The application of genomics to emerging zoonotic viral diseases

PLoS Pathogens

Volumn 5, Issue 10, 2009, Pages

  Haagmans, Bart L ^a   Andeweg, Arno C ^a   Osterhaus, Albert D M E ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR ANTAGONIST; CXCR3 RECEPTOR ANTAGONIST; MESSENGER RNA; PEGINTERFERON ALPHA; UNCLASSIFIED DRUG; VIRUS HEMAGGLUTININ;

ANIMAL DISEASE; EVOLUTIONARY ADAPTATION; GENE EXPRESSION PROFILING; GENE SEQUENCE; GENETIC VARIABILITY; GENOME ANALYSIS; GENOMICS; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNE RESPONSE; INFLUENZA; INFLUENZA VIRUS A H1N1; INFLUENZA VIRUS A H5N1; MICROARRAY ANALYSIS; MOLECULAR MECHANICS; NONHUMAN; REVIEW; SARS CORONAVIRUS; SIMIAN IMMUNODEFICIENCY VIRUS; SINGLE NUCLEOTIDE POLYMORPHISM; TREATMENT OUTCOME; VIRUS CELL INTERACTION; VIRUS ENTRY; VIRUS GENOME; VIRUS INFECTION; VIRUS TRANSMISSION; ANIMAL; COMMUNICABLE DISEASE; DISEASE TRANSMISSION; GENETICS; INFLUENZA VIRUS A; ORTHOMYXOVIRUS INFECTION; SEVERE ACUTE RESPIRATORY SYNDROME; VIROLOGY; ZOONOSIS;

ANIMALIA;

ANIMALS; COMMUNICABLE DISEASES, EMERGING; GENOMICS; HUMANS; INFLUENZA A VIRUS; INFLUENZA, HUMAN; ORTHOMYXOVIRIDAE INFECTIONS; SARS VIRUS; SEVERE ACUTE RESPIRATORY SYNDROME; ZOONOSES;

EID: 70350472844     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1000557     Document Type: Review

References (29)

1. Osterhaus A (2001) Catastrophes after crossing species barriers. Philos Trans Soc Lond B Biol Sci 356: 791-793.
2. Kuiken T, Leighton FA, Fouchier RA, LeDuc JW, Peiris JS, et al. (2005) Public health. Pathogen surveillance in animals. Science 309: 1680-1681.
3. Field HE, Mackenzie JS, Daszak P (2007) Henipaviruses: Emerging paramyxoviruses associated with fruit bats. Curr Top Microbiol Immunol 315: 133-159.
4. Rivers TM (1937) Viruses and Koch's postulates. J Bacteriol 33: 1-12.
5. Worobey M, Gemmel M, Teuwen DE, Haselkorn T, Kunstman K, et al. (2008) Direct evidence of extensive diversity of HIV-1 in Kinshasa by 1960. Nature 455: 661-664.
6. Lederer S, Favre D, Walters KA, Proll S, Kanwar B, et al. (2009) Transcriptional profiling in pathogenic and non-pathogenic SIV infections reveals significant distinctions in kinetics and tissue compartmentalization. PLoS Pathog 5: e1000296. doi:10.1371/journal.ppat.1000296.
7. Mandl JN, Barry AP, Vanderford TH, Kozyr N, Chavan R, et al. (2008) Divergent TLR7 and TLR9 signaling and type I interferon production distinguish pathogenic and nonpathogenic AIDS virus infections. Nat Med 14: 1077-1087.
8. Munster VJ, Baas C, Lexmond P, Waldenström J, Wallensten A, et al. (2007) Spatial, temporal, and species variation in prevalence of influenza A viruses in wild migratory birds. PLoS Pathog 3: e61. doi:10.1371/journal.ppat. 0030061.
9. Keawcharoen J, van Riel D, van Amerongen G, Bestebroer T, Beyer WE, et al. (2008) Wild ducks as long-distance vectors of highly pathogenic avian influenza virus (H5N1). Emerg Infect Dis 4: 600-607.
10. Hatta M, Gao P, Halfmann P, Kawaoka Y (2001) Molecular basis for high virulence of Hong Kong H5N1 influenza A viruses. Science 293: 1840-1842.
11. van Riel D, Munster VJ, de Wit E, Rimmelzwaan GF, Fouchier RA, et al. (2006) H5N1 virus attachment to lower respiratory tract. Science 312: 399.
12. Yamada S, Suzuki Y, Suzuki T, Le MQ, Nidom CA, et al. (2006) Haemagglutinin mutations responsible for the binding of H5N1 influenza A viruses to human-type receptors. Nature 444: 378-382.
13. Smith DJ, Lapedes AS, de Jong JC, Bestebroer TM, Rimmelzwaan GF, et al. (2004) Mapping the antigenic and genetic evolution of influenza virus. Science 305: 371-376.
14. Geiss GK, Salvatore M, Tumpey TM, Carter VS, Wang X, et al. (2002) Cellular transcriptional profiling in influenza A virus-infected lung epithelial cells: The role of the nonstructural NS1 protein in the evasion of the host innate defense and its potential contribution to pandemic influenza. Proc Natl Acad Sci U S A 99: 10736-10741.
15. Kobasa D, Jones SM, Shinya K, Kash JC, Copps J, et al. (2007) Aberrant innate immune response in lethal infection of macaques with the 1918 influenza virus. Nature 445: 319-323.
16. Baskin CR, Bielefeldt-Ohmann H, Tumpey TM, Sabourin PJ, Long JP, et al. (2009) Early and sustained innate immune response defines pathology and death in nonhuman primates infected by highly pathogenic influenza virus. Proc Natl Acad Sci U S A 106: 3455-3460.
17. Kash JC, Tumpey TM, Proll SC, Carter V, Perwitasari O, et al. (2006) Genomic analysis of increased host immune and cell death responses induced by 1918 influenza virus. Nature 443: 578-581.
18. Kash JC, Basler CF, Garc?́a-Sastre A, Carter V, Billharz R, et al. (2004) Global host immune response: Pathogenesis and transcriptional profiling of type A influenza viruses expressing the hemagglutinin and neuraminidase genes from the 1918 pandemic virus. J Virol 78: 9499-9511.
19. Cameron CM, Cameron MJ, Bermejo-Martin JF, Ran L, Xu L, et al. (2008) Gene expression analysis of host innate immune responses during lethal H5N1 infection in ferrets. J Virol 82: 11308-11317.
20. McHardy AC, Adams, B (2009) The role of genomics in tracking the evolution of influenza A virus. PLoS Pathog e1000566: doi:10.1371/journal. ppat.1000566.
21. Tang XC, Zhang JX, Zhang SY, Wang P, Fan XH, et al. (2006) Prevalence and genetic diversity of coronaviruses in bats from China. J Virol 80: 7481-7490.
22. Song HD, Tu CC, Zhang GW, Wang SY, Zheng K, et al. (2005) Cross-host evolution of severe acute respiratory syndrome coronavirus in palm civet and human. Proc Natl Acad Sci U S A 102: 2430-2435.
23. Li W, Zhang C, Sui J, Kuhn JH, Moore MJ, et al. (2005) Receptor and viral determinants of SARS-coronavirus adaptation to human ACE2. EMBO J 24: 1634-1643.
24. Sheahan T, Rockx B, Donaldson E, Sims A, Pickles R, et al. (2008) Mechanisms of zoonotic severe acute respiratory syndrome coronavirus host range expansion in human airway epithelium. J Virol 82: 2274-2285.
25. Rockx B, Baas T, Zornetzer GA, Haagmans B, Sheahan T, et al. (2009) Early upregulation of acute respiratory distress syndrome-associated cytokines promotes lethal disease in an aged-mouse model of severe acute respiratory syndrome coronavirus infection. J Virol 83: 7062-7074.
26. de Lang A, Baas T, Teal T, Leijten LM, Rain B, et al. (2007) Functional genomics highlights differential induction of antiviral pathways in the lungs of SARS-CoV-infected macaques. PLoS Pathog 3: e112. doi:10.1371/journal. ppat.0030112.
27. Baas T, Roberts A, Teal TH, Vogel L, Chen J, et al. (2008) Genomic analysis reveals age-dependent innate immune responses to severe acute respiratory syndrome coronavirus. J Virol 82: 9465-9476.
28. Haagmans BL, Kuiken T, Martina BE, Fouchier RA, Rimmelzwaan GF, et al. (2004) Pegylated interferon-alpha protects type 1 pneumocytes against SARS coronavirus infection in macaques. Nat Med 10: 290-293.
29. Andeweg AC, Haagmans BL, Osterhaus ADME (2008) Virogenomics: The virus -host interaction revisited. Curr Opin Microbiol 11: 1-6.