The epoxygenases CYP2J2 activates the nuclear receptor PPARα in vitro and in vivo

PLoS ONE

Volumn 4, Issue 10, 2009, Pages

  Wray, Jessica A ^a   Sugden, Mary C ^b   Zeldin, Darryl C ^c   Greenwood, Gemma K ^b   Samsuddin, Salma ^b   Miller Degraff, Laura ^c   Bradbury, J Alyce ^c   Holness, Mark J ^b   Warner, Timothy D ^a   Bishop Bailey, David ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^b QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^c NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 2J2; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PYRUVATE DEHYDROGENASE; PYRUVATE DEHYDROGENASE KINASE 4; UNCLASSIFIED DRUG; ARACHIDONATE EPOXYGENASE; CYTOCHROME P450; LIGAND; LIPID; PROTEIN KINASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENE ACTIVATION; GENE EXPRESSION; GENE TARGETING; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIPID METABOLISM; MOUSE; NONHUMAN; PROTEIN EXPRESSION; REPORTER GENE; ANIMAL; C57BL MOUSE; CHEMISTRY; DOSE RESPONSE; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; INFLAMMATION; METABOLISM; MOUSE MUTANT; PHYSIOLOGY; TRANSGENIC MOUSE;

MUS MUSCULUS;

ANIMALS; CYTOCHROME P-450 ENZYME SYSTEM; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION; HUMANS; INFLAMMATION; LIGANDS; LIPIDS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; PPAR ALPHA; PROTEIN KINASES; TRANSCRIPTION, GENETIC;

EID: 70350540660     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0007421     Document Type: Article

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