Structural insights into the regulation and the activation mechanism of mammalian guanylyl cyclases

Pharmacology and Therapeutics

Volumn 104, Issue 2, 2004, Pages 83-99

  Padayatti, Pius S ^a   Pattanaik, Priyaranjan ^a   Ma, Xiaolei ^a   Van Den Akker, Focco ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Crystal structure; Guanylyl cyclase receptor; Natriuretic peptide receptor; Signal transduction; Soluble guanylyl cyclase

Indexed keywords

CYCLIC GMP; GLYCERYL TRINITRATE; GUANYLATE CYCLASE; NESIRITIDE;

AMINO TERMINAL SEQUENCE; BINDING AFFINITY; BINDING SITE; BIOAVAILABILITY; BONE GROWTH; CONFORMATION; CONGESTIVE HEART FAILURE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME REGULATION; GLYCOSYLATION; HUMAN; MEMBRANE; NONHUMAN; OLIGOMERIZATION; PHYSIOLOGY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; REVIEW; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; STOICHIOMETRY; VASODILATATION; VISION;

ANIMALS; CYCLIC GMP; GUANYLATE CYCLASE; HUMANS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, ATRIAL NATRIURETIC FACTOR; RECEPTORS, PEPTIDE;

EID: 7044233148     PISSN: 01637258     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2004.08.003     Document Type: Review

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