Concurrent chemoradiotherapy for limited-disease small cell lung cancer in elderly patients aged 75 years or older

Japanese Journal of Clinical Oncology

Volumn 37, Issue 3, 2007, Pages 181-185

  Shimizu, Toshio ^a,b   Sekine, Ikuo ^a   Sumi, Minako ^a   Ito, Yoshinori ^a   Yamada, Kazuhiko ^a   Nokihara, Hiroshi ^a   Yamamoto, Noboru ^a   Kunitoh, Hideo ^a   Ohe, Yuichiro ^a   Tamura, Tomohide ^a  

^a NATIONAL CANCER CENTER HOSPITAL   (Japan)

^b KINDAI UNIVERSITY NARA HOSPITAL   (Japan)

Author keywords

Chemotherapy; Elderly; Radiotherapy; Small cell lung cancer

Indexed keywords

ANTINEOPLASTIC AGENT; CARBOPLATIN; CISPLATIN; ETOPOSIDE; GRANULOCYTE COLONY STIMULATING FACTOR;

AGED; ANOREXIA; ARTICLE; BLOOD TOXICITY; BONE MARROW SUPPRESSION; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER SURVIVAL; CAUSE OF DEATH; CLINICAL ARTICLE; DEMOGRAPHY; DISEASE FREE SURVIVAL; DOSIMETRY; DRUG DOSE REDUCTION; DRUG EFFICACY; DRUG SAFETY; DRUG WITHDRAWAL; ERYTHROCYTE TRANSFUSION; ESOPHAGITIS; FEBRILE NEUTROPENIA; FEMALE; FUNCTIONAL ASSESSMENT; HUMAN; LEUKOPENIA; LUNG SMALL CELL CANCER; MALE; MULTIPLE CYCLE TREATMENT; NEUTROPENIA; PNEUMONIA; RADIATION PNEUMONIA; RETROSPECTIVE STUDY; SURVIVAL TIME; THROMBOCYTE TRANSFUSION; THROMBOCYTOPENIA; TREATMENT RESPONSE;

AGE FACTORS; AGED; AGED, 80 AND OVER; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CARCINOMA, SMALL CELL; COMBINED MODALITY THERAPY; HUMANS; LUNG NEOPLASMS; RADIOTHERAPY; RETROSPECTIVE STUDIES; SURVIVAL RATE; TREATMENT OUTCOME;

EID: 34447632874     PISSN: 03682811     EISSN: 14653621     Source Type: Journal    
DOI: 10.1093/jjco/hym005     Document Type: Article

References (13)

1. Sekine I, Yamamoto N, Kunitoh H, Ohe Y, Tamura T, Kodama T, et al. Treatment of small cell lung cancer in the elderly based on a critical literature review of clinical trials. Cancer Treat Rev 2004;30:359-68.
2. Takada M, Fukuoka M, Kawahara M, Sugiura T, Yokoyama A, Yokota S, et al. Phase III study of concurrent versus sequential thoracic radiotherapy in combination with cisplatin and etoposide for limited-stage small-cell lung cancer: Results of the Japan Clinical Oncology Group Study 9104. J Clin Oncol 2002;20:3054-60.
3. Turrisi AT, 3rd, Kim K, Blum R, Sause WT, Livingston RB, Komaki R, et al. Twice-daily compared with once-daily thoracic radiotherapy in limited small-cell lung cancer treated concurrently with cisplatin and etoposide. N Engl J Med 1999;340:265-71.
4. Sekine I, Fukuda H, Kunitoh H, Saijo N. Cancer chemotherapy in the elderly. Jpn J Clin Oncol 1998;28:463-73.
5. Yuen AR, Zou G, Turrisi AT, Sause W, Komaki R, Wagner H, et al. Similar outcome of elderly patients in intergroup trial 0096: Cisplatin, etoposide, and thoracic radiotherapy administered once or twice daily in limited stage small cell lung carcinoma. Cancer 2000;89:1953-60.
6. Siu LL, Shepherd FA, Murray N, Feld R, Pater J, Zee B. Influence of age on the treatment of limited-stage small-cell lung cancer. J Clin Oncol 1996;14:821-8.
7. Quon H, Shepherd FA, Payne DG, Coy P, Murray N, Feld R, et al. The influence of age on the delivery, tolerance, and efficacy of thoracic irradiation in the combined modality treatment of limited stage small cell lung cancer. Int J Radiat Oncol Biol Phys 1999;43:39-45.
8. Japan Clinical Oncology Group. Common Terminology Criteria for Adverse Events v3.0 Japanese edition. Available at: http://www.jcog.jp/SHIRYOU/ fra_ma_guidetop.htm 2005.
9. World Health Organization. Handbook for reporting results of cancer treatment. Geneva: WHO Offset Publication No. 48, 1979.
10. Okamoto H, Watanabe K, Kunikane H, Yokoyama A, Kudoh S, Ishizuka N, et al. Randomized phase III trial of carboplatin(C) plus etoposide (E) vs. split doses of cisplatin (P) plus etoposide (E) in elderly or poor-risk patients with extensive disease small cell lung cancer (ED-SCLC): JCOG9702. Proc Am Soc Clin Oncol 2005;23:623s.
11. Pignon JP, Arriagada R, Ihde DC, Johnson DH, Perry MC, Souhami RL, et al. A meta-analysis of thoracic radiotherapy for small-cell lung cancer. N Engl J Med 1992;327:1618-24.
12. Jeremic B, Shibamoto Y, Acimovic L, Milisavljevic S. Carboplatin, etoposide, and accelerated hyperfractionated radiotherapy for elderly patients with limited small cell lung carcinoma: A phase II study. Cancer 1998;82:836-41.
13. Westeel V, Murray N, Gelmon K, Shah A, Sheehan F, McKenzie M, et al. New combination of the old drugs for elderly patients with small-cell lung cancer: A phase II study of the PAVE regimen. J Clin Oncol 1998;16:1940-7.