tomasevic, N., Weed, S., Sakowicz, R., and Cooper, J.A. 2007. Src phosphorylation of cortactin enhances actin assembly. Proc. Natl. Acad. Sci. U.S.A. 104(29): 11933-11938. doi:10.1073/pnas.0701077104. PMID:17606906.
36. Touyz, R.M., Wu, X.H., He, G., Salomon, S., and Schiffrin, E.L. 2002. Increased angiotensin II-mediated Src signaling via epidermal growth factor receptor transactivation is associated with decreased C-terminal Src kinase activity in vascular smooth muscle cells from spontaneously hypertensive rats. Hypertension, 39(2 Pt 2): 479-485. doi:10.1161/hy02t2.102909. PMID: 11882594. (Pubitemid 34165169)
37. Van Kolen, K., Gilany, K., Moens, L., Esmans, E.L., and Siegers, H. 2006. P2Y12 receptor signalling towards PKB proceeds through IGF-1 receptor cross-talk and requires activation of Src, Pyk2 and Rap1. Cell. Signal. 18(8): 1169-1181. doi:10.1016/j. cellsig.2005.09.005. PMID:16236484.
38. Vuori, K., and Ruoslahti, E. 1995. Tyrosine phosphorylation of p130Cas and cortactin accompanies integrin-mediated cell adhesion to extracellular matrix. J. Biol. Chem. 270(38): 22259- 22262. doi:10.1074/jbc.270.38.22259. PMID:7545676.
39. Weaver, A.M. 2008. Cortactin in tumor invasiveness. Cancer Lett. 265(2): 157-166. doi:10.1016/j.canlet.2008.02.066. PMID: 18406052.
40. Wu, H., Reynolds, A.B., Kanner, S.B., Vines, R.R., and Parsons, J.T. 1991. Identification and characterization of a novel cytoskeleton-associated pp60src substrate. Mol. Cell. Biol. 11(10): 5113-5124. PMID:1922035.
41. Yamboliev, I.A., Chen, J., and Gerthoffer, W.T. 2001. PI 3-kinases and Src kinases regulate spreading and migration of cultured VSMCs. Am. J. Physiol. Cell Physiol. 281(2): C709-C718. PMID:11443070.
42. Yau, L., and Zahradka, P. 2003. PGE(2) stimulates vascular smooth muscle cell proliferation via the EP2 receptor. Mol. Cell. Endocrinol. 203(1-2): 77-90. doi:10.1016/S0303-7207(03)00096-0. PMID:12782405.
43. Yau, L., Litchie, B., Thomas, S., Storie, B., Yurkova, N., and Zahradka, P. 2003. Endogenous mono-ADP-ribosylation mediates smooth muscle cell proliferation and migration via protein kinase N-dependent induction of c-fos expression. Eur. J. Biochem. 270(1): 101-110. doi:10.1046/j.1432-1033.2003. 03366.x. PMID:12492480.
44. Zahradka, P., Harding, G., Litchie, B., Thomas, S., Werner, J.P., Wilson, D.P., and Yurkova, N. 2004a. Activation of MMP-2 in response to vascular injury is mediated by phosphatidyhnositol 3-kinase-dependent expression of MT1-MMP. Am. J. Physiol. Heart Circ. Physiol. 287(6): H2861-H2870. doi:10.1152/ ajpheart.00230.2004. PMID:15297252.
45. Zahradka, P., Litchie, B., Storie, B., and Helwer, G. 2004b. Transactivation of the insulin-like growth factor-I receptor by angiotensin II mediates downstream signaling from the angiotensin II type 1 receptor to phosphatidylinositol 3-kinase. Endocrinology, 145(6): 2978-2987. doi:10.1210/en.2004-0029. PMID:14976148. (Pubitemid 38686247)