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Volumn 9, Issue 10, 2009, Pages 1405-1411

Radiochemotherapy in the elderly with lung cancer

Author keywords

Adenocarcinoma histology; Early concurrent hyperfractionated radiotherapy; Elderly patients; Elective nodal irradiation; Limited stage small cell lung cancer; Lung cancer; Lung cancer in women; Non small cell lung cancer; Prophylactic cranial irradiation; Radiochemotherapy

Indexed keywords

ANTINEOPLASTIC AGENT; BEVACIZUMAB; CARBOPLATIN; CYCLOPHOSPHAMIDE; DOXORUBICIN; ETOPOSIDE; FLUORODEOXYGLUCOSE F 18; PLATINUM COMPLEX; VINCRISTINE;

EID: 70350604481     PISSN: 14737140     EISSN: 17448328     Source Type: Journal    
DOI: 10.1586/ERA.09.110     Document Type: Review
Times cited : (8)

References (49)
  • 1
    • 33645976782 scopus 로고    scopus 로고
    • Radiation therapy alone in elderly with early stage non-small cell lung cancer
    • San José S, Arnaiz MD, Lucas A et al. Radiation therapy alone in elderly with early stage non-small cell lung cancer. Lung Cancer 52, 149-154 (2006).
    • (2006) Lung Cancer , vol.52 , pp. 149-154
    • San José, S.1    Arnaiz, M.D.2    Lucas, A.3
  • 2
    • 0034564180 scopus 로고    scopus 로고
    • Recursive partitioning analysis of 1999 Radiation Therapy Oncology Group (RTOG) patients with locally-advanced non-small-cell lung cancer (LA-NSCLC): Identification of five groups with different survival
    • Werner-Wasik M, Scott C, Cox JD et al. Recursive partitioning analysis of 1999 Radiation Therapy Oncology Group (RTOG) patients with locally-advanced non-small-cell lung cancer (LA-NSCLC): identification of five groups with different survival. Int. J. Radiat. Oncol. Biol. Phys. 48, 1475-1482 (2000).
    • (2000) Int. J. Radiat. Oncol. Biol. Phys. , vol.48 , pp. 1475-1482
    • Werner-Wasik, M.1    Scott, C.2    Cox, J.D.3
  • 3
    • 0346236869 scopus 로고    scopus 로고
    • Long-term benefit is observed in a Phase III comparison of sequential vs concurrent chemoradiation for patients with unresected stage III NSCLC: RTOG 9410
    • Abstract 2499
    • Curran WJ, Scott CB, Langer CJ et al. Long-term benefit is observed in a Phase III comparison of sequential vs concurrent chemoradiation for patients with unresected stage III NSCLC: RTOG 9410. Proc. Am. Soc. Clin. Oncol. 22, 621(2003) (Abstract 2499).
    • (2003) Proc. Am. Soc. Clin. Oncol. , vol.22 , pp. 621
    • Curran, W.J.1    Scott, C.B.2    Langer, C.J.3
  • 4
    • 0141465153 scopus 로고    scopus 로고
    • The outcome of combined-modality therapy for stage III non-small-cell lung cancer in the elderly
    • Schild SE, Stella PJ, Séller SM et al. The outcome of combined-modality therapy for stage III non-small-cell lung cancer in the elderly. J. Clin. Oncol. 21, 3201-3206 (2003).
    • (2003) J. Clin. Oncol. , vol.21 , pp. 3201-3206
    • Schild, S.E.1    Stella, P.J.2    Séller, S.M.3
  • 5
    • 0036140654 scopus 로고    scopus 로고
    • Therapy choices among older patients with lung carcinoma: An evaluation of two trials of the Cancer and Leukemia Group B
    • Rocha Lima CM, Herdon JE 2nd, Kosty M et al. Therapy choices among older patients with lung carcinoma: an evaluation of two trials of the Cancer and Leukemia Group B. Cancer 94, 181-187 (2002).
    • (2002) Cancer , vol.94 , pp. 181-187
    • Rocha Lima, C.M.1    Herdon II, J.E.2    Kosty, M.3
  • 8
    • 33745009238 scopus 로고    scopus 로고
    • Age is independent of comorbidity influencing patient selection for combined modality therapy for treatment of stage III nonsmall cell lung cancer (NSCLC)
    • DOI 10.1097/01.coc.0000217824.20290.ab, PII 0000042120060600000007
    • Firat S, Pleister A, Virad RW, Gore E. Age is independent of comorbidity influencing patient selection for combined modality therapy for treatment of stage non-small cell lung cancer (NSCLC) Am. J. Clin. Oncol. 29, 252-257 (2006). (Pubitemid 44270933)
    • (2006) American Journal of Clinical Oncology: Cancer Clinical Trials , vol.29 , Issue.3 , pp. 252-257
    • Firat, S.1    Pleister, A.2    Byhardt, R.W.3    Gore, E.4
  • 9
    • 37349033598 scopus 로고    scopus 로고
    • Impact of comorbidity and age on the outcome of patients with inoperable NSCLC treated with concurrent chemoradiotherapy
    • DOI 10.1016/j.rmed.2007.09.009, PII S0954611107003964
    • Semarau S, Klautke G, Virchow JC, Kundt G, Fietkau R. Impact of comorbidity and age on the outcome of patients with inoperable NSCLC treated with concurrent chemoradiotherapy. Respir. Med. 102, 210-218 (2008). (Pubitemid 350296909)
    • (2008) Respiratory Medicine , vol.102 , Issue.2 , pp. 210-218
    • Semrau, S.1    Klautke, G.2    Virchow, J.C.3    Kundt, G.4    Fietkau, R.5
  • 10
    • 34249988209 scopus 로고    scopus 로고
    • A randomized study of involved-field irradiation versus elective nodal irradiation in combination with concurrent chemotherapy for inoperable stage III nonsmall cell lung cancer
    • DOI 10.1097/01.coc.0000256691.27796.24, PII 0000042120070600000005
    • Yuan S, Sun X, Li M et al. A randomized study of involved-field irradiation versus elective nodal irradiation in combination with concurrent chemotherapy for inoperable stage III non-small cell lung cancer. Am. J. Clin. Oncol. 30, 239-244 (2007). • Landmark study influencing involved-field irradiation versus elective nodal irradiation in radiochemotherapy for stage III non-small-cell lung cancer (NSCLC). (Pubitemid 46884142)
    • (2007) American Journal of Clinical Oncology: Cancer Clinical Trials , vol.30 , Issue.3 , pp. 239-244
    • Yuan, S.1    Sun, X.2    Li, M.3    Yu, J.4    Ren, R.5    Yu, Y.6    Li, J.7    Liu, X.8    Wang, R.9    Li, B.10    Kong, L.11    Yin, Y.12
  • 11
    • 51449108879 scopus 로고    scopus 로고
    • Report from the Internacional Atomic Energy Agency (IAEA) consultant's meeting on elective nodal irradiation in lung cancer: Non-small cell lung cancer (NSCLC)
    • Landmark study influencing elective nodal irradiation in NSCLC
    • Belbederlos J, Kepta L, Kong FM, Martel MK, Videtic G, Jeremic B. Report from the Internacional Atomic Energy Agency (IAEA) consultant's meeting on elective nodal irradiation in lung cancer: non-small cell lung cancer (NSCLC). Int. J. Radiat. Oncol. Biol. Phys. 72, 335-342 (2008). • Landmark study influencing elective nodal irradiation in NSCLC.
    • (2008) Int. J. Radiat. Oncol. Biol. Phys. , vol.72 , pp. 335-342
    • Belbederlos, J.1    Kepta, L.2    Kong, F.M.3    Martel, M.K.4    Videtic, G.5    Jeremic, B.6
  • 14
    • 1942478492 scopus 로고    scopus 로고
    • Prediction of radiation pneumonitis by dose-volume histogram parameters in lung cancer - A systematic review
    • Rodrigues G, Lock M, D'Souza D et al. Prediction of radiation pneumonitis by dose-volume histogram parameters in lung cancer - a systematic review. Radiother. Oncol. 71, 127-138 (2005).
    • (2005) Radiother. Oncol. , vol.71 , pp. 127-138
    • Rodrigues, G.1    Lock, M.2    D'Souza, D.3
  • 15
  • 16
    • 33750603100 scopus 로고    scopus 로고
    • Changing epidemiology of small-cell lung cancer in the United States over the last 30 years: Analysis of the surveillance, epidemiologic, and end results database
    • DOI 10.1200/JCO.2005.04.4859
    • Ramaswamy R, Page N, Morgensztern D et al. Changing epidemiology of small-cell lung cancer in the United States over the last 30 years; analysis of the surveillance, epidemiology, and end results database. J. Clin. Oncol. 24, 4539-4544 (2005). • Landmark study about the changing epidemiology of small-cell lung cancer (SCLC). (Pubitemid 46630948)
    • (2006) Journal of Clinical Oncology , vol.24 , Issue.28 , pp. 4539-4544
    • Govindan, R.1    Page, N.2    Morgensztern, D.3    Read, W.4    Tierney, R.5    Vlahiotis, A.6    Spitznagel, E.L.7    Piccirillo, J.8
  • 17
    • 0026482388 scopus 로고
    • A meta-analysis of thoracic radiotherapy for small-cell lung cancer
    • Landmark study influencing standard combined treatment of limited-disease (LD)-SCLC
    • Pignon JP, Arriagada R, Ihde DC et al. A meta-analysis of thoracic radiotherapy for small-cell lung cancer. N. Engl. J. Med. 327, 1618-1624 (1992). • Landmark study influencing standard combined treatment of limited-disease (LD)-SCLC.
    • (1992) N. Engl. J. Med. , vol.327 , pp. 1618-1624
    • Pignon, J.P.1    Arriagada, R.2    Ihde, D.C.3
  • 18
    • 33644530368 scopus 로고    scopus 로고
    • Timing of concurrent radiotherapy and chemotherapy in limited-disease small-cell lung cancer: 'Meta-analysis of meta-analyses'
    • Landmark editorial influencing standard combined treatment of LD-SCLC
    • Jeremic B. Timing of concurrent radiotherapy and chemotherapy in limited-disease small-cell lung cancer: 'meta-analysis of meta-analyses'. Int. J. Radiat. Oncol. Biol. Phys. 64, 981-982 (2006). • Landmark editorial influencing standard combined treatment of LD-SCLC.
    • (2006) Int. J. Radiat. Oncol. Biol. Phys. , vol.64 , pp. 981-982
    • Jeremic, B.1
  • 20
    • 0141465153 scopus 로고    scopus 로고
    • The outcome of combined-modality therapy for stage III small cell lung cancer in the elderly
    • Schild SE, Stella PJ ,Geyer SM et al. The outcome of combined-modality therapy for stage III small cell lung cancer in the elderly. J. Clin. Oncol. 21, 3201-3206 (2003).
    • (2003) J. Clin. Oncol. , vol.21 , pp. 3201-3206
    • Schild, S.E.1    Stella, P.J.2    Geyer, S.M.3
  • 21
    • 0034327927 scopus 로고    scopus 로고
    • Similar outcome of elderly patients in Intergroup trial 0096: Cisplatin, etoposide, and thoracic radiotherapy administered once or twice daily in limited stage small cell lung carcinoma
    • Landmark study influencing standard radiochemotherapy in elderly LD-SCLC
    • Yuen AR, Zou G, Turrisi AT et al. Similar outcome of elderly patients in Intergroup trial 0096: cisplatin, etoposide, and thoracic radiotherapy administered once or twice daily in limited stage small cell lung carcinoma. Cancer 89, 1953-1960 (2000). • Landmark study influencing standard radiochemotherapy in elderly LD-SCLC.
    • (2000) Cancer , vol.89 , pp. 1953-1960
    • Yuen, A.R.1    Zou, G.2    Turrisi, A.T.3
  • 22
    • 34748903521 scopus 로고    scopus 로고
    • Limited-stage small cell lung cancer: The current status of combined-modality therapy
    • Socinski MA, Bogart JA. Limited-stage small cell lung cancer: the current status of combined-modality therapy. J. Clin. Oncol. 25, 4137-4145 (2007).
    • (2007) J. Clin. Oncol. , vol.25 , pp. 4137-4145
    • Socinski, M.A.1    Bogart, J.A.2
  • 24
    • 0037376515 scopus 로고    scopus 로고
    • Do age and comorbidity impact treatment allocation and outcomes in limited stage small-cell lung cancer? A community-based population analysis
    • Ludbrook JJ, Truong PT, MacNeil MV et al. Do age and comorbidity impact treatment allocation and outcomes in limited stage small-cell lung cancer? A community-based population analysis. Int. J. Radiat. Oncol. Biol. Phys. 55, 1321-1330 (2003).
    • (2003) Int. J. Radiat. Oncol. Biol. Phys. , vol.55 , pp. 1321-1330
    • Ludbrook, J.J.1    Truong, P.T.2    MacNeil, M.V.3
  • 25
    • 34548613456 scopus 로고    scopus 로고
    • Randomized Phase III trial of carboplatin plus etoposide vs split doses of cisplatin (P) plus etoposide (E) in elderly or poor-risk patients with extensive disease small cell lung cancer (ED-SCLC): JCOG9702
    • Okamoto H, Watanabe K, Kunikane H et al. Randomized Phase III trial of carboplatin plus etoposide vs split doses of cisplatin (P) plus etoposide (E) in elderly or poor-risk patients with extensive disease small cell lung cancer (ED-SCLC): JCOG9702. Proc. Am. Soc. Clin. Oncol. 23, S623 (2005).
    • (2005) Proc. Am. Soc. Clin. Oncol. , vol.23
    • Okamoto, H.1    Watanabe, K.2    Kunikane, H.3
  • 26
    • 0035425262 scopus 로고    scopus 로고
    • Randomized phase II study of cyclophosphamide, doxorubicin, and vincristine compared with single-agent carboplatin in patients with poor prognosis small cell lung carcinoma
    • DOI 10.1002/1097-0142(20010801)92:3<601::AID-CNCR1360>3.0.CO;2-K
    • White SC, Lorigan P, Middleton MR et al. Randomised Phase II study of cyclophosphamide, doxorubicin and vincristine compared with single agent carboplatin in patients with poor prognosis small cell lung cancer. Cancer 92, 601-608 (2001). (Pubitemid 32735196)
    • (2001) Cancer , vol.92 , Issue.3 , pp. 601-608
    • White, S.C.1    Lorigan, P.2    Middleton Heather Anderson, M.R.3    Valle, J.4    Summers, Y.5    Burt, P.A.6    Arance, A.7    Stout, R.8    Thatcher, N.9
  • 27
    • 0032031656 scopus 로고    scopus 로고
    • Carboplatin, etoposide, and accelerated hyperfractionated radiotherapy for elderly patients with limited small cell lung carcinoma: A phase II study
    • DOI 10.1002/(SICI)1097-0142(19980301)82:5<836::AID-CNCR6>3.0.CO;2-H
    • Jeremic B, Shibamoto Y, Acimovic L et al. Carboplatin, etoposide, and accelerated hyperfractionated radiotherapy for elderly patients with limited small cell lung carcinoma: a Phase II study. Cancer 82, 836-841 (1998). • Landmark study influencing radiochemotherapy in elderly LD-SCLC. (Pubitemid 28104161)
    • (1998) Cancer , vol.82 , Issue.5 , pp. 836-841
    • Jeremic, B.1    Shibamoto, Y.2    Acimovic, L.3    Milisavljevic, S.4
  • 28
    • 0031803819 scopus 로고    scopus 로고
    • New combination of the old drugs for elderly patients with small-cell lung cancer: A Phase II study of the PAVE regimen
    • Landmark study influencing radiochemotherapy in elderly LD-SCLC
    • Westeel V, Murray N, Gelmon K et al. New combination of the old drugs for elderly patients with small-cell lung cancer: a Phase II study of the PAVE regimen. J. Clin. Oncol. 16, 1940-1947 (1998). • Landmark study influencing radiochemotherapy in elderly LD-SCLC.
    • (1998) J. Clin. Oncol. , vol.16 , pp. 1940-1947
    • Westeel, V.1    Murray, N.2    Gelmon, K.3
  • 29
    • 27944463193 scopus 로고    scopus 로고
    • Critical review of PET-CT for radiotherapy planning in lung cancer
    • DOI 10.1016/j.critrevonc.2005.05.001, PII S1040842805001174
    • Senan S, De Ruysscher D. Critical review of PET-CT for radiotherapy planning in lung cancer. Crit. Rev. Oncol. Hematol. 56, 345-351 (2005). (Pubitemid 41677616)
    • (2005) Critical Reviews in Oncology/Hematology , vol.56 , Issue.3 , pp. 345-351
    • Senan, S.1    De Ruysscher, D.2
  • 30
    • 51449108879 scopus 로고    scopus 로고
    • Report from the International Atomic Energy Agency (IAEA) Consultants meeting on elective nodal irradiation in lung cancer: Small-cell lung cancer (SCLC)
    • Landmark study influencing elective nodal irradiation in SCLC
    • Videtic G, Belderbos J, Kong F-M, Kepka L, Martel MK, Jeremic B. Report from the International Atomic Energy Agency (IAEA) Consultants meeting on elective nodal irradiation in lung cancer: small-cell lung cancer (SCLC). Int. J. Radiat. Oncol. Biol. Phys. 72, 327-334 (2008). • Landmark study influencing elective nodal irradiation in SCLC.
    • (2008) Int. J. Radiat. Oncol. Biol. Phys. , vol.72 , pp. 327-334
    • Videtic, G.1    Belderbos, J.2    Kong, F.-M.3    Kepka, L.4    Martel, M.K.5    Jeremic, B.6
  • 35
    • 0031424159 scopus 로고    scopus 로고
    • Prophylactic cranial irradiation is indicated following complete response to induction therapy in small cell lung cancer: Results of a multicentre randomised trial
    • United Kingdom Coordinating Committee for Cancer Research (UKCCCR) and the European Organization for Research and treatment of Cancer (EORTC)
    • Gregor A, Cull A, Stephens RJ et al. Prophylactic cranial irradiation is indicated following complete response to induction therapy in small cell lung cancer: results of a multicentre randomised trial. United Kingdom Coordinating Committee for Cancer Research (UKCCCR) and the European Organization for Research and treatment of Cancer (EORTC). Eur. J. Cancer 33, 1752-1758 (1997).
    • (1997) Eur. J. Cancer , vol.33 , pp. 1752-1758
    • Gregor, A.1    Cull, A.2    Stephens, R.J.3
  • 36
    • 38749137376 scopus 로고    scopus 로고
    • Neurocognitive function in patients with small cell lung cancer: Effect of prophylactic cranial irradiation
    • Grosshans DR, Meyers CA, Allen PK et al. Neurocognitive function in patients with small cell lung cancer: effect of prophylactic cranial irradiation. Cancer 112, 589-595 (2008).
    • (2008) Cancer , vol.112 , pp. 589-595
    • Grosshans, D.R.1    Meyers, C.A.2    Allen, P.K.3
  • 38
    • 16544371710 scopus 로고    scopus 로고
    • Enrollment of elderly patients in clinical trials for cancer drug registration: A 7-year experience by the US Food and Drug Administration
    • DOI 10.1200/JCO.2004.02.175
    • Talarico L, Chen G, Pazdur R. Enrollment of elderly patients in clinical trials for cancer drug registration: a 7-year experience by the US Food and Drug Administration. J. Clin. Oncol. 22, 4626-4631 (2004). (Pubitemid 41185131)
    • (2004) Journal of Clinical Oncology , vol.22 , Issue.22 , pp. 4626-4631
    • Talarico, L.1    Chen, G.2    Pazdur, R.3
  • 39
    • 0642335269 scopus 로고    scopus 로고
    • National institutes of health consensus development conference statement geriatric assessment methods for clinical decision-making
    • Solomon D, Brummel-Smith K, Burgess L et al. National institutes of health consensus development conference statement geriatric assessment methods for clinical decision-making. J. Am. Geriatr. Soc. 51, 1490-1494 (1998).
    • (1998) J. Am. Geriatr. Soc. , vol.51 , pp. 1490-1494
    • Solomon, D.1    Brummel-Smith, K.2    Burgess, L.3
  • 40
    • 0034010518 scopus 로고    scopus 로고
    • Measuring comorbidity in older cancer patients
    • DOI 10.1016/S0959-8049(99)00319-6, PII S0959804999003196
    • Extermann M. Measuring comorbidity in older cancer patients. Eur. J. Cancer 36, 453-471 (2000). (Pubitemid 30136223)
    • (2000) European Journal of Cancer , vol.36 , Issue.4 , pp. 453-471
    • Extermann, M.1
  • 41
    • 37649004819 scopus 로고    scopus 로고
    • Lung cancer in elderly patients: An analysis of the surveillance, epidemiology, and end results database
    • Owonikoko TK, Ragin CC, Belani CP et al. Lung cancer in elderly patients: an analysis of the surveillance, epidemiology, and end results database. J. Clin. Oncol. 25, 5570-5577 (2007).
    • (2007) J. Clin. Oncol. , vol.25 , pp. 5570-5577
    • Owonikoko, T.K.1    Ragin, C.C.2    Belani, C.P.3
  • 42
    • 58149132633 scopus 로고    scopus 로고
    • Locally advanced non-small cell lung cancer: The past, present, and future
    • Govindan R, Bogart J, Vokes EE. Locally advanced non-small cell lung cancer: the past, present, and future. J. Thorac. Oncol. 3, 917-928 (2008).
    • (2008) J. Thorac. Oncol. , vol.3 , pp. 917-928
    • Govindan, R.1    Bogart, J.2    Vokes, E.E.3
  • 43
    • 33244473038 scopus 로고    scopus 로고
    • A Phase I dose-escalating study of combination permetexed-based chemotherapy and concomitant radiotherapy for locally advanced or metastatic non-small cell lung or esophageal cancer
    • Abstract 7062
    • Seiwert TY, Connell PP, Mauer AM et al. A Phase I dose-escalating study of combination permetexed-based chemotherapy and concomitant radiotherapy for locally advanced or metastatic non-small cell lung or esophageal cancer. ASCO 23(16S), (2005) (Abstract 7062).
    • (2005) ASCO , vol.23 , Issue.16 S
    • Seiwert, T.Y.1    Connell, P.P.2    Mauer, A.M.3
  • 45
    • 0032794019 scopus 로고    scopus 로고
    • The benefit of treatment intensification is age and histology-dependent in patients with locally advanced non-small cell lung cancer: A quality-adjusted survival ana lysis of Radiation Therapy Oncology Group (RTOG) chemoradiation studies
    • Movsas B, Scott C, Sause W et al. The benefit of treatment intensification is age and histology-dependent in patients with locally advanced non-small cell lung cancer: a quality-adjusted survival ana lysis of Radiation Therapy Oncology Group (RTOG) chemoradiation studies. Int. J. Radiat. Oncol. Biol. Phys. 45, 1143-1149 (1999).
    • (1999) Int. J. Radiat. Oncol. Biol. Phys. , vol.45 , pp. 1143-1149
    • Movsas, B.1    Scott, C.2    Sause, W.3
  • 46
    • 0034564180 scopus 로고    scopus 로고
    • Recursive partitioning ana lysis of 1999 Radiation Therapy Oncology Group (RTOG) patients with locally-advanced non-small-cell lung cancer (LA-NSCLC): Identification of five groups with different survival
    • Werner-Wasik M, Scott C, Cox JD et al. Recursive partitioning ana lysis of 1999 Radiation Therapy Oncology Group (RTOG) patients with locally-advanced non-small-cell lung cancer (LA-NSCLC): identification of five groups with different survival. Int. J. Radiat. Oncol. Biol. Phys. 48, 1475-1482.
    • Int. J. Radiat. Oncol. Biol. Phys. , vol.48 , pp. 1475-1482
    • Werner-Wasik, M.1    Scott, C.2    Cox, J.D.3
  • 47
    • 0007726820 scopus 로고    scopus 로고
    • Effect of advanced age on outcome in Radiation Therapy Oncology Group studies of locally advanced NSCLC
    • Abstract 340
    • Langer C, Scott C, Byharddt R et al. Effect of advanced age on outcome in Radiation Therapy Oncology Group studies of locally advanced NSCLC. Lung Cancer 29, 104 (2000) (Abstract 340).
    • (2000) Lung Cancer , vol.29 , pp. 104
    • Langer, C.1    Scott, C.2    Byharddt, R.3


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