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Volumn 104, Issue 4, 2009, Pages 752-765

The effect of bcl-2, YAMA, and XIAP over-expression on apoptosis and adenovirus production in HEK293 cell line

Author keywords

Adenovirus; Apoptosis; Bcl 2; HEK293; XIAP; YAMA

Indexed keywords

ADENOVIRUS; APOPTOSIS; BCL-2; HEK293; XIAP; YAMA;

EID: 70350516573     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.22439     Document Type: Article
Times cited : (8)

References (48)
  • 2
    • 0025462723 scopus 로고
    • Electron microscopy of hybridoma cells with special regard to monoclonal antibody production
    • Al-Rubeai M, Mills D, Emery AN. 1990. Electron microscopy of hybridoma cells with special regard to monoclonal antibody production. Cytotechnology 4(1):13-28.
    • (1990) Cytotechnology , vol.4 , Issue.1 , pp. 13-28
    • Al-Rubeai, M.1    Mills, D.2    Emery, A.N.3
  • 3
    • 0032212605 scopus 로고    scopus 로고
    • Vaccinia virus-induced apoptosis in immature B lymphocytes: Role of cellular Bcl-2
    • DOI 10.1016/S0168-1702(98)00105-1, PII S0168170298001051
    • Baixeras E, Cebrian A, Albar JP, Salas J, Martnez-A C, Vinuela E, Revilla Y. 1998. Vaccinia virus-induced apoptosis in immature B lymphocytes: Role of cellular Bcl-2. Virus Res 58:107-113. (Pubitemid 28546727)
    • (1998) Virus Research , vol.58 , Issue.1-2 , pp. 107-113
    • Baixeras, E.1    Cebrian, A.2    Albar, J.P.3    Salas, J.4    Martinez-A, C.5    Vinuela, E.6    Revilla, Y.7
  • 4
    • 0037032091 scopus 로고    scopus 로고
    • Adenovirus infection induces microglial activation: Involvement of mitogen-activated protein kinase pathways
    • DOI 10.1016/S0006-8993(02)02953-0, PII S0006899302029530
    • Bhat NR, Fan F. 2002. Adenovirus infection induces microglial activation: Involvement of mitogen-activated protein kinase pathways. Brain Res 948:93-101. (Pubitemid 35283765)
    • (2002) Brain Research , vol.948 , Issue.1-2 , pp. 93-101
    • Bhat, N.R.1    Fan, F.2
  • 5
    • 0032537765 scopus 로고    scopus 로고
    • A comparison of intensive cell culture bioreactors operating with Hybridomas modified for inhibited apoptotic response
    • DOI 10.1016/S0168-1656(98)00064-9, PII S0168165698000649
    • Bierau H, Perani A, Al-Rubeai M, Emery AN. 1998. A comparison of intensive cell culture bioreactors operating with Hybridomas modified for inhibited apoptotic response. J Biotechnol 62:195-207. (Pubitemid 28352343)
    • (1998) Journal of Biotechnology , vol.62 , Issue.3 , pp. 195-207
    • Bierau, H.1    Perani, A.2    Al-Rubeai, M.3    Emery, A.N.4
  • 6
    • 0035956240 scopus 로고    scopus 로고
    • The role of adenovirus E4orf4 protein in viral replication and cell killing
    • DOI 10.1038/sj/onc/1204862
    • Branton PE, Roopchand DE. 2001. The role of adenovirus E4orf4 protein in viral replication and cell killing. Oncogene 20:7855-7865. (Pubitemid 33135312)
    • (2001) Oncogene , vol.20 , Issue.54 REV. ISS. 7 , pp. 7855-7865
    • Branton, P.E.1    Roopchand, D.E.2
  • 7
    • 0032565431 scopus 로고    scopus 로고
    • Inhibition of ICE-like proteases inhibits apoptosis and increases virus production during adenovirus infection
    • DOI 10.1006/viro.1998.9077
    • Chiou S-K, White E. 1998. Inhibition of ICE-like proteases inhibits apoptosis and increases virus production during adenovirus infection. Virology 244:108-118. (Pubitemid 28384131)
    • (1998) Virology , vol.244 , Issue.1 , pp. 108-118
    • Chiou, S.-K.1    White, E.2
  • 9
    • 0034722379 scopus 로고    scopus 로고
    • Caspases disrupt the nuclear-cytoplasmic barrier
    • Falerio L, Lazebnik Y. 2000. Caspases disrupt the nuclear-cytoplasmic barrier. J Cell Biol 151:951-959.
    • (2000) J Cell Biol , vol.151 , pp. 951-959
    • Falerio, L.1    Lazebnik, Y.2
  • 10
    • 0028979478 scopus 로고
    • Starvation-induced programmed cell death of hybridoma cells: Prevention by amino acid mixtures
    • Franek F. 1995. Starvation-induced programmed cell death of hybridoma cells: Prevention by amino acid mixtures. Biotechnol Bioeng 45:86-90.
    • (1995) Biotechnol Bioeng , vol.45 , pp. 86-90
    • Franek, F.1
  • 11
    • 0027031095 scopus 로고
    • Fragmented DNA and apoptotic bodies document the programmed way of cell death in hybridoma cultures
    • Franek F, Vomanstek T, Dolnikova J. 1992. Fragmented DNA and apoptotic bodies document the programmed way of cell death in hybridoma cultures. Cytotechnology 9:117-123.
    • (1992) Cytotechnology , vol.9 , pp. 117-123
    • Franek, F.1    Vomanstek, T.2    Dolnikova, J.3
  • 12
    • 0030512945 scopus 로고    scopus 로고
    • Overexpression of bcl-2 improved survival of COS-1 cells and enhanced transient protein production
    • DOI 10.1016/S0922-338X(97)81258-5
    • Fujita T, Terada S, Ueda H, Susuki E. 1996. Overexpression of bcl-2 improved survival of COS-1 cells and enhanced transient protein production. J Ferment Bioeng 82(6):589-591. (Pubitemid 27044271)
    • (1996) Journal of Fermentation and Bioengineering , vol.82 , Issue.6 , pp. 589-591
    • Fujita, T.1    Terada, S.2    Ueda, H.3    Suzuki, E.4
  • 13
    • 0030625699 scopus 로고    scopus 로고
    • Virus-induced apoptosis
    • Hardwick JM. 1997. Virus-induced apoptosis. Adv Pharmacol 41:295-336.
    • (1997) Adv Pharmacol , vol.41 , pp. 295-336
    • Hardwick, J.M.1
  • 14
    • 2942618534 scopus 로고    scopus 로고
    • Insights into adenoviral vector production kinetics in acoustic filter-based perfusion cultures
    • DOI 10.1002/bit.20074
    • Henry O, Dormond E, Perrier M, Kamen A. 2004. Insights into adenoviral vector production kinetics in acoustic filter-based perfusion cultures. Biotechnol Bioeng 86(7):765-774. (Pubitemid 38745694)
    • (2004) Biotechnology and Bioengineering , vol.86 , Issue.7 , pp. 765-774
    • Henry, O.1    Dormond, E.2    Perrier, M.3    Kamen, A.4
  • 15
    • 0028278094 scopus 로고
    • Apoptosis: A mechanism of cell killing by influenza a and B viruses
    • Hinshaw VS, Olsen CW, Dybdhal-Sissoko N, Evans D. 1994. Apoptosis: A mechanism of cell killing by influenza A and B viruses. J Virol 68:3667-3673. (Pubitemid 24177391)
    • (1994) Journal of Virology , vol.68 , Issue.6 , pp. 3667-3673
    • Hinshaw, V.S.1    Olsen, C.W.2    Dybdahl-Sissoko, N.3    Evans, D.4
  • 16
    • 3042704538 scopus 로고    scopus 로고
    • Development and optimization of an adenovirus production process
    • DOI 10.1002/jgm.503
    • Kamen A, Henry O. 2004. Development and optimization of an adenovirus production process. J Gene Med 6:184-192. (Pubitemid 40228027)
    • (2004) Journal of Gene Medicine , vol.6 , Issue.SUPPL. 1
    • Kamen, A.1    Henry, O.2
  • 17
    • 0000800331 scopus 로고    scopus 로고
    • Knipe DM, Howley PM, editors. 4th edition. Philadelphia: Lippencott Williams & Wilkins
    • Knipe DM, Howley PM, editors. 2001. Fields virology. Vol.2. 4th edition. Philadelphia: Lippencott Williams & Wilkins. pp. 2265-2300.
    • (2001) Fields Virology , vol.2 , pp. 2265-2300
  • 18
    • 0036317909 scopus 로고    scopus 로고
    • Industrial processes with animal cells
    • Kretzmer G. 2002. Industrial processes with animal cells. Appl Microbiol Biotechnol 59:135-142.
    • (2002) Appl Microbiol Biotechnol , vol.59 , pp. 135-142
    • Kretzmer, G.1
  • 19
    • 0035313535 scopus 로고    scopus 로고
    • Understanding and modulating apoptosis in industrial cell culture
    • DOI 10.1016/S0958-1669(00)00196-8
    • Laken HA, Leonard MW. 2001. Understanding and modulating apoptosis in industrial cell culture. Curr Opin Biotechnol 12:175-179. (Pubitemid 32247405)
    • (2001) Current Opinion in Biotechnology , vol.12 , Issue.2 , pp. 175-179
    • Laken, H.A.1    Leonard, M.W.2
  • 20
    • 14744304517 scopus 로고
    • A new generation of animal cell expression vectors based on the Semliki Forest virus replicon
    • Liljeström P, Garoff H. 1991. A new generation of animal cell expression vectors based on the Semliki Forest virus replicon. Biotechnology 9:1356-1361.
    • (1991) Biotechnology , vol.9 , pp. 1356-1361
    • Liljeström, P.1    Garoff, H.2
  • 21
    • 0035163836 scopus 로고    scopus 로고
    • Caspase activation by adenovirus E4orf4 protein is cell line specific and is mediated by the death receptor pathway
    • DOI 10.1128/JVI.75.2.789-798.2001
    • Livne A, Shtrichman R, Kleinberger T. 2001. Caspase activation by adenovirus E4orf4 protein is cell line specific and is mediated by the death receptor pathway. J Virol 75(2):789-798. (Pubitemid 32037282)
    • (2001) Journal of Virology , vol.75 , Issue.2 , pp. 789-798
    • Livne, A.1    Shtrichman, R.2    Kleinberger, T.3
  • 22
    • 0024242299 scopus 로고    scopus 로고
    • Large-scale insect cell-culture for recombinant protein production
    • Maiorella B, Inlow D, Shauger A, Harano D. 1998. Large-scale insect cell-culture for recombinant protein production. Biotechnology 6:1406-1410.
    • (1998) Biotechnology , vol.6 , pp. 1406-1410
    • Maiorella, B.1    Inlow, D.2    Shauger, A.3    Harano, D.4
  • 23
    • 0033616524 scopus 로고    scopus 로고
    • U937 cells overexpressing bcl-xl are resistant to human immunodeficiency virus-1-induced apoptosis and human immunodeficiency virus-1 replication
    • DOI 10.1006/viro.1999.9599
    • Marshall WL, Datta R, Hanify K, Teng E, Finberg RW. 1999. U937 Cells overexpressing bcl-xl are resistant to human immunodeficiency virus-1-induced apoptosis and human immunodeficiency virus-1 replication. Virology 256:1-7. (Pubitemid 29391820)
    • (1999) Virology , vol.256 , Issue.1 , pp. 1-7
    • Marshall, W.L.1    Datta, R.2    Hanify, K.3    Teng, E.4    Finberg, R.W.5
  • 24
    • 0030440856 scopus 로고    scopus 로고
    • Bcl-2 inhibits apoptosis and extends recombinant protein production in cells infected with sindbis viral vectors
    • Mastrangelo AJ, Hardwick JM, Betenbaugh MJ. 1996. Bcl-2 inhibits apoptosis and extends recombinant protein production in cells infected with sindbis viral vectors. Cytotechnology 22:169-178.
    • (1996) Cytotechnology , vol.22 , pp. 169-178
    • Mastrangelo, A.J.1    Hardwick, J.M.2    Betenbaugh, M.J.3
  • 25
    • 0034607156 scopus 로고    scopus 로고
    • Part 1. Bcl-2 and Bcl-xL limit apoptosis upon infection with alphavirus vectors
    • Mastrangelo AJ, Hardwick JM, Bex F, Betenbaugh MJ. 2000. Part 1. Bcl-2 and Bcl-xL limit apoptosis upon infection with alphavirus vectors. Biotechnol Bioeng 67:544-554.
    • (2000) Biotechnol Bioeng , vol.67 , pp. 544-554
    • Mastrangelo, A.J.1    Hardwick, J.M.2    Bex, F.3    Betenbaugh, M.J.4
  • 26
    • 0028765762 scopus 로고
    • Induction of apoptosis in nutrient-deprived cultures of hybridoma and myeloma cells
    • DOI 10.1002/bit.260440916
    • Mercille S, Massie B. 1994a. Induction of apoptosis in nutrient-deprived cultures of hybridoma and myeloma cells. Biotechnol Bioeng 44:1140-1154. (Pubitemid 24331665)
    • (1994) Biotechnology and Bioengineering , vol.44 , Issue.9 , pp. 1140-1154
    • Mercille, S.1    Massie, B.2
  • 27
    • 0028718665 scopus 로고
    • Induction of apoptosis in oxygen-deprived cultures of hybidoma cells
    • Mercille S, Massie B. 1994b. Induction of apoptosis in oxygen-deprived cultures of hybidoma cells. Cytotechnology 15:117-128.
    • (1994) Cytotechnology , vol.15 , pp. 117-128
    • Mercille, S.1    Massie, B.2
  • 29
    • 0029656251 scopus 로고    scopus 로고
    • Bcl-2 alters influenza virus yield, spread, and hemagglutinin glycosylation
    • Olsen CW, Kehren JC, Dybdhal-Sissoko NR, Hinshaw VS. 1996. bcl-2 alters influenza virus yield, spread, and hemagglutinin glycosylation. J Virol 70(1):663-666. (Pubitemid 3010988)
    • (1996) Journal of Virology , vol.70 , Issue.1 , pp. 663-666
    • Olsen, C.W.1    Kehren, J.C.2    Dybdahl-Sissoko, N.R.3    Hinshaw, V.S.4
  • 30
    • 0035812878 scopus 로고    scopus 로고
    • The response to GS-NS0 myeloma cells to pH shifts and pH perturbations
    • Osman JJ, Birch J, Varley J. 2001. The response to GS-NS0 myeloma cells to pH shifts and pH perturbations. Biotechnol Bioeng 75:63-73.
    • (2001) Biotechnol Bioeng , vol.75 , pp. 63-73
    • Osman, J.J.1    Birch, J.2    Varley, J.3
  • 31
    • 0032442810 scopus 로고    scopus 로고
    • Variable functions of bcl-2 in mediating bioreactor stress-induced apoptosis in hybridoma cells
    • Perani A, Singh RP, Chauhan R, Al-Rubeai M. 1998. Variable functions of bcl-2 in mediating bioreactor stress-induced apoptosis in hybridoma cells. Cytotechnology 28:177-188. (Pubitemid 29188282)
    • (1998) Cytotechnology , vol.28 , Issue.1-3 , pp. 177-188
    • Perani, A.1    Singh, R.P.2    Chauhan, R.3    Al-Rubeai, M.4
  • 32
    • 38949117283 scopus 로고    scopus 로고
    • Monitoring of the adenovirus production process by flow cytometry
    • DOI 10.1021/bp070198s
    • Sandhu KS, Al-Rubeai M. 2008. Monitoring of the adenovirus production process by flow cytometry. Biotechnol Prog 24(1):250-261. (Pubitemid 351231274)
    • (2008) Biotechnology Progress , vol.24 , Issue.1 , pp. 250-261
    • Sandhu, K.S.1    Al-Rubeai, M.2
  • 33
    • 0029665761 scopus 로고    scopus 로고
    • Bcl-2 expression facilitates human immunodeficiency virus type 1-mediated cytopathic effects during acute spreading infections
    • Sandstrom P, Pardi D, Goldsmith C, Chengying D, Diamond AM, Folks TM. 1996. bcl-2 expression facilitates human immunodeficiency virus type-1 mediated cytopathic effects during acute spreading infections. J Virol 70:4617-4622. (Pubitemid 26187457)
    • (1996) Journal of Virology , vol.70 , Issue.7 , pp. 4617-4622
    • Sandstrom, P.A.1    Pardi, D.2    Goldsmith, C.S.3    Chengying, D.4    Diamond, A.M.5    Folks, T.M.6
  • 34
    • 0037139754 scopus 로고    scopus 로고
    • Inhibiting apoptosis in mammalian cell culture using the caspase inhibitor XIAP and deletion mutants
    • Sauerwald TM, Betenbaugh MJ, Oyler GA. 2002. Inhibiting apoptosis in mammalian cell culture using the caspase inhibitor XIAP and deletion mutants. Biotechnol Bioeng 77(6):704-716.
    • (2002) Biotechnol Bioeng , vol.77 , Issue.6 , pp. 704-716
    • Sauerwald, T.M.1    Betenbaugh, M.J.2    Oyler, G.A.3
  • 35
    • 0037419710 scopus 로고    scopus 로고
    • Study of caspase inhibitors for limiting death in mammalian cell cultures
    • Sauerwald TM, Oyler GA, Betenbaugh MJ. 2003. Study of caspase inhibitors for limiting death in mammalian cell cultures. Biotechnol Bioeng 81:329-340.
    • (2003) Biotechnol Bioeng , vol.81 , pp. 329-340
    • Sauerwald, T.M.1    Oyler, G.A.2    Betenbaugh, M.J.3
  • 36
    • 0031034802 scopus 로고    scopus 로고
    • Bcl-2 acts early to restrict semliki forest virus replication and delays virus-induced programmed cell death
    • Scallan MF, Allsopp TE, Fazakerley JK. 1997. bcl-2 acts early to restrict semliki forest virus replication and delays virus-induced programmed cell death. J Virol 71(2):1583-1590.
    • (1997) J Virol , vol.71 , Issue.2 , pp. 1583-1590
    • Scallan, M.F.1    Allsopp, T.E.2    Fazakerley, J.K.3
  • 38
    • 0031554004 scopus 로고    scopus 로고
    • Prevention of hybridoma cell death by bcl-2 during suboptimal culture conditions
    • DOI 10.1002/(SICI)1097-0290(19970405)54:1<1::AID-BIT1>3.0.CO;2-K
    • Simpson NH, Milner AE, Al-Rubeai M. 1997. Prevention of hybridoma cell death by bcl-2 during suboptimal conditions. Biotechnol Bioeng 54:1-116. (Pubitemid 27142527)
    • (1997) Biotechnology and Bioengineering , vol.54 , Issue.1 , pp. 1-16
    • Simpson, N.H.1    Milner, A.E.2    Al-Rubeai, M.3
  • 40
    • 0030571210 scopus 로고    scopus 로고
    • Enhancement of survivability of mammalian cells by overexpression of the apoptosis-suppressor gene bcl-2
    • DOI 10.1002/(SICI)1097-0290(19961005)52:1<166::AID-BIT17>3.3.CO;2-5
    • Singh RP, Emery AN, Al-Rubeai M. 1996. Enhancement of survivability of mammalian cells by overexpression of the apoptosis-suppressor gene bcl-2. Biotechnol Bioeng 52:166-175. (Pubitemid 26317951)
    • (1996) Biotechnology and Bioengineering , vol.52 , Issue.1 , pp. 166-175
    • Singh, R.P.1    Emery, A.N.2    Al-Rubeai, M.3
  • 41
    • 0035868714 scopus 로고    scopus 로고
    • Adenovirus-activated PKA and p38/MAPK pathways boost microtubule-mediated nuclear targeting of virus
    • DOI 10.1093/emboj/20.6.1310
    • Suomalainen M, Nakano MY, Boucke K, Keller S, Greber UF. 2001. adenovirus-activated PKA and p38/MAPK pathways boost microtubule mediated nuclear targeting of virus. EMBO J 20(6):1310-1319. (Pubitemid 32233971)
    • (2001) EMBO Journal , vol.20 , Issue.6 , pp. 1310-1319
    • Suomalainen, M.1    Nakano, M.Y.2    Boucke, K.3    Keller, S.4    Greber, U.F.5
  • 42
    • 21644458683 scopus 로고    scopus 로고
    • Suppression of apoptosis in perfusion culture of Myeloma NS0 cells enhances cell growth but reduces antibody productivity
    • DOI 10.1023/B:APPT.0000045792.63249.5a
    • Tey BT, Al-Rubeai M. 2004. Suppression of apoptosis in perfusion culture of myeloma NS0 cells enhances cell growth but reduces antibody productivity. Apoptosis 9:843-852. (Pubitemid 40941212)
    • (2004) Apoptosis , vol.9 , Issue.6 , pp. 843-852
    • Tey, B.T.1    Al-Rubeai, M.2
  • 43
    • 0034724930 scopus 로고    scopus 로고
    • Bcl-2 mediated suppression of apoptosis in myeloma NS0 cultures
    • DOI 10.1016/S0168-1656(00)00223-6, PII S0168165600002236
    • Tey BT, Singh RP, Piredda L, Piacentini M, Al-Rubeai M. 2000. Bcl-2 mediated suppression of apoptosis in myeloma NS0 cultures. J Biotechnol 79:147-159. (Pubitemid 30254206)
    • (2000) Journal of Biotechnology , vol.79 , Issue.2 , pp. 147-159
    • Tey, B.T.1    Singh, R.P.2    Piredda, L.3    Piacentini, M.4    Al-Rubeai, M.5
  • 44
    • 33747354676 scopus 로고    scopus 로고
    • Cell culture processes for the production of viral vectors for gene therapy purposes
    • Warnock JN, Merten OW, Al-RubeaiM. 2006. Cell culture processes for the production of viral vectors for gene therapy purposes. Cytotechnology 50:141-162.
    • (2006) Cytotechnology , vol.50 , pp. 141-162
    • Warnock, J.N.1    Merten, O.W.2    Al-Rubeai, M.3
  • 45
    • 0023783863 scopus 로고
    • Role of the adenovirus E1B 19,000-dalton tumor antigen in regulating early gene expression
    • White E, Denton A, Stillman B. 1988. Role of the adenovirus E1B 19,000-dalton tumor antigen in regulating early gene expression. J Virol 62:3445-3454. (Pubitemid 18205196)
    • (1988) Journal of Virology , vol.62 , Issue.9 , pp. 3445-3454
    • White, E.1    Denton, A.2    Stillman, B.3
  • 46
    • 0038521274 scopus 로고    scopus 로고
    • Caspase 3 activation is essential for efficient influenza virus propagation
    • DOI 10.1093/emboj/cdg279
    • Wurzer WJ, Planz O, Ehrhardt C, Giner M, Silberzhan T, Pleschka S, Ludwig S. 2003. Caspase 3 activation is essential for efficient influenza virus propagation. EMBO J 22(11):2717-2728. (Pubitemid 36712368)
    • (2003) EMBO Journal , vol.22 , Issue.11 , pp. 2717-2728
    • Wurzer, W.J.1    Planz, O.2    Ehrhardt, C.3    Giner, M.4    Silberzahn, T.5    Pleschka, S.6    Ludwig, S.7
  • 47
    • 2542447236 scopus 로고    scopus 로고
    • Perfusion cultures of human tumor cells: A scalable production platform for oncolytic adenoviral vectors
    • DOI 10.1002/bit.20158
    • Yuk INY, Olsen MM, Geyer S, Forestell SP. 2004. Perfusion culture of human tumor cells: A scalable production platform for oncolytic adenoviral vectors. Biotechnol Bioeng 86(6):637-642. (Pubitemid 38685203)
    • (2004) Biotechnology and Bioengineering , vol.86 , Issue.6 , pp. 637-642
    • Yuk, I.H.Y.1    Olsen, M.M.2    Geyer, S.3    Forestell, S.P.4
  • 48
    • 0033526899 scopus 로고    scopus 로고
    • Serum protects protein-free competent chinese hamster ovary cells against apoptosis induced by nutrient deprivation in batch culture
    • DOI 10.1002/(SICI)1097-0290(19990705)64:1<108::AID-BIT12>3.0.CO;2-B
    • Zanghi JA, Fussenegger M, Bailey JE. 1999. Serum protects protein-free competent Chinese hamster ovary cells against apoptosis induced by nutrient deprivation in batch culture. Biotechnol Bioeng 64:108-119. (Pubitemid 29252318)
    • (1999) Biotechnology and Bioengineering , vol.64 , Issue.1 , pp. 108-119
    • Zanghi, J.A.1    Fussenegger, M.2    Bailey, J.E.3


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