Understanding drug-excipient compatibility: Oxidation of compound A in a solid dosage form Understanding drug-excipient compatibility Y. Wu et al.

Pharmaceutical Development and Technology

Volumn 14, Issue 5, 2009, Pages 556-564

  Wu, Yongmei ^a   Dali, Mandar ^b   Gupta, Abhishek ^a,c   Raghavan, Krishnaswamy ^a  

^a BRISTOL MYERS SQUIBB   (United States)

^b PTC THERAPEUTICS   (United States)

^c MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Antioxidants; Degradants; Discoloration; Drug excipient compatibility; Free radicals; Maillard reaction; Microcrystalline cellulose; Oxidation; Reactive oxidative species; Solid dosage form

Indexed keywords

BUTYLATED HYDROXYANISOLE; BUTYLCRESOL; EDETIC ACID; EXCIPIENT; GALLIC ACID PROPYL ESTER; HYDROGEN PEROXIDE; MAGNESIUM STEARATE; MICROCRYSTALLINE CELLULOSE; PHENYLALANINE; REACTIVE OXYGEN METABOLITE; STARCH; STARCH GLYCOLATE SODIUM; WATER;

ARTICLE; CAPSULE ENDOSCOPE; COLOR; DRUG DEGRADATION; DRUG DOSAGE FORM; DRUG OXIDATION; DRUG STABILITY; EXCIPIENT COMPATIBILITY; GLYCATION; PRIORITY JOURNAL; SOLID; THERMOSTABILITY;

ANTIOXIDANTS; DRUG INCOMPATIBILITY; DRUG STABILITY; EXCIPIENTS; OXIDATION-REDUCTION; OXYGEN; PHARMACEUTICAL PREPARATIONS; PHENYLALANINE;

EID: 70350656252     PISSN: 10837450     EISSN: 10979867     Source Type: Journal    
DOI: 10.1080/10837450903182140     Document Type: Article

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