Gossypol induced apoptosis of polymorphonuclear leukocytes and monocytes: Involvement of mitochondrial pathway and reactive oxygen species

Immunopharmacology and Immunotoxicology

Volumn 31, Issue 2, 2009, Pages 320-330

  Barba Barajas, Martha ^a   Hernndez Flores, Georgina ^a   Lerma Daz, Jos M ^a   Ortiz Lazareno, Pablo C ^a   Domnguez Rodrguez, Jorge R ^a   Barba Barajas, Leticia ^a   Celis, Ruth De ^a   Jave Suarez, Luis F ^a   Aguilar Lemarroy, Adriana C ^a   Guevara Barraza, Mario G ^a   Bravo Cuellar, Alejandro ^a,b  

^a INSTITUTO MEXICANO DEL SEGURO SOCIAL   (Mexico)

^b UNIVERSITY OF GUADALAJARA   (Mexico)

Author keywords

Apoptosis; Caspases; Gossypol; Monocyte; Phagocytosis; Polymorphonuclear leukocyte; Reactive oxygen species

Indexed keywords

CASPASE 10; CASPASE 3; CASPASE 7; CASPASE 9 INHIBITOR; GOSSYPOL; PROTEIN BAD; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL XL; PROTEIN MCL 1; PROTEIN P53; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; TROLOX C; 6-HYDROXY-2,5,7,8-TETRAMETHYLCHROMAN-2-CARBOXYLIC ACID; ANTIOXIDANT; CASPASE; CHROMAN DERIVATIVE; CYCLIN D1; MYELOID LEUKEMIA FACTOR 1; PROTEIN BCL 2; TP53 PROTEIN, HUMAN;

ADULT; APOPTOSIS; ARTICLE; CANCER THERAPY; CELL ACTIVITY; CELL VIABILITY; CONTROLLED STUDY; DOSE RESPONSE; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; MONOCYTE; NEUTROPHIL; NORMAL HUMAN; PHAGOCYTE; PHAGOCYTOSIS; PRIORITY JOURNAL; YEAST; BIOSYNTHESIS; DRUG EFFECTS; METABOLISM; YOUNG ADULT;

ADULT; ANTIOXIDANTS; APOPTOSIS; BCL-2 HOMOLOGOUS ANTAGONIST-KILLER PROTEIN; BCL-2-ASSOCIATED X PROTEIN; BCL-ASSOCIATED DEATH PROTEIN; CASPASES; CHROMANS; CYCLIN D1; FEMALE; GOSSYPOL; HUMANS; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; MONOCYTES; MYELOID CELL LEUKEMIA SEQUENCE 1 PROTEIN; NEUTROPHILS; PHAGOCYTOSIS; PROTO-ONCOGENE PROTEINS C-BCL-2; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE; TUMOR SUPPRESSOR PROTEIN P53; YOUNG ADULT;

EID: 70350680559     PISSN: 08923973     EISSN: 15322513     Source Type: Journal    
DOI: 10.1080/08923970902718049     Document Type: Article

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