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Volumn 114, Issue 5-6 SPEC. ISS., 2004, Pages 371-382

Anti-phospholipid antibodies (aPL) and apoptosis: Prothrombin-dependent aPL as a paradigm for phospholipid-dependent interactions with apoptotic cells

Author keywords

Anti phospholipid antibodies; Apoptotic cells; beta; 2 glycoprotein I; Lupus anticoagulant antibodies; Prothrombin; Systemic lupus erythematosus

Indexed keywords

CHORIONIC GONADOTROPIN; GLYCOPROTEIN IIB; MONOCLONAL ANTIBODY; PHOSPHOLIPID; PHOSPHOLIPID ANTIBODY; PROTHROMBIN;

EID: 7044234652     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.thromres.2004.08.007     Document Type: Conference Paper
Times cited : (6)

References (42)
  • 1
    • 0021029327 scopus 로고
    • Anticardiolipin antibodies: Detection by radioimmunoassay and association with thrombosis in systemic lupus erythematosus
    • E.N. Harris, A.E. Gharavi, M.L. Boey, B.M. Patel, C.G. Mackworth-Young, and S. Loizou Anticardiolipin antibodies: detection by radioimmunoassay and association with thrombosis in systemic lupus erythematosus Lancet 2 1983 1211 1214
    • (1983) Lancet , vol.2 , pp. 1211-1214
    • Harris, E.N.1    Gharavi, A.E.2    Boey, M.L.3    Patel, B.M.4    MacKworth-Young, C.G.5    Loizou, S.6
  • 3
    • 0029814955 scopus 로고    scopus 로고
    • Immunology of the antiphospholipid antibody syndrome
    • R.A.S. Roubey Immunology of the antiphospholipid antibody syndrome Arthritis Rheum. 39 1996 1444 1454
    • (1996) Arthritis Rheum. , vol.39 , pp. 1444-1454
    • Roubey, R.A.S.1
  • 4
    • 0025332717 scopus 로고
    • Anti-phospholipid antibodies are directed against a complex antigen that includes a lipid-binding inhibitor of coagulation: β2-glycoprotein I (apolipoprotein H)
    • H.P. McNeil, R.J. Simpson, C.N. Chesterman, and S.A. Krilis Anti-phospholipid antibodies are directed against a complex antigen that includes a lipid-binding inhibitor of coagulation: β2-glycoprotein I (apolipoprotein H) Proc. Natl. Acad. Sci. U. S. A. 87 1990 4120 4124
    • (1990) Proc. Natl. Acad. Sci. U. S. A. , vol.87 , pp. 4120-4124
    • McNeil, H.P.1    Simpson, R.J.2    Chesterman, C.N.3    Krilis, S.A.4
  • 6
    • 0001644081 scopus 로고
    • Prothrombin as co-factor of the circulating anticoagulant in systemic lupus erythematosus?
    • A. Loeliger Prothrombin as co-factor of the circulating anticoagulant in systemic lupus erythematosus? Thromb. Diath. Haemorrh. 3 1959 237 256
    • (1959) Thromb. Diath. Haemorrh. , vol.3 , pp. 237-256
    • Loeliger, A.1
  • 7
    • 0025951058 scopus 로고
    • Lupus anticoagulant IgG's (LA) are not directed to phospholipids only, but to a complex of lipid-bound human prothrombin
    • E.M. Bevers, M. Galli, M. Barbui, P. Comfurius, and R.F.A. Zwaal Lupus anticoagulant IgG's (LA) are not directed to phospholipids only, but to a complex of lipid-bound human prothrombin Thromb. Haemost. 66 1991 629 632
    • (1991) Thromb. Haemost. , vol.66 , pp. 629-632
    • Bevers, E.M.1    Galli, M.2    Barbui, M.3    Comfurius, P.4    Zwaal, R.F.A.5
  • 8
    • 0028022531 scopus 로고
    • Anti-annexin V antibody in systemic lupus erythematosus patients with lupus anticoagulant and/or anticardiolipin antibody
    • J. Matsuda, N. Saitoh, K. Gohchi, M. Gotoh, and M. Tsukamoto Anti-annexin V antibody in systemic lupus erythematosus patients with lupus anticoagulant and/or anticardiolipin antibody Am. J. Hematol. 47 1994 56 58
    • (1994) Am. J. Hematol. , vol.47 , pp. 56-58
    • Matsuda, J.1    Saitoh, N.2    Gohchi, K.3    Gotoh, M.4    Tsukamoto, M.5
  • 9
    • 0030931521 scopus 로고    scopus 로고
    • The epitopes for some antiphospholipid antibodies are adducts of oxidized phospholipid and β2 glycoprotein I (and other proteins)
    • S. Hörkkö, E. Miller, D.W. Branch, W. Palinski, and J.L. Witztum The epitopes for some antiphospholipid antibodies are adducts of oxidized phospholipid and β2 glycoprotein I (and other proteins) Proc. Natl. Acad. Sci. U. S. A. 94 1997 10356 10361
    • (1997) Proc. Natl. Acad. Sci. U. S. A. , vol.94 , pp. 10356-10361
    • Hörkkö, S.1    Miller, E.2    Branch, D.W.3    Palinski, W.4    Witztum, J.L.5
  • 10
    • 0030937274 scopus 로고    scopus 로고
    • Different anticoagulant and immunological properties of anti-prothrombin antibodies in patients with antiphospholipid antibodies
    • M. Galli, G. Beretta, M. Daldossi, E.M. Bevers, and T. Barbui Different anticoagulant and immunological properties of anti-prothrombin antibodies in patients with antiphospholipid antibodies Thromb. Haemost. 77 1997 486 491
    • (1997) Thromb. Haemost. , vol.77 , pp. 486-491
    • Galli, M.1    Beretta, G.2    Daldossi, M.3    Bevers, E.M.4    Barbui, T.5
  • 11
    • 0031790361 scopus 로고    scopus 로고
    • Inhibition of lupus anticoagulant activity by hexagonal phase phosphatidylethanolamine in the presence of prothrombin
    • J. Rauch, M. Tannenbaum, C. Neville, and P.R. Fortin Inhibition of lupus anticoagulant activity by hexagonal phase phosphatidylethanolamine in the presence of prothrombin Thromb. Haemost. 80 1998 936 941
    • (1998) Thromb. Haemost. , vol.80 , pp. 936-941
    • Rauch, J.1    Tannenbaum, M.2    Neville, C.3    Fortin, P.R.4
  • 12
    • 50549207211 scopus 로고
    • Thrombosis in systemic lupus erythematosus despite circulating anticoagulants
    • E.J.W. Bowie, J.H. Thompson, C.A. Pascuzzi, and C.A. Owen Thrombosis in systemic lupus erythematosus despite circulating anticoagulants J. Lab. Clin. Med. 62 1963 416 430
    • (1963) J. Lab. Clin. Med. , vol.62 , pp. 416-430
    • Bowie, E.J.W.1    Thompson, J.H.2    Pascuzzi, C.A.3    Owen, C.A.4
  • 14
    • 0023772539 scopus 로고
    • Anti-prothrombin antibodies and the lupus anticoagulant
    • R.A. Fleck, S.I. Rapaport, and L.V.M. Rao Anti-prothrombin antibodies and the lupus anticoagulant Blood 72 1988 512 519
    • (1988) Blood , vol.72 , pp. 512-519
    • Fleck, R.A.1    Rapaport, S.I.2    Rao, L.V.M.3
  • 15
    • 0028330345 scopus 로고
    • Accelerated in vitro apoptosis of lymphocytes from patients with systemic lupus erythematosus
    • W. Emlen, J. Niebur, and R. Kadera Accelerated in vitro apoptosis of lymphocytes from patients with systemic lupus erythematosus J. Immunol. 152 1994 3685 3692
    • (1994) J. Immunol. , vol.152 , pp. 3685-3692
    • Emlen, W.1    Niebur, J.2    Kadera, R.3
  • 16
    • 0031838606 scopus 로고    scopus 로고
    • Impaired phagocytosis of apoptotic cell material by monocyte-derived macrophages from patients with systemic lupus erythematosus
    • M. Herrmann, R.E. Voll, O.M. Zoller, M. Hagenhofer, B.B. Ponner, and J.R. Kalden Impaired phagocytosis of apoptotic cell material by monocyte-derived macrophages from patients with systemic lupus erythematosus Arthritis Rheum. 41 1998 1241 1250
    • (1998) Arthritis Rheum. , vol.41 , pp. 1241-1250
    • Herrmann, M.1    Voll, R.E.2    Zoller, O.M.3    Hagenhofer, M.4    Ponner, B.B.5    Kalden, J.R.6
  • 17
    • 0033168145 scopus 로고    scopus 로고
    • Immunogenicity of apoptotic cells in vivo: Role of antigen load, antigen-presenting cells, and cytokines
    • A. Ronchetti, P. Rovere, G. Iezzi, G. Galati, S. Heltai, and M.P. Protti Immunogenicity of apoptotic cells in vivo: role of antigen load, antigen-presenting cells, and cytokines J. Immunol. 163 1999 130 136
    • (1999) J. Immunol. , vol.163 , pp. 130-136
    • Ronchetti, A.1    Rovere, P.2    Iezzi, G.3    Galati, G.4    Heltai, S.5    Protti, M.P.6
  • 18
    • 0028288510 scopus 로고
    • Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes
    • L.A. Casciola-Rosen, G. Anhalt, and A. Rosen Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes J. Exp. Med. 179 1994 1317 1330
    • (1994) J. Exp. Med. , vol.179 , pp. 1317-1330
    • Casciola-Rosen, L.A.1    Anhalt, G.2    Rosen, A.3
  • 19
    • 0027999537 scopus 로고
    • Specific cleavage of the 70 kDa protein component of the U1 small nuclear riboprotein is a characteristic biochemical feature of apoptotic cell death
    • L.A. Casciola-Rosen, D.K. Miller, G.J. Anhalt, and A. Rosen Specific cleavage of the 70 kDa protein component of the U1 small nuclear riboprotein is a characteristic biochemical feature of apoptotic cell death J. Biol. Chem. 269 1994 30757 30760
    • (1994) J. Biol. Chem. , vol.269 , pp. 30757-30760
    • Casciola-Rosen, L.A.1    Miller, D.K.2    Anhalt, G.J.3    Rosen, A.4
  • 20
    • 0033588955 scopus 로고    scopus 로고
    • Cleavage by granzyme B is strongly predictive of autoantigen status: Implications for initiation of autoimmunity
    • L.A. Casciola-Rosen, F. Andrade, D. Ulanet, W. Bang Wong, and A. Rosen Cleavage by granzyme B is strongly predictive of autoantigen status: implications for initiation of autoimmunity J. Exp. Med. 190 1999 815 826
    • (1999) J. Exp. Med. , vol.190 , pp. 815-826
    • Casciola-Rosen, L.A.1    Andrade, F.2    Ulanet, D.3    Bang Wong, W.4    Rosen, A.5
  • 21
    • 0030891492 scopus 로고    scopus 로고
    • Proteins phosphorylated during stress-induced apoptosis are common targets for autoantibody production in patients with systemic lupus erythematosus
    • P.J. Utz, M. Hottelet, P.H. Schur, and P. Anderson Proteins phosphorylated during stress-induced apoptosis are common targets for autoantibody production in patients with systemic lupus erythematosus J. Exp. Med. 185 1997 843 854
    • (1997) J. Exp. Med. , vol.185 , pp. 843-854
    • Utz, P.J.1    Hottelet, M.2    Schur, P.H.3    Anderson, P.4
  • 22
    • 0030918572 scopus 로고    scopus 로고
    • Membrane and morphological changes in apoptotic cells regulated by caspase-mediated activation of PAK2
    • T. Rudel, and G.M. Bokoch Membrane and morphological changes in apoptotic cells regulated by caspase-mediated activation of PAK2 Science 276 1997 1571 1574
    • (1997) Science , vol.276 , pp. 1571-1574
    • Rudel, T.1    Bokoch, G.M.2
  • 24
    • 0033732503 scopus 로고    scopus 로고
    • Cardiolipin on the surface of apoptotic cells as a possible trigger for anti-phospholipid antibodies
    • M. Sorice, A. Circella, R. Misasi, V. Pittoni, T. Garofalo, and A. Cirelli Cardiolipin on the surface of apoptotic cells as a possible trigger for anti-phospholipid antibodies Clin. Exp. Immunol. 122 2000 277 284
    • (2000) Clin. Exp. Immunol. , vol.122 , pp. 277-284
    • Sorice, M.1    Circella, A.2    Misasi, R.3    Pittoni, V.4    Garofalo, T.5    Cirelli, A.6
  • 25
    • 0030240765 scopus 로고    scopus 로고
    • Anti-phospholipid autoantibodies bind to apoptotic, but not viable, thymocytes in a β2-glycoprotein I-dependent manner
    • B.E. Price, J. Rauch, M.A. Shia, M.T. Walsh, W. Lieberthal, and H.M. Gilligan Anti-phospholipid autoantibodies bind to apoptotic, but not viable, thymocytes in a β2-glycoprotein I-dependent manner J. Immunol. 157 1996 2201 2208
    • (1996) J. Immunol. , vol.157 , pp. 2201-2208
    • Price, B.E.1    Rauch, J.2    Shia, M.A.3    Walsh, M.T.4    Lieberthal, W.5    Gilligan, H.M.6
  • 26
    • 0032191322 scopus 로고    scopus 로고
    • Induction of anti-phospholipid autoantibodies by β2-glycoprotein I bound to apoptotic thymocytes
    • J.S. Levine, R. Subang, J.S. Koh, and J. Rauch Induction of anti-phospholipid autoantibodies by β2-glycoprotein I bound to apoptotic thymocytes J. Autoimmun. 11 1998 413 424
    • (1998) J. Autoimmun. , vol.11 , pp. 413-424
    • Levine, J.S.1    Subang, R.2    Koh, J.S.3    Rauch, J.4
  • 27
    • 0346666716 scopus 로고    scopus 로고
    • Prothrombin binds to the surface of apoptotic, but not viable, cells and serves as a target of lupus anticoagulant autoantibodies
    • P. D'Agnillo, J.S. Levine, R. Subang, and J. Rauch Prothrombin binds to the surface of apoptotic, but not viable, cells and serves as a target of lupus anticoagulant autoantibodies J. Immunol. 170 2003 3408 3422
    • (2003) J. Immunol. , vol.170 , pp. 3408-3422
    • D'Agnillo, P.1    Levine, J.S.2    Subang, R.3    Rauch, J.4
  • 29
    • 0028210036 scopus 로고
    • Phospholipid-specific conformational changes in human prothrombin upon binding to procoagulant acidic lipid membranes
    • J.R. Wu, and B.R. Lentz Phospholipid-specific conformational changes in human prothrombin upon binding to procoagulant acidic lipid membranes Thromb. Haemost. 71 1994 596 604
    • (1994) Thromb. Haemost. , vol.71 , pp. 596-604
    • Wu, J.R.1    Lentz, B.R.2
  • 30
    • 0033711669 scopus 로고    scopus 로고
    • Association of autoantibodies against the phosphatidylserine-prothrombin complex with manifestations of the antiphospholipid syndrome and with the presence of lupus anticoagulant
    • T. Atsumi, M. Ieko, M.L. Bertolaccini, K. Ichikawa, A. Tsutsumi, and E. Matsuura Association of autoantibodies against the phosphatidylserine- prothrombin complex with manifestations of the antiphospholipid syndrome and with the presence of lupus anticoagulant Arthritis Rheum. 43 2000 1982 1993
    • (2000) Arthritis Rheum. , vol.43 , pp. 1982-1993
    • Atsumi, T.1    Ieko, M.2    Bertolaccini, M.L.3    Ichikawa, K.4    Tsutsumi, A.5    Matsuura, E.6
  • 31
    • 0010392008 scopus 로고
    • Specificity and clinical relevance of lupus anticoagulant
    • P.G. de Groot, and R.H.W.M. Derksen Specificity and clinical relevance of lupus anticoagulant Vessels 1 1995 22 26
    • (1995) Vessels , vol.1 , pp. 22-26
    • De Groot, P.G.1    Derksen, R.H.W.M.2
  • 32
    • 0035873773 scopus 로고    scopus 로고
    • Lupus antibody bivalency is required to enhance prothrombin binding to phospholipid
    • S.L. Field, C.N. Chesterman, Y.-P. Dai, and P.J. Hogg Lupus antibody bivalency is required to enhance prothrombin binding to phospholipid J. Immunol. 166 2001 6118 6125
    • (2001) J. Immunol. , vol.166 , pp. 6118-6125
    • Field, S.L.1    Chesterman, C.N.2    Dai, Y.-P.3    Hogg, P.J.4
  • 33
    • 0029959119 scopus 로고    scopus 로고
    • Mechanism and effects of the binding of lupus anticoagulant IgG and prothrombin to surface phospholipid
    • L.V.M. Rao, A.D. Hoang, and S.I. Rapaport Mechanism and effects of the binding of lupus anticoagulant IgG and prothrombin to surface phospholipid Blood 88 1996 4173 4182
    • (1996) Blood , vol.88 , pp. 4173-4182
    • Rao, L.V.M.1    Hoang, A.D.2    Rapaport, S.I.3
  • 34
    • 0034993220 scopus 로고    scopus 로고
    • Complexes of anti-prothrombin antibodies and prothrombin cause lupus anticoagulant activity by competing with the binding of clotting factors for catalytic phospholipid surfaces
    • M.J.A. Simmelink, D.A. Horbach, R.H.W.M. Derksen, J.C.M. Meijers, E.M. Bevers, and G.M. Willems Complexes of anti-prothrombin antibodies and prothrombin cause lupus anticoagulant activity by competing with the binding of clotting factors for catalytic phospholipid surfaces Br. J. Haematol. 113 2001 621 629
    • (2001) Br. J. Haematol. , vol.113 , pp. 621-629
    • Simmelink, M.J.A.1    Horbach, D.A.2    Derksen, R.H.W.M.3    Meijers, J.C.M.4    Bevers, E.M.5    Willems, G.M.6
  • 35
    • 0033495741 scopus 로고    scopus 로고
    • An IgG antiprothrombin antibody enhances prothrombin binding to damaged endothelial cells and shortens plasma coagulation times
    • Y. Zhao, R. Rumold, M. Zhu, D. Zhou, A.E. Ahmed, and D.T. Le An IgG antiprothrombin antibody enhances prothrombin binding to damaged endothelial cells and shortens plasma coagulation times Arthritis Rheum. 42 1999 2132 2138
    • (1999) Arthritis Rheum. , vol.42 , pp. 2132-2138
    • Zhao, Y.1    Rumold, R.2    Zhu, M.3    Zhou, D.4    Ahmed, A.E.5    Le D., T.6
  • 37
    • 0030610162 scopus 로고    scopus 로고
    • Anti-β2-glycoprotein I (β2GPI) monoclonal antibodies with lupus anticoagulant-like activity enhance the β2GPI binding to phospholipids
    • H. Takeya, T. Mori, E.C. Gabazza, K. Kuroda, H. Deguchi, and E. Matsuura Anti-β2-glycoprotein I (β2GPI) monoclonal antibodies with lupus anticoagulant-like activity enhance the β2GPI binding to phospholipids J. Clin. Invest. 99 1997 2260 2268
    • (1997) J. Clin. Invest. , vol.99 , pp. 2260-2268
    • Takeya, H.1    Mori, T.2    Gabazza, E.C.3    Kuroda, K.4    Deguchi, H.5    Matsuura, E.6
  • 38
    • 0031984075 scopus 로고    scopus 로고
    • Beta-2-glycoprotein I dependent lupus anticoagulants form stable bivalent antibody beta-2-glycoprotein I complexes on phospholipid surfaces
    • J. Arnout, C. Wittevrongel, M. Vanrusselt, M. Hoylaerts, and J. Vermylen Beta-2-glycoprotein I dependent lupus anticoagulants form stable bivalent antibody beta-2-glycoprotein I complexes on phospholipid surfaces Thromb. Haemost. 79 1998 79 86
    • (1998) Thromb. Haemost. , vol.79 , pp. 79-86
    • Arnout, J.1    Wittevrongel, C.2    Vanrusselt, M.3    Hoylaerts, M.4    Vermylen, J.5
  • 42
    • 0029866102 scopus 로고    scopus 로고
    • Surface blebs on apoptotic cells are sites of enhanced procoagulant activity: Implications for coagulation events and antigenic spread in systemic lupus erythematosus
    • L. Casciola-Rosen, A. Rosen, M. Petri, and M. Schlissel Surface blebs on apoptotic cells are sites of enhanced procoagulant activity: implications for coagulation events and antigenic spread in systemic lupus erythematosus Proc. Natl. Acad. Sci. U. S. A. 93 1996 1624 1629
    • (1996) Proc. Natl. Acad. Sci. U. S. A. , vol.93 , pp. 1624-1629
    • Casciola-Rosen, L.1    Rosen, A.2    Petri, M.3    Schlissel, M.4


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