In-source fragmentation of very labile peptides in matrix-assisted laser desorption/ionization time-of-flight mass spectrometry

Analytical Chemistry

Volumn 81, Issue 21, 2009, Pages 8986-8992

  Sachon, Emmanuelle ^a,b   Clodic, Gilles ^b   Blasco, Thierry ^b   Jacquot, Yves ^a   Bolbach, Gérard ^a,b  

^a Centre National de la Recherche Scientifique   (France)

^b SORBONNE UNIVERSITÉ   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDE BOND; AXIAL VELOCITY; BASIC CHEMICALS; CRYSTALLIZATION PROCESS; EXTRACTION DELAY; IN-SOURCE DECAYS; ION MASS; MALDI-TOF; MATRIX; MATRIX-ASSISTED LASER DESORPTION/IONIZATION TIME-OF-FLIGHT; MATRIX-ASSISTED LASER DESORPTION/IONIZATION-TIME-OF-FLIGHT MASS SPECTROMETRY; N-TERMINALS; PLUME EXPANSION; POSITIVE ION MODE; PROTON AFFINITY; PROTONATED PEPTIDES;

AMIDES; AMINO ACIDS; DESORPTION; MASS SPECTROMETERS; MASS SPECTROMETRY; PEPTIDES; PROTONS;

AMINES;

AMIDE; ARGININE; PROLINE; PROTON; SYNTHETIC PEPTIDE;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; COLLISIONALLY ACTIVATED DISSOCIATION; CORRELATION ANALYSIS; CRYSTALLIZATION; EXTRACTION; FRAGMENTATION REACTION; IONIZATION; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; PLUME; PROTEIN DETERMINATION; PROTEIN MOTIF; PROTEIN STRUCTURE; SURVIVAL; VELOCITY;

AMINO ACID SEQUENCE; CHROMATOGRAPHY, LIQUID; NANOTECHNOLOGY; PEPTIDES; PROLINE; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 70350639277     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac901449d     Document Type: Article

References (27)

1. Fenn, J.; Mann, M.; Meng, C.; Wong, S.; Whitehouse, C. Science 1989, 246, 64-71.
2. Karas, M.; Bachmann, D.; Bahr, U.; Hillenkamp, F. Int. J. Mass Spectrom. 1987, 78, 53-68.
3. Karas, M.; Hillenkamp, F. Anal. Chem. 1988, 60, 2299-2301.
4. Yu, W.; Vath, J. E.; Huberty, M. C.; Martin, S. A. Anal. Chem. 1993, 65, 3015-3023.
5. Gorman, J. J.; Ferguson, B. L.; Nguyen, T. B. Rapid Commun. Mass Spectrom. 1996, 10, 529-536.
6. Skribanek, Z.; Mezo, G.; Mak, M.; Hudecz, F. J. Pept. Sci. 2002, 8, 398-406.
7. Maux, D.; Enjalbal, C.; Martinez, J.; Aubagnac, J. L. Rapid Commun. Mass Spectrom. 2002, 16, 1470-1475.
8. Schulz, E.; Karas, M.; Rosu, F.; Gabelica, V. J. Am. Soc. Mass Spectrom. 2006, 17, 1005-1013.
9. Kapitan, J.; Gallo, D.; Goasdoué, N.; Niçaise, M.; Desmadril, M.; Hecht, L.; Leclercq, G.; Barron, L. D.; Jacquot, Y. J. Pept. Sci. 2009, 15, 455-464.
10. Gobom, J.; Nordhoff, E.; Mirgorodskaya, E.; Ekman, R.; Roepstorff, P. J. Mass Spectrom. 1999, 34, 105-116.
11. Paizs, B.; Suhai, S. Mass Spectrom. Rev. 2005, 24, 508-548.
12. Gu, C.; Tsaprailis, G.; Breci, L.; Wysocki, V. H. Anal. Chem. 2000, 72, 5804-5813.
13. Tsaprailis, G.; Nair, H.; Somogyi, A.; Wysocki, V. H.; Zhong, W.; Futrell, J. H.; Summerfield, S. G.; Gaskell, S. J. J. Am. Chem. Soc. 1999, 121, 5142-5154.
14. Cheng, C.; Gross, M. L. Mass Spectrom. Rev. 2000, 19, 398-420.
15. Fernandez Ocana, M.; Jarvis, J.; Parker, R.; Bramley, P. M.; Halket, J. M.; Patel, R. K.; Neubert, H. Proteomics 2005, 5, 1209-1216.
16. Breci, L. A.; Tabb, D. L.; Yates, J. R., III; Wysocki, V. H. Anal. Chem. 2003, 75, 1963-1971.
17. Nair, H.; Wysocki, V. H. Int. J. Mass Spectrom. Ion Processes 1998, 174, 95-100.
18. Cooks, R. G.; Wong, P. S. H. Acc. Chem. Res. 1998, 31, 379-386.
19. Mirza, S. P.; Raju, N. P.; Vairamani, M. J. Am. Soc. Mass Spectrom. 2004, 15, 431-435.
20. Glückmann, M.; Karas, M. J. Mass Spectrom. 1999, 34, 467-477.
21. Karas, M.; Bahr, U.; Fournier, I.; Glückmann, M.; Pfenninger, A. Int. J. Mass Spectrom. 2003, 226, 239-248.
22. Spengler, B.; Kirsch, D. Int. J. Mass Spectrom. 2003, 226, 71-83.
23. Juhasz, P.; Vestal, M. L.; Martin, S. A. J. Am. Soc. Mass Spectrom. 1997, 8, 209-217.
24. Brown, R. S.; Carr, B. L.; Lennon, J. J. J. Am. Soc. Mass Spectrom. 1996.
25. Brown, R. S.; Feng, J.; Reiber, D. C. Int. J. Mass Spectrom. 1997, 169/170, 1-18.
26. Kocher, T.; Engstrom, A.; Zubarev, R. A. Anal. Chem. 2005, 77, 172-177.
27. Piszkiewicz, D.; Landon, M.; Smith, E. L. Biochem. Biophys. Res. Commun. 1970, 40, 1173-1178.