Toll-like Receptors (TLRs) are expressed by myeloid leukaemia cell lines, but fail to trigger differentiation in response to the respective TLR ligands: Correspondence

British Journal of Haematology

Volumn 147, Issue 4, 2009, Pages 585-587

  Okamoto, Masashi ^a   Hirai, Hideyo ^a   Taniguchi, Kyoko ^a   Shimura, Kazuho ^a   Inaba, Tohru ^a   Shimazaki, Chihiro ^a   Taniwaki, Masafumi ^a   Imanishi, Jiro ^a  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

Author keywords

Differentiation therapy; Infection; Myeloid leukaemia; Toll like receptor

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8;

CANCER REGRESSION; CELL DIFFERENTIATION; CELL PROLIFERATION; HUMAN; LETTER; LEUKEMIA CELL LINE; MYELOID LEUKEMIA; NONHUMAN; PRIORITY JOURNAL;

CELL DIFFERENTIATION; HUMANS; LEUKEMIA, MYELOID; LIGANDS; NEOPLASM PROTEINS; TOLL-LIKE RECEPTORS; TUMOR CELLS, CULTURED;

EID: 70350464151     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2009.07858.x     Document Type: Letter

References (10)

1. Bohnhorst, J., Rasmussen, T., Moen, S.H., Flottum, M., Knudsen, L., Borset, M., Espevik, T. Sundan, A. (2006) Toll-like receptors mediate proliferation and survival of multiple myeloma cells. Leukemia, 20, 1138 1144.
2. Ifrah, N., James, J., Viguie, F., Marie, J. Zittoun, R. (1985) Spontaneous remission in adult acute leukemia. Cancer, 56, 1187 1190.
3. Iwasaki, A. Medzhitov, R. (2004) Toll-like receptor control of the adaptive immune responses. Nature Immunology, 5, 987 995.
4. Kawai, T. Akira, S. (2006) TLR signaling. Cell Death and Differentiation, 13, 816 825.
5. Lachant, N.A., Goldberg, J., Nelson, D.A. Gottlieb, A.J. (1979) Spontaneous remission in acute myelogenous leukemia in the adult. American Journal of Medicine, 67, 687 692.
6. Maywald, O., Buchheidt, D., Bergmann, J., Schoch, C., Ludwig, W.D., Reiter, A., Hastka, J., Lengfelder, E. Hehlmann, R. (2004) Spontaneous remission in adult acute myeloid leukemia in association with systemic bacterial infection-case report and review of the literature. Annals of Hematology, 83, 189 194.
7. McGettrick, A.F. O'Neill, L.A. (2007) Toll-like receptors: key activators of leucocytes and regulator of haematopoiesis. British Journal of Haematology, 139, 185 193.
8. Nagai, Y., Garrett, K.P., Ohta, S., Bahrun, U., Kouro, T., Akira, S., Takatsu, K. Kincade, P.W. (2006) Toll-like receptors on hematopoietic progenitor cells stimulate innate immune system replenishment. Immunity, 24, 801 812.
9. Sioud, M., Floisand, Y., Forfang, L. Lund-Johansen, F. (2006) Signaling through toll-like receptor 7/8 induces the differentiation of human bone marrow CD34+ progenitor cells along the myeloid lineage. Journal of Molecular Biology, 364, 945 954.
10. Spaner, D.E. Masellis, A. (2007) Toll-like receptor agonists in the treatment of chronic lymphocytic leukemia. Leukemia, 21, 53 60.