Effects of Allium hirtifolium (Iranian shallot) and its allicin on microtubule and cancer cell lines

African Journal of Biotechnology

Volumn 8, Issue 19, 2009, Pages 5030-5037

  Azadi, Hamideh Ghodrati ^a   Riazi, Gholam Hossein ^b   Ghaffari, Seyed Mahmood ^b   Ahmadian, Shahin ^b   Khalife, Tahereh Javdani ^b  

^a FERDOWSI UNIVERSITY OF MASHHAD   (Iran)

^b UNIVERSITY OF TEHRAN   (Iran)

Author keywords

Allium hirtifolium; Cell proliferation; Microtubule assembly dynamic; SH containing protein; Tubulin

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ALLICIN; ALLIUM HIRTIFOLIUM EXTRACT; ANTINEOPLASTIC AGENT; PLANT EXTRACT; TUBULIN; UNCLASSIFIED DRUG;

ALLIUM HIRTIFOLIUM; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CONTROLLED STUDY; DEPOLYMERIZATION; DRUG ACTIVITY; HUMAN; HUMAN CELL; IC 50; MICROTUBULE ASSEMBLY; MOUSE; NONHUMAN; SHALLOT; TRANSMISSION ELECTRON MICROSCOPY; TURBIDIMETRY;

ALLIACEAE; ALLIUM; ALLIUM ASCALONICUM; ALLIUM HIRTIFOLIUM; OVIS ARIES;

EID: 70350433921     PISSN: None     EISSN: 16845315     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. Allan VJ, Vale RD (1991). Cell cycle control of microtubule-based membrane transport and tubule formation in vitro. J. Cell Biol. 113: 347-359.
2. Attard G, Greystoke A, Kaye S, De Bono J (2006). Update on tubulin-binding agents. Pathologie Biologie 54(2): 72-84.
3. Barile E, Capasso R, Izzo AA, Lanzotti V, Sajjadi SE, Zolfaghari B (2005). Structure-Activity Relationships for Saponins from Allium hirtifolium and Allium elburzense and their Antispasmodic Activity. Planta Med. 71: 1010-1018.
4. Block E, Naganathan S, Putman D, Zhao SH (1992). Allium chemistry: HPLC Analysis of thiosulfinates from onion, garlic, wild garlic (ramsoms), leek, scallion, shallot, elephant (great-headed) garlic. J. Agric. Food Chem. 40: 2418-2430.
5. Bogdan C, Ding A (1992). Taxol, a microtubule-stabilizing antineoplastic agent, induces expression of tumor necrosis factor alpha and interleukin-1 in macrophages. J. Leukocyte Biol. 52(1): 119-121.
6. Bozzoll J (2001). Principles and techniques for biologists, 2nd ed: p. 553.
7. Castoldi M, Popov AV (2003). Purification of brain tubulin through two cycles of polymerization-depolymerization in a high-molarity buffer Protein Expression and Purification 32(1): 83-88.
8. Deplanque G, Harris AL (2000). Anti-angiogenic agents clinical trial design and therapies in development. Eur. J. Cancer 36(13): 1713-1724. (Pubitemid 30616375)
9. Dhamodharan R, Jordan MA, Thrower D, Wilson L, Wadsworth P (1995). Vinblastine suppresses dynamics of individual microtubules in living interphase cells. Mol. Biol. Cell 6(90): 1215-1229.
10. Downing KH, Nogales E (1998). Tubulin and microtubule structure. Curr. Opin. Cell Biol. 10(1): 16-22.
11. Gaskin F, Cantor CR, Shelanski ML (1974). Turbidimetric studies of the in vitro assembly and disassembly of porcine neurotubules. J. Mol. Biol. 89: 737-755.
12. Herrmann M, Lorenz HM (1994). A rapid and simple method for the isolation of apoptotic DNA fragments. Nucl. Acids Res. 22(24): 5506-5507.
13. Ihara T, Arai K, Kaziro Y (1975). Purification of tubulin from bovine brain and its interaction with guanine nucleotides. J. Biochem. 77: 647-658.
14. Jafarian A, Ghannadi A, Elyasi A (2003). The effects of Allium hirtifolium Boiss. on cell-mediated immune response in mice. Iranian J. Pharm. Res. 2: 51-55.
15. Jordan MA, Wilson L (1998). Microtubules and actin filaments: dynamic targets for cancer chemotherapy. Curr. Opin. Cell, 10: 123-130.
16. Jordan MA, Wilson L (2004 ). Microtubules as a target for anticancer Drugs. Nat. Rev. Cancer, 4: 253-265.
17. Karjala G, Chin Q, Manzo E, Andersen RJ, Roberge M (2005). Ceramines, structurally simple microtubule-stabilizing antimitotic agents with unusual cellular effects. Cancer Res. 65(8): 3040-3043. (Pubitemid 40524581)
18. Karki S, Holzbaur ELF (1999). Cytoplasmic dynein and dynactin in cell division and intracellular transport. Curr. Opin. Cell Biol. 11(1): 45-53.
19. Khoutorsky MP, Goncharov I, Rabinkov A, Mirelman D, Geiger B, Bershadsky AD (2007). Allicin inhibits cell polarization, migration and division via its direct effect on microtubules. Cell Motility Cytoskeleton, 64(5): 321-337. (Pubitemid 46608667)
20. Knowles LM, Milner JA (2001). Possible mechanism by which allyl sulfides suppress neoplastic cell proliferation. J. Nutr 131: 1061S-1066S.
21. Kruczynski A, Barret JM, Etievant C, Colpaert F, Fahy J, Hill BT (1998). Antimitotic and tubulin-interacting properties of vinflunine, a novel fluorinated Vinca alkaloid. Biochem. Pharmacol. 55: 635-648.
22. Lawson LD, Wood SG, Hughes BG (1991). HPLC Analysis of Allicin and Other Thiosulfinates in Garlic Clove Homogenates. Planta Med. 57: 263-270.
23. Milner JA (1996). Garlic: its anticarcinogenic and antitumorigenic properties. Nutr. Rev. 54: S82-86.
24. Miron T, Shin I, Feigenblat G, Weiner L, Mirlman D (2002). A spectrophotometric assay for allicin, alliin, and alliinase (alliin lyase) with a chromogenic thiol: reaction of 4-mercaptopyridine with thiosulfinates. Anal. Biochem. 307(1): 76-83.
25. Mosmann T (1983). Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Method, 65: 55-63.
26. Nickerson JA, Wells WW (1984). The microtubule-associated nucleoside diphosphate kinase. J. Biol. Chem. 259(18): 11297-11304.
27. Nogales E (2001). Structural insight into microtubule function. Ann. Rev Biophys. Biomol. Struct. 30: 397-420.
28. Ogra Y, Ishiwata K (2005). Simultaneous speciation of selenium and sulfur species in selenized odorless garlic (Allium sativum L. Shiro) and shallot (Allium ascalonicum) by HPLC-inductively coupled plasma-octopole reaction system-mass spectrometry and electrospray ionization-tandem mass spectrometry. J. Chromatogr. A 1093(1-2): 118-125.
29. Polizzi D, Pratesi G, Tortoreto M, Supino R, Riva A, Bombardelli E, Zunino FA (1999). Novel Taxane with Improved Tolerability and Therapeutic Activity in a Panel of Human Tumor Xenografts. Cancer Res. 59: 1036-1040. (Pubitemid 29135963)
30. Singh SV, Mohan RR, Agarwal R (1996). Novel anti-carcinogenic activity of an organosulfide from garlic: inhibition of H-RAS oncogene transformed tumor growth in vivo by diallyl disulfide is associated with inhibition of p21H-ras processing. Biochem. Biophys. Res. Commun. 225: 660-665.
31. Stracke R, Bohm KJ, Burgold J, Schacht HJ, Unger E (2000). Physical and technical parameters determining the functioning of a kinesin-based cell-free motor system. Nanotechnology, 11: 52-56. (Pubitemid 30887005)
32. Verdier PP, Gares M, Wright M (1999). Differential in vitro association of Vinca alkaloid-induced tubulin spiral filaments into aggregated spirals. Biochem. Pharmacol. 58: 959-971.
33. Williams RC, Lee JC (1982). Methods in enzymology vol. 85. Academic press, pp. 376-392.
34. Wilson L, Jordan MA (1995). Microtubule dynamics: taking aim at a moving target. Chem. Biol. 2(9): 569-573.
35. Xiao D, Pinto JT, Soh JW, Deguchi A, Gundersen GG, Palazzo AF, Yoon JT, Shirin H, Weinstein IB (2003). Induction of Apoptosis by the Garlic-Derived Compound S-Allylmercaptocysteine (SAMC) Is Asso ciated with Microtubule Depolymerization and c-Jun NH2-Terminal Kinase 1 Activation. Cancer Res. 63: 6825-6837. (Pubitemid 37322965)
36. Zhai Y, Kronebusch PJ, Borisy GG (1995). Kinetochore microtubule dynamics and the metaphase-anaphase transition. J. Cell Biol. 131: 721-734.
37. Zhou JC, Gao Y, Lau J, Hamasaki T, Hu E, Dunn B (2007). Nanoscale assembly of gold nanowires templated by microtubules. J. Phys. pp. 1352-1356.