Adiponectin identified as an agonist for PAQR3/RKTG using a yeast-based assay system PAQR3 as a potential adiponectin receptor I. Garitaonandia et al.

Journal of Receptors and Signal Transduction

Volumn 29, Issue 1, 2009, Pages 67-73

  Garitaonandia, Ibon ^b   Smith, Jessica L ^a   Kupchak, Brian R ^a   Lyons, Thomas J ^a  

^a University of Florida ^*  (United States)

^b NONE

Author keywords

Adiponectin receptor; AdipoR1; PAQR3; RKTG; Yeast

Indexed keywords

ADIPONECTIN; ADIPONECTIN RECEPTOR; ADIPONECTIN RECEPTOR 1; ADIPONECTIN RECEPTOR 2; MEMBRANE RECEPTOR; PAQR3 RECEPTOR; PAQR4 RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; PROTEIN EXPRESSION; PROTEIN FUNCTION; YEAST;

EID: 70350576221     PISSN: 10799893     EISSN: 15324281     Source Type: Journal    
DOI: 10.1080/10799890902729456     Document Type: Article

References (22)

1. Tang YT, Hu T, Arterburn M, Boyle B, Bright JM, Emtage PC, Funk WD. PAQR proteins: A novel membrane receptor family defined by an ancient 7-transmembrane pass motif. J Mol Evol (2005), 61(3), 372-380.
2. Smith JL, Kupchak BR, Garitaonandia I, Hoang LK, Maina AS, Regalla LM, Lyons TJ. Heterologous expression of human mPRalpha, mPRbeta and mPRgamma in yeast confirms their ability to function as membrane progesterone receptors. Steroids (2008), doi:10.1016/j.steroids.2008.05.003, 73 (11), 1160-1173.
3. Yamauchi T, Kamon J, Ito Y, Tsuchida A, Yokomizo T, Kita S, Sugiyama T, Miyagishi M, Hara K, Tsunoda M, Murakami K, Ohteki T, Uchida S, Takekawa S, Waki H, Tsuno NH, Shibata Y, Terauchi Y, Froguel P, Tobe K, Koyasu S, Taira K, Kitamura T, Shimizu T, Nagai R, Kadowaki T. Cloning of adiponectin receptors that mediate antidiabetic metabolic effects. Nature (2003), 423(6941), 762-769.
4. Zhu Y, Bond J, Thomas P. Identification, classification, and partial characterization of genes in humans and other vertebrates homologous to a fish membrane progestin receptor. Proc Natl Acad Sci U S A (2003), 100(5), 2237-2242.
5. Brauer AU, Nitsch R, Savaskan NE. Identification of macrophage/ microglia activation factor (MAF) associated with late endosomes/lysosomes in microglial cells. FEBS Lett (2004), 563(1-3), 41-48.
6. Rehli M, Krause SW, Schwarzfischer L, Kreutz M, Andreesen R. Molecular cloning of a novel macrophage maturation-associated transcript encoding a protein with several potentialtransmembrane domains. Biochem Biophys Res Commun (1995), 217(2), 661-667.
7. Fernandes MS, Brosens JJ, Gellersen, B. Honey, we need to talk about the membrane progestin receptors. Steroids (2008), 73(9-10), 942-952.
8. Barb D, Williams CJ, Neuwirth AK, Mantzoros CS. Adiponectin in relation to malignancies: A review of existing basic research and clinical evidence. Am J Clin Nutr (2007), 86(3), s858-866.
9. 2p overexpression. Biochim Biophys Acta (2007), 1773(7), 1124-1132.
10. Fan F, Feng L, He J, Wang X, Jiang X, Zhang Y, Wang Z, Chen Y. RKTG sequesters B-Raf to the Golgi apparatus and inhibits the proliferation and tumorigenicity of human malignant melanoma cells. Carcinogenesis (2008).
11. Jansen G, Wu C, Schade B, Thomas DY, Whiteway M. Drag&Drop cloning in yeast. Gene (2005), 34443-34451
12. Melcher K. A modular set of prokaryotic and eukaryotic expression vectors. Anal Biochem (2000), 277(1), 109-120.
13. Lyons TJ, Villa NY, Regalla LM, Kupchak BR, Vagstad A, Eide DJ. Metalloregulation of yeast membrane steroid receptor homologs. Proc Natl Acad Sci U S A (2004), 101(15), 5506-5511.
14. Yamaguchi-Iwai Y, Stearman R, Dancis A, Klausner RD. Ironregulated DNA binding by the AFT1 protein controls the iron regulon in yeast. Embo J (1996), 15(13), 3377-3384.
15. Eide D, Guarente L. Increased dosage of a transcriptional activator gene enhances iron-limited growth of Saccharomyces cerevisiae. J Gen Microbiol (1992), 138(2), 347-354.
16. Holcomb CL, Etcheverry T, Schekman R. Isolation of secretory vesicles from Saccharomyces cerevisiae. Anal Biochem (1987), 166(2), 328-334.
17. Thompson JD, Gibson TJ, Plewniak F, Jeanmougin F, Higgins DG. The CLUSTAL-Xwindows interface: Flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res (1997), 25(24), 4876-4882.
18. Page RD. TreeView: An application to display phylogenetic trees on personal computers. Comput Appl Biosci (1996), 12(4), 357-358.
19. Narasimhan ML, Coca MA, Jin J, Yamauchi T, Ito Y, Kadowaki T, Kim KK, Pardo JM, Damsz B, Hasegawa PM, Yun DJ, Bressan RA. Osmotin is a homolog of mammalian adiponectin and controls apoptosis in yeast through a homolog of mammalian adiponectin receptor. Mol Cell (2005), 17(2), 171-180.
20. Singh NK, Bracker CA, Hasegawa PM, Handa AK, Buckel S, Hermodson MA, Pfankoch E, Regnier FE, Bressan RA. Characterization of osmotin: A thaumatin-like protein associated with osmotic adaptation in plant cells. Plant Physiol (1987), 85(2), 529-536.
21. Lara-Castro C, Luo N, Wallace P, Klein RL, Garvey WT. Adiponectin multimeric complexes and the metabolic syndrome trait cluster. Diabetes (2006), 55(1), 249-259.
22. Thomas P, Pang Y, Dong J, Groenen P, Kelder J, de Vlieg J, Zhu Y, Tubbs C. Steroid and G protein binding characteristics of the sea trout and human progestin membrane receptor alpha subtypes and their evolutionary origins. Endocrinology (2007), 148(2), 705-718.