Suppression of Th1-and Th2-type immune responses in infant mouse spleen after prenatal and postnatal exposure to low-level toluene and peptidoglycan

Inhalation Toxicology

Volumn 21, Issue 9, 2009, Pages 793-802

  Yamamoto, Shoji ^a   Shwe, Tin Tin Win ^a   Yoshida, Yasuhiro ^b   Kunugita, Naoki ^b   Arashidani, Keiichi ^b   Fujimaki, Hidekazu ^a  

^a NATIONAL INSTITUTE FOR ENVIRONMENTAL STUDIES   (Japan)

^b UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

Author keywords

Infant mice; Inhalation exposure; Peptidoglycan; Th1 Th2 immunity; Toluene

Indexed keywords

GAMMA INTERFERON; IMMUNOGLOBULIN E ANTIBODY; IMMUNOGLOBULIN G1 ANTIBODY; IMMUNOGLOBULIN G2A ANTIBODY; INTERLEUKIN 12; INTERLEUKIN 4; INTERLEUKIN 5; MESSENGER RNA; PEPTIDOGLYCAN; TOLUENE; TRANSCRIPTION FACTOR FOXP3; TRANSCRIPTION FACTOR GATA 3; TRANSCRIPTION FACTOR T BET;

ANIMAL EXPERIMENT; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; FEMALE; IMMUNE RESPONSE; IMMUNITY; IMMUNOGLOBULIN BLOOD LEVEL; LITTER SIZE; MOUSE; NONHUMAN; PRENATAL EXPOSURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPLEEN; SPLEEN WEIGHT; TH1 CELL; TH2 CELL;

AIR POLLUTANTS; ANIMALS; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG THERAPY, COMBINATION; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; IMMUNITY, CELLULAR; IMMUNOGLOBULINS; INHALATION EXPOSURE; INTERFERON-GAMMA; LUNG; MALE; MATERNAL EXPOSURE; MICE; MICE, INBRED BALB C; PEPTIDOGLYCAN; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RNA, MESSENGER; SPLEEN; TH1 CELLS; TH2 CELLS; TOLUENE;

MUS;

EID: 70350671483     PISSN: 08958378     EISSN: 10917691     Source Type: Journal    
DOI: 10.1080/08958370902798448     Document Type: Article

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