The linker region in receptor guanylyl cyclases is a key regulatory module. Mutational analysis of guanylyl cyclase C

Journal of Biological Chemistry

Volumn 284, Issue 40, 2009, Pages 27135-27145

  Saha, Sayanti ^a   Biswas, Kabir Hassan ^a   Kondapalli, Chandana ^a   Isloor, Nishitha ^a   Visweswariah, Sandhya S ^a  

^a INDIAN INSTITUTE OF SCIENCE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ATP BINDING; BASAL ACTIVITIES; CATALYTIC DOMAINS; COILED COIL PEPTIDE; COILED-COIL STRUCTURE; CYCLASES; EXTRACELLULAR DOMAINS; GUANYLYL CYCLASE; HOMOLOGY DOMAIN; HYDROPHOBIC INTERACTIONS; INTRACELLULAR DOMAIN; LIGAND BINDING; LINKER REGION; MULTIDOMAIN PROTEINS; MUTATIONAL ANALYSIS; NONIONIC DETERGENTS; POINT MUTATIONS;

AMINES; AMINO ACIDS; BIOCHEMISTRY; DIMERIZATION; ENZYME ACTIVITY; HYDROPHOBICITY; LIGANDS; ORGANIC ACIDS; SOAPS (DETERGENTS);

BIOACTIVITY;

ADENOSINE TRIPHOSPHATE; ATRIAL NATRIURETIC FACTOR RECEPTOR; GUANYLATE CYCLASE; ISOLEUCINE; LEUCINE; VALINE; DETERGENT; ENTEROTOXIN RECEPTOR; LIGAND; RECEPTOR;

ALPHA HELIX; ARTICLE; CARBOXY TERMINAL SEQUENCE; COILED BODY; CONTROLLED STUDY; DIMERIZATION; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME REGULATION; HUMAN; HUMAN CELL; HYDROPHOBICITY; LIGAND BINDING; MUTATIONAL ANALYSIS; OLIGOMERIZATION; POINT MUTATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN SECONDARY STRUCTURE; PROTEIN STRUCTURE; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; AMINO ACID SEQUENCE; ANIMAL; CELL LINE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECT; ENZYME ACTIVATION; GENETICS; METABOLISM; MOLECULAR GENETICS; MOUSE; MUTAGENESIS; PROTEIN TERTIARY STRUCTURE; RAT;

AMINO ACID SEQUENCE; ANIMALS; CELL LINE; DETERGENTS; ENZYME ACTIVATION; GUANYLATE CYCLASE; HUMANS; HYDROPHOBICITY; LIGANDS; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS; POINT MUTATION; PROTEIN STRUCTURE, TERTIARY; RATS; RECEPTORS, PEPTIDE;

EID: 70350482887     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.020032     Document Type: Article

References (52)

1. Padayatti, P. S., Pattanaik, P., Ma, X., and van den Akker, F. (2004) Pharmacol. Ther. 104, 83-99
2. Jaleel, M., Saha, S., Shenoy, A. R., and Visweswariah, S. S. (2006) Biochemistry 45, 1888-1898
3. Bhandari, R., Srinivasan, N., Mahaboobi, M., Ghanekar, Y., Suguna, K., and Visweswariah, S. S. (2001) Biochemistry 40, 9196-9206
4. Linder, J. U., and Schultz, J. E. (2003) Cell. Signal. 15, 1081-1089
5. Rauch, A., Leipelt, M., Russwurm, M., and Steegborn, C. (2008) Proc. Natl. Acad. Sci. U.S.A. 105, 15720-15725
6. Winger, J. A., Derbyshire, E. R., Lamers, M. H., Marletta, M. A., and Kuriyan, J. (2008) BMC Struct. Biol. 8, 42
7. Forte, L. R. (1999) Regul. Pept. 81, 25-39
8. Vaandrager, A. B. (2002) Mol. Cell. Biochem. 230, 73-83
9. Forte, L. R., Krause, W. J., and Freeman, R. H. (1989) Am. J. Physiol. 257, F874-F881
10. Jaleel, M., London, R. M., Eber, S. L., Forte, L. R., and Visweswariah, S. S. (2002) Biol. Reprod. 67, 1975-1980
11. Nandi, A., Bhandari, R., and Visweswariah, S. S. (1997) J. Cell. Biochem. 66, 500-511
12. Qian, X., Prabhakar, S., Nandi, A., Visweswariah, S. S., and Goy, M. F. (2000) Endocrinology 141, 3210-3224
13. Biswas, K. H., Shenoy, A. R., Dutta, A., and Visweswariah, S. S. (2009) J. Mol. Evol. 68, 587-602
14. Hirayama, T., Wada, A., Hidaka, Y., Fujisawa, J., Takeda, Y., and Shimonishi, Y. (1993) Microb. Pathog. 15, 283-291
15. van den Akker, F., Zhang, X., Miyagi, M., Huo, X., Misono, K. S., and Yee, V. C. (2000) Nature 406, 101-104
16. Ramamurthy, V., Tucker, C., Wilkie, S. E., Daggett, V., Hunt, D. M., and Hurley, J. B. (2001) J. Biol. Chem. 276, 26218-26229
17. Vijayachandra, K., Guruprasad, M., Bhandari, R., Manjunath, U. H., Somesh, B. P., Srinivasan, N., Suguna, K., and Visweswariah, S. S. (2000) Biochemistry 39, 16075-16083
18. Wilson, E. M., and Chinkers, M. (1995) Biochemistry 34, 4696-4701
19. Shiga, T., and Suzuki, N. (2005) Zool. Sci. 22, 735-742
20. Zhou, Z., Gross, S., Roussos, C., Meurer, S., Müller-Esterl, W., and Papa-petropoulos, A. (2004) J. Biol. Chem. 279, 24935-24943
21. Smith, M., Whittock, N., Searle, A., Croft, M., Brewer, C., and Cole, M. (2007) Eye 21, 1220-1225
22. Singh, S., Singh, G., Heim, J. M., and Gerzer, R. (1991) Biochem. Biophys. Res. Commun. 179, 1455-1463
23. Shenoy, A. R., and Visweswariah, S. S. (2003) Anal. Biochem. 319, 335-336
24. Chinkers, M., Garbers, D. L., Chang, M. S., Lowe, D. G., Chin, H. M., Goeddel, D. V., and Schulz, S. (1989) Nature 338, 78-83
25. Visweswariah, S. S., Ramachandran, V., Ramamohan, S., Das, G., and Ramachandran, J. (1994) Eur. J. Biochem. 219, 727-736
26. Zor, T., and Selinger, Z. (1996) Anal. Biochem. 236, 302-308
27. Do, C. B., Mahabhashyam, M. S., Brudno, M., and Batzoglou, S. (2005) Genome Res. 15, 330-340
28. Eswar, N., Eramian, D., Webb, B., Shen, M. Y., and Sali, A. (2008) Methods Mol. Biol. 426, 145-159
29. Laskowski, R. A., M. M. W., Moss, D. S., and Thornton, J. M. (1993) J. Appl. Crystallogr. 26, 283-291
30. Cuff, J. A., Clamp, M. E., Siddiqui, A. S., Finlay, M., and Barton, G. J. (1998) Bioinformatics 14, 892-893
31. McGuffin, L. J., Bryson, K., and Jones, D. T. (2000) Bioinformatics 16, 404-405
32. Lupas, A., Van Dyke, M., and Stock, J. (1991) Science 252, 1162-1164
33. Yu, Y. B. (2002) Adv. Drug Deliv. Rev. 54, 1113-1129
34. Ghanekar, Y., Chandrashaker, A., Tatu, U., and Visweswariah, S. S. (2004) Biochem. J. 379, 653-663
35. Liu, Y., Ruoho, A. E., Rao, V. D., and Hurley, J. H. (1997) Proc. Natl. Acad. Sci. U.S.A. 94, 13414-13419
36. Tesmer, J. J., Sunahara, R. K., Gilman, A. G., and Sprang, S. R. (1997) Science 278, 1907-1916
37. Campanella, J. J., Bitincka, L., and Smalley, J. (2003) BMC Bioinformatics 4, 29
38. Abbey, S. E., and Potter, L. R. (2002) J. Biol. Chem. 277, 42423-42430
39. Bryan, P. M., Smirnov, D., Smolenski, A., Feil, S., Feil, R., Hofmann, F., Lohmann, S., and Potter, L. R. (2006) Biochemistry 45, 1295-1303
40. Antos, L. K., Abbey-Hosch, S. E., Flora, D. R., and Potter, L. R. (2005) J. Biol. Chem. 280, 26928-26932
41. Finney, L. A., and O'Halloran, T. V. (2003) Science 300, 931-936
42. Seebeck, B., Reulecke, I., Kämper, A., and Rarey, M. (2008) Proteins 71, 1237-1254
43. Kitiratschky, V. B., Wilke, R., Renner, A. B., Kellner, U., Vadalà, M., Birch, D. G., Wissinger, B., Zrenner, E., and Kohl, S. (2008) Invest. Ophthalmol. Vis. Sci. 49, 5015-5023
44. Koch, K. W., Duda, T., and Sharma, R. K. (2002) Mol. Cell. Biochem. 230, 97-106
45. Duda, T., Krishnan, A., Venkataraman, V., Lange, C., Koch, K. W., and Sharma, R. K. (1999) Biochemistry 38, 13912-13919
46. Tucker, C. L., Woodcock, S. C., Kelsell, R. E., Ramamurthy, V., Hunt, D. M., and Hurley, J. B. (1999) Proc. Natl. Acad. Sci. U.S.A. 96, 9039-9044
47. Wedel, B. J., Foster, D. C., Miller, D. E., and Garbers, D. L. (1997) Proc. Natl. Acad. Sci. U.S.A. 94, 459-462
48. Tews, I., Findeisen, F., Sinning, I., Schultz, A., Schultz, J. E., and Linder, J. U. (2005) Science 308, 1020-1023
49. Linder, J. U., Schultz, A., and Schultz, J. E. (2002) J. Biol. Chem. 277, 15271-15276
50. Linder, J. U., Hammer, A., and Schultz, J. E. (2004) Eur. J. Biochem. 271, 2446-2451
51. Edgar, R. C. (2004) Nucleic Acids Res. 32, 1792-1797
52. Young, J. M., Waters, H., Dong, C., Fülle, H. J., and Liman, E. R. (2007) PLoS ONE 2, e884