Can we change brain functioning with cognition-focused interventions in Alzheimer's disease? the role of functional neuroimaging

Restorative Neurology and Neuroscience

Volumn 27, Issue 5, 2009, Pages 473-491

  Van Paasschen, Jorien ^a   Clare, Linda ^a   Woods, Robert T ^a   Linden, David E J ^a  

^a BANGOR UNIVERSITY   (United Kingdom)

Author keywords

Associative memory; Dementia; FMRI; Mild cognitive impairment; Neural plasticity; Treatment outcome

Indexed keywords

AGING; ALZHEIMER DISEASE; ASSOCIATIVE MEMORY; BRAIN DEPTH STIMULATION; BRAIN FUNCTION; COGNITION; EDUCATIONAL STATUS; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HIPPOCAMPUS; HUMAN; MEMORY; MILD COGNITIVE IMPAIRMENT; NERVE CELL PLASTICITY; NEUROIMAGING; PRIORITY JOURNAL; REVIEW; TASK PERFORMANCE;

AGING; ALZHEIMER DISEASE; BRAIN; COGNITION; EXECUTIVE FUNCTION; HUMANS; MAGNETIC RESONANCE IMAGING; MEMORY;

EID: 70350491046     PISSN: 09226028     EISSN: None     Source Type: Journal    
DOI: 10.3233/RNN-2009-0494     Document Type: Review

References (63)

1. Achim, A. M., & Lepage, M. (2005). Neural correlates of memory for items and for associations: an event-related functional magnetic resonance imaging study. Journal of Cognitive Neuroscience, 17, 652-667. (Pubitemid 40478287)
2. Aylward, E. H., Richards, T. L., Berninger, V.W., Nagy,W. E., Field, K. M., Grimme, A. C., et al. (2003). Instructional treatment associated with changes in brain activation in children with dyslexia. Neurology, 61, 212-219.
3. Baddeley, A. D., Emslie, H., & Nimmo-Smith, I. (1994). Doors and People: A Test of Visual and Verbal Recall and Recognition. Bury St. Edmunds: Thames Valley Test Company.
4. Barrett, A. M., Crucian, G. P., Schwartz, R. L., & Heilman, K. M. (2000). Testing memory for self-generated items in dementia: method makes a difference. Neurology, 54, 1258-1264.
5. Buckner, R. L., Snyder, A. Z., Shannon, B. J., LaRossa, G., Sachs, R., Fotenos, A. F., et al. (2005). Molecular, structural, and functional characterization of Alzheimer's disease: evidence for a relationship between default activity, amyloid, and memory. J Neurosci, 25, 7709-7717.
6. Celone, K. A., Calhoun, V. D., Dickerson, B. C., Atri, A., Chua, E. F., Miller, S. L., et al. (2006). Alterations in memory networks in mild cognitive impairment and Alzheimer's disease: an independent component analysis. J Neurosci, 26, 10222-10231.
7. Chalfonte, B. L., & Johnson, M. K. (1996). Feature memory and binding in young and older adults. Mem Cognit, 24, 403-416.
8. Clare, L. (2007). Neuropsychological rehabilitation and people with dementia. Hove: Psychology Press.
9. Clare, L.,Van Paasschen, J., Evans, S., Parkinson, C.,Woods, R.T.,& Linden, D. E. (in press). Goal-oriented cognitive rehabilitation for an individual with Mild Cognitive Impairment: behavioural and neuroimaging outcomes. Neurcase.
10. Clare, L.,Wilson, B. A., Carter, G., Breen, K., Gosses, A.,&Hodges, J. R. (2000). Intervening with everyday memory problems in dementia of Alzheimer type: an errorless learning approach. J Clin Exp Neuropsychol, 22, 132-146.
11. Clare, L.,Wilson, B. A., Carter, G., Roth, I., & Hodges, J. R. (2002). Relearning face-name associations in early Alzheimer's disease. Neuropsychology, 16, 538-547.
12. Dale, A. M., & Buckner, R. L. (1997). Selective averaging of rapidly presented individual trials using fMRI. Human BrainMapping, 5, 329-340.
13. Daselaar, S. M., Veltman, D. J., Rombouts, S. A., Raaijmakers, J. G., & Jonker, C. (2003). Neuroanatomical correlates of episodic encoding and retrieval in young and elderly subjects. Brain, 126, 43-56.
14. Department for Children, Schools, and Families (2007). Retrieved 15 August, 2008, from http://www.dcsf.gov.uk/rsgateway/DB/ SFR/s000777/sfrdius01- 2008.pdf.
15. Dickerson, B. C., Salat, D. H., Greve, D. N., Chua, E. F., Rand- Giovannetti, E., Rentz, D. M., et al. (2005). Increased hippocampal activation in mild cognitive impairment compared to normal aging and AD. Neurology, 65, 404-411.
16. Donders, F. C. (1969). On the speed of mental processes. Acta Psychol (Amst), 30, 412-431.
17. Folstein, M. F., Folstein, S. E.,&McHugh, P. R. (1975). Mini-mental state. A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res, 12, 189-198.
18. Fowler, K. S., Saling, M. M., Conway, E. L., Semple, J. M., & Louis, W. J. (2002). Paired associate performance in the early detection of DAT. J Int Neuropsychol Soc, 8, 58-71.
19. Friston, K. J., Price, C. J., Fletcher, P., Moore, C., Frackowiak, R. S., & Dolan, R. J. (1996). The trouble with cognitive subtraction. Neuroimage, 4, 97-104.
20. Goekoop, R., Scheltens, P., Barkhof, F., & Rombouts, S. A. (2006). Cholinergic challenge in Alzheimer patients and mild cognitive impairment differentially affects hippocampal activation-a pharmacological fMRI study. Brain, 129, 141-157.
21. Gould, R. L., Brown, R. G., Owen, A. M., Bullmore, E. T.,Williams, S. C., & Howard, R. J. (2005). Functional neuroanatomy of successful paired associate learning in Alzheimer's disease. Am J Psychiatry, 162, 2049-2060.
22. Grady, C. L. (2008). Cognitive neuroscience of aging. Ann N Y Acad Sci, 1124, 127-144.
23. Grady, C. L., & Craik, F. I. (2000). Changes in memory processing with age. Curr Opin Neurobiol, 10, 224-231.
24. Grady, C. L., McIntosh, A. R., Beig, S., Keightley, M. L., Burian, H., &Black, S. E. (2003). Evidence from functional neuroimaging of a compensatory prefrontal network in Alzheimer's disease. J Neurosci, 23, 986-993.
25. Greene, J. D., Baddeley, A. D., & Hodges, J. R. (1996). Analysis of the episodic memory deficit in early Alzheimer's disease: evidence from the doors and people test. Neuropsychologia, 34, 537-551.
26. Herholz, K., Ehlen, P., Kessler, J., Strotmann, T., Kalbe, E., & Markowitsch, H. J. (2001). Learning face-name associations and the effect of age and performance: a PET activation study. Neuropsychologia, 39, 643-650.
27. Huettel, S. A., Song, A. W., & McCarthy, G. (2004). Functional Magnetic Resonance Imaging. Sunderland, MA: Sinauer Associates.
28. Kircher, T. T., Erb, M., Grodd, W., & Leube, D. T. (2005). Cortical activation during cholinesterase-inhibitor treatment in Alzheimer disease: preliminary findings from a pharmacofMRI study. Am J Geriatr Psychiatry, 13, 1006-1013.
29. Laatsch, L.,&Krisky, C. (2006). Changes in fMRI activation following rehabilitation of reading and visual processing deficits in subjects with traumatic brain injury. Brain Inj, 20, 1367-1375.
30. Laatsch, L. K., Thulborn, K. R., Krisky, C. M., Shobat, D. M., & Sweeney, J. A. (2004). Investigating the neurobiological basis of cognitive rehabilitation therapy with fMRI. Brain Inj, 18, 957-974.
31. Lindeboom, J., Schmand, B., Tulner, L., Walstra, G., & Jonker, C. (2002). Visual association test to detect early dementia of the Alzheimer type. J Neurol Neurosurg Psychiatry, 73, 126-133.
32. Linden, D. E. (2006). How psychotherapy changes the brain-the contribution of functional neuroimaging. Mol Psychiatry, 11, 528-538.
33. Linden, D. E. (2007). The working memory networks of the human brain. Neuroscientist, 13, 257-267.
34. Logan, J. M., Sanders, A. L., Snyder, A. Z., Morris, J. C., & Buckner, R. L. (2002). Under-recruitment and nonselective recruitment: dissociable neural mechanisms associated with aging. Neuron, 33, 827-840.
35. Lustig, C., Snyder, A. Z., Bhakta, M., O'Brien, K. C., McAvoy, M., Raichle, M. E., et al. (2003). Functional deactivations: change with age and dementia of the Alzheimer type. Proc Natl Acad Sci USA, 100, 14504-14509.
36. Martinez, A. M., & Benavente, R. (1998). The AR Face database. CVC technical report # 24, June.
37. Naveh-Benjamin, M. (2000). Adult age differences in memory performance: tests of an associative deficit hypothesis. J Exp Psychol Learn Mem Cogn, 26, 1170-1187.
38. Naveh-Benjamin, M., Guez, J., Kilb, A., & Reedy, S. (2004). The associative memory deficit of older adults: further support using face-name associations. Psychol Aging, 19, 541-546.
39. Olesen, P. J.,Westerberg, H., & Klingberg, T. (2004). Increased prefrontal and parietal activity after training of working memory. Nat Neurosci, 7, 75-79.
40. Pariente, J., Cole, S., Henson, R., Clare, L., Kennedy, A., Rossor, M., et al. (2005). Alzheimer's patients engage an alternative network during a memory task. Ann Neurol, 58, 870-879.
41. Petersen, R. C. (2004). Mild cognitive impairment as a diagnostic entity. Journal of Internal Medicine, 256, 183-194.
42. Petersen, S. E., Fox, P. T., Posner,M. I., Mintun, M. A.,&Raichle, M. E. (1989). Positron emission tomography of the processing of single words. Journal of Cognitive Neuroscience, 1, 153-170.
43. Petrella, J. R., Krishnan, S., Slavin, M. J., Tran, T. T., Murty, L., & Doraiswamy, P. M. (2006). Mild cognitive impairment: evaluation with 4-T functional MR imaging. Radiology, 240, 177-186.
44. Petrella, J. R., Wang, L., Krishnan, S., Slavin, M. J., Prince, S. E., Tran, T. T., et al. (2007). Cortical deactivation in mild cognitive impairment: high-field-strength functional MR imaging. Radiology, 245, 224-235. (Pubitemid 47417806)
45. Prvulovic, D., Van de Ven, V., Sack, A. T., Maurer, K., & Linden, D. E. (2005). Functional activation imaging in aging and dementia. Psychiatry Research, 140, 97-113.
46. Raichle, M. E., MacLeod, A. M., Snyder, A. Z., Powers, W. J., Gusnard, D. A., & Shulman, G. L. (2001). A default mode of brain function. Proc Natl Acad Sci USA, 98, 676-682.
47. Rand-Giovannetti, E., Chua, E. F., Driscoll, A. E., Schacter, D. L., Albert, M. S., & Sperling, R. A. (2006). Hippocampal and neocortical activation during repetitive encoding in older persons. Neurobiol Aging, 27, 173-182.
48. Rombouts, S. A., Barkhof, F.,Van Meel, C. S.,&Scheltens, P. (2002). Alterations in brain activation during cholinergic enhancement with rivastigmine in Alzheimer's disease. J Neurol Neurosurg Psychiatry, 73, 665-671.
49. Sandstrom, C. K., Krishnan, S., Slavin, M. J., Tran, T. T., Doraiswamy, P. M., & Petrella, J. R. (2006). Hippocampal atrophy confounds template-based functional MR imaging measures of hippocampal activation in patients with mild cognitive impairment. AJNR Am J Neuroradiol, 27, 1622-1627.
50. Saykin, A. J.,Wishart, H. A., Rabin, L. A., Flashman, L. A., McHugh, T. L., Mamourian, A. C., et al. (2004). Cholinergic enhancement of frontal lobe activity in mild cognitive impairment. Brain, 127, 1574-1583.
51. Sperling, R. A., Bates, J. F., Chua, E. F., Cocchiarella, A. J., Rentz, D. M., Rosen, B. R., et al. (2003a). fMRI studies of associative encoding in young and elderly controls and mild Alzheimer's disease. J Neurol Neurosurg Psychiatry, 74, 44-50.
52. Sperling, R. A., Chua, E., Cocchiarella, A., Rand-Giovannetti, E., Poldrack, R., Schacter, D. L., et al. (2003b). Putting names to faces: successful encoding of associative memories activates the anterior hippocampal formation. Neuroimage, 20, 1400-1410.
53. Talairach, J., & Tournoux, P. (1988). Co-Planar Stereotaxic Atlas of the Human Brain: 3-Dimensional Proportional System: An Approach to Cerebral Imaging. Stuttgart: Thieme Medical Publishers.
54. Temple, E., Deutsch, G. K., Poldrack, R. A., Miller, S. L., Tallal, P., Merzenich, M. M., et al. (2003). Neural deficits in children with dyslexia ameliorated by behavioral remediation: evidence from functional MRI. Proc Natl Acad Sci USA, 100, 2860-2865.
55. Troyer, A. K., Häfliger, A., Cadieux, M. J., & Craik, F. I. (2006). Name and face learning in older adults: effects of level of processing, self-generation, and intention to learn. J Gerontol B Psychol Sci Soc Sci, 61, P67-74.
56. US Census Bureau (2006). Retrieved 15 August, 2008, from http:// factfinder.census.gov/servlet/STTable? bm=y&-geo id= 01000US&-qr name=ACS 2006 EST G00 S1501&-ds name =ACS 2006 EST G00 .
57. Warrington, E. K. (1984). Recognition Memory Test manual. Windsor, UK: Nfer-Nelson.
58. Wechsler, D. (1997). Wechsler Memory Scale - Third edition. San Antonio, TX: Psychological Corporation.
59. Westerberg, H., & Klingberg, T. (2007). Changes in cortical activity after training of working memory-a single-subject analysis. Physiol Behav, 92, 186-192.
60. Wexler, B. E., Anderson, M., Fulbright, R. K., & Gore, J. C. (2000). Preliminary evidence of improved verbal working memory performance and normalization of task-related frontal lobe activation in schizophrenia following cognitive exercises. Am J Psychiatry, 157, 1694-1697.
61. Wilkinson, D., & Halligan, P. (2004). The relevance of behavioural measures for functional-imaging studies of cognition. Nat Rev Neurosci, 5, 67-73.
62. Wilson, B., Cockburn, J., & Baddeley, A. D. (1985). The Rivermead Behavioural Memory Test. Titchfield: Thames Valley Test Company.
63. Wykes, T., Brammer, M., Mellers, J., Bray, P., Reeder, C., Williams, C., et al. (2002). Effects on the brain of a psychological treatment: cognitive remediation therapy: functional magnetic resonance imaging in schizophrenia. Br J Psychiatry, 181, 144-152.