-
1
-
-
0020321767
-
Novel proteinaceous infectious particles cause scrapie
-
10.1126/science.6801762 1:CAS:528:DyaL38XhsFyqtro%3D 6801762
-
SB Prusiner 1982 Novel proteinaceous infectious particles cause scrapie Science 216 136 144 10.1126/science.6801762 1:CAS:528:DyaL38XhsFyqtro%3D 6801762
-
(1982)
Science
, vol.216
, pp. 136-144
-
-
Prusiner, S.B.1
-
3
-
-
0025910229
-
Molecular biology of prion diseases
-
10.1126/science.1675487 1:CAS:528:DyaK3MXksVKqsbo%3D 1675487
-
SB Prusiner 1991 Molecular biology of prion diseases Science 252 1515 1522 10.1126/science.1675487 1:CAS:528:DyaK3MXksVKqsbo%3D 1675487
-
(1991)
Science
, vol.252
, pp. 1515-1522
-
-
Prusiner, S.B.1
-
4
-
-
50649122531
-
Molecular interaction between prion protein and GFAP both in native and recombinant forms in vitro
-
10.1007/s00430-007-0071-0 1:CAS:528:DC%2BD1cXhtVekt7nM 18087720
-
CF Dong XF Wang X Wang S Shi GR Wang B Shan R An XL Li BY Zhang J Han XP Dong 2008 Molecular interaction between prion protein and GFAP both in native and recombinant forms in vitro Med Microbiol Immunol 197 361 368 10.1007/s00430-007-0071-0 1:CAS:528:DC%2BD1cXhtVekt7nM 18087720
-
(2008)
Med Microbiol Immunol
, vol.197
, pp. 361-368
-
-
Dong, C.F.1
Wang, X.F.2
Wang, X.3
Shi, S.4
Wang, G.R.5
Shan, B.6
An, R.7
Li, X.L.8
Zhang, B.Y.9
Han, J.10
Dong, X.P.11
-
5
-
-
0032509499
-
Copper stimulates endocytosis of the prion protein
-
DOI 10.1074/jbc.273.50.33107
-
PC Pauly DA Harris 1998 Copper stimulates endocytosis of the prion protein J Biol Chem 273 33107 33110 10.1074/jbc.273.50.33107 1:CAS:528:DyaK1MXjtQ%3D%3D 9837873 (Pubitemid 29005676)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.50
, pp. 33107-33110
-
-
Pauly, P.C.1
Harris, D.A.2
-
6
-
-
0037180530
-
Creutzfeldt-Jakob disease associated with a deletion of two repeats in the prion protein gene
-
1:CAS:528:DC%2BD38XosVCmtr4%3D 12451210
-
S Capellari P Parchi BD Wolff J Campbell R Atkinson DM Posey RB Petersen P Gambetti 2002 Creutzfeldt-Jakob disease associated with a deletion of two repeats in the prion protein gene Neurology 59 1628 1630 1:CAS:528: DC%2BD38XosVCmtr4%3D 12451210
-
(2002)
Neurology
, vol.59
, pp. 1628-1630
-
-
Capellari, S.1
Parchi, P.2
Wolff, B.D.3
Campbell, J.4
Atkinson, R.5
Posey, D.M.6
Petersen, R.B.7
Gambetti, P.8
-
7
-
-
0025885702
-
Transmissible familial Creutzfeldt-Jakob disease associated with five, seven, and eight extra octapeptide coding repeats in the PRNP gene
-
10.1073/pnas.88.23.10926 1:CAS:528:DyaK38XotFCnug%3D%3D 1683708
-
LG Goldfarb P Brown WR McCombie D Goldgaber GD Swergold PR Wills L Cervenakova H Baron CJ Gibbs DC Gajdusek 1991 Transmissible familial Creutzfeldt-Jakob disease associated with five, seven, and eight extra octapeptide coding repeats in the PRNP gene Proc Natl Acad Sci USA 88 10926 10930 10.1073/pnas.88.23.10926 1:CAS:528:DyaK38XotFCnug%3D%3D 1683708
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 10926-10930
-
-
Goldfarb, L.G.1
Brown, P.2
McCombie, W.R.3
Goldgaber, D.4
Swergold, G.D.5
Wills, P.R.6
Cervenakova, L.7
Baron, H.8
Gibbs, C.J.9
Gajdusek, D.C.10
-
8
-
-
0035943060
-
Two-octapeptide repeat deletion of prion protein associated with rapidly progressive dementia
-
1:STN:280:DC%2BD38%2Fis1ahuw%3D%3D 11468331
-
JA Beck S Mead TA Campbell A Dickinson DP Wientjens EA Croes CM Van Duijn J Collinge 2001 Two-octapeptide repeat deletion of prion protein associated with rapidly progressive dementia Neurology 57 354 356 1:STN:280: DC%2BD38%2Fis1ahuw%3D%3D 11468331
-
(2001)
Neurology
, vol.57
, pp. 354-356
-
-
Beck, J.A.1
Mead, S.2
Campbell, T.A.3
Dickinson, A.4
Wientjens, D.P.5
Croes, E.A.6
Van Duijn, C.M.7
Collinge, J.8
-
9
-
-
34249850125
-
Elevated manganese levels in blood and central nervous system occur before onset of clinical signs in scrapie and bovine spongiform encephalopathy
-
DOI 10.2527/jas.2006-714
-
S Hesketh J Sassoon R Knight J Hopkins DR Brown 2007 Elevated manganese levels in blood and central nervous system occur before onset of clinical signs in scrapie and bovine spongiform encephalopathy J Anim Sci 85 1596 1609 10.2527/jas.2006-714 1:CAS:528:DC%2BD2sXls1antbw%3D 17296770 (Pubitemid 46861507)
-
(2007)
Journal of Animal Science
, vol.85
, Issue.6
, pp. 1596-1609
-
-
Hesketh, S.1
Sassoon, J.2
Knight, R.3
Hopkins, J.4
Brown, D.R.5
-
10
-
-
0031444217
-
B lymphocytes and neuroinvasion
-
DOI 10.1038/37733
-
DR Brown K Quin JW Herms A Madlung J Manson R Stroime PE Fraser TA Kruck A Von Bohlen W Schulz-Schaeffer A Giese D Westaway H Kretzschmar 1997 The cellular prion protein binds copper in vivo Nature 390 684 687 10.1038/37733 1:CAS:528:DyaK1cXhtVWhtg%3D%3D 9414160 (Pubitemid 28016346)
-
(1997)
Nature
, vol.390
, Issue.6661
, pp. 662-663
-
-
Brown, P.1
-
11
-
-
0034654304
-
Consequences of manganese replacement of copper for prion protein function and proteinase resistance
-
10.1093/emboj/19.6.1180 1:CAS:528:DC%2BD3cXit1Gms7s%3D 10716918
-
DR Brown F Hafiz LL Glassmith BS Wong IM Jones C Clive SJ Haswell 2000 Consequences of manganese replacement of copper for prion protein function and proteinase resistance EMBO J 19 1180 1186 10.1093/emboj/19.6.1180 1:CAS:528:DC%2BD3cXit1Gms7s%3D 10716918
-
(2000)
EMBO J
, vol.19
, pp. 1180-1186
-
-
Brown, D.R.1
Hafiz, F.2
Glassmith, L.L.3
Wong, B.S.4
Jones, I.M.5
Clive, C.6
Haswell, S.J.7
-
12
-
-
33846858381
-
Creutzfeldt-Jakob disease in a Chinese patient with a novel seven extra-repeat insertion in PRNP [5]
-
DOI 10.1136/jnnp.2006.09433
-
XF Wang YJ Guo BY Zhang WQ Zhao JM Gao YZ Wan F Li J Han DX Wang XP Dong 2007 Creutzfeldt-Jakob disease in a Chinese patient with a novel seven extra-repeat insertion in PRNP J Neurol Neurosurg Psychiatry 78 201 203 10.1136/jnnp.2006.09433 1:STN:280:DC%2BD2s%2Fjt1OlsA%3D%3D 17229753 (Pubitemid 46220227)
-
(2007)
Journal of Neurology, Neurosurgery and Psychiatry
, vol.78
, Issue.2
, pp. 201-203
-
-
Wang, X.F.1
Guo, Y.J.2
Zhang, B.Y.3
Zhao, W.Q.4
Gao, J.M.5
Wan, Y.Z.6
Li, F.7
Han, J.8
Wang, D.X.9
Dong, X.P.10
-
13
-
-
0032479890
-
The importance of the disulfide bond in prion protein conversion
-
1:CAS:528:DyaK1cXlvVClsbk%3D 9721914
-
LM Herrmann B Caughey 1998 The importance of the disulfide bond in prion protein conversion Neuroreport 9 2457 2461 1:CAS:528:DyaK1cXlvVClsbk%3D 9721914
-
(1998)
Neuroreport
, vol.9
, pp. 2457-2461
-
-
Herrmann, L.M.1
Caughey, B.2
-
14
-
-
38349061552
-
The N-terminus of PrP is responsible for interacting with tubulin and fCJD related PrP mutants possess stronger inhibitive effect on microtubule assembly in vitro
-
10.1016/j.abb.2007.11.007 1:CAS:528:DC%2BD1cXptlWiug%3D%3D 18037369
-
CF Dong S Shi XF Wang R An P Li JM Chen X Wang GR Wang B Shan BY Zhang J Han XP Dong 2008 The N-terminus of PrP is responsible for interacting with tubulin and fCJD related PrP mutants possess stronger inhibitive effect on microtubule assembly in vitro Arch Biochem Biophys 470 83 92 10.1016/j.abb.2007.11.007 1:CAS:528:DC%2BD1cXptlWiug%3D%3D 18037369
-
(2008)
Arch Biochem Biophys
, vol.470
, pp. 83-92
-
-
Dong, C.F.1
Shi, S.2
Wang, X.F.3
An, R.4
Li, P.5
Chen, J.M.6
Wang, X.7
Wang, G.R.8
Shan, B.9
Zhang, B.Y.10
Han, J.11
Dong, X.P.12
-
15
-
-
0027190754
-
Evaluation of secondary structure of proteins from UV circular dichroism spectra using an unsupervised learning neural network
-
10.1093/protein/6.4.383 1:CAS:528:DyaK3sXkvFSmsbg%3D 8332596
-
MA Andrade P Chacon JJ Merelo F Moran 1993 Evaluation of secondary structure of proteins from UV circular dichroism spectra using an unsupervised learning neural network Protein Eng 6 383 390 10.1093/protein/6.4.383 1:CAS:528:DyaK3sXkvFSmsbg%3D 8332596
-
(1993)
Protein Eng
, vol.6
, pp. 383-390
-
-
Andrade, M.A.1
Chacon, P.2
Merelo, J.J.3
Moran, F.4
-
16
-
-
40849087729
-
Copper-induced structural changes in the ovine prion protein are influenced by a polymorphism at codon 112
-
1:CAS:528:DC%2BD1cXjtlChu74%3D 18280261
-
S Yang AM Thackray TJ Fitzmaurice R Bujdoso 2008 Copper-induced structural changes in the ovine prion protein are influenced by a polymorphism at codon 112 Biochim Biophys Acta 1784 683 692 1:CAS:528:DC%2BD1cXjtlChu74%3D 18280261
-
(2008)
Biochim Biophys Acta
, vol.1784
, pp. 683-692
-
-
Yang, S.1
Thackray, A.M.2
Fitzmaurice, T.J.3
Bujdoso, R.4
-
17
-
-
0037083888
-
Metal imbalance and compromised antioxidant function are early changes in prion disease
-
DOI 10.1042/0264-6021:3620253
-
AM Thackray R Knight SJ Haswell R Bujdoso DR Brown 2002 Metal imbalance and compromised antioxidant function are early changes in prion disease Biochem J 362 253 258 10.1042/0264-6021:3620253 1:CAS:528:DC%2BD38XhvVemur4%3D 11829763 (Pubitemid 34174483)
-
(2002)
Biochemical Journal
, vol.362
, Issue.1
, pp. 253-258
-
-
Thackray, A.M.1
Knight, R.2
Haswell, S.J.3
Bujdoso, R.4
Brown, D.R.5
-
18
-
-
0034764599
-
Oxidative impairment in scrapie-infected mice is associated with brain metals perturbations and altered antioxidant activities
-
DOI 10.1046/j.1471-4159.2001.00625.x
-
BS Wong DR Brown T Pan M Whiteman T Liu X Bu R Li P Gambetti J Olesik R Rubenstein MS Sy 2001 Oxidative impairment in scrapie-infected mice is associated with brain metals perturbations and altered antioxidant activities J Neurochem 79 689 698 10.1046/j.1471-4159.2001.00625.x 1:CAS:528: DC%2BD3MXotlShur4%3D 11701772 (Pubitemid 33029942)
-
(2001)
Journal of Neurochemistry
, vol.79
, Issue.3
, pp. 689-698
-
-
Wong, B.-S.1
Brown, D.R.2
Pan, T.3
Whiteman, M.4
Liu, T.5
Bu, X.6
Li, R.7
Gambetti, P.8
Olesik, J.9
Rubenstein, R.10
Sy, M.-S.11
-
19
-
-
59049096855
-
A patient with Creutzfeldt-Jakob disease with an insertion of 7 octa-repeats in the PRNP gene: Molecular characteristics and clinical features
-
10.1097/MAJ.0b013e3181643e50 19092329
-
YJ Guo XF Wang J Han BY Zhang WQ Zhao Q Shi YZ Wan C Gao JM Li DX Wang XP Dong 2008 A patient with Creutzfeldt-Jakob disease with an insertion of 7 octa-repeats in the PRNP gene: molecular characteristics and clinical features Am J Med Sci 336 6 519 523 10.1097/MAJ.0b013e3181643e50 19092329
-
(2008)
Am J Med Sci
, vol.336
, Issue.6
, pp. 519-523
-
-
Guo, Y.J.1
Wang, X.F.2
Han, J.3
Zhang, B.Y.4
Zhao, W.Q.5
Shi, Q.6
Wan, Y.Z.7
Gao, C.8
Li, J.M.9
Wang, D.X.10
Dong, X.P.11
-
20
-
-
34748836985
-
Sc by Western blot assay based on streptomycin sulphate precipitation
-
DOI 10.1111/j.1863-2378.2007.01062.x
-
CF Dong YX Huang R An JM Chen XF Wang B Shan YJ Lei J Han BY Zhang XP Dong 2007 Sensitive detection of PrPSc by Western blot assay based on streptomycin sulphate precipitation Zoonoses Public Health 54 328 336 10.1111/j.1863-2378.2007.01062.x 1:CAS:528:DC%2BD2sXht1yit7fI 17894644 (Pubitemid 47485663)
-
(2007)
Zoonoses and Public Health
, vol.54
, Issue.8
, pp. 328-336
-
-
Dong, C.-F.1
Huang, Y.-X.2
An, R.3
Chen, J.-M.4
Wang, X.-F.5
Shan, B.6
Lei, Y.-J.7
Han, L.8
Zhang, B.-Y.9
Han, J.10
Dong, X.-P.11
-
21
-
-
0029027854
-
Truncated forms of the human prion protein in normal brain and in prion disease
-
10.1074/jbc.270.32.19173 1:CAS:528:DyaK2MXnsVOisL4%3D 7642585
-
SG Chen DB Teplow P Parchi JK Teller P Gambetti L Autilio-Gambetti 1995 Truncated forms of the human prion protein in normal brain and in prion disease J Biol Chem 270 19173 19180 10.1074/jbc.270.32.19173 1:CAS:528: DyaK2MXnsVOisL4%3D 7642585
-
(1995)
J Biol Chem
, vol.270
, pp. 19173-19180
-
-
Chen, S.G.1
Teplow, D.B.2
Parchi, P.3
Teller, J.K.4
Gambetti, P.5
Autilio-Gambetti, L.6
-
22
-
-
70350613474
-
Analyses of some biochemical features of the recombinant human PrP proteins with mutations in the octapeptide repeats region within N-terminus
-
1:CAS:528:DC%2BD28XovFequ7g%3D (in Chinese)
-
JM Gao YZ Wan XF Wang J Han L Chen W Zhou XP Dong 2005 Analyses of some biochemical features of the recombinant human PrP proteins with mutations in the octapeptide repeats region within N-terminus Chin J Virol 21 376 383 1:CAS:528:DC%2BD28XovFequ7g%3D (in Chinese)
-
(2005)
Chin J Virol
, vol.21
, pp. 376-383
-
-
Gao, J.M.1
Wan, Y.Z.2
Wang, X.F.3
Han, J.4
Chen, L.5
Zhou, W.6
Dong, X.P.7
-
23
-
-
0029054937
-
The N-terminal domain of a glycolipid-anchored prion protein is essential for its endocytosis via clathrin-coated pits
-
10.1074/jbc.270.24.14793 1:CAS:528:DyaK2MXmsVShsr4%3D 7782345
-
SL Shyng KL Moulder A Lesko DA Harris 1995 The N-terminal domain of a glycolipid-anchored prion protein is essential for its endocytosis via clathrin-coated pits J Biol Chem 270 14793 14800 10.1074/jbc.270.24.14793 1:CAS:528:DyaK2MXmsVShsr4%3D 7782345
-
(1995)
J Biol Chem
, vol.270
, pp. 14793-14800
-
-
Shyng, S.L.1
Moulder, K.L.2
Lesko, A.3
Harris, D.A.4
-
24
-
-
0038399786
-
Cooperative binding of dominant-negative prion protein to kringle domains
-
DOI 10.1016/S0022-2836(03)00342-5
-
C Ryou SB Prusiner G Legname 2003 Cooperative binding of dominant- negative prion protein to kringle domains J Mol Biol 329 323 333 10.1016/S0022-2836(03)00342-5 1:CAS:528:DC%2BD3sXjvFeru70%3D 12758079 (Pubitemid 36561587)
-
(2003)
Journal of Molecular Biology
, vol.329
, Issue.2
, pp. 323-333
-
-
Ryou, C.1
Prusiner, S.B.2
Legname, G.3
-
25
-
-
0028820863
-
Prion disease associated with a novel nine octapeptide repeat insertion in the PRNP gene
-
10.1016/0169-328X(95)00175-R 1:CAS:528:DyaK2MXptlCrtrw%3D 8750875
-
S Krasemann I Zerr T Weber S Poser H Kretzschmar G Hunsmann W Bodemer 1995 Prion disease associated with a novel nine octapeptide repeat insertion in the PRNP gene Brain Res Mol Brain Res 34 173 176 10.1016/0169-328X(95)00175-R 1:CAS:528:DyaK2MXptlCrtrw%3D 8750875
-
(1995)
Brain Res Mol Brain Res
, vol.34
, pp. 173-176
-
-
Krasemann, S.1
Zerr, I.2
Weber, T.3
Poser, S.4
Kretzschmar, H.5
Hunsmann, G.6
Bodemer, W.7
-
26
-
-
20444454586
-
Mammalian prion protein suppresses bax-induced cell death in yeast
-
DOI 10.1074/jbc.C500058200
-
A Li DA Harris 2005 Mammalian prion protein suppresses Bax-induced cell death in yeast J Biol Chem 280 17430 17434 10.1074/jbc.C500058200 1:CAS:528:DC%2BD2MXjsFOnsr4%3D 15753097 (Pubitemid 41389214)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.17
, pp. 17430-17434
-
-
Li, A.1
Harris, D.A.2
-
27
-
-
0034625069
-
Accumulation of protease-resistant prion protein (PrP) and apoptosis of cerebellar granule cells in transgenic mice expressing a PrP insertional mutation
-
DOI 10.1073/pnas.97.10.5574
-
R Chiesa B Drisaldi E Quaglio A Migheli P Piccardo B Ghetti DA Harris 2000 Accumulation of protease-resistant prion protein (PrP) and apoptosis of cerebellar granule cells in transgenic mice expressing a PrP insertional mutation Proc Natl Acad Sci USA 97 5574 5579 10.1073/pnas.97.10.5574 1:CAS:528:DC%2BD3cXjsVWmsLo%3D 10805813 (Pubitemid 30313760)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.10
, pp. 5574-5579
-
-
Chiesa, R.1
Drisaldi, B.2
Quaglio, E.3
Migheli, A.4
Piccardo, P.5
Ghetti, B.6
Harris, D.A.7
-
28
-
-
45149107529
-
Manganese binding to the prion protein
-
10.1074/jbc.M709820200 1:CAS:528:DC%2BD1cXltlGrs7k%3D 18332141
-
MW Brazier P Davies E Player F Marken JH Viles DR Brown 2008 Manganese binding to the prion protein J Biol Chem 283 12831 12839 10.1074/jbc.M709820200 1:CAS:528:DC%2BD1cXltlGrs7k%3D 18332141
-
(2008)
J Biol Chem
, vol.283
, pp. 12831-12839
-
-
Brazier, M.W.1
Davies, P.2
Player, E.3
Marken, F.4
Viles, J.H.5
Brown, D.R.6
|