A general life-death selection strategy for dissecting protein functions

Nature Methods

Volumn 6, Issue 11, 2009, Pages 813-816

  Ear, Po Hien ^a   Michnick, Stephen W ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOSINE DEAMINASE; FLUCYTOSINE; GLUTATHIONE TRANSFERASE; RAF PROTEIN; RAS PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SWI4; TRANSCRIPTION FACTOR SWI6; UNCLASSIFIED DRUG;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL COMPARTMENTALIZATION; CELL TYPE; CLONAL VARIATION; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; FUNGAL STRAIN; GENE DISRUPTION; GENE MUTATION; GENETIC COMPLEMENTATION; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MODIFICATION; PROTEIN PROTEIN INTERACTION; REPORTER GENE; SACCHAROMYCES CEREVISIAE; THERMOSTABILITY; TRANSACTIVATION;

CYTOSINE DEAMINASE; GENETIC COMPLEMENTATION TEST; PEPTIDE FRAGMENTS; PROTEIN INTERACTION MAPPING; SACCHAROMYCES CEREVISIAE;

SACCHAROMYCES CEREVISIAE;

EID: 70350704659     PISSN: 15487091     EISSN: 15491676     Source Type: Journal    
DOI: 10.1038/nmeth.1389     Document Type: Article

References (20)

1. Reguly, T. et al. J. Biol. 5, 11 (2006).
2. Pelletier, J.N., Campbell-Valois, F.X. & Michnick, S.W. Proc. Natl. Acad. Sci. USA 95, 12141-12146 (1998).
3. Michnick, S.W., Ear, P.H., Manderson, E.N., Remy, I. & Stefan, E. Nat. Rev. Drug Discov. 6, 569-582 (2007).
4. Mahan, S.D., Ireton, G.C., Knoeber, C., Stoddard, B.L. & Black, M.E. Protein Eng. Des. Sel. 17, 625-633 (2004).
5. Hartzog, P.E., Nicholson, B.P. & McCusker, J.H. Yeast 22, 789-798 (2005).
6. Wei, K. & Huber, B.E. J. Biol. Chem. 271, 3812-3816 (1996).
7. Fang, F., Hoskins, J. & Butler, J.S. Mol. Cell. Biol. 24, 10766-10776 (2004).
8. Korkegian, A., Black, M.E., Baker, D. & Stoddard, B.L. Science 308, 857-860 (2005).
9. Block, C., Janknecht, R., Herrmann, C., Nassar, N. & Wittinghofer, A. Nat. Struct. Biol. 3, 244-251 (1996).
10. Porter, S.W. & West, A.H. Biochim. Biophys. Acta 1748, 138-145 (2005).
11. Bahler, J. Annu. Rev. Genet. 39, 69-94 (2005).
12. Andrews, B.J. & Moore, L.A. Proc. Natl. Acad. Sci. USA 89, 11852-11856 (1992).
13. Sedgwick, S.G. et al. J. Mol. Biol. 281, 763-775 (1998).
14. Remy, I., Wilson, I.A. & Michnick, S.W. Science 283, 990-993 (1999).
15. Tarassov, K. et al. Science 320, 1465-1470 (2008).
16. Pelletier, J.N., Campbell-Valois, F.X. & Michnick, S.W. Proc. Natl. Acad. Sci. USA 95, 12141-12146 (1998).
17. Block, C., Janknecht, R., Herrmann, C., Nassar, N. & Wittinghofer, A. Nat. Struct. Biol. 3, 244-251 (1996).
18. Giaever, G. et al. Nature 418, 387-391 (2002).
19. Rollins, C.T. et al. Proc. Natl. Acad. Sci. USA 97, 7096-7101 (2000).
20. Ralser, M., Goehler, H., Wanker, E.E., Lehrach, H. & Krobitsch, S. Biotechniques 39, 165-166, 168 (2005).