Melatonin and oxidative stress

Revista Espanola de Enfermedades Digestivas

Volumn 101, Issue 7, 2009, Pages 453-459

  Solis Herruzo J A ^a   Solis Munoz P ^a  

^a HOSPITAL UNIVERSITARIO 12 DE OCTUBRE   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; ALPHA TOCOPHEROL; ASCORBIC ACID; MELATONIN; REACTIVE OXYGEN METABOLITE; NITRATE; NITRIC OXIDE; PEROXIDE;

CHOLESTASIS; DRUG MECHANISM; DRUG PENETRATION; EDITORIAL; HUMAN; LIVER DISEASE; NITROSATIVE STRESS; NONHUMAN; OXIDATIVE STRESS; METABOLISM; NOTE; PHYSIOLOGY;

HUMANS; MELATONIN; NITRATES; NITRIC OXIDE; OXIDATIVE STRESS; PEROXIDES;

EID: 70350444997     PISSN: 11300108     EISSN: None     Source Type: Journal    
DOI: 10.4321/S1130-01082009000700001     Document Type: Editorial

References (86)

1. Norenberg MD, Jayakumar AR, Rama Rao KV. Oxidative stress in the pathogenesis of hepatic encephalopathy. Metab Brain Dis 2004; 19: 313-29.
2. Cruz A, Tasset I, Ramírez LM, Arjona A, Segura J, Túnez I, et al. Effect of melatonin on myocardial oxidative stress induced by experimental obstructive jaundice. Rev Esp Enferm Dig 2009; 101: 460-3.
3. Padillo FJ, Rodríguez M, Gallardo JM, Andicoberry B, Naranjo A, Miño G, et al. Preoperative assessment of body fluid disturbances in patients with obstructive jaundice. Word J Surg 1999; 23: 681-7.
4. Padillo J, Puente J, Gómez M, Dios F, Naranjo A, Vallejo JA, et al. Improved cardiac function in patients with obstructive jaundice after internal biliary drainage. Hemodynamic and hormonal assessment. Ann Surg 2001; 234: 652-6.
5. Better OS, Bomzon A. Effects of jaundice on the renal and cardiovascular systems. In: Epstein M, editor. The Kidney in Liver Disease. 3rd ed. Baltimore: Willians & Wilkins; 1988. p. 508-34.
6. Sam F, Kerstetter DL, Pimental DR, Mulukutla S, Tabaee A, Bristow MR, et al. Increased reactive oxygen species production and functional alterations in antioxidant enzymes in human mailing myocardium. Congest Heart Fail 2005; 11: 2130-44.
7. Montilla P, Cruz A, Padillo FJ, Túnez I, Gascón F, Muñoz MC, et al. Melatonin versus vitamin E as protective treatment against oxidative stress after extrahepatic bile duct ligation in rats. J Pineal Res 2001; 31: 135-9.
8. Cruz A, Túnez I, Martínez R, Muñoz-Castañeda JR, Ramírez LM, Recio M, et al. Melatonin prevents brain oxidative stress induced by obstructive jaundice in rats. J Neurosci Res 2007; 85: 3652-6.
9. Pastor A, Collado PS, Almar M, González-Gallego J. Antioxidant enzyme status in biliary obstructed rats: effects of N-acetylcysteine. J Hepatol 1997; 27: 363-370.
10. Chroni E, Patsoukis N, Karageorgos N, Konstantinou D, Georgiou G. Brain oxidative stress induced by obstructive jaundice in rats. J Neuropathol Exp Neurol 2006; 65: 193-8.
11. Ljubuncic P, Tanne Z, Bomzon A. Evidence of a systemic phenomenon for oxidative stress in cholestasic liver disease. Gut 2000; 47: 710-6.
12. Assimakopoulos SF, Thomopoulos KC, Patsoukis N, Georgiou CD, Scopa CD, Nikolopoulou VN, et al. Evidence for intestinal oxidative stress in patients with obstructive jaundice. Eur J Clin Invest 2006; 36: 181-7.
13. Radi R, Beckman JS, Bush KM, Freeman BA, Peroxynitrite oxidation of sulphydryls. The cytotoxic potential of superoxide and nitric oxide. J Biol Chem 1991; 266: 4244-50.
14. Pryor WA, Squadrito GL. The chemistry of peroxynitrite: a product from the reaction of nitric oxide with superoxide. Am J Physiol 1995; 268: L699-722.
15. Lymar SV, Hurst JK. Rapid reaction between peroxynitrite ion and carbon dioxide: Implications for biological activity. J Am Chem Soc 1995; 117: 8867-8.
16. Beckman JS, Ischiropoulos H, Zhu L, van der Waal M, Smith C, Chen J, et al. Kinetics of superoxide dismutase-an iron catalyzed nitration of phenolics by peroxynitrite. Arch Biochem Biophys 1992; 298: 438-55.
17. Whiteman M, Tritschler H, Halliwell B. FEBS Lett 1996; 379: 74-6.
18. Crow JP, Beckman JS, McCrod JM. Sensitivity of the zinc-thiolate mioety of yeast alcohol dehydrogenase to hypochorite and peroxynitrite, Biochemistry 1995; 34: 3544-52.
19. Radi R, Beckman JS, Bush KM, Freeman BA. Peroxynitrite induced membrane lipid peroxidation. The cytotoxic potential of superoxide and nitric oxide, Arch Biochem Biophys 1991; 288: 481-7.
20. Moreno JJ, Pryor WA. Inactivation of α1-proteinase inhibitor by peroxynitrate. Chem Res Toxic 1992; 5: 425-31.
21. King PA, Anderson VE. Edwards JO, Gustafson G, Plumb RC, Sugus JW. A stable solid that generates hydroxyl radical upon dissolution in aqueous solution: reaction with proteins and nucleic acids. J Am Chem Soc 1992; 114: 5430-2.
22. QiW, Reiter RJ, Tan DX, Manchester LC, Siu AW, García JJ. Increased levels of oxidatively damaged DNA induced by chromium (III) and H2O2: protection by melatonin and related molecules. J Pineal Res 2000; 29: 54-61.
23. Radi R, Cassina A, Hodara R, Quijano C, Castro L. Peroxynitrite reactions and formation in mitochondria. Free Radi Biol Med 2002; 33: 1451-64.
24. García-Ruiz I, Rodríguez-Juan C, Díaz-Sanjuan T, del Hoyo P, Colina F, Muñoz-Yagüe T, et al. Uric acid and anti-TNF antibody improve mitochondrial dysfunction in ob/ob mice. Hepatology 2006; 44: 581-591.
25. García-Ruiz I, Fernández-Moreira D, Rodríguez-Juan C, Díaz-Sanjuán T, Muñoz-Yagüe Mt, Solís- Muñoz P, et al. Peroxynitrite inhibits mitochondrial respiratory chain (Mrc) and reproduces functional and proteomic alterations found in mitochondria from Ob/Ob mice. Hepatology 2008; 48 (Supl.): 843A.
26. Yermilov V, Yoshie Y, Rubio J, Ohshima H. Effects of carbon dioxide/bicarbonate on induction of DNA single-strand breaks and formation of 8-nitroguanine, 8-oxoguanine and base-propenal mediated by peroxynitrite. FEBS Lett. 1996; 399: 67-70.
27. Chien YH, Bau DT, Jan KY. Nitric oxide inhibits DNA-adduct excision in nucleotide excision repair. Free Radic Biol Med 2004; 36: 1011-7.
28. MacMillan-Crow LA, Crow JP, Thompson JA. Peroxynitrite-mediated inactivation of manganese superoxide dismutase involves nitration and oxidation of critical tyrosine residues. Biochemistry 1998; 37: 1613-22.
29. Szabo C. Multiple pathways of peroxynitrite cytotoxicity. Toxicol Lett 2003; 140-1: 105-12.
30. Darley-Usmar V, Wiseman H, Halliwell B. Nitric oxide and oxygen radicals: a question of balance. FEBS Lett 1995; 369: 131-5.
31. Kong SK, Yim MB, Stadtman ER, Chock PB. Peroxynitrite disables the tyrosine phosphorylation regulatory mechanism: Lymphocyte-specific tyrosine kinase fails to phosphorylate nitrated cdc2(6-20)NH2 peptide. Proc Natl Acad Sci USA 1996; 93: 3377-82.
32. Pacher P, Beckman JS, Liaudet L. Nitric oxide and peroxynitrite in health and disease. Physiol Rev 2007; 87: 315-424.
33. Krahenbuhl S, Talos C, Reichen J. Mechanisms of impaired hepatic fatty acid metabolism in rats with longterm bile Duch ligation. Hepatology 1994; 19: 1272-81.
34. Krahenbuhl L, Schafer M, Krahenbuhl S. Reversibility of hepatic mitochondrial damage in rats with longterm cholestasis. J Hepatol 1998; 28: 1000-7.
35. Perez MJ, Macias RI, Duran C, Monte MJ, Gonzalez-Buitrago JM, Marin JJ. Oxidative stress and apoptosis in fetal rat liver induced by maternal cholestasis. Protective effect of ursodeoxycholic acid. J Hepatol 2005; 43: 324-32.
36. Singh S, Shackleton G, Ah-Sing E, Chakraborty J, Bailey ME. Antioxidant defensas in the bile Duch-ligated rat. Gastroenterology 1992; 103: 1625-9.
37. Esrefoglu M, Gül M, Emre MH, Polat A, Selimoglu MA. Protective effect of low dose of melatonin against cholestatic oxidative stress after common bile duct ligation in rats. World J Gastroenterol 2005; 11: 1951-6.
38. Engin A, Bozkurt B, Altan N, Memis L, Bukan N. Nitric oxide-mediated liver injury in the presence of experimental bile duct obstruction. World J Surg 2003; 27: 253-5.
39. Mustafa GM, Cowger ML, Kings TE. Effects of bilirubin on mitochondrial reactions. J Biol Chem 1969; 344: 6403-14.
40. Krahenbuhl S, Stucki J, Reichen J. Reduced activity of the electrón transport Chain in liver mitochondria isolated from rats with secondary biliary cirrhosis. Hepatology 1992; 15: 1160-6.
41. Van Blitterswijk WJ, van der Meer BW, Hilkmann H. Quantitative contributions of cholesterol and the individual classes of phospholipids and their degree of fatty acyl (un)saturation to membrane fluidity measured by fluorescence polarization.Biochemistry 1987; 26: 1746-56.
42. Sokol RJ, Winklhofer-Roob BM, Devereaux MW, McKim JM Jr. Generation of hydroperoxides in isolated rat hepatocytes and hepatic mitochondria exposed to hydrophobic bile acids. Gastroenterology 1995; 109: 1249-56.
43. Schmucker DL, Ohta M, Kanai S, Sato Y, Kitani K. Hepatic injury induced by bile salts: correlation between biochemical and morphological events. Hepatology 1990; 12: 1216-21.
44. Huang YT, Hsu YC, Chen CJ, Liu CT, Wei YH. Oxidative stress-related changes in the livers of bile-duct ligated rats. J Biomed Sci 2003; 10: 170-8.
45. Reiter RJ. Pineal melatonin: Cell biology of its synthesis and of its physiological interactions. Endocr Rev 1991; 12: 151-80.
46. Huether G, Poeggeler B, Reimer A, George A. Effect of tryptophan on circulating melatonin levels in chicks and rats: Evidence for stimulation of melatonin synthesis and release in the gastrointestinal tract. Life Sci 1993; 51: 945-53.
47. Tan DX, Manchester LC, Reiter RJ, Qi L, Zhang M, Weintraub ST, et al. Identification of highly elevated levels of melatonin in bone marrow: its origin and significance. Biochem Biophys Acta 1999; 1472: 206-14.
48. Reiter RJ. The melatonin rhythm: both a clock and a calendar. Experientia 1993; 49: 654-64.
49. Maestroni GJM. T-helper-2 lymphocytes as a peripheral target of melatonin. J Pineal Res 1995; 18: 84-9.
50. Shiu SYW, Li L, Xu JN, Pang CS, Wong JTY, Pang SF. Melatonin induced inhibition of proliferation and G1:S cell cycle transition delay of human choriocarcinoma JAr cells: possible involvement of MT2 (MEL1B) receptor. J Pineal Res 1999; 27: 183-92.
51. Cuzzocrea S, Zingarelli B, Gilad E, Hake P, Salzman AL, Szabo C. Protective effect of melatonin in carrageenaninduced models of local inflammation: Relationship to its inhibitory effect on nitric oxide production and its peroxynitrite scavenging activity. J Pineal Res 1997: 23: 106-16.
52. Tan DX, Manchester LC, Reiter RJ, Plummer BF, Hardies LJ, Weintraub ST, et al. A novel melatonin metabolite, cyclic 3-hydroxymelatonin: a biomarker of in vivo, hydroxyl radical generation. Biochem Biophys Res Commun 1998; 253: 614-70.
53. Stascia P, Ulanski P, Rosiak JM. Melatonin as a hydroxyl radical scavenger. J Pineal Res 1998; 25: 65-6.
54. Lee MC, Chung YT, Lee JH, Jung JJ, Kim HS, Kim SU. Antioxidant effect of melatonin in human retinal neuron cultures. Exp Neurol 2001; 172: 407-15.
55. Baron V, Muriel P. Role of glutathione, lipid peroxidation and antioxidants on acute bile-duct obstruction in the rat. Biochim Biophys Acta 1999; 1472: 173-80.
56. Montilla P, Cruz A, Padillo FJ, Tunez I, Gascon F, Munoz MC, et al. Melatonin versus vitamin E as protective treatment against oxidative stress after extra-hepatic bile duct ligation in rats. J Pineal Res 2001; 31: 138-44.
57. Ohta Y, Kongo M, Kishikawa T. Melatonin exerts a therapeutic effect on cholestatic liver injury in rats with bile duct ligation. J Pineal Res 2003; 34: 119-26.
58. Bülbüller N, Akkup MA, Cetinkaya Z, Ilhan YS, Özercan I, Kýrkýl C, et al. Effects of melatonin and lactulose on theliver and kidneys in rats with obstructive jaundice. Pediatr Surg Int 2002; 18: 677-80.
59. Peyrot F, Houee-Levin C, Ducrocq C. Melatonin nitrosation promoted by NO*2; comparison with the peroxynitrite reaction. Free Radic Res 2006; 40: 910-20.
60. Soung DY, Choi HR, Kim JY, No JK, Lee JH, Kim MS, et al. Peroxynitrite scavenging activity of indole derivatives: interaction of indoles with peroxynitrite. J Med Food 2004; 7: 84-9.
61. Blanchard B, Denis Pompon D, Ducrocq C. Nitrosation of melatonin by nitric oxide and peroxynitrite. J. Pineal Res 2000; 29: 184-92.
62. Wang JZ, Wang ZF. Role of melatonin in Alzheimer-like neurodegeneration. Acta Pharmacol Sin 2006; 27: 41-9.
63. Ucar M, Korkmaz A, Reiter RJ, Yaren H, Oter S, Kurt B, et al. Melatonin alleviates lung damage induced by the chemical warfare agent nitrogen mustard. Toxicol Lett. 2007; 173: 124-31.
64. Tan DX, Manchester LC, Reiter RJ, Plummer BF, Hardies LJ, Weintraub ST, et al. A novel melatonin metabolite, cyclic 3-hydroxymelatonin: a biomarker of in vivo hydroxyl radical generation. Biochem Biophys Res Commun 1998; 253: 614-20.
65. Reiter RJ, Tang L, García JJ, Muñoz-Hoyos A. Pharmacological actions of melatonin in oxygen radical pathophysiology. Life Sci 1997; 60: 2255-71 .
66. Dugo L, Serraino I, Fulia F, De Sarro A, Caputi AP, Cuzzocrea S. Effect of melatonin on cellular energy depletion mediated by peroxynitrite and poly (ADP-ribose) synthetase activation in an acute model of inflammation. J Pineal Res 2001; 31: 76-84.
67. Tan DX, Manchester LC, Sainz RM, Mayo JC, Leon J, Hardeland R, et al. Interactions between melatonin and nicotinamide nucleotide: NADH preservation in cells and in cell-free systems by melatonin. J Pineal Res 2005; 39: 185-94.
68. López LC, Escames G, Ortiz F, Ros E, Acuña-Castroviejo D. Melatonin restores the mitochondrial production of ATP in septic mice. Neuro Endocrinol Lett 2006; 27: 623-30.
69. Barlow-Walden LR, Reiter RJ, Abe M, Pablos M, Menéndez- Peláez A, Chen LD, et al. Melatonin stimulates brain glutathione peroxidase activity. Neurochem Int 1995; 26: 497-502.
70. Bettahi I, Pozo D, Osuna C, Reiter RJ, Acuña-Castroviejo D, Guerrero JM. Melatonin reduces nitric oxide synthase activity in rat hypothalamus. J Pineal Res 1996; 20: 205-10.
71. Winiarska K, Fraczyk T, Malinska D, Drozak J, Bryla J. Melatonin attenuates diabetes-induced oxidative stress in rabbits. J Pineal Res 2006; 40: 168-76.
72. Rodríguez C, Mayo JC, Sainz RM, Antolín I, Herrera F, Martín V, et al. Regulation of antioxidant enzymes: a significant role for melatonin. J Pineal Res 2004; 36: 1-9.
73. Reiter RJ, Tan DX, Maldonado MD. Melatonin as an antioxidant: physiology versus pharmacology. J Pineal Res 2005; 39: 215-6.
74. Dong WG, Mei Q, Yu JP, Xu JM, Xiang L, Xu Y, et al. Effects of melatonin on the expression of iNOS and COX-2 in rat models of colitis. World J Gastroenterol 2003; 9: 1307-11.
75. Rodríguez MI, Carretero M, Escames G, López LC, Maldonado MD, Tan DX, et al. Chronic melatonin treatment prevents age-dependent cardiac mitochondrial dysfunction in senescence-accelerated mice. Free Radic. Res. 2007; 41: 15-24.
76. López LC, Escames G, Tapias V, Utrilla P, León J, Acuña-Castroviejo D. Identification of an inducible nitric oxide synthase in diaphragm mitochondria from septic mice: its relation with mitochondrial dysfunction and prevention by melatonin. Int J Biochem Cell Biol 2006; 38: 267-78.
77. Okatani Y, Okamoto K, Hayashi K, Wakatsuki A, Sagara Y. Maternal-fetal transfer of melatonin in human pregnancy near term. J Pineal Res 1998; 25: 129-34.
78. Reiter RJ. Melatonin: lowering the high price of free radicals. News Physiol Sci 2000; 15: 246-50.
79. Antolín I, Rodríguez C, Sainz RM, Mayo JC, Uría H, Kotler ML, et al. Neurohormone melatonin prevents cell damage: effect on gene expression for antioxidant enzymes. FASEB J 1996; 10: 882-90.
80. Reiter RJ. Oxidative damage in the central nervous system: protection by melatonin. Prog Neurobiol 1998; 56: 359-84.
81. Reppert SM, Weaver DR, Godson C. Melatonin receptors step into the light: cloning and classification of subtypes. Trends Pharmacol Sci 1996; 17: 100-2.
82. Li JH, Yu JP, Yu HG, Xu XM, Yu LL, Liu J, et al. Melatonin reduces inflammatory injury through inhibiting NF-kappaB activation in rats with colitis. Mediators Inflamm 2005: 185-93.
83. Tan DX, Reiter RJ, Manchester LC, Yan MT, El-Sawi M, Sainz RM, et al. Chemical and physical properties and potential mechanisms: melatonin as a broad spectrum antioxidant and free radical scavenger. Curr Top Med Chem 2002; 2: 181-97.
84. Forrest CM, Mackay GM, Stoy N, Stone TW, Darlington LG. Inflammatory status and kynurenine metabolism in rheumatoid arthritis treated with melatonin. Br J Clin Pharmacol 2007; 64: 517-26.
85. Kedziora-Kornatowska K, Szewczyk-Golec K, Czuczejko J, Pawluk H, van Marke de Lumen K, Kozakiewicz M, et al. Antioxidative effects of melatonin administration in elderly primary essential hypertension patients. J Pineal Res 2008; 45: 312-7.
86. Benot S, Goberna R, Reiter RJ, García-Mauriño S, Osuna C, Guerrero JM. Physiological levels of melatonin contribute to the antioxidant capacity of human capacity of human serum. J Pineal Res 1999; 27: 59-64.