Chronic right ventricular pressure overload results in a hyperplastic rather than a hypertrophic myocardial response

Journal of Anatomy

Volumn 212, Issue 3, 2008, Pages 286-294

  Leeuwenburgh, Boudewijn P J ^a   Helbing, Willem A ^a   Wenink, Arnold C G ^a   Steendijk, Paul ^a   de Jong, Roos ^a   Dreef, Enno J ^a   Gittenberger de Groot, Adriana C ^a   Baan, Jan ^a   van der Laarse, Arnoud ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Hypertension; Hypertrophy; Morphometry; Myocardial hyperplasia; Right ventricle

Indexed keywords

CYCLINE; DNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL NUCLEUS; CELL PROLIFERATION; CELL STRUCTURE; CONTROLLED STUDY; ENDOCARDIUM; EPICARDIUM; HEART LEFT VENTRICLE HYPERTROPHY; HEART LEFT VENTRICLE PRESSURE; HEART MUSCLE; HEART MUSCLE CELL; HEART RIGHT VENTRICLE HYPERTROPHY; HEART RIGHT VENTRICLE PRESSURE; HEART VOLUME; HYPERPLASIA; IMMUNOHISTOCHEMISTRY; LAMB; MORPHOMETRICS; NONHUMAN; PRIORITY JOURNAL; PULMONARY ARTERY;

ANIMALS; ANIMALS, NEWBORN; CARDIOMYOPATHIES; HEART VENTRICLES; HYPERPLASIA; IMMUNOHISTOCHEMISTRY; LIGATION; MODELS, ANIMAL; MYOCYTES, CARDIAC; PULMONARY ARTERY; SHEEP; VENTRICULAR PRESSURE;

ANIMALIA; OVIS ARIES;

EID: 40149106486     PISSN: 00218782     EISSN: 14697580     Source Type: Journal    
DOI: 10.1111/j.1469-7580.2008.00853.x     Document Type: Article

References (42)

1. Anversa P, Kajstura J (1998) Ventricular myocytes are not terminally differentiated in the adult mammalian heart. Circ Res 83, 1-14.
2. Anversa P, Palackal T, Sonnenblick EH, Olivetti G, Meggs LG, Capasso JM (1990) Myocyte cell loss and myocyte cellular hyperplasia in the hypertrophied aging rat heart. Circ Res 67, 871-85.
3. Anversa P, Capasso JM, Olivetti G, Sonnenblick EH (1992) Cellular basis of ventricular remodeling in hypertensive cardiomyopathy. Am J Hypertens 5, 758-70.
4. Astorri E, Chizzola A, Visioli O, Anversa P, Olivetti G, Vitali-Mazza L (1971) Right ventricular hypertrophy - a cytometric study on 55 human hearts. J Mol Cell Cardiol 2, 99-110.
5. Barbera A, Giraud GD, Reller MD, Maylie J, Morton MJ, Thornburg KL (2000) Right ventricular systolic pressure load alters myocyte maturation in fetal sheep. Am J Physiol Regul Integr Comp Physiol 279, R1157-64.
6. Becker AE (1993) Myocardial hypertrophy and hyperplasia. A narrative of past, present and future. Eur Heart J 14, 1-3.
7. Beinlich CJ, Rissinger CJ, Morgan HE (1995) Mechanisms of rapid growth in the neonatal pig heart. J Mol Cell Cardiol 27, 273-81.
8. Bishop SP, Hine P (1975) Cardiac muscle cytoplasmic and nuclear development during canine neonatal growth. In Recent Advances in Studies on Cardiac Structure and Metabolism (ed. Roy P), vol. 8, pp. 77-98. Baltimore: University Press.
9. Capasso JM, Bruno S, Cheng W, Li P, Rodgers R, Darzynkiewicz Z, Anversa P (1992) Ventricular loading is coupled with DNA synthesis in adult cardiac myocytes after acute and chronic myocardial infarction in rats. Circ Res 71, 1379-89.
10. Clubb FJ Jr, Bishop SP (1984) Formation of binucleated myocardial cells in the neonatal rat. An index for growth hypertrophy. Lab Invest 50, 571-7.
11. Clubb FJ Jr, Penney DG, Baylerian MS, Bishop SP (1986) Cardiomegaly due to myocyte hyperplasia in perinatal rats exposed to 200 ppm carbon monoxide. J Mol Cell Cardiol 18, 477-86.
12. Doering CW, Jalil JE, Janicki JS, Pick R, Aghili S, Abrahams C, et al. (1988) Collagen network remodelling and diastolic stiffness of the rat left ventricle with pressure overload hypertrophy. Cardiovasc Res 22, 686-695.
13. Gerdes AM (2002) Cardiac myocyte remodeling in hypertrophy and progression to failure. J Card Fail 8, S264-8.
14. Grajek S, Lesiak M, Pyda M, Zajac M, Paradowski S, Kaczmarek E (1993) Hypertrophy or hyperplasia in cardiac muscle. Post-mortem human morphometric study. Eur Heart J 14, 40-47.
15. Jeter JR Jr, Cameron IL (1971) Cell proliferation patterns during cytodifferentiation in embryonic chick tissues: Liver, heart and erythrocytes. J Embryol Exp Morphol 25, 405-22.
16. Kajstura J, Mansukhani M, Cheng W, Reiss K, Krajewski S, Reed JC, et al. (1995) Programmed cell death and expression of the protooncogene bcl-2 in myocytes during postnatal maturation of the heart. Exp Cell Res 219, 110-121.
17. Karsten U, Wollenberger A (1977) Improvements in the ethidium bromide method for direct fluorometric estimation of DNA and RNA in cell and tissue homogenates. Anal Biochem 77, 464-470.
18. van der Laarse A, Hollaar L, Vliegen HW, Egas JM, Dÿkshoom NJ, Cornelisse CJ, et al. (1989) Myocardial (iso)enzyme activities, DNA concentration and nuclear polyploidy in hearts of patients operated upon for congenital heart disease, and in normal and hypertrophic adult human hearts at autopsy. Eur J Clin Invest 19, 192-200.
19. Leeuwenburgh BPJ, Helbing WA, Steendijk P, Schoof PH, Baan J (2001) Biventricular systolic function in young lambs subject to chronic systemic right ventricular pressure overload. Am J Physiol Heart Circ Physiol 281, H2697-H2704.
20. Leeuwenburgh BPJ, Steendijk P, Helbing WA, Baan J (2002) Indexes of diastolic RV function: Load dependence and changes after chronic RV pressure overload in lambs. Am J Physiol Heart Circ Physiol 282, H1350-H1358.
21. Li F, Wang X, Capasso JM, Gerdes AM (1996) Rapid transition of cardiac myocytes from hyperplasia to hypertrophy during postnatal development. J Mol Cell Cardiol 28, 1737-46.
22. MacLellan WR, Schneider MD (1997) Death by design. Programmed cell death in cardiovascular biology and disease. Circ Res 81, 137-44.
23. Marino TA, Haldar S, Williamson EC, Beaverson K, Walter RA, Marino DR, et al. (1991) Proliferating cell nuclear antigen in developing and adult rat cardiac muscle cells. Circ Res 69, 1353-60.
24. Matturri L, Milei J, Grana DR, Lavezzi AM (2002) Characterization of myocardial hypertrophy by DNA content, PCNA expression and apoptotic index. Int J Cardiol 82, 33-9.
25. Nadal-Ginard B, Kajstura J, Leri A, Anversa P (2003) Myocyte death, growth, and regeneration in cardiac hypertrophy and failure. Circ Res 92, 139-50.
26. Narula J, Haider N, Virmani R, DiSalvo TG, Kolodgie FD, Hajjar RJ, et al. (1996) Apoptosis in myocytes in end-stage heart failure. N Engl J Med 335, 1182-9.
27. Norton AJ (1993) Microwave oven heating for antigen unmasking in routinely processed tissue sections. J Pathol 171, 79-80.
28. Olivetti G, Ricci R, Anversa P (1987) Hyperplasia of myocyte nuclei in long-term cardiac hypertrophy in rats. J Clin Invest 80, 1818-21.
29. Olivetti G, Ricci R, Lagrasta C, Maniga E, Sonnenblick EH, Anversa P (1988) Cellular basis of wall remodeling in long-term pressure overload-induced right ventricular hypertrophy in rats. Circ Res 63, 648-657.
30. Olivetti G, Melissari M, Balbi T, Quaini F, Sonnenblick EH, Anversa P (1994) Myocyte nuclear and possible cellular hyperplasia contribute to ventricular remodeling in the hypertrophic senescent heart in humans. J Am Coll Cardiol 24, 140-9.
31. Olivetti G, Abbi R, Quaini F, Kajstura J, Cheng W, Nitahara JA, et al. (1997) Apoptosis in the failing human heart. N Engl J Med 336, 1131-41.
32. Oparil S, Bishop SP, Clubb FJ Jr (1984) Myocardial cell hypertrophy or hyperplasia. Hypertension 6, III38-43.
33. Pasumarthi KB, Field LJ (2002) Cardiomyocyte cell cycle regulation. Circ Res 90, 1044-54.
34. Poolman RA, Li JM, Durand B, Brooks G (1999) Altered expression of cell cycle proteins and prolonged duration of cardiac myocyte hyperplasia in p27KIP1 knockout mice. Circ Res 85, 117-27.
35. Rakusan K (1984) Cardiac growth, maturation and aging. In Growth of the Heart in Health and Disease (ed. Zak R), pp. 131-164. New York: Raven.
36. Saiki Y, Konig A, Waddell J, Rebeyka IM (1997) Hemodynamic alteration by fetal surgery accelerates myocyte proliferation in fetal guinea pig hearts. Surgery 122, 412-9.
37. Sedmera D, Hu N, Weiss KM, Keller BB, Denslow S, Thompson RP (2002) Cellular changes in experimental left heart hypoplasia. Anat Rec 267, 137-45.
38. Sedmera D, Thompson RP, Kolar F (2003) Effect of increased pressure loading on heart growth in neonatal rats. J Mol Cell Cardiol 35, 301-9.
39. Thiedemann KU, Holubarsch C, Medugorac I, Jacob R (1983) Connective tissue content and myocardial stiffness in pressure overload hypertrophy. A combined study of morphologic, morphometric, biochemical, and mechanical parameters. Basic Res Cardiol 78, 140-155.
40. Vliegen HW, Bruschke AV, Van der Laarse A (1990) Different response of cellular DNA content to cardiac hypertrophy in human and rat heart myocytes. Comp Biochem Physiol A 95, 109-14.
41. Vliegen HW, van der Laarse A, Cornelisse CJ, Eulderink F (1991) Myocardial changes in pressure overload-induced left ventricular hypertrophy. A study on tissue composition, polyploidization and multinucleation. Eur Heart J 12, 488-494.
42. Weibel ER (1979) In Stereological Methods, vol. 1: Practical Methods for Biological Morphometry. London: Academic Press.