Inhibition of the human chemokine receptor CCR5 by variecolin and variecolol and isolation of four new variecolin analogues, emericolins A-D, from Emericella aurantiobrunnea

Journal of Natural Products

Volumn 67, Issue 10, 2004, Pages 1681-1684

  Yoganathan, K ^a   Rossant, Christine ^a   Glover, Robert P ^a   Cao, Shugeng ^a   Vittal, Jagadese J ^b   Ng, Siewbee ^a   Huang, Yicun ^a   Buss, Antony D ^a   Butler, Mark S ^a  

^a MerLion Pharmaceuticals Pte Ltd   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CCR5; EMERICOLIN A; EMERICOLIN B; EMERICOLIN C; EMERICOLIN D; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; PROTEIN INHIBITOR; UNCLASSIFIED DRUG; VARIECOLIN; VARIECOLOL;

ARTICLE; ASSAY; BIOASSAY; CRYSTAL STRUCTURE; DRUG ISOLATION; EMERICELLA AURANTIOBRUNNEA; FRACTIONATION; FUNGUS; IC 50; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PROTEIN BINDING; SCINTILLATION PROXIMITY ASSAY; SPECTRUM; STEREOCHEMISTRY; X RAY ANALYSIS;

ASCOMYCOTA; CRYSTALLOGRAPHY, X-RAY; HUMANS; INHIBITORY CONCENTRATION 50; MACROPHAGE INFLAMMATORY PROTEIN-1; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; RECEPTORS, CCR5; TERPENES;

EMERICELLA; EMERICELLA AURANTIOBRUNNEA; FUNGI;

EID: 7044262881     PISSN: 01633864     EISSN: None     Source Type: Journal    
DOI: 10.1021/np049844c     Document Type: Article

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